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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
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Articles 10 Documents
Search results for , issue "Vol 16, No 1" : 10 Documents clear
Ivabradine in Heart Failure with Reduced Ejection Fraction (HFrEF): A Narrative Review of Clinical Outcomes Hidayaturahmah, Rizky; Khoerunisa, Erin; Suprahman, Nisa Yulianti; Novitasari, Fia
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.88590

Abstract

Background: Therapy for heart failure with reduced ejection fraction (HFrEF) patients is complex, involving several combinations of treatments, but there are still some problems, such as rehospitalization, reduced ejection fraction values, increased heart rate, and decreased quality of life. Ivabradine, a selective heart rate-lowering agent, offers adjunctive therapeutic benefits.Objective: This study aims to determine the characteristics of HFrEF patients who received additional therapy with ivabradine and to determine how ivabradine affects their clinical outcomes.Methods: This narrative review searched articles on PubMed, Cochrane Library, Google Scholar, and ScienceDirect. The research was limited to randomized controlled trial articles, observational studies, and cohorts with international and national English and/or Indonesian articles published in the last 10 years.Results: Twenty-eight studies (n=36,765) met the problem formulation and inclusion criteria were analyzed. Patients receiving ivabradine were predominantly male (74.9%), aged 56-65 years (81.9%), and had a history of smoking. Most patients had heart rate ≥70 bpm (75.4%), LVEF ≤30% (55.3%), BMI ≥28 kg/m² (87.1%), and NYHA class II-III (85.5%). The addition of ivabradine to the clinical outcome of HFrEF patients reduces heart rate (15.7 bpm), blood pressure (SBP: -4.4 mmHg; DBP: -0.9 mmHg), rehospitalization, and mortality, while improving LVEF and stroke volume, and quality of life. Adverse effects included manageable bradycardia and transient visual disturbances.Conclusion: Ivabradine effectively improves clinical outcomes in HFrEF patients as adjunct therapy, with significant benefits in cardiac function, symptom control, and prognosis.
Pharmacists’ Ability in Recognising and Managing Angiotensin Converting Enzyme Inhibitor (ACEI)-Induced Cough in Self-Medicating Patients Brata, Cecilia; Wibowo, Yosi Irawati; Setiawan, Eko; Halim, Steven Victoria; Razanah, Afina; Sholikhah, Ima Mar’atus; Lailla, Putri Rohmatu; Rahmadini, Azilah; Putri, Ida Ayu Elsa Ratu Satwika; Irawati, Lyna
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.96432

Abstract

Background: As ACEIs are widely used and patients with cough often self-medicate at community pharmacies, pharmacists must be able to recognise ACEI-induced cough and refer patients appropriately. However, literature on pharmacists’ ability to manage ACEI-induced cough is limited.Objectives: This study aims to describe pharmacists' ability to recognise and manage a vignette case of ACEI-induced cough in self-medicating patients.Methods: This cross-sectional study was conducted in community pharmacies across a metropolitan city in Indonesia. All pharmacies were visited and pharmacists who were available and willing to participate were interviewed by five trained data collectors. An open-ended questionnaire featuring a vignette of ACEI-induced cough was used. Pharmacists were asked to provide their recommendations for the case and explain their reasoning. Responses were analysed using content analysis, involving systematic coding and categorisation of the textual data to identify underlying patterns and themes.Results: Of 245 participating pharmacists, 189 (77%) could recognise that the cough was due to ACEI. However, only 101 of these 189 participants could provide an appropriate response (i.e., direct medical referral without recommending a product to treat the cough and/or changing or stopping the ACEI).  Conclusion: While many pharmacists may possess the necessary knowledge to recognise ACEI-induced cough in the case of a self-medicating patient, they may lack sufficient knowledge about the appropriate response of this problem. Educational intervention is needed to improve pharmacists’ knowledge and ability to manage an ACEI-induced cough case.
Study of Antihypertensive and Antiplatelet Use in Outpatient Preeclampsia Patients at Siti Khodijah Sepanjang Hospital Purwanti, Uchti Firda; Fandinata, Selly Septi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.98249

Abstract

Background: Preeclampsia is a complication of pregnancy characterized by increased blood pressure and the presence of proteinuria after reaching 20 weeks of gestation. Besides that, the diagnosis of preeclampsia can be reinforced by other symptoms such as edema, impaired liver and kidney function.Objectives: This study aims to investigate the usage of antihypertensive and antiplatelet medications in outpatient preeclampsia patients at Siti Khodijah Sepanjang Hospital from January 2022 to December 2023.Methods: Data collection method is retrospective, obtained from medical records of 70 preeclampsia patients. The sampling technique using purposive sampling method according to the inclusion research criteria. Data was analyzed using Microsoft Excel 2021.Results: Data on drug usage profiles obtained during the treatment, shows that the most common combination is a combination of two antihypertensive drugs and an antiplatelet, namely metildopa (category B) + aspirin (category C), with a dosage of 500 mg + 80 mg per day. The medication regimen is S2dd1 + S1dd1, and the average duration of treatment ranges from 7 to 30 days. With this treatment, the blood pressure of preeclampsia patients experienced a change in the patient's blood pressure which decreased in 65 patients with the initial classification of mild preeclampsia being 54 patients to normal in the final preeclampsia classification of 56 patientsConclusion: This study provides several important implications for health workers in Indonesia in the management of preeclampsia disease with the use of antihypertensive and antiplatelet drugs, so that they can provide services that are in accordance with the medical needs of patients.
Potential Antibiotic-Drug Interactions: Analysis of Pediatric Patient Prescriptions at Omnia Farma Pharmacy Purwokerto Utami, Esti Dyah; Maharani, Farah Ayu; Ekowati, Heny; Suryoputri, Masita Wulandari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101427

Abstract

Background: The use of drugs in pediatric patients requires special attention because pediatrics have physiological and anatomical differences with adults. Children are more susceptible to infectious diseases and often get antibiotic therapy and other symptomatic drugs to support recovery, thus increasing the potential for drug interactions.Objectives: The study aimed to analyze the incidence of potential antibiotic drug interactions prescribed to pediatric patients at Omnia Farma Pharmacy Purwokerto. Methods: This observational study was conducted retrospectively by collecting prescription data of pediatric patients aged 0-18 years at Omnia Farma Pharmacy Purwokerto from January to December 2023 using a simple random sampling method. Data were analyzed descriptively using the standard of the Lexicomp Interaction Checker database and other scientific literature. Results: There were 286 patient prescriptions that met the inclusion criteria. The majority of patients were male, aged 1-5 years, with the most prescribed antibiotic being amoxicillin (73.13%). The study only found potential drug interactions in 12 antibiotic prescriptions (4.20%), of which 50% were interactions between azithromycin and salbutamol. Most of the potential antibiotic-drug interactions found were of minor severity (91.67%), with pharmacodynamic interaction mechanisms (83.33%).Conclusion: The antibiotic prescriptions given to pediatric patients at Omnia Farma Pharmacy were quite good in terms of the minimal number of potential drug interactions found. Special attention to the therapy of pediatric patients through the collaboration of doctors and pharmacists is important to help patients get optimal therapy.
Pharmaceutical Management in Response to Natural Disasters: A Systematic Literature Review Nurlita, Diah; Satibi, Satibi; Widayanti, Anna Wahyuni; Alim, Syahirul
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101622

Abstract

Background: Problems still occur regarding pharmaceutical supplies management in overcoming natural disasters, such as excess stock, slow distribution, staff knowledge about emergency response, logistics systems, inappropriate pharmaceuticals for the disaster type, and cross-sector coordination.Objectives: This is a systematic review of natural disasters. The results are hoped to provide recommendations to improve pharmacy management responses.Methods: Research on pharmaceutical management at natural disaster sites, covering all phases of the management process from pharmaceutical selection to disposal, original research that is fully accessible, and those published in English within 2019-2024, are the conditions for inclusion. Duplication of publications is the exclusion criteria. Databases were searched for information about pharmaceutical management for natural disasters, such as Crossref, Science Direct, PubMed, Research Gate, and Google Scholar. This study'squality assessment applied the JBI CAT checklist, and was thematically synthesized.Results: Six studies were included in the total of59.794 identified studies. The relevant characteristics of the studies are related to pharmaceutical management scope, specifically the Drug Management Cycle.Conclusion: This study concludes that pharmaceutical management in dealing with natural disasters focuses more on aspects of planning, distribution, and management support when disasters occur.  The limitation of this review is the lack of research on the scope of storage, recording and reporting, evaluation, and disposal of pharmaceuticals.
Patients' Perception of Waiting Time and Pharmacy Service of Hospital X Bali Antari, Ni Putu Udayana; Megawati, Fitria; Suwantara, I Putu Tangkas; Palguna, I Gede Rizky; Widnyani, Ni Kadek Indah Amelia; Wahyuni, Ni Wayan Mita Sri
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101783

Abstract

Background: Many hospitals are having problems with waiting times. Meanwhile, the effect of waiting time on perceived pharmacy service quality is inconsistent. Waiting time and pharmacy service quality can influence a hospital's image through patient perception.Objectives: To identify factors influencing patients' perceptions of waiting time and pharmacy service quality.Methods: The study used a cross-sectional design with one hundred samples, which were taken using the convenience sampling method. Data were collected using questionnaires and direct observation at Hospital X and analyzed using SPSS version 26 in a 95% CI.Results: Actual and patient-perceived waiting times differed significantly (Wilcoxon test, P-value 0.005). Age significantly affected patient perceptions of pharmacy service quality in both bivariate and multivariate tests (Chi-square: P-value 0.032; Logistic regression: P-value 0.023, adjusted OR: 2.594 (Min: 1.138; Max: 5.912)). Even though included in the equation, the actual waiting time is not significantly associated with patient perceptions.Conclusion: Patients did not perceive waiting times in accordance with the actual waiting time because emotional factors easily influence the perception of time. Pre-elderly and elderly patients at Hospital X perceive pharmacy services dominantly as good quality. Age significantly influences patients' perception of pharmacy service quality. Actual waiting time may influence patients' perception of pharmacy service quality if other factors are controlled. Hospitals should consider age and emotional factors when waiting for services to maintain patients' good perceptions of pharmacy service.
The Association Between Medication Adherence and Drug-Related Problems (DRPs) with Clinical Outcomes of Diabetes Patients at Public Health Center in Salatiga Hati, Anita Kumala; Yasin, Nanang Munif; Kristina, Susi Ari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.104444

Abstract

Background: Diabetes mellitus (DM) is a disease whose clinical condition can be controlled. The clinical outcomes of DM patients are an important parameter for successful treatment and are influenced by many factors.Objectives: This study aimed to analyze the relationship between medication compliance and drug-related problems (DRPs) with the clinical outcomes of diabetes patients at three Primary Health centers in Salatiga.Methods: An observational study method was adopted with prospective data collection from the medical records and medication compliance observation of type 2 diabetes mellitus (T2DM) patients, in October 2023–April 2024. DRP analysis was based on categories Cipolle, 2012, and medication compliance was measured using the pill count method. Data analysis was conducted using the Spearman test to assess the correlation between medication adherence and HbA1c levels, as well as the occurrence of DRP.Results: A total of 40 subjects participated in this study, with the largest gender being female (72.5%), and hypertension was the most common comorbid condition (55%). The highest compliance rate in patients was 40% and DRP events were detected in 107 cases. The difference in patient HbA1c levels at baseline and the 3rd month showed a significant difference, and 67.5% experienced an increase. Furthermore, there was a strong relationship between compliance and HbA1c achievement (sig = 0.003, r = 0.452), as well as between the incidence of DRP and HbA1c achievement (sig = 0.000, r = 0.644).Conclusion: Compliance and DRPs influenced the HbA1c levels of T2DM patients in PROLANIS across three Public Health Centres in Salatiga.
Assessment of Prescribing Practice for Caesarean Section : Adherence to the Indonesian National Formulary Nurmainah, Nurmainah; Arfida, Khaizurani; Ulfah, Ridha
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.104754

Abstract

Background: The increasing prevalence of Caesarean Section (SC) deliveries and non-compliance with the National Formulary can lead to financial burdens for hospitals due to claim failures and higher drug costs. Understanding this relationship is crucial for improving cost efficiency and ensuring sustainable healthcare financing.Objectives: This study aims to analyse the percentage of prescribing compliance with the National Formulary and its impact on pharmacotherapy costs and the real costs of SC treatment at RSUD Dr. Soedarso.Methods: This research is an observational study with a cross-sectional design. Used medical record data of mild severity SC patients for the period January-December 2023. The sample consisted of 472 patients selected by purposive sampling. Descriptive Analysis and Spearman correlation were used to evaluate the relationship between prescribing compliance, pharmacotherapy cost, and real cost.Results: Adherence to the national formulary (97.10%). Spearman’s correlation analysis shows a significant negative correlation between adherence and pharmacotherapy costs. However, adherence has no significant correlation with total treatment costs, suggesting that factors like length of stay play a greater role.Conclusion: A significant negative correlation exists between compliance and pharmacotherapy cost, but no significant correlation with real costs. Future research should explore the relationship between total treatment costs and Length of Stay (LOS).
Translation and Validation of the Indonesian Version of Oral Chemotherapy Adherence Scale (OCAS) Puspitasari, Atika Wahyu; Kristina, Susi Ari; Satibi, Satibi; Prabandari, Yayi Suryo
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.105128

Abstract

Background: Medication adherence is essential for oral anticancer agents (OAAs) to succeed and maintain the optimal therapeutic outcomes. However, there are no well-established instruments in Indonesia to evaluate adherence to oral chemotherapy by cancer patients.Objectives: This study aimed to validate and translate the Oral Chemotherapy Adherence Scale (OCAS) for cancer patients in Indonesia.Methods: Data were collected from patients taking oral chemotherapy for at least a month at Dharmais Cancer Hospital in Jakarta. OCAS was translated into Indonesian using a forward-backward translation method. Content validity was assessed through expert review to calculate Content Validity Index (CVI), while face validity was evaluated to confirm cultural relevance and readability. Internal consistency was measured using Cronbach's alpha.Results: A total of 131 patients participated from August to December 2021. Content validation by seven experts showed that the mean I-CVI of the items was above 0.79, with an S-CVI of 0.985, reflecting the validity of the items. Furthermore, face validity confirmed the readability and clarity of Indonesian version of OCAS. Reliability testing showed a Cronbach alpha of 0.871, suggesting strong internal consistency.Conclusion: Indonesian OCAS was a valid instrument for evaluating medication adherence in Indonesian cancer patients taking oral chemotherapy. Therefore, it can be used for adherence monitoring in healthcare settings.
Achieving Hospital Efficiency through Inventory Management Strategies: A Systematic Review Sulistioningsih, Emi; Satibi, Satibi; Yuniarti, Endang
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.112087

Abstract

Background: In developing countries, pharmaceutical expenditures account for approximately 40–50% of total hospital costs. Therefore, effective management of medicines and pharmaceutical supplies is essential, as it significantly influences hospital operational efficiency and the quality of healthcare services.Objectives: This study aims to evaluate the impact of Economic Order Quantity (EOQ), Reorder Point (ROP), and Minimum-Maximum Stock Level (MMSL) inventory management methods on hospital efficiency.Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were applied to operate this systematic review. The articles published between 2009 and 2024 were identified through searches of Scopus, PubMed, Google Scholar, and the Garuda database. Studies that reported the application of EOQ, ROP, or MMSL methods in hospital pharmaceutical inventory management were included. A total of nine eligible studies were reviewed and synthesized to evaluate their impact on inventory efficiency indicators.Results: Nine studies met the inclusion criteria. Four studies applied EOQ and ROP methods, while five studies implemented the MMSL methods. The efficiency indicators evaluated inventory value, dead stock, stock out, inventory turnover ratio (ITOR), and customer service level. EOQ and ROP methods were associated with reductions in inventory value and stockouts, as well as improvements in ITOR and customer service levels. The MMSL generally reduced inventory value, stockout frequency, stockout value, and dead stock, either significantly or non-significantly, and increased ITOR. However, one study reported an increase in inventory value due to unstable supply conditions before implementation, and another reported a decrease in ITOR related to ordering policy constraints. Overall, the findings suggest that the EOQ, ROP, and MMSL methods generally improve inventory efficiency; however, several studies reported inconsistent or non-significant effects on certain indicators, such as the inventory turnover ratio and inventory value, under specific operational conditions.Conclusion: This systematic review indicates that the Minimum–Maximum Stock Level and Economic Order Quantity, Reorder Point methods are potentially beneficial strategies for enhancing inventory efficiency in hospital settings.

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