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All Journal Open Access Health Scientific Journal Jurnal Ipteks Terapan : research of applied science and education Strada Journal of Pharmacy APMa Jurnal Pengabdian Masyarakat
Devita Riafinola
Universitas STRADA Indonesia
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Testing the Anti-Bacterial Activity of Star Gooseberry Leaves (Souropus Androgynus L) Using the Disc Diffusion Method Using the n-Hexane Fraction Against Propionic Bacterium Acnes Devita Riafinola Andaririt; Ardi Broto
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.100

Abstract

Acne vulgaris or acne, is a common inflammatory condition in the polysebaceous unit that occurs in teenagers and young adults and is characterized by comedones, papules, pustules, and nodules. One of the factors that causes acne is the Propionic bacterium acnes bacteria. One type of plant with antibacterial properties for acne is the Star Gooseberry Leaf plant (Souropus Androgynus L), which contains alkaloids, saponins, tannins, and flavonoids that act as antibacterials. Susanti (2012). This research aimed to obtain data on the antibacterial activity of the compound components contained in the n-hexane fraction of Star Gooseberry Leaves (Souropus Androgynus L) against the Propionic bacterium acnes bacteria, which can be seen from the inhibition zone. The method used was disc diffusion with three groups of control, namely (K(S), K(+), and K(-)). The test bacteria Propionic bacterium acnes, where the Control Sample consists of 4 test concentrations, namely 30 mg, 60 mg, 120 mg, and 240 mg. The positive control used two µg/disc Clindamycin, while the negative control was 2% DMSO. The results of the disc diffusion test of the ethanol fraction of Star Gooseberry Leaves (Souropus Androgynus L) using the disc diffusion method with concentrations of 30 mg/ml and 60 mg/ml did not provide an inhibition zone, the concentration of 120 mg/ml was 11.1 ± 0.10 mm, the concentration was 240 mg/ml was 14.63 ± 0.25 mm. The negative control DMSO 2% did not provide an inhibitory zone diameter, whereas the positive control Clindamycin 2 µg/disk provided an inhibition zone of 25.47 ± 0.70 mm.
Formulation and Physical Quality Evaluation of Cyperus rotundus L. Water Fraction Gel Alfara Derista Felany; Juvita Herdianty; Devita Riafinola Andaririt; Ivan Junius Mesak; Bilal Subchan
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.202

Abstract

The development of topical preparations from natural ingredients requires rigorous physical quality evaluation to ensure their safety, stability, and efficacy. This study aimed to formulate and evaluate the physical quality of a gel preparation containing the water fraction of Cyperus rotundus L. at various concentrations. The water fraction of the rhizome was formulated into gel preparations with concentrations of 5% (F1), 10% (F2), 15% (F3), and 20% (F4) using Carbopol 940 as a gelling agent. The physical quality evaluation included organoleptic tests, homogeneity, pH, spreadability, adhesion, and viscosity. The results showed that all gel formulas met the established physical quality requirements. An increase in the concentration of the water fraction significantly affected the physical characteristics of the preparation, such as a more intense color, as well as an increase in pH, adhesion, and viscosity. All formulas exhibited a pH suitable for the physiological range of the skin (5.53–6.80), good spreadability (5.49–6.77 cm), and adequate adhesion (>2 seconds). It was concluded that the nut grass rhizome water fraction gel has stable and acceptable physical characteristics, making it a potential candidate for further development as a topical preparation.
Peningkatan Pengetahuan Remaja tentang Penggunaan Bahan Alam dalam Mengatasi Asam Lambung Luluk Aniqoh Meliana Putri; Sri Rahayu Dwi Purnaningtyas; Selly Septi Fandinata; Dabyt Faizin Firzatullah; Varel Tsania Faza; Devita Riafinola Andaririt; Chinthia Devientasari; Ivan Junius Mesak
APMa Jurnal Pengabdian Masyarakat Vol. 6 No. 2: Juli 2026
Publisher : STIKES Bhakti Husada Mulia Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47575/apma.v6i2.949

Abstract

Peningkatan kasus asam lambung pada remaja dipengaruhi oleh gaya hidup tidak sehat dan rendahnya pengetahuan mengenai pencegahan serta penanganannya, sehingga kegiatan ini bertujuan meningkatkan pemahaman remaja tentang penggunaan bahan alam dalam mengatasi asam lambung. Metode yang digunakan adalah edukasi melalui penyuluhan kesehatan kepada siswa SMA dengan media presentasi, brosur, serta evaluasi menggunakan pretest dan post-test. Hasil menunjukkan adanya peningkatan signifikan pengetahuan peserta dari rata-rata 65,15% menjadi 91,51% setelah diberikan edukasi. Remaja mampu memahami penyebab, gejala, pencegahan, serta pemanfaatan bahan alami seperti jahe, kunyit, sereh, madu, dan pepaya sebagai alternatif penanganan awal. Hasil analisis statistik menggunakan uji Paired T-Test menunjukkan adanya perbedaan yang signifikan antara nilai pretest dan post-test (p<0,001), sehingga edukasi kesehatan berbasis bahan alam dapat meningkatkan pengetahuan remaja mengenai pengendalian asam lambung.
Effectiveness and Physical Quality Test of Ashitaba Leaf Extract Exfoliating Toner against Staphylococcus epidermidis and Propionibacterium acnes Luluk Aniqoh Meliana Putri; Devita Riafinola Andaririt
Open Access Health Scientific Journal Vol. 7 No. 1 (2026): February 2026
Publisher : Griya Eka Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55700/oahsj.v7i1.134

Abstract

Background: Acne (acne vulgaris) is a chronic inflammatory skin disease with a complex pathogenesis, involving the sebaceous glands and excessive colonization of acne-causing bacteria. In the modern era, the trend of using natural cosmetics is gaining momentum, not only in Indonesia but also globally. An example of a plant with great potential is Ashitaba. Ashitaba leaves have antibacterial. This study aimed to observe the physical quality test and antibacterial test of ashitaba leaf extract toner against Staphylococcus epidermidis and Propionibacterium acnes bacteria.Methods: The design in this study is an experimental method, physical quality tests include, Organoleptic tests are carried out visually, the components evaluated are the smell, shape, color and texture of the preparation, pH test and viscosity test.  analysis of data from the physical quality test of the Ashitaba leaf extract facial toner, the physical characteristics of the preparation, including organoleptic, homogeneity, viscosity, and pH, of all three formulas met the parameters.Results: The toner tested against Staphylococcus epidermidis and Propionibacterium acnes bacteria had the largest inhibition zone, namely with an extract concentration of 20%.Conclusion: The toner tested against Staphylococcus epidermidis bacteria with a 20% extract had the largest inhibition zone of 27.6 mm, while Propionibacterium acnes bacteria with a 20% extract had the largest inhibition zone of 27.9 mm
Co-Authors Adjie Wahyu Pradana Agus Wahyudi Alfara Derista Felany amalianurzahra Anggi Restyana Ardhi Broto Sumanto Ardi Broto Arif Wijayanto Bilal Subchan Candra Asih Setyaningrum, Candra Chinthia Devientasari Chinthia Devientasari Dabyt Faizin Firzatullah Ivan Junius Mesak Ivan Junius Mesak Ivan Junius Mesak Juvita Herdianty Juvita Herdianty Novi Kurniasari Poppy Martha Lowra Purnaningtyas, Sri Rahayu Dwi Putri, Luluk Aniqoh Meliana Ratna Wardani Selly Septi Fandinata Sri Rahayu Dwi P Sri Rahayu Dwi Purnaningtyas Tutus Fibri Varel Tsania Faza