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<![CDATA[Multiple Sclerosis Relapsing Remitting Progressive Type ]]>
<![CDATA[Nora Fitri]]>;
<![CDATA[Basjiruddin Ahmad]]>;
<![CDATA[Yuliarni Syafrita]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v14i2.2208
<![CDATA[Multiple sclerosis (MS) is the most common neurologic demyelinating disease in high-income countries. The causes of MS is multifactorial involve genetics and the environment in which immune cell infiltration occurs across the blood-brain barrier, causing inflammation, demyelination, gliosis, and neuroaxonal degeneration in the substantia grisea in the central nervous system. A 23-year-old female patient was treated with four limbs weakened since 2 weeks ago accompanied by blurred vision, pain, cramps and stiffness in the back muscles and legs. The patient has experienced the same complaint before. Clinical findings reveal lhermitte sign, atrophy papillae, and tetraparese. On thoracic vertebral MRI examination without contrast and brain MRI with contrast obtained multiple sclerosis lesions. Patients receive steroid and antidepressant therapy. MS needs to be studied further because this number of cases began to emerge. ]]>
<![CDATA[Analyzing Parental Age to Determine Types of Cleft in Hayandra Peduli Foundation Patient, Indonesia ]]>
<![CDATA[Karina Karina]]>;
<![CDATA[Fransisca Fransisca]]>;
<![CDATA[Kevin Leonard Suryadinata]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v14i2.2244
<![CDATA[Cleft lip and palate are complex and known to have multifactorial risk factors with a prevalence of 0.2% in Indonesia. Also, there is no specific data about parental age-related to types of a cleft in Indonesia. This study aims to analyze parental age-related to types of cleft in patients treated by Hayandra Peduli Foundation, Indonesia. The data was collected from 2014 to 2018 from social service held by Hayandra Peduli Foundation. The data collected primarily, and 604 subjects were obtained. The results showed that 81.5% of patients were 0-5 of age, with patients' distribution were 356 male patients and 248 female patients. There was no significant correlation between maternal age and each type of cleft. Furthermore, there was no correlation between paternal age and types of cleft based on maternal group age. For young and ideal maternal group age, their p-value showed no significant correlation (p-value 0.393 for young maternal age and 0.941 for ideal maternal age). Surprisingly, the old maternal group age shows significant results, with a p-value of 0.045. In conclusion, we found that cleft palate will occur in infants born from an aging mother (>35 years old). ]]>
<![CDATA[Analysis of Reticulocyte Hemoglobin Equivalent Levels in Patients with Chronic Kidney Disease Stage IV and V ]]>
<![CDATA[Agri Febria Sari]]>;
<![CDATA[Rikarni Rikarni]]>;
<![CDATA[Deswita Sari]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2718
<![CDATA[Reticulocyte hemoglobin equivalent (RET-He) represents hemoglobin content in reticulocyte. Reticulocyte hemoglobin equivalent test can be used to asses iron status of chronic kidney disease (CKD). Iron deficiency happens in 40% CKD and could lead to anemia manifestation. Level of RET-He gives real-time assesment of iron availability for hemoglobin production and the level will getting lower when iron storage for erythropoiesis decreasing. Reticulocyte hemoglobin equivalent is more stabil than feritin and transferin saturation in assessing iron status. Aim of this study is to determine RET-He level in patients with CKD stage IV and V. This study is a cross sectional descripstive study. Subjects were 96 CKD stage IV and V patients that met inclusion and exclusion criterias. Subjects conducted blood tests at Central Laboratory Installation Dr. M. Djamil Hospital Padang from July to September 2020. Examination of RET-He level was analyzed by Sysmex XN-1000 flowcytometry fluorescense method. Data was presented in frequency distribution table. The RET-He level below cutoff (<29,2 pg) indicates the need for iron suplementation therapy for CKD stage IV and V patients. Samples with RET-He level below cutoff were 48 (50%) and 48 (50%) were above cutoff.]]>
<![CDATA[Overview of Blood Stocks and Demand During the COVID-19 Pandemic in Blood Donation Unit PMI Sleman Yogyakarta ]]>
<![CDATA[Novita Widy Astuti]]>;
<![CDATA[Nur'Aini Purnamaningsih]]>;
<![CDATA[Tri Sunarsih]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2910
<![CDATA[The objective of this study were describe the stock and demand for blood during the Covid-19 pandemic at the Blood Donation Unit PMI Sleman Regency in 2019-2020 as well as efforts to meet the availability of blood stocks. This research was a quantitative descriptive study with a retrospective approach. The results showed that due to the Covid-19 pandemic, the amount of blood stock and demand at Blood Donation Unit PMI Sleman Regency increased. The number of blood stocks in 2019 before the Covid-19 pandemic was 11.500 blood bags with a demand for blood coming in as many as 11.487 bags. Meanwhile, the number of blood stocks in 2020 during the Covid-19 pandemic was 12.303 blood bags with a demand for blood coming in as many as 12.515 bags. So that during the Covid-19 pandemic taking place in 2020 as many as 212 requests for blood (1,69%) could not be fulfilled due to a lack of blood supply. Lack of blood stock caused by the reduced presence of donors due to the Covid-19 pandemic. Efforts to fulfill blood stock are carried out by improving services and supporting facilities.]]>
<![CDATA[Erectile Dysfunction and COVID-19: a Case Report ]]>
<![CDATA[Gembong Satria Mahardhika]]>;
<![CDATA[Nastiti Maharani]]>;
<![CDATA[Theodore Dharma Tedjamartono]]>;
<![CDATA[Efriadi Ismail]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2715
<![CDATA[Coronavirus Diesease-2019 (COVID-19) infection is suspected to affect the sexual behavior and function. The vascular damage related to COVID-19 can affect the impairment of bed blood vessel of penile and finally make the erectile dysfunction (ED). This problem is one of the most common sexual problem in man, with the prevalantion between 13 until 28% at the 40-80 years old, and the incidence increases with higher age. At this time, no data about the effect of COVID-19 to sexual behavior. There was one case of COVID-19 with erectile dysfunction who was treated at Kemayoran Athletes Village COVID-19 hospital. Erectile dysfunction is influenced by several factors; including psychogenic, neurogenic, and infectious. The diagnosis of erectile dysfunction is determined based on the results of history taking and physical examination, using the standard questionnaire (IIEF-5/International index of erectile function-5). A further review is needed to exclude a particular cause, the management can be determined based on the etiology.]]>
<![CDATA[The Effectiveness of Antidepressant Combined with Quranic CBT in Reducing Anxiety Level of Moslem Outpatient withh Anxiety Disorder in Sultan Agung Islamic Hospital in Semarang ]]>
<![CDATA[Metrikana Novembrina]]>;
<![CDATA[Dinia Eko Kusmianti Putri]]>;
<![CDATA[Ferika Indrasari]]>;
<![CDATA[Wahyu Setyaningsih]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2947
<![CDATA[Anxiety disorders is an emotional condition in which a person feels excessively anxious and it is generally caused by the excessive perception of a particular danger threatens the security of an individual and sometimes interferes with the daily activities and social interaction of an individual. This study aimed to determine the effectiveness of the Quranic CBT in reducing the anxiety level of the outpatient with anxiety disorder in Sultan Agung Islamic Hospital, Semarang. This was a treatment trial research using purposive sampling technique. In this study as much as 20 patients diagnosed with anxiety disorders and in the treatment with antidepressants were randomly divided into 2 groups. Group 1 was the patients undergoing therapy with antidepresant and also given Quranic CBT. Group 2 was the patients using antidepressant drugs and not given Quranic CBT therapy. This showed that the Quranic CBT method was effective in reducing the anxiety level.]]>
<![CDATA[The Correlation Between Adiponectin Levels With C-Reactive Protein in Adult Obese Non-Diabetic Among Staffs of DR. M. Djamil Hospital Padang ]]>
<![CDATA[Dian Eka Putri]]>;
<![CDATA[Rismawati Yaswir]]>;
<![CDATA[Desywar Desywar]]>;
<![CDATA[Efrida Efrida]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2719
<![CDATA[The adiponectin and C-reactive protein (CRP) are markers of chronic low-grade inflammation related to obesity. This study aims to determine a correlation between adiponectin level and CRP level in adult obese individuals. This study was analyzed with a cross-sectional design of 55 subjects at Dr. M Jamil Central Hospital Padang from January to September 2019. The subjects included were type 1 obese (25≤BMI≤29.9 kg/m2) and type 2 obese (BMI 30.0 kg/m2). Enzyme-linked immunoassay (ELISA) was used to measure adiponectin and High Sensitivity C-Reactive Protein (Hs-CRP) levels. Univariate statistical analysis is processed and presented in distribution, frequency, mean (standard deviation), median (minimum-maximum value). Bivariate data were analyzed using the Pearson correlation test, significant if p<0.05. The study consists of 16 males and 39 females. The mean age was 35 years old (the range 23 to 57 years old), the mean BMI was 30.8 (4.5) kg/m2. This study consists of 28 subjects, type 1 obese and 27 types II obese. The mean adiponectin level in type 2 obese is lower than in type 2 obese groups. The mean CRP levels are high in all populations. Pearson ln-adiponectin and CRP correlation test in the entire population: r =-0.105 (p=0.444). ]]>
<![CDATA[Tocilizumab In Severe To Critical Confirmed COVID-19: A Case Series At Ulin Referral Hospital Of South Kalimantan ]]>
<![CDATA[Haryati Haryati]]>;
<![CDATA[Fidya Rahmadhany Arganita]]>;
<![CDATA[Widya Ramadhaniati]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2862
<![CDATA[Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes pneumonia. The clinical severity of COVID-19 is related to the presence of a “cytokine storm” that causes overproduction of inflammatory mediators such as interleukin (IL)-6. Tocilizumab (TCZ) as an IL-6 inhibitor is subject of major studies as a potential therapeutic agent. This study reported 20 cases of COVID-19 patients being treated with the IL-6 inhibitor TCZ beside standard therapy. Patients were followed up on clinical, laboratory and chest x-rays before and after the administration of therapy which were report descriptively. The oxygen saturation of patients who survived shows rapid improvements. The laboratory results showed that CRP decreased after administration TCZ immediately. Meanwhile, other markers improve slowly, such as leucocytes, Neutrophyl Lymphocyte Ratio (NLR), Absolute Lymphocyte Count (ALC) and Lactate Dehydrogenase (LDH) but ferritin was tended to fluctuate. In chest X-ray’s, infiltrate bilateral on admission began to diminished until almost disappeared on the 14th day after TCZ. From 20 patients, 80% of patients survived with improvement in clinical, laboratory and chest X-rays, while the rest death with a good response on first therapy but fluctuated and worsened before death. Tocilizumab can be considered to provide clinical improvements in severe and critical COVID-19 patients.]]>
<![CDATA[A Survival Analysis with Cox Regression Interaction Model of Type II Diabetes Mellitus in Indonesian ]]>
<![CDATA[Simeftiany Indrilemta Lomo]]>;
<![CDATA[Sugiyarto Sugiyarto]]>;
<![CDATA[Endang Darmawan]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2942
<![CDATA[Type II diabetes mellitus is a metabolic syndrome characterized by hyperglycemia. Diabetes is still one of the world's health threats where the number of people with disabilities and mortality rates continue to increase over time. This study aims to analyze the survival of patients with type II diabetes mellitus as well as factors that affect it using survival analysis. This study used medical record data of type II diabetes mellitus patients undergoing treatment for the period 2015-2019 at PKU Muhammadiyah Gamping Hospital and PKU Muhammadiyah Hospital Yogyakarta.]]>
<![CDATA[Analysis of Compliance Level of Nurse Personal Protection Use in Royal Prima General Hospital ]]>
<![CDATA[Sri Lestari Ramadhani Nasution]]>;
<![CDATA[Nadratul Ulya]]>;
<![CDATA[Sinta Ayu Setiawan]]>;
<![CDATA[Sri Wahyuni Nasution]]>
<![CDATA[ Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT ]]>
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DOI: 10.33533/jpm.v15i1.2909
<![CDATA[This study aimed to determine the level of compliance with the use of personal protective equipment as prevention of work accidents. This research was conducted using quantitative methods with a cross-sectional approach in the Emergency Unit and Intensive Care Unit at the Royal Prima General Hospital. The results showed a relationship between age and adherence to the use of PPE with p = 0.002. There is no correlation between years of service and compliance with the use of PPE with p-value = 0.75. There is a relationship between knowledge of compliance with the use of PPE with p-value = 0.009. There is a relationship between attitudes towards compliance with the use of PPE with p = 0.002. There is a relationship between the availability of facilities and compliance with the use of PPE with a p-value of 0.000. There is a relationship between compliance training on the use of PPE with p-value = 0.004. There is a control relationship to compliance with the use of PPE with p-value = 0.002.]]>
