Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

3.264

P-Index

This Author published in this journals

All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medical Journal of Indonesia Berkala Ilmu Kesehatan Kulit dan Kelamin Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan JOURNAL LA MEDIHEALTICO eJournal Kedokteran Indonesia Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Kedokteran Meditek Indonesian Journal of Biomedicine and Clinical Sciences

Shannaz Nadia Yusharyahya

Departemen Dermatologi Dan Venereologi, Fakultas Kedokteran Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo Jakarta, Indonesia

Author-ID : 1162448

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 26 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3

Potential role of fenugreek (Trigonella foenumgraecum) in the prevention of skin aging Shannaz Nadia Yusharyahya
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 53, No 1 (2021)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Skin aging is a process influenced by several factors, including estrogen.Estrogen modulates the physiology of the skin, and its deficiency inpostmenopausal women accelerates skin aging. Administration of estrogencan delay the skin aging process. Phytoestrogens are estrogen-like compoundsderived from plants that administered via oral as well astopical routes.Trigonella foenum-graecum, commonly known as fenugreek, is one plantscontaining phytoestrogens. Several studies have been conducted on thephytoestregonic activity of fenugreek. Fenugreek extract exhibits estrogenicactivity, as observed in the study of mouse and rat reproductive organs.Fenugreek exhibits estrogenic activity in the reproductive organs of a rat, aswell as demonstrates positive effects on the skin by topical administration.This review explored the fenugreek as the source of phytoestrogens and itsrole in delaying skin aging.

Ultraviolet phototherapy for treatment of various dermatoses Irwan Saputra Batubara; Larisa Paramitha Wibawa; Erdina Pusponegoro; Windy Keumala Budianti; Githa Rahmayunita; Shannaz Nadia Yusharyahya
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 53, No 4 (2021)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005304202107

Ultraviolet (UV) radiation has been applied to treat many chronic skin diseases. Based on the wavelength, UV radiation consists of three types, namely ultraviolet C (UVC), ultraviolet B (UVB), and ultraviolet A (UVA). The types of UV that are widely used in dermatology are narrowband ultraviolet B (NB-UVB), broadband ultraviolet B (BB-UVB), UVA1, and psoralen combined with UVA (PUVA). The interaction between UV and the skin determines the effectiveness of phototherapy. The biological effects of UV are used in the management of inflammatory skin diseases, malignancies, and various rare dermatoses. Apart from these benefits, UV increases the risk of photoaging and skin cancer. Therefore, further researches are necessary to enhance the effectiveness and safety of phototherapy. This literature review discusses the role of phototherapy in various dermatoses other than psoriasis and vitiligo.

Angka Kejadian Hiperpigmentasi Pasca Inflamasi pada Pasien Akne Vulgaris Sedang Tipe Kulit IV-V yang Diterapi Gel Benzoil Peroksida 2,5% Uji Klinis, Acak, Buta Ganda Irma Bernadette S. Sitohang; Putu Siska Virgayanti; Shannaz Nadia Yusharyahya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 3 (2019): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Latar belakang: Akne vulgaris (AV) merupakan peradangan kronis folikel pilosebasea dengan manifestasi klinis berupa komedo, papul, pustul, nodus dan pseudo kista yang bersifat swasirna. AV digolongkan atas tiga kategori, yaitu akne vulgaris ringan (AVR), sedang (AVS) dan berat (AVB). Rekomendasi Global Alliance dalam penanganan AVS meliputi antibiotik, asam retinoat, dengan atau tanpa benzoil peroksida (BPO). Kombinasi antibiotik dan BPO direkomendasikan untuk mengatasi masalah tersebut meskipun pada tipe kulit IV-V, hiperpigmentasi pasca inflamasi merupakan masalah yang sering dikeluhkan pada penggunaan BPO. Tujuan: Membandingkan efektivitas, efek samping dan kejadian hiperpigmentasi pasca inflamasi (HPI) pada penggunaan BPO sebagai paduan terapi lini pertama AVS pada tipe kulit IV-V Fitzpatrick. Metode: Penelitian analitik dengan desain uji klinis acak tersamar ganda membandingkan dua sisi wajah yang diberikan paduan terapi lini pertama. Sisi wajah perlakuan diberikan gel BPO 2,5% sedangkan kelompok kontrol gel plasebo. Hasil: Pada minggu ke-2,4,6,8 didapatkan penurunan persentase total lesi sebesar 51,47%, 71%, 75%, 82,84% pada kelompok BPO dan 30%, 53,75%, 62,28, 71% pada kelompok plasebo (p<0,001) Efek samping dan kejadian HPI pada minggu ke 2,4,6 dan 8 tidak berbeda bermakna. Simpulan: Penggunaan BPO sebagai bagian dari paduan terapi lini pertama AVS lebih efektif, tidak meningkatkan efek samping ataupun kejadian HPI.

Tata Laksana Komprehensif Dermatitis Stasis pada Geriatri Shannaz Nadia Yusharyahya; Natalia Rania Sutanto; Adhika Ayu Lestari; Rhida Sarly Amalia; Melody Febriana Andardewi
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Dermatitis stasis merupakan penyakit kulit inflamasi yang umum terjadi di ekstremitas bawah, ditandai dengan eritema, skuama, erosi, krusta, dan terkadang juga dapat ditemukan vesikel, serta ulserasi kecil di kulit yang dikenal sebagai ulkus stasis atau ulkus venosum. Faktor risiko dermatitis statis antara lain usia di atas 50 tahun, obesitas, dan jenis kelamin perempuan. Dilaporkan tiga kasus dermatitis stasis pada pasien geriatri laki-laki yang datang ke Rumah Sakit dr.Cipto Mangunkusumo dan ketiganya disertai komorbiditas obesitas. Tata laksana pada ketiga pasien ini melibatan departemen lain (multidisiplin) dan membuahkan hasil yang baik.

Mekanisme Penuaan Kulit sebagai Dasar Pencegahan dan Pengobatan Kulit Menua: Mechanism of Skin Aging Shannaz Nadia Yusharyahya
eJournal Kedokteran Indonesia Vol 9, No. 2 - Agustus 2021
Publisher : Faculty of Medicine Universitas Indonesia

Seiring dengan meningkatnya populasi geriatri di Indonesia, masalah penuaan kulit juga turut meningkat. Pada populasi tersebut terjadi berbagai perubahan kulit sehingga kelainan yang ditimbulkan juga berbeda. Stres oksidatif merupakan mekanisme yang diduga kuat sebagai penyebab utama penuaan kulit. Penuaan kulit merupakan proses kompleks yang melibatkan faktor intrinsik dan ekstrinsik. Faktor intrinsik yang berperan adalah genetik, metabolisme sel, dan perubahan hormonal. Selain itu, terdapat faktor ekstrinsik seperti radiasi ultraviolet, inframerah, dan karsinogen lingkungan yang turut berperan pada penuaan kulit. Kedua faktor tersebut menyebabkan perubahan di seluruh lapisan kulit. Untuk mengatasi penuaan kulit, kini telah tersedia berbagai modalitas terapi, namun untuk menentukan terapi yang paling sesuai perlu diketahui fisiologi kulit menua, mekanisme penuaan kulit, dan manifestasi kelainan klinis kulit menua. Secara fisiologi terjadi perubahan permeabilitas, biokimia, vaskularisasi, termoregulasi, respons terhadap iritan, respons imunitas, kapasitas regenerasi, respons terhadap cedera, persepsi neurosensori dan pada tingkat genom. Jumlah sel epidermal dan laju pergantian epidermal menurun sedangkan di adneksa terjadi penurunan jumlah kelenjar sebasea yang mengakibatkan kulit kering dan mudah pecah. Penurunan jumlah melanosit menyebabkan warna rambut menjadi abu-abu keputihan dan muncul pigmentasi atipik di kulit. Folikel rambut kurang aktif sehingga meningkatkan kerontokan dan kebotakan. Di lapisan basal ukuran sel berkurang dan rerata ukuran sel bertambah. Sel keratinosit menjadi lebih pendek dan besar di kulit yang menua. Kata kunci: geriatri, mekanisme penuaan kulit, patofisiologi. Skin Aging Mechanism as A Basic Prevention and Treatment of Skin Aging Abstract Growing geriatric population generates a rise of aging issues. Process of aging develops multiple skin changes that further emerge other related skin problems. Oxidative stress is believed playing vital role related to aging. The aging process in the skin is complex and influenced by intrinsic and extrinsic factors. Intrinsic factors can be in the form of genetics, cell metabolism, and hormonal changes. Meanwhile, for extrinsic factors, such as exposure to ultraviolet, infrared, and carcinogenic agent also have crucial part in aging process. These factors contribute to all layers of the skin. Nowadays, many treatment modalities available to reverse skin aging, however, better understanding on skin aging mechanism, the pathophysiology, and clinical manifestations of aging skin is important to choose the appropriate treatment for patients. In aging, there are physiological changes in permeability, biochemical structures, vascularisation, thermoregulation, irritative response, immunity response, regenerative capability, inflammatory response, neurosensory perception and in genom level. The number of epidermal cells and epidermal overturn rate decline while there is also reduction of sebaseous glands at adnexa which both are accounted for skin xerosis. Decreasing melanocytes can caused gray hair and atypical pigmentation. Hair follicles also show less activity resulting in hair loss. Basal layer cells are downsizing and rise of average cells size are occured. Keratinocyte becomes shorter and bigger in aging skin. Keywords: geriatric, mechanism, skin aging, pathophysiology.

Development of a Questionnaire Evaluating the Knowledge, Attitude, and Practice on Geriatric Dermatology among Elderly Caregivers Shannaz Nadia Yusharyahya; Valdi Ven Japranata; Christine Lieana; Lili Legiawati; Rinadewi Astriningrum; Wresti Indriatmi
eJournal Kedokteran Indonesia Vol 10, No. 3 - Desember 2022
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23886/ejki.10.228.228-37

Information concerning the extent of knowledge, attitude, and practice of elderly caregivers about dermatological care are still limited. This present study aimed to develop a tool with decent validity and reliability to delineate such profiles. A questionnaire was designed by geriatric dermatology experts, followed by content validation and reliability tests using Aiken’s V coefficient, Kuder-Richardson Formula 20 (KR-20) or Cronbach’s α, and Pearson’s correlation. The developed instrument was tested on elderly caregivers, before and after education. Obtained data were analyzed using appropriate inferential statistics. We found that the Aiken’s V coefficient for each item was ≥0.70; KR-20 in knowledge section was 0.81; Cronbach’s α in attitude and practice section were 0.81 and 0.80, respectively; and Pearson’s correlation in all sections was above 0.80. Significant disparities were observed in the initial knowledge (p=0.005) and attitude (p=0.020) based on academic levels. In addition, overall scores generally increased upon education (p<0.001). Therefore, the questionnaire is valid and reliable for assessing elderly caregivers' competencies in geriatric dermatology of which could be improved by education.

Atypical mycobacterial infection mimicking carbuncle in an elderly patient: A case report Barros, Terlinda; Legiawati, Lili; Yusharyahya, Shannaz Nadia; Sularsito, Sri Adi; Wihadi, Imelda
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 1, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: Atypical mycobacterium infection occurs under certain skin conditions, namely the disruption of skin integrity and mucous membranes accompanied by the reduction of cellular immunity. However, atypical mycobacterial infection in elderly patients is rarely reported. Case: A 64 years old male patient, complained of red lumps on the upper-backfor a month, accompanied by mild fever and minimal pain. Three months before, the patient had accupuncture on the neck and upper back. Physical examination showed multiple miliar to lenticular sized papules and pustules on an erythematous-violaceus base with hard and immobile palpable nodes and infiltrate. After clinical and laboratory workup, the patient was diagnosed withcarbuncle with Candida spp colonization. The treatment consisted of systemicantibiotics and topical antifungals. There was no clinical improvement after 3 weeks. Histopathology and laboratory results suggested atypical mycobacterium infection. Discussion: Atypical mycobacterium infection should be considered in elderly patients with skin and soft tissue infections that show no clinical improvement tostandard therapy.

Atopic dermatitis in the elderly Irawan, Yudo; Rihatmadja, Rahadi; Legiawati, Lili; Yusharyahya, Shannaz Nadia; Sularsito, Sri Adi
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Atopic dermatitis (AD) is a recurrent skin inflammation accompanied by itching. The incidence of AD is increasing worldwide. AD, which persists until elderly or with an onset during elderly, is known as senile AD. It has different prevalence and clinical features from other AD stages. Senile atopic dermatitis affects males more than females, which is different from other stages of AD. Skin manifestation of senile AD is similar with the adult stage of Hanifin-Rajka criteria, but can be atypical. The typical feature of senile AD is eczematous dermatitis around a free-lesion fossa. Other common clinical manifestations are erythroderma and non- specific chronic dermatitis. In the management of senile AD, changes related to aging process should be considered. Management of senile AD is complex, involves combined pharmacological treatment consists of topical and systemic agents, and non pharmacological aspects. Appropriate treatment considering effectiveness and safety will improve the quality of life of patients with senile AD.

Atypical mycobacterial infection resembles sporotrichosis in elderly patient Fauziah, Siti Nurani; Legiawati, Lili; Sularsito, Sri Adi; Yusharyahya, Shannaz Nadia; Rihatmadja, Rahadi; Sirait, Sondang P.; Huda, Fifi Mifta; Widyasari, Indah
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Atypical mycobacterial (AM) infection is caused by Mycobacterium species other than M.tuberculosis. AM skin infection has clinical manifestations that resemble M. tuberculosis infection and deep fungal infection. Laboratory workup is necessary to confirm the diagnosis. An 83-year old female came with a painful lump and swelling on her right lower extremity since three months before admission. Physical examination revealed a plaque consisting, of multiple erythematous and hyperpigmented papules and nodules, diffuse erythematous lesion, and shallow ulcers partially covered with pus and crust. Histopathological features showed tuberculoid granuloma. Direct test and periodic acid-Schiff (PAS) staining of the skin biopsy found no fungal element nor acid-fast bacilli (AFB). Culture and polymerase chain reaction (PCR)of M. tuberculosis were negative. The working diagnosis was atypical mycobacterial infection and treatment with 450 mg rifampicin and 100 mg minocycline daily were administered accordingly. In two months observation following the treatment, the pain was no longer exist, the ulcers were completely healed, and some nodules were in the process of healing Among other Mycobacterium spp, M.marinum is the most common cause of AM infrections. Clinical manifestation of M. marinum infection may present as solitary or multiple nodules on the hands, feet, elbows and knees with sporotrichoid spreading patern. The diagnosis of AM was established based on clinical and laboratory examination. The diagnosis was also confirmed by good clinical response to minocycline and rifampicin.

Venous Ulcer Santoso, Irene Dorthy; Nilasari, Hanny; Yusharyahya, Shannaz Nadia
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 2, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Leg ulcers one common problem in the adult population to geriatric with a prevalence about 1-2%. The pattern of life which tends to be sedentary, less activity, obesity, increased the incidence of leg ulcers. The duration of healing and recurrence occurs in majority of patients contributed the decline in quality of life for patients with venous ulcers. Diagnosis, latest treatment and prevention are essential to discuss.

Co-Authors Adhi Harmoko Saputro Adhika Ayu Lestari Adistri, Kara Aldri Frinaldi Andhira, Vega Barros, Terlinda Chandrakesuma, Vivianne Christine Lieana Devi Arofah Edwar, Sarah Qanita Eliza Miranda Endi Novianto Erdina Pusponegoro Evita Halim Effendi Evita Halim Effendi Eyleny Meisyah Fitri Fauziah, Siti Nurani Fifi Mifta Huda Githa Rahmayunita Halim, Dionisius Ivan Yonathan Hanny Nilasari Hapsari, Yari Castiliani Hartanto, David Dwiadiputra Huda, Fifi Mifta Ika Anggraini Ilyas, Nabila Chalisya Imelda Wihadi Inadia Putri Chairista Indah Widyasari Irawan, Yudo Irene Darmawan Irene Dorthy Santoso Irma Bernadette Irwan Saputra Batubara Jonlean, Reganedgary Kusmarinah Bramono Kusumawardhani, Dina Larisa Paramitha Lili Legiawati Lusiana Lusiana Lusiana Lusiana Marsha Bianti Martinus Tarina Martinus, Martinus Melody Febriana Andardewi Menaldi, Sri Linuwih Susetyo Wardhani Mutiara Ramadhiani Natalia Rania Sutanto Natalia Rania Sutanto Nugraheni Pasaribu, Uly Aanda Maria Prayogo, Rizky Lendi Priyanto, Mufqi Handaru Puteri, Fathirah Rahmatiah Putu Martha Gerynda Sukma Putu Siska Virgayanti Rahadi Rihatmadja Rahadi Rihatmadja Ratu Siti Khadijah Sarah Rheza, Agung Mohamad Rhida Sarly Amalia Rinadewi Astriningrum Rizky Lendl Prayogo Roro Inge Ade Krisanti Sampurna, Adhimukti T. Sandra Widaty Santoso, Irene Dorthy Sarah Qanita Edwar Sirait, Sondang Panjaitan Siti Nurani Fauziah Sitohang, Irma Bernadette S. Sondang P Sirait Sondang P. Sirait Sri Adi Sularsito Sri Adi Sularsito Sri Adi Sularsito Terlinda Barros Tiara Aninditha Valdi Ven Japranata Vivianne Chandrakesuma Widyasari, Indah Wihadi, Imelda Windy Keumala Budianti Wresti Indriatmi B. Makes Yudo Irawan Yudo Irawan

Title

Found 26 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 26 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 26 Documents
Search