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Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Pembangunan Nasional Veteran Jakarta
ISSN : 02163438     EISSN : 26211122     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 244 Documents
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The Relationship Of Online Game Addiction To Changes In Emotional Regulation Of Medical Faculty Students At Maranatha Christian University Ivone, July; Sinaga, Irvan Amanda; Hasianna, Stella Tinia
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.10739

Abstract

Online games are a type of game that can be played on various devices and connected to the Internet network so that it can be used to play online games, if played continuously with a long intensity can cause a person to be addicted to online games and have an impact on mind disorders and emotional and mental health. Faculty of Medicine students have a busy schedule, so they play online games to overcome the boredom. This study is to determine the relationship between online game addiction and changes in emotional regulation of Maranatha Christian University Medical students. This study used an analytical method with a cross sectional research design with a total research sample of 132 students. The results of the spearman correlation test where the p value = 0.001 is obtained, meaning that there is a very significant correlation between online game addiction and emotional regulation. The r value is 0.688, which means that there is a strong relationship between online game addiction and emotional regulation and has a positive pattern. There is a strong relationship between online game addiction and emotional regulation in Maranatha Christian University Medical faculty students class of 2021 and 2022.
Calcitonin Gene-related Peptide (CGRP) Inhibitors in Episodic and Chronic Migraines: A Multiple Treatment Comparison (MTC) Meta-Analysis Shita Meliani, Dewa Ayu Sri; Haq, Abiyyu Didar
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.12182

Abstract

Migraine is a common neurological disorder affecting approximately 15% of adults worldwide, characterized by recurrent pulsating headaches. Conventional treatments often provide insufficient relief and may cause medication-overuse headaches. Calcitonin Gene-Related Peptide (CGRP) inhibitors have emerged as a novel preventive therapy by targeting the underlying migraine pathophysiology. This meta-analysis aimed to evaluate the efficacy and safety of CGRP inhibitors in reducing monthly migraine days (MMD) among patients with episodic and chronic migraine. A systematic search was conducted in ScienceDirect, PubMed, CENTRAL, and Wiley up to January 29, 2023, including randomized controlled trials with MMD as the primary outcome. Forty-two studies were analyzed qualitatively, and 32 studies were included in quantitative synthesis using random-effects models. Among 22,295 patients from studies published between 2013 and 2022, CGRP inhibitors significantly reduced MMD compared to placebo (Mean Difference -2.12; 95% CI -2.41 to -1.84; p=0.02), with galcanezumab showing the largest effect. Safety profiles were comparable to placebo, supporting their role in migraine prevention and guideline recommendations.
Efficacy and Safety of Pravastatin in Placental-Related Disorders: Systematic Review And Meta-Analysis Of Randomized Controlled Trials: english Saputra, Gede Ardi; Pandiangan, Asri; Suryatman, Muhammad Villiandy; Swastini, Ni Putu
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Placental-related disorders impact over 33% of pregnancies. Several of these syndromes lead to higher rates of maternal and fetal death and morbidity and can have long-term health consequences. Several RCTs have found that pravastatin is associated with a significant reduction in the incidence of preterm preeclampsia and preterm birth. However, alternatives require substantial evidence. On the methods, two writers assessed the risk of bias. The Cochran test was used to assess heterogeneity among studies. The Mantel-Haenszel technique was used to obtain the results. The study's results were described using forest plots. The study used six randomized controlled trials. Findings showed a reduced risk of preeclampsia, preterm birth, and NICU admission in pregnant women taking pravastatin. There was no significant reduction in the risk of neonatal respiratory distress, congenital disorders, and adverse events of headache, heartburn, and musculoskeletal pain. Our conclusion, this study suggests that pravastatin use may have beneficial effects in reducing the risk of placental-related disorders in patients.
The Relationship Between Tumor Size Parameters and Carcinoembryonic Antigen (CEA) Levels in Colorectal Adenocarcinoma Based on Contrast-Enhanced Abdominal CT Scan Prasatya, Dewa Putu Jaya; Margiani, Ni Nyoman; Wijaya, I Gusti Agung Gede Mahendra; Putra, I Wayan Gede Artawan Eka
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.12265

Abstract

Introduction: Colorectal adenocarcinoma is a common malignancy with high mortality. Carcinoembryonic Antigen (CEA) is widely used as a tumor marker, while contrast-enhanced CT scans provide tumor size parameters. The correlation between these parameters and CEA remains unclear. Objective: To analyze the relationship between tumor area and thickness on contrast-enhanced CT scan and CEA levels in colorectal adenocarcinoma. Methods: A retrospective cross-sectional study was conducted at RSUP Prof. Dr. I.G.N.G. Ngoerah (2018–2023) involving patients with available CT scan and CEA data. Pearson correlation and multivariate regression were applied. Results: Tumor area showed a significant positive correlation with CEA (r = 0.513; p = 0.001), independent of age and sex. Tumor thickness was not significantly correlated (r = 0.196; p = 0.224). Conclusion: Tumor area correlates significantly with CEA levels, whereas tumor thickness does not. Tumor area may serve as an additional indicator in colorectal cancer evaluation.

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