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Osteochondroma: A Literature Review with Case Illustrations Firdaus, Nadine Aisyah Sultan; Aliyyu, Aisah; Zubaedi, Alisha Chaerani; Prawiro, Aurellia Wongso; Remtaya, Baiq; Rameci, Hadil Hudati Awwari; Aghni, Hasna Tazkia; Kusuma, I Gusti Ketut Artha Jaya; Ramadhan, Panji Sena; Mikailla, Romy Healthy
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10183

Abstract

Osteochondroma is the most common benign bone tumor, typically discovered during periods of skeletal growth. Although frequently asymptomatic, it may cause pain, deformity, neurovascular compression, or in rare instances undergo malignant transformation into secondary chondrosarcoma. This study presents a case-based literature review to illustrate the spectrum of clinical manifestations, diagnostic approaches, and management strategies of osteochondroma. Three representative cases were analyzed: a 52-year-old female with talar osteochondroma presenting with ankle pain and swelling; a 17-year-old male with distal femoral osteochondroma manifesting as a posterior thigh mass with minimal symptoms; and a 26-year-old female with Hereditary Multiple Exostoses (HME) who developed secondary chondrosarcoma. The comparison highlights that solitary lesions are often managed effectively with simple excision, while HME carries a higher risk of malignant transformation requiring more complex interventions, such as total hip replacement and adjuvant radiotherapy. Overall, osteochondroma generally has an excellent prognosis; however, careful evaluation and long-term monitoring are crucial, particularly in patients with HME.
Diverticulitis: A Literature Review Husnul Khotimah, Andi; Firdaus, Nadine Aisyah Sultan; Haikal, Muhammad; Wulandari, Baiq Nurhandini; Zubaedi, Alisha Chaerani; Hanifah, Hanum Retno; Prawira, I Nyoman Dio Yudha; Nurhidayati, Nurhidayati
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10317

Abstract

Diverticulitis is an inflammatory disease of the intestinal wall that often occurs in the elderly and is commonly located in the sigmoid colon. Risk factors for diverticulitis include a low-fiber diet, obesity and smoking, while physical activity and a healthy diet can lower the risk. Treatment of diverticulitis includes the use of selective antibiotics, especially in patients with complications or high risk, and surgical intervention may be required in complicated cases. The prognosis of the disease depends on age, severity, and the presence of complications, with a significant risk of recurrence in some patients. This paper aims to provide a comprehensive explanation of the definition, classification, epidemiology, etiology, risk factors, pathophysiology, clinical manifestations, management, complications, prognosis, and prevention of diverticulitis. This literature review was conducted using a literature study method, with data sources obtained from online databases such as PubMed, ScienceDirect, ProQuest, and Google Scholar.
Biomechanics of Flexion and Extension Spinal Injury: A Study of AOSpine Thoracolumbar Fracture Type B Zubaedi, Alisha Chaerani; Rachman, Amanda Azkiyah; Hardiant, Excell Defry; Mikailla, Romy Healthy; Priyanto, Bambang
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10877

Abstract

The thoracolumbar junction is highly vulnerable to injury due to its transitional biomechanics. Flexion-distraction and extension-distraction forces commonly produce AOSpine Type B injuries. To describe the biomechanics of thoracolumbar flexion and extension injuries and summarize AOSpine Type B fracture mechanisms. A narrative literature review was conducted using scientific articles, textbooks, and AOSpine guidelines focusing on thoracolumbar anatomy, biomechanics, and Type B injury mechanisms.  AOSpine Type B injuries result from tension band failure. Flexion-distraction (B1-B2) disrupts posterior structures, whereas extension-distraction (B3) causes anterior tension band failure, often influenced by spinal rigidity or high energy trauma. Understanding biomechanical mechanisms of AOSpine Type B injuries is essential for accurate classification and guiding management decisions.