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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 390 Documents

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Guillain Barre Syndrome pada Kehamilan Hermin Sabaruddin; Pribakti Budinurdjaja; Fakhrurrazy Fakhrurrazy
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Guillain-Barre Syndrome (GBS) is a clinical syndrome characterized by the presence of the complete flaksid that occurs in acute. GBS associated with autoimmune reaction that affect peripheral nerve, radix, and cranial nerve. The incidence of GBS is 1 – 2 per 100,000 people/year. The incident was followed by increased age and the increasing population of obstetrics. GBS in pregnancy ranged from 13% in the first trimester, 47% in the second trimester, and 40% in the third trimester. In this case report reported Mrs. M 27 years old with a diagnosis of G2P1A0 h. 39-40 weeks + insimanation + living single fetal Presentation Head + Inpartu kala II + GBS + Failed + Vacuum Severily Underweight (BMI = 17) + TBJ 3000 Gr. Diagnosis of GBS are enforced based on anamnesis, physical examination and complementary examinations. From a previous illness history found anamnesis the weakness of limbs beginning in 2016. A history of the use of breathing apparatus and admitted tot the ICU in the first pregnancy. Mrs. M had a history of infections before being diagnosed with GBS. On this second pregnancy patients cannot move lower extremity but upper extermity is still functioning. Physical examination result of mothers and babies in the normal range even though found in conditions of severily BMI underweight. The patient finally decided to SC (section caesaria) and applied the IUD intracaesarean GBS in pregnancy is a coincidental. GBS is rarely aggravate pregnancy, but if not quickly identified and handled can enhance the high morbidity in both mother and fetus. In acute attacks (AIDP) in pregnant women with GBS increase stress on the mother or the fetus. The stress that occurs can also stimulate the immune system to produce prostaglandins, resulting in premature birth. Patients can give birth when the gestational age is still 7 months. It was different in the second pregnancy in this case where the patient was diagnosed with chronic inflammatory demyelinating polyradiculopathy (CIDP) so that GBS did not affect the mother and the fetus.

PROFILE OF TETANUS IN CHILDREN AT PROF.KANDOU HOSPITAL 2002-2008 Ayling Sanjaya; Novie Homenta Rampengan; Tommy Homenta Rampengan
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v2i1.43

Backgrounds. Tetanus or lockjaw is an acute disease dwelling central nervous system caused by tetanoplasmin toxin produced by Clostridium tetani. Muscle spasm without consciousness disorder is distinguishing symptoms of tetanus. Tetanus in children remains as a health problem in developing countries including Indonesia.Objectives. To study the profile of tetanus in children.Methods. Retrospective review of children diagnosed as tetanus at Prof. Dr. R.D.Kandou Hospital from 2002 to 2008. The datas were analyzed descriptively.Results. There were 17 children with tetanus with age range 1-8 years, 12 males and 5 females. Seven of them had no tetanus immunization dan the rest of children with immunization never got booster immunization . Twelve children had otitis media and 5 children had untreated wound on their lower extremities as focus of infections. Period of getting wounded until symptoms appeared is approximately 3 days to 1 month.Common symptoms are trismus, convulsion, fever, opistotonus in all children. Complications such as bronchopneumonia occurred in 5 children, 4 children with severe tetanus and complications died in 19 hours to 18 days of treatment and the rest of 8 children had no complications.Conclusions. Tetanus in children remains as health problem. Promoting prevention awareness in community and health providers is very important to decrease tetanus mortality and morbidity in children.

Cover Volume 9 Nomer 2 Edisi September 2020 Putu Oky ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

ANTHRAX in INDONESIA Asih Rahayu
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

Anthrax is a zoonosis disease caused by Bacillus anthracis bacteria. This bacteria is able to produce an endospora that lasts for decades inside the soil and thus becomes an infection source (endemic areas), causing difficulties to eradicate this disease in Indonesia. This disease mainly infects cattle such as cows, goats, horses, and pigs in some cases. It can also infect humans through three ways which is per cutaneous, per oral, and per inhalation. The clinical manifestations in humans are malignant pustule, hematemesis, pneumonia hemorrhagic or meningitis. The success of eradicating anthrax from humans fully depends on the eradication of this disease from the animals.

Pengaruh Pemberian Curcumin Terhadap Perbaikan Fungsi Hepar Tikus Putih (Rattus Novergicus) yang diinduksi Parasetamol Dosis Tinggi Yolanda Esperanza; Sulistiana Prabowo; Fitri Handajani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 2 (2021): SEPTEMBER 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Paracetamol has analgesic properties comparable to NSAIDs, but paracetamol have minimal side effects. Paracetamol is metabolized via sulfation and glucuronidation conjugation which is then excreted in the urine. A small part of the paracetamol has been changed to NAPQI. NAPQI will be detoxified by gluthathione. In high doses, there in an increase in NAPQI and a decrease in glutathione levels that results in oxidative stress and liver cell necrosis. Curcumin is often used as a traditional medicine to treat liver disease where it contains phenolic groups capable to scavenge free radicals. Curcumin extract can improve cellular responses to oxidative stress such as increasing the expression of Nrf2, SOD, and gluthathione. The purpose of this research was to know the effect of curcumin on the improvement of liver function in white rats (Rattus novergicus) induced by high dose paracetamol. The design of this research was a descriptive research using literature studies from at least 15 international journals indexed by Scimago or national journals indexed by Sinta published in 2015-2020. Based on the journals used in this research, giving curcumin at a dose of 200 mg/kg BW/day for 2 weeks was effective in significantly increasing gluthathione levels in rats receiving high dose paracetamol. Giving curcumin at a dose of 100 mg/kg BW/day for 7 days can reduce AST and ALT activity in rats receiving high dose paracetamol, but the dose of curcumin that was more effective in reducing AST and ALT activity was 200 mg/kg BW/day for 2 weeks. This is because of curcumin which functions as a hepatoprotector that bind directly to the toxic metabolite of paracetamol, thereby reducing the use of glutathione and quench free radicals, so that oxidative stress in the liver decreased and gluthathione levels increased, AST and ALT activity decreased.

PENGARUH SUHU DAN WAKTU PENYIMPANAN TERHADAP VITAMIN C DALAM JAMBU BIJI (Psidium Guajava) masfufatun masfufatun; Widaningsih Widaningsih; Nur Kumala Indahsari; Tri Rahayuningsih
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2010): Edisi Januari 2010
Publisher : Universitas Wijaya Kusuma Surabaya

The purpose of this study was to determine whether there is influence of temperature and storage time on vitamin C content in guava. This study is an experimental research menggunkan Completely Randomized Design (CRD) with two factors and two repetitions. Of the two factors were obtained eight combinations of treatments. Each - each treatment was repeated twice, in order to obtain 16 replicates. The parameters used were vitamin C content in guava. Guava that has been stored in a specific time and temperature peel and blend until homogeneous to obtain slurry. Furthermore slurry disentrifuge guava and filtered. Filtrate obtained its vitamin C content determined by titration method Iodometri. Data obtained with ANOVA dinalisis. If there is any real difference followed by Least Significant difference test (LSD). Results showed that storage time and temperature affect the levels of vitamin C in guava fruit ripe. The longer the storage time and the higher the temperature the lower the vitamin C content. Vitamin C content in guava stored at room temperature for 10 days decreased by 46.35% and the cold temperature is only 39%.

Pengembangan Potensi Universitas Wijaya Kusuma Surabaya Menjadi Universitas Riset melalui Pembentukan Kelompok Riset – Tinjauan Literatur Sri Lestari Utami
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 1 (2022): MARET 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Various universities founded as research universities in the 19th century conducted research that assisted the progress of various fields in European and American countries. Research universities/research-based universities are characterized by the presence of research activities in the Tri Dharma of Higher Education. Several universities in Indonesia have declared themselves to be research universities, and others are in the process of doing so. Research universities must meet various indicators, all of which stem from research activities. The purpose of this paper is to investigate and compare the readiness of Universitas Wijaya Kusuma Surabaya (UWKS) to become a research university. One method for achieving these goals is the formation of research groups. This essay uses a narrative review design. A UWKS is a private university founded in 1981 in Surabaya, East Java. A long track record of research since its establishment is sufficient provision to prepare it to become a research university. This is also supported by the university's academic community and the foundation that manages it, when viewed from the vision, mission, and objectives. The formation of various research groups could be the start of the development of research universities. They will enable lecturers to produce targeted outputs as indicators of research performance, such as research groups for early detection of chronic degenerative diseases based on specific Indonesian polymorphisms. The paper's conclusion was that UWKS has the potential to become a research university based on its track record. The formation of many research groups is one way to accomplish this.

Pola Pertumbuhan Pseudomonas sp. dengan Menggunakan Variasi Konsentrasi D-glukosa dalam Media Pertumbuhan terhadap Waktu Inkubasi Agusniar Furkani Listyawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 2 (2016): Edisi September 2016
Publisher : Universitas Wijaya Kusuma Surabaya

This study was to determine the growth pattern of Pseudomonas sp. by administering various concentration of D-glucose to the growth medium and to see its effect on various incubation times. Addition of D-Glucose in the growth medium as a source of bacterial carbon that can support the cell growth process. The results showed that, the use of D-glucose with various concentration in growth media of Pseudomonas sp. affect the formation of bacterial cell growth patterns. This study showed that Pseudomonas sp. using D-glucose substrate for it’s cell growth. While the longer incubation time didn’t had effect for the cell growth pattern due to the ability of bacteria in consuming substrates that are added to the growth medium.

PENATALAKSANAAN PADA DIABETIC PERIPHERAL NEUROPATHIC PAIN (DPNP) Herni Suprapti
Jurnal Ilmiah Kedokteran Wijaya Kusuma No 1 (2011): Edisi Juli 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v0i1.2145

Penyebab diabetic peripheral neuropathic pain (DPNP) masih belum diketahui, dan nyeri yang dirasakandapat sangat hebat sehingga mengganggu aktivitas. DPNP tidak dapat disembuhkan, tetapi untukmemperbaiki kualitas hidup, perlu diberikan terapi untuk mengontrol nyeri, yaitu dengan memberikanobat topikal, obat oral, serta tindakan non-farmakologi lain (akupunktur dan transcutaneous nervestimulation). Diabetic peripheral neuropathic pain (DPNP) mengenai sekitar 10% sampai 20% dari 20 juta pendudukAmerika yang menderita diabetes mellitus (DM) (1,2).

Ekstrak Bawang Putih Siung Tunggal terhadap Aktivitas Enzim Lipoprotein Lipase pada Tikus Hiperkolesterol Juliana Veronica Brouwer
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 2 (2018): Edisi September 2018
Publisher : Universitas Wijaya Kusuma Surabaya

Hiperkolesterolemia merupakan suatu keadaan dimana kadar kolesterol didalam darah mengalami peningkatan diatas angka rata-rata nilai normal yang telah di tetapkan secara standar. Terapi herbal tradisional merupakan terapi alternatif yang dapat digunakan untuk mencegah dan menurunkan kadar trigliserida di dalam darah. Salah satu pilihan terapi yang digunakan adalah bawang putih siung tunggal (Allium Sativum Linn.). Bawang putih siung tunggal memiliki kandungan antioksidan yang kuat yaitu flavonoid, apabila dengan rutin mengkonsumsinya dapat menurunkan kadar trigliserida didalam darah sehingga resiko penyakit degeneratif dapat dikurangi. Flavonoid adalah senyawa golongan polifenol. flavonoid memiliki kemampuan sebagai antikolesterol. Flavonoid bekerja pada banyak enzim dalam pembentukan kolesterol atau trigliserida, salah satunya adalah enzim lipoprotein lipase. Sehingga, apabila aktivitas enzim lipoprotein lipase meningkat, maka proses pembentukan trigliserida melalui mekanisme jalur eksogen di pembuluh darah terhambat sehingga kadar trigliserida dapat menurun. Penelitian ini menggunakan jenis penelitian eksperimental laboratorium dengan design Pre test- Post test Controlled. Menggunakan 5 kelompok dengan masing-masing kelompok menggunakan 5 ekor tikus. uji Paired T-Test menunjukkan bahwa terdapat perbedaan aktivitas enzim lipoprotein lipase dengan nilai signifikansi (p < 0.05) sedangkan pada uji Manova, nilai signifikansi yang didapatkan adalah (p. < 0.05). Berdasarkan hasil penelitian, dapat disimpulkan bahwa pemberian ekstrak bawang putih siung tunggal dapat meningkatkan aktivitas dari enzim lipoprotein lipase.

Page 23 of 39 | Total Record : 390

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