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All Journal Indonesian Journal of Pharmaceutical Science and Technology Bantenese Jurnal Pengabdian Masyarakat Jurnal Ilmiah Kesehatan Sandi Husada Jurnal Analis Kesehatan Kendari Jurnal Ilmiah Kesehatan Sandi Husada (JIKSH)
Bonni Rubak
Politeknik Bina Husada Kendari
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Edukasi Infeksi Kecacingan dan Pemeriksaan Telur Soil Transmited Helminth (STH) Pada Anak-Anak di Kelurahan Lapulu Kota Kendari Sri Aprilianti Idris; Muhammad Sultanul Aulya; Firdayanti Firdayanti; Darmayanita Wenty; Kemal Idris Balaka; Muhammad Ilyas Y; Apriyanto Apriyanto; Bonni Rubak
BANTENESE : JURNAL PENGABDIAN MASYARAKAT Vol. 6 No. 1 (2024): Bantenese : Jurnal Pengabdian Masyarakat
Publisher : Pusat Studi Sosial dan Pengabdian Masyarakat Fisipkum Universitas Serang Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30656/ps2pm.v6i1.8764

Abstract

Infeksi kecacingan yang disebabkan oleh Soil Transmitted Helminth (STH) adalah cacing golongan nematoda usus yang penularannya melalui tanah dalam daur hidupnya. Berbagai macam cacing kelas nematoda yang diketahui yaitu cacing gelang (Ascaris Lumbricoides) cacing cambuk (Trichuris trichiura) dan cacing tambang (Ancylostoma duodenale dan Necator americanus). Penyakit cacingan sangat berpengaruh buruk bagi kesehatan, pada anak-anak cacingan akan berdampak pada gangguan dalam belajar, menurunnya kualitas kecerdasan dan berkurangnya asupan gizi yang diperoleh. Tujuan kegiatan ini adalah untuk memberikan edukasi terkait infeksi kecacingan dan mengetahui tingkat infeksi kecacingan pada anak-anak di kelurahan Lapulu Kota Kendari dengan menggunakan metode kato katz. Jenis kegiatan ini bersifat Deskriktif yaitu untuk melihat gambaran dan mendeteksi hasil pemeriksaan telur cacing nematoda usus pada anak-anak kelurahan Lapulu Kota Kendari. Sampel yang digunakan adalah feses sebanyak 40 sampel. Hasil pemeriksaan dengan metode kato katz pada 40 sampel feses anak – anak dikelurahan Lapulu Kota Kendari terdapat 1 sampel positif yaitu dengan tingkat infeksi kecacingan sangat ringat yaitu invertil sedangkan 39 sampel feses anak tidak terdapat telur cacing Nematoda Usus.
Analysis of blood calcium levels in calcium water consumers Rubak, Bonni; Umar, Ani; Reymon, Reymon; Jannah, Nanda Reski
Jurnal Ilmiah Kesehatan Sandi Husada Vol 13 No 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v13i2.1216

Abstract

Introduction: Water is a primary and basic human need. One of the chemical parameters that must be met for drinking water needs is mineral content, such as calcium and magnesium. Water hardness is a condition in which there is excessive calcium and magnesium content, which is commonly known as calcareous water. If consumed long-term, high-water hardness that exceeds normal limits can interfere with body health. Specifically, excess calcium in the body can cause hypercalcemia, hyperparathyroidism, kidney stones, and muscle tissue damage (muscle weakness). Objective: This study aims to determine blood calcium levels in individuals who consume calcareous healthy water. Methods: The type of research used is descriptive-analytical, with blood calcium level analysis carried out using the Ion Selective Electrode (ISE) method through the Electrolyte Analyzer (CBS400). Result: Based on the results of the study, it was obtained that blood calcium levels in 30 community respondents in Ranomeeto District (100%) were above the reference value, indicating high blood calcium levels. Conclusion: blood calcium levels in people who consume lime juice indicate high blood calcium levels. Consuming water with a high lime content can hurt health. Therefore, people need to consider the quality of the drinking water they drink, especially those that have a high lime content, to maintain heart and kidney health in the long term.
Korelasi Indeks Eritrosit Dan Red Cell Distribution Width (RDW) Pada Pasien Gagal Ginjal Kronik di Instalasi Hemodialisa RSUD Bahteramas Bonni Rubak; Susanti; Reymon; Sendy Ramadhany
Jurnal Analis Kesehatan Kendari Vol. 7 No. 2 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (2) Juni 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i2.349

Abstract

Chronic kidney failure (CKD) is a disease condition that progressively occurs with a slow decline in kidney function that cannot return to normal, so that in advanced stages it requires replacement therapy such as hemodialysis. One of the most common complications in patients with CKD is anemia. This anemia is usually caused by reduced production of erythropoietin hormone which causes a shortening of erythrocyte lifespan. To evaluate the characteristics of anemia in chronic kidney failure (CKD) patients, hematological examination of erythrocyte indices, including Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), and Mean Corpuscular Hemoglobin Concentration (MCHC), as well as Red Cell Distribution Width (RDW), are performed. This study aims to determine the correlation between erythrocyte indices (MCV, MCH, and MCHC) and Red Cell Distribution Width (RDW) in CKD patients undergoing hemodialysis at Bahteramas Hospital. The study was conducted descriptively analytically with accidental sampling method of 77 CKD patients. The results of statistical analysis using the chi-square test showed a significant value in the MCV examination and RDW value of 0.000 under the p value <0.05, MCH examination and RDW value found a significant value of 0.000 under the p value <0.05, and MCHC examination and RDW value found a significant value of 0.000 under the p value <0.05. This shows that there is a statistically significant relationship between erythrocyte index and RDW value in CKD patients in the Hemodialysis Installation at Bahteramas Hospital.
UJI EFEKTIVITAS EMULGEL ANTI JERAWAT EKSTRAK ETANOL DAUN JERUJU (Acanthus ilicifolius) TERHADAP Staphylococcus aureus rusli, Nirwati; Muh Azdar Setiawan; Yulianti Fauziah; Eny Nurhikmah; Esti Badia; Bonni Rubak; Riswanti Ruslan; Reymon; Isna Dwi Wulandari
Jurnal Analis Kesehatan Kendari Vol. 7 No. 2 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (2) Juni 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i2.350

Abstract

ABSTRACT The Jeruju plant is one of the true mangrove species that typically grows in coastal areas, rivers, swamps, and brackish water regions, and is used for medicinal purposes. Scientific data on Jeruju leaf (Achantus ilicifolious) extract indicate the presence of alkaloids, flavonoids, tannins, steroids, and saponins, all of which can be utilized for their antibacterial properties, particularly against the acne-causing bacterium Staphylococcus aureus. Staphylococcus aureus is known to cause skin blockages, which in turn trigger inflammation and the appearance of acne. The aim of this research was to determine whether an ethanol leaf extract emulgel of Jeruju (Achantus ilicifolious) could inhibit Staphylococcus aureus bacteria. The results of the study indicated that at a concentration of 10%, a inhibition zone of 3.8 mm was obtained, at 15% concentration it was 4.7 mm, and at 20% concentration it was 4.8 mm, categorizing the inhibition zones as weak (<5 mm).
Pengaruh Jenis Pelarut terhadap Aktivitas Antioksidan Ekstrak Daun Ubi Ungu (Ipomea batatas L.) sernita, sernita; Rubak, Boni; Srimayona, Wa Ode
Jurnal Analis Kesehatan Kendari Vol. 6 No. 2 (2024): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 6 (2) Juni 2024)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v6i2.304

Abstract

ABSTRACT Ethanol extract of purple sweet potato leaf contained secondary metabolite components, flavonoid and tannin. Flavonoids are polyphenol compounds that are widely distributed in plants as glycosides which bind to a sugar, therefore flavonoids are polar compounds. Polar solvents include methanol, ethanol, acetone and water. This research was conducted to determine the effect of extractor variation on the activity of antioxidant activity in purple potato sweet leaf extract (Ipomea batatas L.) Antioxidant activity of methanol extract, ethanol extract and acetone extract of purple sweet potato leaf was determined using DPPH method and vitamin C as a comparison with three replications. The results of the antioxidant activity determining showed that the average IC50 (Inhibitory Concentration) value of methanol extract was 52,52 mg/L; ethanol extract 30,82 mg/L; acetone extract was 9,86 mg/L and Vitamin C was 6.24 mg/L. Based on the results of One Way ANOVA and LSD analysis, the extractor variance give a significant effect on the antioxidant activity of purple sweet potato leaf extract. Keywords:Purple sweet Potatoes Leaf, Methanol Extract, Etanol Extract, Acetone Extract, DPPH. ABSTRAK Ekstrak etanol daun ubi ungu positif mengandung komponen metabolit sekunder golongan flavonoid dan tannin. Flavonoid merupakan senyawa golongan polifenol yang terdistribusi luas pada tumbuhan dalam bentuk glikosida yang berikatan dengan suatu gula, karena itu flavonoid merupakan senyawa yang bersifat polar. Pelarut yang bersifat polar diantaranya metanol, etanol, aseton dan air. Penelitian ini dilakukan untuk mengetahui pengaruh jenis pelarut terhadap aktivitas senyawa antioksidan dalam ekstrak daun ubi ungu (Ipomea batatas L.). Aktivitas antioksidan pada ekstrak metanol, ekstrak etanol dan ekstrak aseton daun ubi ungu diuji dengan menggunakan metode DPPH serta vitamin C sebagai pembanding dengan tiga kali replikasi. Hasil uji aktivitas antioksidan menunjukkan nilai IC50 (Inhibitory Concentration) rata-rata ekstrak metanol daun ubi ungu sebesar 52,52 mg/L; ekstrak etanol daun ubi ungu sebesar 30,82 mg/L; ekstrak aseton daun ubi ungu sebesar 9,86 mg/L dan pembanding Vitamin C sebesar 6,24 mg/L. Berdasarkan hasil analisis One Way ANOVA dan Uji BNT, jenis pelarut memberikan pengaruh yang signifikan terhadap aktivitas antioksidan ekstrak daun ubi ungu. Kata Kunci: Daun Ubi Ungu, Antioksidan, Ekstrak Metanol, Ekstrak Etanol, Ekstrak Aseton, DPPH
Rimpang Etlingera rubroloba A.D. Poulsen sebagai Kandidat Imunostimulator terhadap Fagositosis Makrofag dan Sel CD8 Ilyas Y., Muhammad; Reymon, Reymon; Rasak, Adriatman; Rubak, Bonni; Pascayantri, Asniar; Malik, Fadhliyah; Jabbar, Asriullah; Wahyuni, Wahyuni; Setiawan, La Ode Roni; Halik, Halik; Sahidin, Idin
Indonesian Journal of Pharmaceutical Science and Technology Vol 13, No 1 (2026)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v13i1.52621

Abstract

Etlingera rubroloba A.D. Poulsen merupakan tumbuhan yang digunakan secara tradisional oleh masyarakat Sulawesi Tenggara untuk menjaga kebugaran tubuh dan telah terbukti secara ilmiah mampu meningkatkan sistem imun bawaan melalui peningkatan ekspresi reseptor sel makrofag (CD14). Namun, pengaruhnya terhadap aktivitas fagositosis makrofag dan kadar sel limfosit T sitotoksik (CD8+) belum pernah dilaporkan. Penelitian ini bermaksud mengevaluasi ekstrak etanol rimpang E. rubroloba terhadap efek peningkatan fagositosis makrofag dan kadar CD8+ pada tikus putih (Rattus norvegicus) galur Wistar. Sebanyak 24 ekor tikus dibagi enam kelompok, yaitu kontrol normal, kontrol negatif, kontrol positif, serta kelompok ekstrak dosis 200, 300, dan 400 mg/kg BB. Ekstrak diberikan secara oral selama tujuh hari, kemudian pada hari kedelapan hewan uji diinfeksi Staphylococcus aureus secara intraperitoneal. Aktivitas fagositosis diamati secara mikroskopik, sedangkan kadar CD8+ diukur menggunakan metode ELISA. Dosis 300 mg/kg BB menghasilkan peningkatan aktivitas fagositosis tertinggi sebesar 77,25% dan kadar CD8+ tertinggi sebesar 650,71 ng/mL, dengan perbedaan bermakna dibandingkan kontrol negatif (p<0,05). Temuan ini mengindikasikan bahwa rimpang E. rubroloba berpotensi dikembangkan sebagai kandidat imunostimulator alami.
Analysis of blood calcium levels in calcium water consumers Bonni Rubak; Ani Umar; Reymon Reymon; Nanda Reski Jannah
Jurnal Ilmiah Kesehatan Sandi Husada Vol. 13 No. 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : LPPM Politeknik Sandi Karsa, South Sulawesi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Water is a primary and basic human need. One of the chemical parameters that must be met for drinking water needs is mineral content, such as calcium and magnesium. Water hardness is a condition in which there is excessive calcium and magnesium content, which is commonly known as calcareous water. High water hardness that exceeds normal limits can interfere with body health if consumed long-term. Specifically, excess calcium in the body can cause hypercalcemia, hyperparathyroidism, kidney stones, and muscle tissue damage (muscle weakness). Objective: This study aims to determine blood calcium levels in individuals who consume calcareous healthy water. Methods: The type of research used is descriptive-analytical, with blood calcium level analysis carried out using the Ion Selective Electrode (ISE) method through the Electrolyte Analyzer (CBS400). Result: Based on the results of the study, it was obtained that blood calcium levels in 30 community respondents in Ranomeeto District (100%) were above the reference value, indicating high blood calcium levels. Conclusion: blood calcium levels in people who consume lime juice indicate high blood calcium levels. Consuming water with a high lime content can hurt health. Therefore, people need to consider the quality of the drinking water they drink, especially those that have a high lime content, to maintain heart and kidney health in the long term.
Co-Authors Adriatman Rasak Ani Umar Apriyanto Apriyanto Badia, Esti Balaka, Kemal Idris Darmayanita Wenty Eny Nurhikma Fadhliyah Malik Fauziah, Yulianti Firdayanti Firdayanti Halik, Halik Ilyas Y., Muhammad Isna Dwi Wulandari Jabbar, Asriullah Jannah, Nanda Reski Muhammad Ilyas Y Muhammad Sultanul Aulya Nanda Reski Jannah Nirwati Rusli Pascayantri, Asniar Reymon, Reymon Riswanti Ruslan Sahidin Sahidin Sendy Ramadhany Sernita Setiawan, La Ode Roni Setiawan, Muhammad Azdar Sri Aprilianti Idris Srimayona, Wa Ode Susanti Susanti wahyuni wahyuni