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Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)

Galenika
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Published by Universitas Tadulako

ISSN : 24427284 EISSN : 24428744 DOI : https://doi.org/10.22487/j24428744

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (E-ISSN: 2442-8744) (p-ISSN: 2442-7284), is an open access journal (print and e-journal) focusing on the scientific works in the field of Pharmacy and Pharmaceutical Science. The articles of this journal are published every six months, that is March and October (2 issues per year). This journal is developed by Department of Pharmacy, Faculty of Mathematics and Natural Science, Tadulako University and has been identified in Crossref with the DOI Number : 10.22487/j24428744. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) has been accredited by Kemenristekdikti as Sinta 3 starting from Volume 5 No 1 2019.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 241 Documents

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ANALISIS PENGARUH KEPUASAN PASIEN TERHADAP KUALITAS PELAYANAN RESEP DI APOTEK INSTALASI FARMASI BADAN RUMAH SAKIT DAERAH LUWUK KABUPATEN BANGGAI Dyah Nurfitri Maharani; Alwiyah Mukaddas; Indriani Indriani
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Pharmacy is one place of the pharmaceutical care with aims to practice pharmacy by pharmacists and pharmaceutical supply distribution to the public. One of the indicators use to evaluate the quality of care in pharmacies was to measure the level of customer satisfaction.This research is aimedto find out the impact of patient satisfaction towards the quality of prescription service in dispensary of pharmacy installation in Public Hospital of Luwuk, Banggai regency which is related with five dimension of quality service, which are; tangible, reliability, responsiveness, assurance and empathy. This research was conducted used sampling method called accidental sampling using questioner with likert scale. The data was analyzed using doubled linear regression method with the total of 110 respondent. The result from these respondent showed tangible, reliability, responsiveness, Assurance and empathyvariablewhich significantly affected the satisfaction of patient, with significance score of 0,000 (P value< 0,05). Determination coefficient resulted is 0,482 which mean that the satisfaction level of patient towards the five variables is 48,2%.

PROFIL PENGGUNAAN OBAT PADA PASIEN GOUT DAN HIPERURISEMIA DI RSU ANUTAPURA PALU Nur Fadhilatu Rahmah; Alwiyah Mukaddas; Safarudin Safarudin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Gout is a type of inflammatory arthritis triggered by the crystallization of uric acid within the joints and is often associated with hyperuricemia. Hyperuricemia is a condition with high blood uric acid levels (above normal). This study aimed to describe drug use profile of gout and hyperuricemia inpatients in Anutapura Hospital, Palu. This is a descriptive study of which samples taken retrospectively. The result showed that the characteristic of 32 inpatients are as follows : most (71.86%) of them are male, 71.86% aged 18-59 years old, 21.86% had high school educational degree, and 21.86% are civil servants. As many as 32.18% of the patients had pain clinical manifestation, 93.75% were diagnosed with gout and 90.63% had high uric acid levels. Patients with amount variation of 5 to 8 drugs were 78.13% dominated by oral anti-inflamatory class of drug therapy (46.3%), with oral NSAIDs as much as 17.71% such as meloxicam (9.71%). Most patients got tablets (50%) and the drugs were found 71.43% in oral route of administration. Keywords : Gout, Hyperuricemia, Anti-inflamatory, NSAIDs.

STUDI RETROSPEKTIF PENGGUNAAN TRIHEXYFENIDIL PADA PASIEN SKIZOFRENIA RAWAT INAP YANG MENDAPAT TERAPI ANTIPSKOTIK DI RUMAH SAKIT JIWA SAMBANG LIHUM Anggie Rahaya; Noor Cahaya
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Trihexyphenidyl (THP) is used to treat symptoms of Parkinson's disease or involuntary movements due to the side effects of certain psychiatric drugs. It can also decrease other side effects such as muscle stiffness/rigidity (extrapyramidal syndrome or EPS). EPS were an unavoidable consequence of effective antipsychotic therapy. EPS reduce beneficial effects of antipsychotic treatment on the negative, cognitive, and mood symptom domains, while increasing the risk of tardive dyskinesia and reducing compliance. The purpose of this research was to analyze the percentage use of THP and the pattern of THP usage on schizophrenia patient which treated at Sambang Lihum Hospital. This retrospective observational study was conducted at an inpatient Sambang Lihum Hospital. This research were conducted to 264 medical records of patients period January 2013 to December 2013 which receive antipsychotics medication. Data were analyzed by univariate analysis. The result showed 94.32% (n=264) received THP. This research has shown the pattern of THP usage in Sambang Lihum Hospital which was to give THP directly to patients without EPS examination is 96.79% (n=249) and there are 15.66% (n=249) patients evaluated after 14 days after THP administered. Key Words: Schizophrenia, Trihexyphenidyl, EPS

PRODUKSI PROTEIN SEL TUNGGAL DARI KULTUR Rhizopus oryzae DENGAN MEDIUM LIMBAH CAIR TAHU Leny Maryana; Syariful Anam; Arsa Wahyu Nugrahani
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Tofu wastewater is the origination of tofu’s production process that can degrade the quality of the environment if not handled properly. Another impact of this waste is the potential attack that could evoke the diseases such as diarrhea, skin diseases, and other illnesses for people who use the stream flow that has been polluted by this wastewater. However, the high-carbohydrate and protein of this waste may allow it to be used more as a microbial growth substrate to produce a Single-cell Protein. The purpose of this study is to determine the optimum incubation time and the highest protein content of Rhizopus oryzae in the medium of tofu wastewater based on the calculation of protein content percentage and the analysis of cell dry mass. And to know the optimum pH growth with the variation of pH growth which is about 4, 5, and 6. The calculation is performed in accordance with the fermentation time at 24, 48, and 72 hours. Total protein content calculated by the Kjeldahl method. The results showed the highest protein content obtained in the incubation period to 48 hours with an average percent of protein about 0.47%, 0.47%, 0.46% and a mass of cell with an average value of 0.77%, 0, 84% and 0.91%. The optimum pH of Rhizopus oryzae growth in the medium of tofu wastewater is about 5 pH. It can be concluded that the wastewater of tofu potentially used as a growth substrate of Rhizopus oryzae. Keywords: Wastewater of Tofu, Single-cell Protein, Rhizopus oryzae.

AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BAWANG MERAH (Allium cepa L.) TERHADAP BAKTERI Staphylococcus aureus Misna Misna; Khusnul Diana
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

One of the plants tat used in medicine is garlic (Allium cepa L.). In addition as medicinal traditional plant, garlic is used as food spice. Garlic utillizated for the root only, and the skin which is rich with fibrous and flavonoid is wasted. This research aim is to know if the garlic skin have antibacterial activity against Staphylococcus aureus. Garlic skin made into extract with maseration methode using 96% ethanol. Antibacterial activity test with hollow diffusion methode. Te parameter used are inhibition zone created. Variation of concentration are 5%b/v, 10%b/v, 20%b/v, 40%b/v, 60%b/v, 80%b/v. Activity test made with extract added in the hole in the Staphylococcus aureus media, then incubated at temperature 370C 24 hours. The inhibition zone 5%, 10%, 20%, 40%, 60%, and 80% extract respectively were 7,00mm, 8,30mm, 9,60mm, 11,00mm, 12,33m and 14,33mm

GEL ANTI JERAWAT EKSTRAK DAUN BUTA-BUTA (Excoecaria agallocha L.) DAN PENGUJIAN ANTIBAKTERI Staphylococcus epidermidis Ika Olivia Borman; Yusriadi Yusriadi; Evi Sulastri
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

Buta-Buta (Excoecaria agallocha L.) leaf is a type of mangrove plants that has antibacterial activity againtsbacteriacausing acne, Staphylococcus epidermidis,. This study aims to formulate buta-buta leaf extract with the concentration of 12.5 % into anti-acne gel using two gels, namely HPMC 8% (Formula 1) and Carbopol 940 2%(Formula 2). Antibacterial activity test was carried out by agar diffusion method using well. The stability and antibacterial activity data during 28 days were analyzed statistically using unpaired t-student with a degree of confidence of 95% (α = 0.05). The evaluation results of anti-acne gel form of buta-buta leaf extract in Formula 2 showedbetter characteristics than Formula 1, which include organoleptic examination, homogenity, pH and viscosity during 28 days. The antibacterial test showed the diameter of inhibition zone of Formula 2 is 11.03 mm ±0,01. The statistic analysis showed a significant difference between Formula 2 with a positive control (klindamisin gel).

FORMULASI TABLET EKSTRAK DAUN SAMBILOTO (Andrographis paniculata N.) SECARA KEMPA LANGSUNG DENGAN KOMBINASI MANITOL – SORBITOL SEBAGAI BAHAN PENGISI Lutfiana Kusumawati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

It has been conducted research about Tablets Formulation of Creat (Andrographis paniculata N.) Leaves Extract in Directly Compressed with Combination of Manitol-Sorbitol as Filler Materials. The result of test shows that every formula fulfills test conditions of quality for uniformity of weight, brittleness, size measure and hardness, such as those which qualified by Farmacope Indonesia and other monographs. Statistical test using Ansira (Variance Design Analysis) indicates that usage of filler materials combinations mannitol – sorbitol for formula I, II and III respectively 50% : 50%, 75% : 25% dan 25% : 75%, yield no significant effect for physical quality tablet

STUDI ETNOFARMASI TUMBUHAN BERKHASIAT OBAT PADA SUKU BUTON DI KECAMATAN BINONGKO, KABUPATEN WAKATOBI, SULAWESI TENGGARA Wa Ode Irma Indrayangingsih; Nurlina Ibrahim; Syariful Anam
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

Herbal plant ethno pharmacy study in Butonse has been coducted from January to april2014 in Binongko Sub-districtm Wakatobi Regency of South East Sulawesi. This research aimed tofind out various species and plant organs used, kinds of diseases healed, and the way to use the herbalplants by Butonese in Binongko Sub-district. This was a descripive research using qualitativemethod.The sample was taken through snowball technique with 17 informans by using questiomnaire.Based on the research result, it was obtained 53 species of plants and divided into 35 families thatused as medicine.The most used plants were family of Euphorbiaceae of 6 species. It was found 3kinds of unique plants used such as tali putri, daun picah, and kayu kuda. The organs used were leaf,fruit, stem, tuber, root, rhozome. Latex, flower, stem skin, and wood skin. The most used plant’sorgan was the leaves of 56%. The wey is by boiling, pounding, chewing, squeezing, slicing, smearing,burning, dropping, soaking, consuming directly, gratting, attachng, and having smoke. The most wayused is by boiling and pounding for 34% each.

STUDI ETNOFARMASI TUMBUHAN BERKHASIAT OBAT PADA SUKU KAILI LEDO DI KABUPATEN SIGI, PROVINSI SULAWESI TENGAH Ian Dianto; Syariful Anam; Akhmad Khumaidi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

Ethnomedicinal study on LedoKaili tribe has been conducted from January to April 2015 in Sigi Regency, Central Sulawesi. This study aims to know and to inventory the various species of plants, their parts, and ways of utilization used to treat any types of disease and how the by the tribe. This research is descriptive using qualitative methods and snowball sampling technique through open-ended interviews to 10 informants by using questionnaire. Based on the study results, plants used as medicine were known as many as 86 species coming from 37 familia in which four species have notbeen identified yet. The most widely used plants are from familia Zingiberaceae (8 species). Plant parts used include leaf, stem, fruit, root, rhizome, tuber, herb, bark, sap, and flower. Leafisthe part of the plant used with the highest percentage (53%). Local people use medicinal plants for purposes of chronic, infectious, and non-infectious diseases. Besides being able to treat people's illnesses,the plants were also used for body health care as well as dietary supplements. Ways of processing medicinal plants is done by boiling, crushing, squeezing, shredding and soaking. The most widely is boiled with percentage of 60%. As for how to use medicinal plants, the people use them in ways of drinking, eating, rubbing, dropping, and tapping/attaching. Drinking is the most usual way to use them with a percentage of 74%

STUDI ETNOFARMASI SUKU DONDO KECAMATAN DONDO KABUPATEN TOLITOLI SULAWESI TENGAH Mohammad Fajrin; Nurlina Ibrahim; Arsa Wahyu Nugrahani
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

This study aims to inventory and to record plants and their parts used as medicine by Dondo Tribe in Dondo Subdistrict, Tolitoli Regency, Central Sulawesi. This research is a descriptive study using qualitative methods and snowball sampling technique through open-ended interviews to 4 informants using questionnaire. The results showed that 56 plant species divided into 32 familia were used as medicine. The most widely used plant was from Euphorbiaceae family as much as 11%. Parts of plant which were used included leaf, petiole, stem, bark, flower, fruit, seed, rhizomes, tuber, and herb. Part of plant widely used was the leaf with percentage of utilization as much as 62%. The people of Dondo Tribe in Tolitoli District use the plants for treatment of illness, recovery, and maintenance of health. The methods of processing included decocting, mashing, roasting, burning, squeezing, and brewing the parts of the plant. The ways of using included drinking, eating, chewing, smearing, dropping, affixing/compressing, attaching, and rubbing the plant preparations on the sore spot as well as inhaling the fumes, and mixing it with water for bathing

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Contact Name
Muhammad Sulaiman Zubair

Contact Email
sulaiman_zubair80@yahoo.co.id

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+6285242083654

Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com

Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location
Kota palu,

Sulawesi tengah

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Muhammad Sulaiman Zubair

Contact Email sulaiman_zubair80@yahoo.co.id

Phone +6285242083654

Journal Mail Official jurnalgalenika.farmasiuntad@gmail.com

Editorial Address Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location Kota palu, Sulawesi tengah INDONESIA

Abstract

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Abstract

Contact Name
Muhammad Sulaiman Zubair

Contact Email
sulaiman_zubair80@yahoo.co.id

Phone
+6285242083654

Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com

Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako

Location
Kota palu,

Sulawesi tengah

INDONESIA