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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 390 Documents

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Induction of interleukin-6 trigger an apoptosis through IL-17 and stat3 pathway that alleviated by phycocyanin treatment Elizabeth Haryanti; Harry K Gondo
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 2 (2016): Edisi September 2016
Publisher : Universitas Wijaya Kusuma Surabaya

This study was to analyze the optimum dose of IL-6 induction in pregnant rats that could trigger an increase in mean arterial pressure and protein as two symptoms of preeclampsia. A total of 25 pregnant rats was divided into 5 groups, including pregnant rats the control group (without induction of IL-6), a group of pregnant rats were given an induction in IL-6 doses of 1.25 ng/day, a group of pregnant rats given doses of IL-6 induction 2.5 ng/day, a group of pregnant rats were given an induction of IL-6 doses of 5 ng/day, and groups of pregnant rats were given an induction in IL-6 doses of 10 ng/day. Induction of IL-6 was performed on the tenth day of gestation for 5 days. The expression of caspase-3, IL-17, and STAT3 were analyzed by confocal laser scanning microscopy. The expression of caspase-3, IL-17 and STAT3 was significantly higher in preeclampsia group than the control group (p<0.05). The expression of caspase-3 decreased significantly in all groups were treated by phycocyanin compared to the preeclamptic group (p<0.05), but has not been able to reach expression comparable to the control group (p<0.05). Expression of IL-17 decreased significantly in the group given the two highest doses of phycocyanin compared to the preeclampsia group (p<0.05). STAT3 expression decreased significantly in all groups were treatedby phycocyanin compared to the preeclamptic group (p<0.05), reached expression comparable to the control group in the group received phycocyanin at doses of 10 and 20 ng (p> 0.05). In conclusion, IL-6 on pregnant rats were able to increase apoptosis through IL-17 and STAT pathway. Inhibition of apoptosis due to phycoyanin treatment not only involve the formation of IL-17, this data is found in phycocyanin doses of 10 and 20 ng.

PEMERIKSAAN MIKROBIOLOGIS FESES Akhmad Sudibya
Jurnal Ilmiah Kedokteran Wijaya Kusuma No 1 (2011): Edisi Juli 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Ada banyak metode pada pemeriksaan mikrobiologi tinja. Metode mencakup pemeriksaan mikroskopis,kultur p ada media mikrobiologi, pemeriksaan imunologi, pemeriksaan mikrobiologi molekul, dan ujisensitivitas antibiotik. Metode yang digunakan tergantung pada mikroba yang diduga sebagai penyebabpenyakit tertentu.

Peritoneal Shunt Extraction in Children Using Laparoscopy: A Case Report Arif Kusumo Rahardjo; Yusuf Hermawan; Vita Dwi Wijayanti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Laparoscopy is one way to perform various simple procedures or surgeries in the abdominal cavity. Laparoscopy can be useful in the management of ventriculo-peritoneal shunt (VP Shunt) fractures. The peritoneal component of the shunt remaining in the abdominal cavity can be removed using laparoscopy. A pediatric patient with hydrocephalus with a history of VP Shunt insertion 5 years ago, came with complaints of weakness, vomiting and difficulty eating. Physical examination revealed the presence of edema in the chamber area. A CT scan of the head and plain abdominal radiographs were performed. The diagnosis was made as a shunt fracture, with the peritoneal component of the shunt remaining in the abdominal cavity. The patient received treatment in the form of a revised VP shunt and peritoneal shunt extraction using standard laparoscopy which is commonly used for adult patients. The patient's condition improved after the procedure. Peritoneal shunt extraction in cases of VP shunt fracture can be safely performed using laparoscopy. If there are limited tools, this procedure can still be performed on children using standard laparoscopy which is usually used for adult patients. Authors report this case due to no previous report in Mojokerto area were known.

Ekspresi Protein P53 Mutan pada melanoma maligna dan Nevus melanositik Lusiani Tjandra
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2011): Volume II, Nomor 1, Januari 2011
Publisher : Universitas Wijaya Kusuma Surabaya

melanoma maligna merupakan tumor ganas el melanosa dengan pertumbuhan agresif dan resisten terhadap terapi konvensional.

Uji Widal (Widal Test) Akhmad Sudibya
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

Widal Test is one of the application of diagnostic immunology in the diagnosis of typhoid fever. Widal Test must be taught at the school of medicine although some physicians opines that this test is quite obsolete. In real life there are stillmany physicians in developing countries who consider this test as very instrumental in the diagnosis of typhoid fever.

Korelasi Antara Immature Granulocyte dan Delta He Sebagai Penanda Inflamasi Pada Penderita Dengan Lekositosis Novina Aryanti; Juli Soemarsono
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 2 (2016): Edisi September 2016
Publisher : Universitas Wijaya Kusuma Surabaya

Immature Granulocytes are considered as an inflammation marker. Recently Delta He is suspected to be a novel marker of inflammation. The aim of this study was to know the correlation of Immature Granulocytes and Delta He as inflammation marker in patients with lecocytosis. This research used whole blood-EDTA samples from 50 lecocytosis patients in the Dr. Soetomo Hospital Surabaya from 10 until 17 December, 2011 were studied Immature granulocytes and Delta He were examined by Flowcytometry (Sysmex XE 2000i). Analysis of the results was performed by Pearson product moment. Mean result of Immature Granulocytes and Delta He from 50 patients with lecocytosis was 0.37 x 103/µL and 3.03 pg. According to Pearson analysis test there was a correlation between Immature Granulocytes and Delta He (r = 0.26), but this was not significant (p > 0.05). Inflammation induced cytokine release and rise hepcidin, the result was decrement of ferroportin from duodenum and macrophage so the iron supply to erythropoetic precursor decrease, and the hemoglobin synthesis (Ret He) decrease. The rise of Immature Granulocytes were not happened in all lecocytosis patients, it were not certain suffered sepsis. There was no significant correlation between Immature Granulocytes and Delta He in patients with lecocytosis. A further research with more samples to determine that Delta He can be used as an inflammation marker is needed

Hubungan antara Perilaku Merokok dengan Timbulnya Kalkulus Gigi pada Mahasiswa Fakultas Kedokteran Di Surabaya Fauzia Wulandari Ruslan; Wahyuni Dyah Parmasari
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 1 (2022): MARET 2022
Publisher : Universitas Wijaya Kusuma Surabaya

This study generally aims to prove the emergence of dental calculus associated with smoking behavior in surabaya medical students. This smoking behavior includes smoking duration, number of cigarettes and smoking habits. Specifically for Analyzing smoking behavior in Medical students and analyzing dental health with indicators of the presence of dental calculus in Wijaya Kusuma University Surabaya students. This research is an experimental field research with an quantitative analytical approach to examine the symptoms of smoking behavior using design observational case control. The determination of sample, which means that the sample size for the case group is as large as the control group sample(1:1). In this study were 44 samples, namely 22 case group samples and 22 control group samples. From the results of data collection regarding smoking behavior were tested with non-parametric statistical inferential tests with the Spearman correlation test with significance value (r =0,05). The results of the study are of 100% of respondents who have mild smoking habits related to calculus in good condition as many as 10 people (45,5%). While the respondents had the habit of smoking related to calculus in moderate conditions as many as 12 people (54,5%) and there were no respondents in poor calculus conditions. The conclusion of the study showed that there was a relationship between smoking behavior and the incidence of dental calculus of active medical students at the medical faculty in Surabaya with a p-value of 0,025 less than 0,05. So it can be concluded that there is a relationship between smoking behavior and the formation of dental calculus.

Pharmacogenomics Statins: Biomarkers for Clinical Prediction Herni Suprapti
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 1 (2018): edisi Maret 2018
Publisher : Universitas Wijaya Kusuma Surabaya

Statins are the most widely prescribed drug for hyperlipidemic therapy and for the prevention of Cardiovascular disease. But although statins are very effective for the prevention of atherosclerosis, there are still patients with CVD. In this case, it is thought to be the influence of genetic factors. There is a static gene link to statin dose required for therapy, but there are still no relevant pharmacogenomic tests for statin therapy guidelines. This article describes basic pharmacogenomic terminology, genes (CETP, HMGCR, SLCO1B1, ABCB1, and CYP3A4 / 5), and progression of statin pharmacogenomic biomarkers for predicted therapeutic outcomes.

Aedes aegypti sebagai vector demam berdarah dengue Kartika Ishartadiati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2011): Volume II, Nomor 1, Januari 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Aedes aegypti adalah nyamuk yang termasuk dalam subfamiliculicinae, famili culicidae ordo Diptera, kelas Insecta.

Vaksin Human Papiloma Virus (HPV) untuk Pencegahan Kanker Serviks Uteri – Harry Kurniawan Gondo
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 3 (2011): Volume Edisi Khusus Desember 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Kanker serviks merupakan penyakit keganasan fatal yang dapat dicegah. Penyebab kanker serviks adalah human papillomavirus (HPV) onkogenik risiko tinggi, terutama HPV-16 dan 18.

Page 22 of 39 | Total Record : 390

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Dukuh Kupang XXV/54 Surabaya, Medical Faculty University of Wijaya Kusuma Surabaya, Building C, 2nd Floor C216.

Location
Kota surabaya,

Jawa timur

INDONESIA