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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
ISSN : 02163438     EISSN : 26211122     DOI : -
Core Subject : Health,
Arjuna Subject : -
Articles 244 Documents
Nevus Comedonicus, a Rare Case : Dermoscopic and Histopathological Findings Nugrohoaji Dharmawan; Endra Yustin Ellistasari; Oyong Oyong; Adniana Nareswari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v15i1.2168

Abstract

Nevus comedonicus is an extremely rare adnexal hamartoma of pilosebaceous apparatus, with approximately 200 cases reported in the literature so far. It appears as cluster of adjacent honeycomb-like dillated follicular openings with firm pigmented keratin plugs resembling comedones.The comedones oftentimes arranged in linear pattern paralled to Blaschko’s lines. We report a case of a 5-year-old boy with open brown to black comedones in a linear pattern localized on the back of the left thigh that appearing since birth. Pain, itch and discharge were not obtain. There were some episodes of infection, due to manual removal done by his mother which left some hypertrophic scars. Dermoscopic examination revealed the distinctive pattern consisting of pigmented, sharply demarcated keratin plugs of 1-3 mm in diameter, some open pores, multiple structurless, various shades of brown homogenous circular areas surrounding the plugs. Histopathological examination showed an aggregation of dilated follicular infundibulum with laminated keratinous material plugging. This case report prove that dermoscopy examination, a simple non-invasive diagnostic tool is very helpful in diagnosing nevus comedonicus. We recommend this tool to differentiate the diagnosis of other rare epidermal nevi while histopathological examination should be performed only in uncertain cases.
Spatial-Temporal Analysis of Dengue Hemorrhagic Fever (DHF) in Kendari City 2014-2018 Sri Aprilianti Idris; Muhammad Sultanul Aulya
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2227

Abstract

This study aims to determine the spatiotemporal pattern of cases of dengue hemorrhagic fever (DHF) in Kendari City during 2014 - 2018 and to see the correlation of cases of dengue hemorrhagic fever (DHF) with rainfall, larva free index (LFI) and population density in Kendari city. This study uses an ecological study design that is analytic or an analytic observational study. Sampling in this study was carried out by total sampling, so the sample in this study were residents who suffered from dengue hemorrhagic fever (DHF) microcopically which was integrated in the monthly reports of cases of dengue hemorrhagic fever (DHF) at the Kendari City Health Office during 2014-2018, namely totaled 1,406 people. This research was conducted in August-October 2020. The data were analyzed temporally (graphically) and statistically using the Spearman-rho correlation test. The data were processed using GeoDa 1.6.7, QuantumGIS 10.3 and IBM SPSS version 20 programs. The study showed that the spatial pattern of cases of dengue hemorrhagic fever (DHF) in Kendari city showed a random pattern (Moran's index = 0.47745). The temporal trend of DHF cases increases at the beginning of the year entering the rainy season (January - July) and decreases at the end of the year after the rainy season (August - December). Based on the statistical test, there was a significant correlation between rainfall (p = 0.000 <0.05) and the incidence of dengue fever and there was no significant correlation between larvae free rate (p = 0.502> 0.05); population density. (p = 0.440> 0.05) with the incidence of DHF.
Profile Evaluation of Medication, Cost Comparison, and Clinical Outcome of Human and Analog Insulin Treatment to Type-2 Diabetes Mellitus Outpatient at Medistra Hospital Year 2012-2013 Elisabeth Ninung Yuliarti; Yusi Anggriani; Dian Ratih Laksmitawati; Prasasta Sutedjo
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2007

Abstract

The data collection was conducted retrospectively, taking samples of 121 outpatients, of which 83 outpatients were evaluated for their clinical outcome. The medication profile data were collected from the medicine administration at the Hospital Pharmacy Installation. The clinical outcome data, such as fasting plasma glucose (FPG), two-hour postprandial plasma glucose (2HPP), and Hemoglobin A1c (HbA1c), were garnered from the patients’ medical records. The cost data were collected from the outpatients’ payment receipts provided by the Hospital’s Financial Department. Kolmogorov Smirnov normality test was applied in this research. The research result suggests that after Mann Whitney Test, the human and analogue insulin were not significantly different seen from the clinical outcome result showing FPG (p=0.676), 2HPP (p=0.175), HbA1c (p=0.0445) and from the cost result (p=0.795). Furthermore, the research also shows that the average cost of 30-day medication of single human insulin was Rp3,190,997.43, while the one of analogue insulin was Rp3,188,832.35. In conclusion, the research finds out that if seen from the cost (p=0.795), the human and the analogue insulin were not significantly different.   
CT Pulmonary Angiogram with Reduced Radiation Exposure at Low Tube Kilovoltage Ahmed Abdullahi Hashi
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2197

Abstract

This study's primary goal is to assess the image quality and radiation dose of the low-dose 80kV computed tomography pulmonary angiogram (CTPA) protocol compared to the standard 100kV CTPA protocol for the assessment of pulmonary embolism (PE). The study consisted of 100 patients who had clinically suspected pulmonary embolism and required a CTPA. Patients underwent imaging with a 320-row multi-detector Toshiba Aquilion One Genesis Edition in the absence of the proprietary radiation reduction software known as forward projected model-based Iterative Reconstruction Solution (commercial acronym 'FIRST'). Participants were divided into two groups: A and B.  Group A was composed of 50 patients who were allocated to standard CT protocol using a 100 kV exposure setting and all other settings set as a standard by the manufacturer.  Group B was composed of 50 patients who were allocated to a CTPA with a low-dose 80kV protocol, standard deviation level 8, an effective mAs of 258, reconstruction algorithm-kernel FC 51 within the lung window, and tube current modulation. A considerable decrease in radiation dose was observed with the low-dose CTPA protocol. The mean radiation dose was also decreased by 66% while using the 80kV protocol than when utilising a standard 100kV technique; this was achieved without compromising this study's diagnostic value. Furthermore, the contrast enhancement was considerably more significant, up to 40% higher when using 80kV. The study found that a low tube voltage of 80kV CTPA protocol resulted in a considerable decrease in radiation dose and improved contrast enhancement without sacrificing the examinations' diagnostic utility.
Decreas of BCL-2 Expression by Ethanol Extract of Ocinum basilicum L. Leaves in Breast Cancer Cells Devi Nisa Hidayati; Fatimatuz Zahroh; Lina Wahyuni; Ibrahim Arifin
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v15i1.2491

Abstract

Ocimum basilicum L has proven to have in vitro cytotoxic activity against breast cancer cells. Pathways that cause cell death can involve one of the proteins, which is BCL-2. This study aims to determine the decrease of BCL-2 protein expressions in breast cancer cells (T47D and MCF-7) tat are treated with the ethanol extract of Ocimum basilicum L. Ocimum basilicum L. was extracted using the maceration method with 70% ethanol solvent. The concentration of ethanol extract of Ocimum basilicum L. used to see the expression of BCL-2 protein in T47D and MCF-7 cells was 199 µg/ml and 388 µg / mL. The observation of BCL-2 protein expression is using immunocytochemical methods of T47D and MCF-7 cancer cells. The results showed that the ethanol extract of Ocimum basilicum L could reduce BCL-2 protein expression in breast cancer cells (T47D and MCF-7) at concentrations of 199 µg/ml and 388 µg/ml, respectively.
Effects of Sedentary Behavior and Fast-Food Consumption Habit on Body Mass Index Among Obese Children In Siwalankerto Village, Surabaya Desta Ayu Cahya Rosyida; Setiawandari Setiawandari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2238

Abstract

Obesity is the basis of various non-communicable diseases such as diabetes, hypertension, and cardiovascular diseases, which are currently major health problems in Indonesia. Furthermore, other consequences that may arise are a greater risk of social and psychological problems such as stigmatization and low self-confidence. Hence, researchers expect to change the pattern of sedentary behavior and the fast-food consumption habit among obese children. This research was a quantitative study. The treatments were applied towards two groups, and the conditions before and after treatment were compared. The results revealed that the mean Body Mass Index (BMI) among children in the sedentary behavior group before and after the intervention were 28.2 (Obesity I) and 19.2 (Normal BMI), respectively. Meanwhile, the mean BMI in the fast-food consumption habit group before and after the intervention were 28.2 (Obesity I) and 20.5 (normal BMI), respectively. The statistical analysis showed a significant difference in the decrease in BMI  between the two groups (p<0.05). The sedentary behavior group showed a higher mean value than the fast-food habit group, namely 20.0 and 19.6, respectively. Thus, it can be concluded that the intervention in the sedentary behavior group was more influential than the fast-food habit group.
Impact of Covid-19 on the Outcomes of Basic Immunization in Health Facilities Retno Setyo Iswati; Indria Nuraini
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2170

Abstract

The purpose of this study was to determine the impact of Covid 19 on basic immunization coverage, oriented to the number of Covid 19 cases mapped in the red, yellow, and green. This research provides the advantage of making a policy to improve children's health during a pandemic, particularly in preventing diseases that can be anticipated by immunization, such as tuberculosis, diphtheria, hepatitis, tetanus, meningitis, polio, and measles. This research can also be used as a basic for immunization in health facilities while still implementing health protocols. This study's results can be implemented in primary health facilities such as the Puskesmas, Posyandu, Poskesdes, or Midwife Independent Practice. This study's results indicate that immunization coverage <95% is mostly found in the red zone area of Pentabio 1 and 2 immunization, as well as measles. Chi-square test found that there was no significant relationship with basic immunization coverage.
Gender Differences in Sociademographic Characteristics and Risk Factors Among Condyloma Acuminata Patients in DR. Moewardi General Hospital Surakarta Adniana Nareswari; Prasetyadi Mawardi; Arie Kusumawardhani; Endra Yustin Ellistasari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2169

Abstract

Condyloma acuminata (CA) known as anogenital wart is the most frequent sexually transmitted infection worldwide. This highly infectious disease is caused by the human papilloma virus, whose its high reccurence rates contribute to direct medical costs, productivity loss and increased psychosocial impact. Thus, the prevention of this viral disease is more important than focusing on its treatment. This cross sectional retrospective study assesed the gender differences in sociodemographic characteristics and sexual risk factors of CA patients. There were 94 newly diagnosed CA patients, 47 males (50%) and 47 females (50%) during the period of January 2013- December 2017. The demographic data were taken from medical record and the additional data about the risk factors were from the questionnaires. Chi-square test was performed to compare between genders and p < 0.05 was considered statistically significant. There was significant difference between genders on all sociodemographic characteristics (age, occupation, education, marrital status) and risk factors (HIV/AIDS infection, condom using, age at the first sexual intercourse, number of lifetime sexual partner, type of intercourse) among CA patients. Our study revealed that male CA patients were mostly single, employed and multipartner, while CA female patients were mostly married, housewives and singlepartners.
Analysis of Cadre Compliance Levels in Running Health Protocol in the Era of Pandemic Covid-19 in Puskesmas Limo Depok Sri Wahyuningsih; Hany Yusmaini; Erna Harfiani; Meiskha Bahar
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2217

Abstract

Covid-19 outbreak that originated in Wuhan's city is spreading very quickly and is currently a pandemic worldwide. Transmission through droplets that come out of the patient's nose or mouth, whether symptomatic or asymptomatic.  Efforts to prevent and fight COVID-19 must be carried out jointly with the community's cooperation and require strong discipline by washing hands frequently, maintaining distance, wearing masks, staying at home, and increasing body power. The purpose of this study was to determine the level of cadre compliance  in carrying out health protocols in the era of the Covid-19 pandemic. This research method with a cross-sectional approach. The respondents were cadres of Limo Health Center, Depok. It was total sampling. The research instrument used a questionnaire of Google Form and analyzed using Chi-Square. The results showed that most of the respondents were included in the 46-60 year interval (51.4%) were highly educated, tertiary education (70%), knowledgeable (54.3%), unemployed (87.1), obeyed the protocol. Health (50%). Compliance increases in the elderly, higher education, sufficient knowledge, work status. conclusion there is no relationship between age (p = 0.632), education level (p = 0.794), knowledge level (p = 0.253), work status (p = 0.074) and compliance with the Covid-19 health protocol.
Effect of Hemoglobin Levels Pregnant Women on the Predictive Value for Preeclampsia of ROT (Roll-Over Test) Nina Hidayatunnikmah; Tetty Rihardini
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2261

Abstract

Preeclampsia is a medical condition which accounts for the global incidence of maternal mortality of 76,000/year and infant mortality of 500,000/year. Early preventive action is a critical dimension to reduce the risk to the mother and the fetus. Roll Over Test (ROT) is one of the predictors of preeclampsia conducted in the 2nd trimester. High hemoglobin levels in pregnant women can lead to pregnancy hypertension, which can potentially lead to preeclampsia. This study aims to analyze the effect of hemoglobin levels on the predictive value for preeclampsia of ROT (Roll Over Test) among pregnant women. The benefits of this study are to get preventive method updates to decrease the incidence of preeclampsia in pregnant women as early as possible and to review the policy of giving Fe to all pregnant women from the 1st trimester to the 3rd trimester. The study was conducted for three months in the work area of Siwalankerto Community Health Center, Surabaya. Data on hemoglobin levels were obtained from the MCH booklet for pregnant women. ROT's preeclampsia's predictive value was obtained by checking supine values and left lateral blood pressure among 30 pregnant women. A statistical test was performed using a logistic regression test. Based on 30 samples of pregnant women, the results showed that 16 pregnant women had hemoglobin levels of >13gr/dl (53.3%), and 14 pregnant women (46.7%) had a positive predictive value of ROT. The effect test analysis results showed a positive relationship between hemoglobin levels and the predictive value for preeclampsia (p=0.04, B=1.299). Thus, pregnant women who experienced an increase in the hemoglobin levels of 1 g/dl had a potential of 1.299 times to have a positive ROT value.

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