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INDONESIA
Al-Kimia
ISSN : 23022736     EISSN : -     DOI : -
Core Subject : Science,
Al-Kimia is a journal of chemistry that published by Department of Chemistry, Faculty of Science and Technology UIN Alauddin Makassar. The journal is published twice a year on January-June and July-December. This journal encompasses original research articles in all aspects of chemistry and related area. The journal, which was firstly published in July 2013, is a forum for communication of research results, review the results of research, methodologies and new approaches in research related to chemistry in Indonesia.
Arjuna Subject : -
Articles 238 Documents
Enkapsulasi Urea Menggunakan Biokomposit Zeolit Alam-Alginat-Pati Sagu sebagai Model Pupuk Lepas Lambat (Slow Release Fertilizer) Ida Ayu Suci; Ismail Astar
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.23739

Abstract

The urea fertilizer was encapsulation with the compositions of natural zeolite-alginate-sago starch biocomposite for developing of slowed-release properties. The characteristics of biocomposites such as FTIR, SEM, and nitrogen release tests were evaluated. Fourier transform infrared spectroscopy showed the presence of natural zeolite-alginate-sago starch biocomposite. The SEM images showed the surface morphology of urea has been coated by natural zeolite-alginate-sago starch biocomposite. Nitrogen release tests on natural zeolite-alginate-sago starch biocomposites with concentrations of 20% was the composition with the best results in holding urea encapsulated. This study indicates that natural zeolite-alginate-sago starch biocomposites are a alternative candidate for the development of the efficient slowed-release formulation of urea.
Enkapsulasi Urea Pada Lumpur PDAM-Alginat sebagai Pupuk Lepas Lambat Ismail Astar; Ida Ayu Suci
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.23740

Abstract

Modification of sludge solid waste regional water company (PDAM) Pontianak with alginate for the application of slow-release urea fertilizer. Characterization of materials was performed with Fourier-Transform Infra-Red (FTIR) spectroscopy and scanning electron microscopy (SEM). Analysis of the FTIR spectrum obtained showed that the characteristics of the absorption band at wavelengths of 3639.89 cm-1 and 3690.9 cm-1 are characteristic of the vibration of NH2 stretching asymmetric and symmetric derived from the presence of urea. Nitrogen release tests on mud PDAM-alginate composites with concentrations of 10%, 20%, 30%, 40% and 50% for 72 consecutive hours of 12,80%, 19,33%, 4,00%, 8,39% and 6,20%. This shows that urea encapsulated mud PDAM-alginate at a concentration of 30% is the composition with the best results in holding urea encapsulated.
In Vitro Anti-inflammatory Activity of Extract and Fraction Seed Coat Kebiul (Caesalpinia bonduc L.) Raden Fatahillah; Dwi Fitriyani; Fitria Wijayanti
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.23769

Abstract

Inflammation is the protective reaction of body and supporting element of tissues to injurious stimuli, such as physical injury, tissue and cell damage by pathogens, and protein denaturation. This study aims to compare the antiinflammatory activity of ethanol extract, ethanol fraction, and n-hexane fraction from kebiul (Caesalpinia bonduc L.) seed coat. Antiinflammatory activity was tested by measuring the % inhibition of the denatured protein using a UV-Vis spectrophotometer. From the result of the study obtained IC50 value 2,10 μg/mL, 7,89 μg/mL, 4,04 μg/mL & 11,03 μg/mL.
Identifikasi Komponen Kimia Ekstrak Daun Ketapang (Terminalia cattapa) Berdasarkan Perbandingan Metode Ekstraksi Ismail Marzuki; Melisa Mirsyah; Selfina Gala
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.25457

Abstract

Screening, characterization and identification of chemical components of typical Indonesian plants are important for the purpose of finding high potential chemical components in the use of primary sources of cosmetic, medicinal and food ingredients. The selection of the right extraction method and the appropriate type of solvent is very decisive in the acquisition of the target chemical components. The brand of this research focuses on the comparison of extraction between soxhletation and maceration methods in identifying the chemical components of Ketapang leaves (Terminalia Catappa). Sample preparation was carried out by selecting fresh, cleaned, dried and mashed Ketapang leaves. The extraction was carried out in two stages using two types of solvents, namely the first stage of extraction using ethanol. Obtained a dilute extract, then concentrated using a rotary evaporator. The second extraction used n-hexane as solvent. There are 4 kinds of extracts, each ethanol extract and n-hexane extract by applying the soxhletation and maceration method. The results obtained showed that: the application of the maceration method to the identification of chemical components of ketapang leaves gave relatively better separation results than the soxhletation method. The number of chemical components identified from the ethanol extract of ketapang leaves is ± 20 species which are dominated by fatty acid compounds. There are two groups of chemical compounds identified from ketapang leaves using n-hexane as solvent both in the application of soxhletation and maceration methods with high similarity 90%, namely 4 kinds of chemical components of the fatty acid group (tetradecanoic acid, Hexadecanoic, Octadecanoid, Octadeca-9,12 -Dienoite) and 2 kinds of aliphatic components (methyl cyclopentane, Tetraco Hexane)
Enkapsulasi Asap Cair Tandan Kosong Kelapa Sawit (Elaeis guineensis Jacq.) dan Uji Aktivitas Antijamur Riskawati; Nurul Magfira; Maswati Baharuddin; Sappewali; Fitria Azis
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.25723

Abstract

Oil palm empty bunches is lignocellulose that can be processed into liquid smoke with the content of acid compounds and phenol compounds that function as a natural preservative. The purpose of this study to find out the characteristics of liquid smoke, see the effect of encapsulan on the liquid smoke encapsulation process, and see the antifungal activity of A. flavus and A. niger. The method used is pyrolysis process at a temperature of 400 oC to produce liquid smoke and encapsulation process by using variation of coating material using spray dryer with micro sized result. The result showed that the liquid smoke characteristics can be seen from its chemical content that is the dominant phenol compound and has the highest phenol content among the parts found in oil palm that is 68,15%. Based on analysis it can be seen that the best encapsulation process is by the addition of chitosan on maltodextrin with water content 5.78%, phenol content of 43.03 ppm and has a high rate of encapsulation efficiency of 45.87%. The liquid smoke microcapsules could inhibit the growth of fungi with the highest value of liquid smoke concentration, that is 3% with inhibitory value of 8.30 mm.
Uji Aktivitas Antioksidan Ekstrak Buah Srikaya (Annona Squamosa L.) Muda dan Matang dengan Metode FRAP (Ferric Reducing Antioxidant Power) Haekal Wahyudi; Adlim; M. Nasir
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.27391

Abstract

The antioxidant activity test of young and ripe Srikaya fruit extract (Annona Squamosa L.) had been carried out by using the FRAP (Ferric Reducing Antioxidant Power) method. This study aims to determine the antioxidant activity of young and ripe srikaya fruit extract using the FRAP method by using qualitative and quantitative method. The research method used was FRAP (Ferric Reducing Antioxidant Power) which was based on a reduction reaction in an acid state towards a yellow Fe3+ (Potassium hexacyanoferat(III)) complex compound to become a bluish-green Fe2+ complex compound due to electron donors from antioxidant compounds. The result of the qualitative analysis of the antioxidant activity of young and ripe srikaya fruit extract was a change in color in the sample extracts of young and ripe Srikaya fruit due to the reduction reaction in an acid state towards the yellow-colored Fe3+ (Potassium hexacyanoferat(III)) complex compound to become a bluish-green Fe2+ complex compound. due to electron donor of antioxidant compounds. Quantitatively, the average antioxidant activity of samples of young and ripe srikaya fruit extract was respectively 7,448 mgAAE/g extract and 9,351 mgAAE/g extract. The result indicated that the antioxidant activity of ripe srikaya fruit was greater than that of young fruit. Based on the results of the analysis parameter testing the t-test, it can be concluded that there is a significant difference in the antioxidant activity of the young and ripe srikaya fruit extract (Annona squamosa L.). The antioxidant activity test of young and ripe Srikaya fruit extract (Annona Squamosa L.) had been carried out by using the FRAP (Ferric Reducing Antioxidant Power) method. This study aims to determine the antioxidant activity of young and ripe srikaya fruit extract using the FRAP method by using qualitative and quantitative method. The research method used was FRAP (Ferric Reducing Antioxidant Power) which was based on a reduction reaction in an acid state towards a yellow Fe3+ (Potassium hexacyanoferat(III)) complex compound to become a bluish-green Fe2+ complex compound due to electron donors from antioxidant compounds. The result of the qualitative analysis of the antioxidant activity of young and ripe srikaya fruit extract was a change in color in the sample extracts of young and ripe Srikaya fruit due to the reduction reaction in an acid state towards the yellow-colored Fe3+ (Potassium hexacyanoferat(III)) complex compound to become a bluish-green Fe2+ complex compound. due to electron donor of antioxidant compounds. Quantitatively, the average antioxidant activity of samples of young and ripe srikaya fruit extract using the FRAP method was respectively 7,448 mgAAE/g extract and 9,351 mgAAE/g extract. The result indicated that the antioxidant activity of ripe srikaya fruit was greater than that of young fruit. Based on the results of the analysis parameter testing the t-test, it can be concluded that there is a significant difference in the antioxidant activity of the young and ripe srikaya fruit extract (Annona squamosa L.).
Production, Purification and Characterization of Cellulase from Cossus cossus Larvae Maswati Baharuddin
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.28071

Abstract

This study aimed to purify and characterize the biochemical properties of cellulase from bacterial isolates of C. cossus larvae, to determine the effect of adding crude extract cellulase and pure enzymes to the hydrolysis of rice straw. The research steps included purification of enzymes by ion exchange chromatography and gel filtration chromotography, as well as SDS-PAGE electrophoresis analysis. Pure cellulases are characterized by their biochemical properties and applied in the hydrolysis of cellulose. The results showed that the characteristics of an optimum pH of 5.6, an optimum temperature of 70⁰C and a substrate concentration of 1.5% CMC, and a molecular weight of 36.49 kDa.
Treatment Palm Oil Mill Effluent (POME) Using Continuous Column Plate Electric Reactor Susanto, Reno; Aulia Rahmi , Viona; Widyaningsih , Dwi
Al-Kimia Vol 10 No 2 (2022): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i2.25646

Abstract

Palm oil mills produce palm oil mill effluent (POME) which contains various dissolved organic compounds in the form of short fibers, hemicellulose, and their derivatives, protein, free fatty acids, a mixture of minerals and organic pigments such as anthocyanins, carotene, polyphenols, lignin and tannins. Organic compounds in this waste will cause problems such as increasing the value of TSS, TDS, and COD which can be a crucial environment for processing liquid waste in palm oil mills. One possible method to reduce the content of TSS, TDS, and COD is the electrocoagulation method. This study aims to determine the effect of variable flowrate, voltage, and distance between plates in the electrocoagulation process with a plate column electric reactor, and determine the optimum conditions for flowrate, voltage, and distance between plates. Optimum conditions are obtained at fflowrate3 L/min, 28 V voltage, 2 cm distance between plates with percent removal of TSS, TDS, and COD, respectively 49.30%; 49.40%; 60.30%.
Molecular Docking of Michelia alba Leaves Active Compounds Against Human Epidermal Growth Factor Receptor 2 (HER-2) Isman, Felysia; Pratama, Paundra; Fadlan, Arif
Al-Kimia Vol 10 No 2 (2022): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i2.28437

Abstract

Breast cancer characterized by overexpression of the human epidermal growth factor receptor-2 (HER-2) and is a deadly disease worldwide. Chemotherapy with drugs targeting HER-2 is less effective and shows various drawbacks. This study aimed to study anticancer potential of active compounds contained in Michelia alba through molecular docking against HER-2. The molecular docking study was performed toward HER-2 receptor (PDB: 3PP0) containing 30Q native ligand with MCULE. The results showed that cis-linalool oxide, trans-linalool oxide, linalool, β-elemena, α-humulene, and nerolidol contained in M. alba leaves had lower docking scores than quercetin as control. Nerolidol showed the lowest docking score among all compounds. The active compounds in the leaves of M. alba have the potential as a HER-2 inhibitor in silico.
Potential of Secang Wood (Caesalpinia sappan L.) Ethanol Extractas Anti-Oxidant and Sun-Protection Hafshah, Mutista; Rohmah, Alfiatu; Mardliyah, Ana
Al-Kimia Vol 10 No 2 (2022): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i2.28619

Abstract

Although sunlight has numerous health benefits, prolonged direct exposure to the sun can be harmful to the skin. Among the negative effects of sun exposure are redness and burning of the skin, as well as dullness, wrinkles, dryness, and premature aging, as well as skin cancer. The use of sunscreen to protect the skin from the harmful effects of prolonged sun exposure is becoming more widespread. On the other hand, some sunscreens contain potentially harmful chemicals such as isopropyl alcohol, DEA (diethanolamine), TEA (triethanolamine), and MEA (monoethanolamine), which can cause allergic reactions as well as kidney and liver disorders when used for an extended period of time. As a result, this investigation was carried out in order to determine the antioxidant potential of natural ingredients, specifically sappan wood (Caesalpinia sappan L.), using the DPPH method, as well as its potential as a sun-protective agent using an in vitro SPF test using ultraviolet-visible (Uv-Vis) spectrophotometry (Uv-Vis). The results revealed that the maceration method produced a 17.779 percent yield of ethanol extract of sappan wood, which was used in this study. The extract possesses extremely potent antioxidant activity, as evidenced by its IC50 value of 12,611 mg/L. Furthermore, based on the results of tests and the calculation of the SPF (sun protection factor) value, sappan wood extract has been shown to have potential as a sun protection agent. Using an extract concentration of 120 mg/L, the highest SPF value.