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Kota medan,
Sumatera utara
INDONESIA
Buletin Farmatera
ISSN : 2528410X     EISSN : 2528410X     DOI : -
Core Subject : Health,
Arjuna Subject : -
Articles 244 Documents
Cholesterol Levels After Maximum Physical Activity in White Rats (Rattus Norvegicus) Togatorop, Wilson H. S.; Harahap, Novita Sari
Buletin Farmatera Vol 6, No 1 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i1.4630

Abstract

The effect of physical activity on biological functions can be either positive or negative influences. Severe physical activity can increase oxygen consumption by 100-200 times compared to resting conditions. Increased use of oxygen, especially by muscle contracting, causes an increase in the number of free radicals. This study aims to determine the effect of maximum physical activity on cholesterol levels in white rats. The research design was used an experimental study with a post-test and control group design. Subjects were male white rats (Rattus Norvegicus), 20 of them were 3-4 months old, body weight was 180-200 grams. Subjects were divided into 2 groups randomly, each group consisted of 10 white rats, namely the control group: not given maximum physical activity; group treated: given maximum physical activity in the form of swimming until almost submerged. The results showed a significant increase in cholesterol levels (p=0.035; p0.05) in the treatment group, namely the group that was given maximum physical activity in the form of swimming to almost drowning, compared to the control group, namely the group that did not swim. The study concluded that there was an effect of maximum physical activity on blood cholesterol levels in white rats (Rattus Norvegicus).
Description of Ascariasis in Children Aged 2 to 12 Years at the Martha Friska Hospital, Pulo Brayan, Medan Said Munazar Rahmat
Buletin Farmatera Vol 5, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v5i3.4368

Abstract

Province of North Sumatera is one of the provinces with the most Ascariasis cases which affects children. This study aims to determine the description of ascariasis patients aged 2-12 years who are treated at the Martha Friska Pulo Brayan Hospital, Medan. This study is a descriptive study with a method cross-sectional, using consecutive sampling, which was conducted on patients who met the inclusion criteria from January to October 2017. The results of the study showed that most of the ascariasis subjects were male, pre-school age with good nutritional status, had normal Hb and Eosinophil levels.
Potentiality of Cannabis as an Antibiotic (Antimicrobial) Agent Rahadian, Wurgan
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.5632

Abstract

Cannabis sativa, or widely known as ganja and other names in Indonesia, is a plant that could not be used in the health care system in Indonesia. It is because cannabis is still a Class 1 Narcotic. However, trends within the last few years show that cannabis has medicinal properties, and is already approved as medicine and (even) for recreational means in several nations/countriesThailand is the first nation in Southeast Asia that did. This article aims to emphasize the antimicrobial potential that cannabis has. Since conventional antibiotic is considered unable to provide, it is important to find another source to counter the high rates of antibiotic (antimicrobial) resistance. Moreover, this article is also aimed to introduce one of the potentials that cannabis have to Indonesia since scientific article written in Bahasa is rare.
Bacteriology Test to Detect Coliform Bacteria in Beverages Sold at University Cafeteria in Medan Ade Pryta Romanauli Simaremare
Buletin Farmatera Vol 5, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v5i3.3437

Abstract

TThe World Health Organization standard for clean and safe water is that 95% of the water samples examined do not contain coliform organisms per 100 mL. Contaminated beverages will lead to digestive tract diseases. Food poisoning cases come from contaminated can be sourced from school canteens, street vendors factories, households, family parties, and even hotels. One of the most frequent and sensitive laboratory tests to detect microorganisms contamination in water is a bacteriological examination. This research aimed to determine the microbiological quality of beverages sold in the university canteens in Medan.The microbiological examination is carried out by the Most Probable Number (MPN) method that consists of two stages, presumptive and confirmation test. From 15 samples of beverages tested, the percentage of samples contaminated with coliform bacteria was 100%, based on WHO criteria were low-risk category by 1 sample (6.7%), intermediate-risk by 5 samples (33.3%), and high-risk category by 9 samples (60%). Therefore, beverages sold in the canteen did not meet the condition for appropriateness to be consumed because of contamination by coliform bacteria.
The Relationship between Changes in Nutrition Status and Length of Hospitalization in Patients in Department of Internal Medicine at University of Sumatera Utara Hospital Lubis, Nenni Dwi Aprianti; Sianturi, Chaca Theresia; Balatif, Ridwan
Buletin Farmatera Vol 6, No 1 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i1.4446

Abstract

The nutritional status of patients is one factor that influences the length of stay. This study is an analytic study with a cross-sectional design aiming to observe nutritional status, length of treatment, and the relationship between the two variables. The population in this study were patients aged 19-64 years who were treated in the Internal Medicine KSM at USU Hospital in the period August to October 2019. 52 patients were the study samples, with consecutive sampling as the sample selection technique used. We collected research data as nutritional status and length of stay through anthropometric measurements and structured interviews. We distinguish nutritional status based on Body Mass Index (BMI) and Subjective Global Assessment (SGA). The results showed 34 patients (65.4%) based on BMI values decreased nutritional status from 21.473.79 to 21.183.83 Kg /m2. Based on SGA, 32 patients (61.5%) experienced a decrease in score. The mean treatment period was 5.021.36 days. From the chi-square test results, it is known that changes in nutritional status based on BMI have a significant relationship to the length of stay with a p-value 0.05.
Micronutrient Supplementation Therapy in Subfertile Men: A Systematic Study Akbar, Aidil
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.8920

Abstract

In Indonesia, the infertility rate reaches 16% of couples of childbearing age, and 50% of cases are caused by male reproductive disorders. In the current study, micronutrient substitution therapy can increase sperm count and motility in subfertile men but has not shown consistent results. This study is a systematic study that aims to determine the effectiveness of micronutrient supplementation therapy for subfertile cases and what micronutrients are used for subfertile therapy. A literature search was carried out using the Google Scholar application with the keywords supplementation therapy in subfertile, from the results of a literature search using the prism method, 18 articles were found that included in the inclusion criteria, and it was found that almost all articles stated that micronutrition supplementation therapy in subfertile patients showed improved results. the number and motility of sperm cells and the micronutrients that are widely used are zinc, carnitine, Co-Q10, Vitamin E, Vitamin C, Selenium, Vitamin B12. It can be concluded that micronutrient supplementation can improve the number of live sperm cells and sperm motility.
ApaI Vitamin D Receptor Gene Polymorphisms in Psoriasis Oentari, Widyaningsih; Roesyanto-Mahadi, Irma D; Siregar, Yahwardiah
Buletin Farmatera Vol 6, No 1 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i1.6528

Abstract

Psoriasis is a chronic autoimmune skin disorder that is an autoimmune disease and still considers a global problem. This condition is suspected to be contributed by genetic and environmental factors. Several studies have shown an association between vitamin D gene receptor polymorphisms and the risk of psoriasis. This study was an observational study, which involved 64 research subjects, who were psoriasis patients. Each subject was interviewed and went through physical examination, also Polymerase Chain Reaction - Restriction Fragment Length Polymorphism (PCR-RFLP) examination to determine ApaI (rs7975232) vitamin D receptor gene polymorphism. After the tabulation of the data, we found that the age of psoriasis onset in this study was 21 to 40 years old with an average of 34.40 14.98 years old. The majority of our subjects ApaI VDR gene polymorphism genotype was aa (53.1%). This is consistent with the results of several studies conducted in Asia.
ApaI Vitamin D Receptor Gene Polymorphisms in Psoriasis Widyaningsih Oentari; Irma Damayanti Roesyanto-Mahadi; Yahwardiah Siregar
Buletin Farmatera Vol 5, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v5i3.3973

Abstract

Psoriasis is a chronic autoimmune skin disorder that is an autoimmune disease and still considers a global problem. This condition is suspected to be contributed by genetic and environmental factors. Several studies have shown an association between vitamin D gene receptor polymorphisms and the risk of psoriasis. This study was an observational study, which involved 64 research subjects, who were psoriasis patients. Each subject was interviewed and went through physical examination, also Polymerase Chain Reaction - Restriction Fragment Length Polymorphism (PCR-RFLP) examination to determine ApaI (rs7975232) vitamin D receptor gene polymorphism. After the tabulation of the data, we found that the age of psoriasis onset in this study was 21 to 40 years old with an average of 34.40 ± 14.98 years old. The majority of our subjects ApaI VDR gene polymorphism genotype was aa (53.1%). This is consistent with the results of several studies conducted in Asia.
HUBUNGAN KUALITAS TIDUR DAN KECEMASAN DENGAN KEJADIAN SLEEP PARALYSIS PADA MAHASISWA PENDIDIKAN DOKTER UNIVERSITAS SYIAH KUALA Suherman, Suherman; Razali, Rezania; Helmi, Denada Putri
Buletin Farmatera Vol 6, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i3.4333

Abstract

Sleep paralysis is a sleep disorder classified as a rapid-eye-movement (REM) sleep-related parasomnia which is characteristic of the inability to perform voluntary movements at sleep onset or on awakening. Medical students have a high academic burden that causes physical and mental problems such as poor sleep quality and anxiety that are risk factors for sleep paralysis. This research aims to determine the relationship between sleep quality and anxiety with the incidence of sleep paralysis among Medical Students of Universitas Syiah Kuala. These three variables were measured by Pittsburgh Sleep Quality Index (PSQI), State-Trait Anxiety Inventory-Trait (STAI-T), and modified Unusual Sleep Experience Questionnaire (USEQ) respectively. The type of research is an analytical observational study with a cross-sectional design. The sample is 216 respondents who are taken by proportional random sampling. The statistical analysis of the research was analyzed using the contingency lambda test and logistic regression test. The result of the research showed that 86.3% of respondents experienced poor sleep quality with sleep paralysis and 78,4% of respondents experienced anxiety with sleep paralysis. This study concludes that there is a significant relationship between sleep quality and anxiety with the incidence of sleep paralysis.
The Relationship between Sleep Quality and Hba1c Levels in Type 2 Diabetes mellitus Patients at Dr. Pirngadi Medan in 2019 Zalukhu, Nensi Aristya; Marpaung, Octo P; Gurning, Poida PB
Buletin Farmatera Vol 6, No 1 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i1.4625

Abstract

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