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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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The effect of walking physical exercise on blood pressure of the pedestrian community in Penjaringan Sari Surabaya Akmal Zidan Alaudin; Gadis Meinar Sari; Yudi Her Octaviono
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.18710

Abstract

Hypertension is a non-communicable disease that is one of the main causes of premature death in the world. Pharmacologically by administering anti-hypertensive drugs. In non-pharmacological management of hypertension can be done with a healthy lifestyle. A study states that the most appropriate non-pharmacological treatment for people with hypertension is exercise. This research is quantitative research with a quasi-experimental design. The dependent variable in this study was walking physical exercise, while the independent variables in this study consisted of heart rate, systolic blood pressure, and diastolic blood pressure. The subjects of this study were 30 members of the pedestrian community, who were divided by purposive sampling into the treatment group and the control group. The tools used to obtain primary data in this study were the results of measuring blood pressure before and after walking. The results of the study: 1) there is a difference in the average pulse rate between the pretest and post-test in both the treatment and control groups; 2) there is an effect of walking physical exercise on pulse rate; 3) there is a difference in the mean systolic blood pressure and diastolic blood pressure between pretest and post-test; 4) there is a difference in the average blood pressure between the pretest and post-test of the control group; 5) there is no effect of physical exercise walking on blood pressure; 6) There was no difference in blood pressure and pulse between the treatment and control groups. In conclusion, the physical exercise of walking for 1 week could reduce pulse rate but could not reduce systolic blood pressure and diastolic blood pressure.
The effectiveness of giving Android-based applications as promotional media in improving COVID-19 preventive behavior in the community Ira Purnamasari; Ferry Effendy; Lailatun Ni’mah; Dede Nasrullah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.12829

Abstract

Public understanding of COVID-19 is the main focus to break the chain of spread. The massive spread of the virus shows the lack of public knowledge about preventing transmission. The best way to prevent and slow down transmission is to get information about COVID-19. There are still limited promotional media in providing health education in the community, especially Android-based applications. The purpose of this study was to determine the effect of giving an Android-based application as a promotional medium in improving COVID-19 prevention behavior in the community. This study used a pre-experimental research design with one group pre-test and post-test design. The population is all people in the Mulyorejo village amounted to 22.862 and taken samples of 193 people using a non-probability purposive sampling technique with the respondent criteria aged 31-45 years. The knowledge questionnaire consisted of 20 statements and the attitude questionnaire with 18 statements. The statistical test uses the Wilcoxon Signed Rank Test to find out differences in knowledge and uses the Chi-Square Test to find out differences in attitudes. The results of knowledge have increased from pre-test sufficient knowledge (52.8%) and post-test good knowledge (80.3%) using the Wilcoxon signed rank test p=0.000<0.05. The results of attitudes have increased from pre-test negative attitudes (63.2%) and post-test positive attitudes (76.2%) using the Chi-square test p=0.000<0.05. The conclusion is that there is an effect of giving Android-based applications as a promotional medium in improving COVID-19 prevention behavior in the community.
CRISPR-Cas9 through AAV delivery system as a gene therapy in Parkinson’s disease Maulana Bagus Adi Cahyono; Ilham Rahmanto; Zahras Azimuth Doman; Galuh Senjani Yulfani Putri; Christopher Surya Lodianto; Pradana Zaky Romadhon
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.16117

Abstract

The global population living with Parkinson’s disease is estimated to reach 9.4 million people, which has increased significantly since 2016, with a total of 6 million people. Parkinson's is a neurodegenerative disease of the substantia nigra that causes a decrease in dopamine production and is characterized by the appearance of cytoplasmic misfold proteins called Lewy bodies. The study found that abnormalities or mutations in the SNCA and LRRK2 genes correlated with the overproduction of the ɑ-synuclein protein, which forms Lewy bodies that cause Parkinson's. Current Parkinson's medications only temporarily replace lost dopamine but do not treat the direct cause of Parkinson's; this research used qualitative literature study with content analysis, observation, and development; the use of CRISPR-Cas9 through AAV genetic engineering in repairing SNCA and LRRK2 mutant gene. This genetic therapy works by cutting the mutant DNA base sequences in the SNCA and LRRK2 genes and then replacing them with normal sequences through a homology-direct repair mechanism. As a result, the abnormalities or mutations that cause Parkinson's in these two genes can be corrected, so that dopaminergic levels in the brain can return to normal and excessive accumulation of α-synuclein protein can be suppressed.
Wide excision of Basal Cell Carcinoma on the upper extremity: A case report Maylita Sari; Putri Halla Shavira; Bagus Haryo Kusumaputra; Irmadita Citrashanty; M Yulianto Listiawan
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.15495

Abstract

Basal cell carcinoma (BCC) is the most common skin cancer, usually occurring in the sun-exposed area, such as the head and neck, but also seen in less common areas like the upper or lower extremities. The initial treatment of BCC lesions is completing tumor removal. One of the standard therapy for BCC is wide surgical excision, as it is highly efficacious. A 76-year-old female patient complained of a wounded blackish lump on the left upper extremity for about 2 years. It started small, then grew bigger. Complained of itchiness, but no pain. The lump easily bled when accidentally touched. Dermatology examination identified a hyperpigmented nodule about 1.5 cm, with a clear border, irregular raised edges, slightly rough surface, and erosion. A dermoscopy examination showed short-fine telangiectasia, blue-grey ovoid nests, and ulceration. The patient was diagnosed with suspected BCC and underwent biopsy, also wide excision surgery. Histopathology showed pigmented BCC. One month later, surgery proved a good result. Selecting appropriate therapy in BCC should be given to reduce the recurrence rate. The common treatment for BCC is wide surgical excision, because of its association with a low recurrence rate and the ability to confirm residual tumor pathologically. In conclusion, wide excision surgery is one of the effective therapy options for BCC.
An overview of anxiety levels of Muhammadiyah citizens against COVID-19 vaccination in Surabaya Siti Aisyah; Ira Purnamasari; Uswatun Hasanah; Dede Nasrullah; Vika Ramadhana Fitriyani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.14450

Abstract

Since the publication of PERMENKES Number 10 of 2021 on the implementation of vaccinations in the context of the COVID-19 pandemic, the community, particularly Muhammadiyah residents, has responded. Most Muhammadiyah residents do not have anxiety about COVID-19 vaccination because people are starting to realize the importance and benefits of vaccination. Even though vaccination activities have been going on for a long time, there are still people who feel anxious about the COVID-19 vaccination. The anxiety experienced by respondents is a natural thing because the current pandemic is a new type of disease that has never been experienced before. Numerous media outlets produce a lot of news that has the potential to change how the public feels about vaccines. Anxiety can be brought on by the general public's poor impression of immunizations. The process of immunizing will be hampered by the onset of fear. The study aimed to describe the amount of COVID-19 vaccination-related anxiety among Muhammadiyah inhabitants in Surabaya. This study, a descriptive study with 100 respondents, used probability sampling using a stratified random sampling technique. The DASS-42 questionnaire was utilized as the data-gathering tool. The findings revealed that 77 persons (77 percent) and 23 people did not experience any abnormal levels of vaccination fear (23 percent). According to the study's findings, the majority of Muhammadiyah inhabitants did not experience fear related to receiving a COVID-19 immunization since people were starting to understand the significance and advantages of vaccination. Although COVID-19 immunization campaigns have been ongoing for a while, some people still experience anxiety. Respondents' fear is understandable given that the present epidemic is a brand-new disease that has never been seen before.
Relationship between personality traits and perinatal depression at Muhammadiyah Hospital Surabaya Ninuk Dwi Ariningtyas; Putri Aqila; Era Catur Prasetya; Roni Subagyo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.17634

Abstract

Perinatal depression is a feeling disorder that occurs in a woman during pregnancy and after childbirth. Perinatal depression can be seen from various factors, one of which is personality traits. This study aims to determine the relationship of personality traits with perinatal depression at Muhammadiyah Hospital Surabaya. This study was observative analytic using a cross-sectional approach, conducted on 96 respondents using the Edinburgh Postnatal Depression Scale (EPDS) and the OCEAN personality trait questionnaire. The result of the multiple linear statistical tests on the F test is p=0.00 (p<0.05), the t-test on the extraversion personality trait is p=0.031 (p<0.05), and the neuroticism personality trait is p=0.000 (p<0.05). The coefficient of determination test R2= 37.0%. In conclusion, there is a relationship between personality traits and perinatal depression at Muhammadiyah Surabaya Hospital.
Partial Rotator Cuff Tear outcome between prolotherapy with physical rehabilitation compared to physical rehabilitation only: A Meta-analysis approach Galuh Ayu Ratna Savitri; Thomas Erwin Christian Junus Huwae
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.15693

Abstract

Partial Tear Rotator Cuff Tendinopathy (PTRCT) impacts 15% to 50% of the population and increases in prevalence with individuals' age. Several first-line management strategies for treating rotator cuff disease, such as physical rehabilitation and/or injection, have been reported. However, optimum management is debatable. This study aims to explore the outcome management combination of prolotherapy and physical rehabilitation with physical rehabilitation only for PTRCT. Randomized Control Trial (RCT) studies From PubMed, Cochrane Library, ScienceDirect, ProQuest, And Google Scholar were included. Two independent reviewers evaluated the quality of RCTs using the Cochrane Risk of Bias Tool. The primary result was pain reduction, with functional improvement as a secondary outcome. Meta-analysis was performed using Review Manager 5.4 software. Our meta-analysis included 5 RCT studies involving 263 patients. Standardized mean difference (SMD) was collected from all of the studies. In this study, pain reduction was significantly decreased in the prolotherapy group compared with physical rehabilitation only during 12 weeks follow-up (-0.97 (95% -1.63 to -0.31) with p: 0.0004) and obtained I2 57 % that, representing moderate heterogeneity. In contrast, Functional improvement did not significantly reduce (-1.04 (95% -5.45 to 3.317) with p: 0.64. In conclusion, Prolotherapy with physical rehabilitation can reduce pain in long-term (12 weeks) patients with PTRCT compared to physical rehabilitation only but give no significant effect in improving functional outcomes.
Ocular manifestations in COVID-19 Patients at Dr. Wahidin Sudiro Husodo General Hospital Mojokerto during January – June 2021 Rini Kusumawar Dhany; Gusti Ratu Azzahra
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.17356

Abstract

Coronavirus Disease (COVID-19) is a respiratory infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 can be found in ocular organs through direct inoculation, migration via the nasolacrimal duct, or hematogenous. This study aims to determine the clinical manifestations of eye disease in COVID-19 patients at Dr. Wahidin Sudiro Husodo Mojokerto General Hospital from January-June 2021. A cross-sectional retrospective observational study by collecting secondary data on patient medical records. The research sample was all outpatients and inpatients with a positive PCR test for COVID-19 who were consulted by an ophthalmologist at Dr. Wahidin Sudiro Husodo General Hospital Mojokerto in January-June 2021. A total of 861 cases of patients with positive PCR tests for COVID-19, a total of 67 patients were consulted to eye specialists with a median age of 42.6 years. Among 67 patients, 59 (88%) showed symptoms of conjunctival injection, 8 patients (12%) ciliary infusion with 7 patients diagnosed with keratitis, and 1 patient with ulcer redness. In conclusion, the main eye manifestation most commonly found in COVID-19 patients is conjunctivitis which is characterized by conjunctival hyperemia.
Differences score between online and offline laboratory sessions of parasitology in Medical Faculty Atika Widyaningrum; Mega Pandu Arfiyanti; Kanti Ratnaningrum
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.12368

Abstract

Capabilities to diagnose diseases caused by parasites is one of the competencies that must be mastered by general practitioners. This is stated in Standar Kompetensi Dokter Indonesia (SKDI). The branch of parasitology includes protozoa, helminths, and arthropods. Competency can be achieved through debriefing activities and laboratory sessions. During the pandemic, laboratory sessions of parasitology are carried out online with modification of implementation techniques. The study aims to determine the differences in scores between online and offline laboratory sessions of parasitology in medical faculty. Quantitative research used a quasi-experimental method, with a simple random sampling technique. The research data used secondary data scores of laboratory sessions of helminth and protozoa parasitology of Medical students in Universitas Muhammadiyah Semarang (Unimus). Data were analyzed by using a non-parametric Mann-Whitney u-test. From 62 students, there were significant differences in scores between online and offline helminth laboratory sessions (p=0.00) with the average scores of online helminth courses higher than offline laboratory sessions (70.6±19.8). There was no significant difference in grades of online and offline protozoa laboratory sessions (p=0.576) with average scores of online protozoa courses being lower than the offline laboratory session (55.8±25.5). There is a significant difference in scores between the helminth laboratory session of parasitology and there is no difference in scores between the protozoa laboratory session in Medical Faculty.
Seroprevalence of Galactomannan Aspergillus in COVID-19 patients in Jakarta: A challenge in the pandemic commotion Anna Rozaliyani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.19153

Abstract

COVID-19-associated pulmonary aspergillosis (CAPA) is a severe complication of COVID-19 due to Aspergillus infection. However, the clinical manifestation and radiology findings are not typical and require measurement of Aspergillus galactomannan (GM) level to assist in the diagnosis of CAPA. We evaluated the positivity rate of Aspergillus GM level among COVID-19 patients and investigated the correlation between the GM level and the age of patients. This retrospective observational study compiled the GM results from COVID-19 patients’ sera during the early period of the COVID-19 pandemic from March 2020 to December 2021. All samples underwent an ELISA test to measure Aspergillus GM level. There were 96 patients enrolled in this study. The positivity rate was 33%, with the highest (56%) percentage of positivity observed in the age group 40-59 in the positive Aspergillus GM group. The measurement of Aspergillus GM level among COVID-19 patients with risk factors of CAPA is critical to establish CAPA diagnosis. The availability of Aspergillus GM test in Indonesia is still limited and this issue needs to be addressed by all healthcare experts and stakeholders.

Page 18 of 31 | Total Record : 301

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