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Herb-Medicine Journal
Published by Universitas Muhammadiyah Purwokerto
ISSN : -     EISSN : 2620567X     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Herb-Medicine Journal (HMJ) merupakan Terbitan Berkala Ilmiah Herbal, Kedokteran, dan Kesehatan diterbitkan oleh Fakultas Kedokteran Universitas Muhammadiyah Purwokerto dengan frekuensi terbit 2 (dua) kali dalam setahun yaitu di bulan April dan Oktober. Jurnal ini merupakan media komunikasi ilmiah bagi siapapun yang tertarik menekuni bidang herbal baik dalam proses pendidikan, penelitian, maupun pengabdian kepada masyarakat yang dihubungkan dengan bidang kedokteran maupun kesehatan secara luas. Secara terbuka, redaksi menerima kontribusi artikel ilmiah tentang herbal, kedokteran, dan kesehatan dari pihak manapun yang ingin berpartisipasi dalam perkembangan dunia herbal, kedokteran, dan kesehatan.
Arjuna Subject : -
Articles 105 Documents
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Karakteristik Pasien Tumor Orbita Di PMN RS Mata Cicendo Bandung Periode 2017-2018 Ira Citra Ningrom; Andi Muh. Maulana; Susiyadi Susiyadi; Raudatul Janah
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 2 (2021): Herb-Medicine Journal April 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i2.10380

Abstract

Orbital tumors are tumors that occur in the orbital area where they can affect the outside of the orbit and the inside of the orbit. At present, it is still rare to report the prevalence of orbital tumors in the world. In developing countries such as Indonesia, reports on the incidence of orbital tumors are also rarely reported. Diagnosis and appropriate therapy if we recognize the characteristics of these orbital tumors. The purpose of this study was to determine the characteristics of orbital tumor patients at PMN Cicendo Eye Hospital Bandung. This research is a descriptive observational study with cross sectional method with total sampling technique. Data were collected retrospectively based on medical records in the form of age, sex, eyes involved, tumor location, surgery, clinical diagnosis, and histopathological results. The results showed that orbital tumors with the majority of age> 45 years (43.3%), male gender (55.4%), involvement of the left ocular eye (51.18%), with the most frequent location not in the conjunctiva, palpebral and retrobulbar (36.8%), clinical diagnosis of benign tumors (68.3%) were cysts (22.4%), the most histopathological results of benign tumor lesions (71.4%) were inflammation (17%). So it can be concluded that knowing the characteristics of this orbital tumor will have an impact on the therapy given will be appropriate.
Potensi Curcumin dan 4 Herbal Empon-Empon Dalam Memodulasi Kekebalan Sel T Terhadap Covid-19 Aryo Tedjo; Dimas Noor; Rudi Heryanto
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.10209

Abstract

Longer immunity to Severe Acute Respiratory Syndrome-CoronaVirus-2 (SARS-CoV-2) infection is thought to occur through memory cellular responses by activity of specific T lymphocytes. However, most patients with Coronavirus disease-19 (Covid-19) experienced a decrease in the number of T lymphocytes or lymphopenia. Agents that help maintain T cell counts such as Curcumin appear to have played an important role during the Covid-19 pandemic. Curcumin is known to provide a balance between T cell effectiveness and T cell autoaggressiveness, as well as restoring memory T cell function as observed in tumor-induced mice. The mixture of 4 herbal extracts of empon-empon which is commonly used as herbal medicine, namely temulawak, ginger, lemongrass, and turmeric, is thought to have the same effect as curcumin. This is known from the tracing of a plant-protein-compound database which shows that there are not many compounds other than curcumin that can modulate T cells. It is necessary to study the role of Curcumin and a mixture of 4 herbal empon-empon in modulating T cells in cases of infection by the SARS-Cov-2 antigen.
Etik Dan Profesionalisme Perawat Dan Bidan Puskesmas Marawola Kabupaten Sigi Pada Masa Tanggap Bencana Gempa Bumi Nasrun Nasrun; Fathya Fathya
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 2 (2021): Herb-Medicine Journal April 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i2.9445

Abstract

Palu city, Donggala, was hit by a 7.4 scale earthquake followed by a tsunami and liquefaction in September 2018. Numerous casualties were reported, particularly Maralowa health centre, Sigi district. Medical personnel should strictly adhere to their competencies. However, it is not uncommon to act beyond their capacity during a natural disaster. We are interested in investigating the ethical issues and professional aspect of medical personnel during an emergency. The research was conducted from March to June 2020, with qualitative methods using in-depth interviews of 8 participants who lived in Marawola Health Center at the time of the earthquake disaster. We used the Miles and Huberman method (1992) for data analysis. Medical personnel experienced a heavy load of working burden and psychological pressure; they were even unprepared for this condition. Overlapping competency is happening among medical personnel, but we did not found any ethical issues nor professionals breach during practice in Marawola Health Center
Manajemen Nyeri Non Farmakologi Post Operasi Dengan Terapi Spiritual “Doa dan Dzikir”: A Literature Review Tina Muzaenah; Ari Budiati Sri Hidayati
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.8022

Abstract

Manajemen nyeri sangat penting bagi pasien bedah untuk mencegah efek samping nyeri post operasi dan memfasilitasi pemulihan. Manajemen nyeri non farmakologi mengurangi efek emosional dari nyeri, meningkatkan penyesuaian dan membuat pasien percaya dapat mengendalikan rasa nyerinya, sehingga mengurangi nyeri dan meningkatkan tidur. Melakukan literature review terhadap artikel-artikel yang meneliti tentang menejemen nyeri non farmakologi pada pasien post operasi dengan terapi spiritual “doa dan dzikir”. Menggunakan database dengan penelusuran elektronik pada Google, Google Scholar dan PubMed yang dipublikasikan pada tahun 2013-2018. Lima artikel dipakai dalam review. Tiga artikel menyebutkan manajemen nyeri non farmakologi dengan membaca doa dan dzikir: melafalkan bacaan Tasbih 33 kali, Tahmid 33 kali, Takbir 33 kali, Tahlil 33 kali, Alhauqalah 33 kali selama 10-15 menit atau 30 menit. Diawali dengan melakukan tehnik napas dalam selama 5 menit atau membaca dzikir Hazrate Zahra (menyebut nama “Allah”) 100 kali. Dilanjutkan membaca surat Al-fatihah dan  diakhiri doa menghilangkan rasa sakit 7 kali. Dipraktikkan dengan posisi duduk/berbaring dengan nyaman, dengan mata tertutup. Dua artikel lain dengan mendengarkan doa "Ya man esmoho davaa va zekroho shafa, Allahomma salle ala mohammad va ale mohammad" selama 20 menit pada post operasi atau pembacaan doa salawat syifa ' dan dzikir pada intraoperasi. Doa dan dzikir adalah teknik non farmakologi berbiaya rendah, mudah, nyaman dilakukan kapanpun dan dimanapun, tidak memiliki efek samping. Membaca doa dan dzikir maupun mendengarkannya terbukti menurunkan intensitas nyeri post operasi 
Giant Condyloma Accuminata in Pregnancy, Use of Trichloroacetic Acid combined with electrocauterization and excision Procedure: A Case Report Putri Cinthya Ismihari; Riyana Noor Oktaviyanti
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.10252

Abstract

Condyloma acuminata is a sexually transmitted disease caused by the Human Papilloma Virus (HPV). During pregnancy, condyloma acuminata can proliferate rapidly due to changes in immunity and increased blood supply. One of the safest therapeutic modalities is trichloroacetic acid (TCA). Electrocautery is another modality in pregnant patients.  A 16-year-old woman, 6-months pregnant, complained of a wart-like lump in the pubic area getting more prominent since the last two weeks and covering the vagina surface. The lump is not itchy and painless. From history-taking it was found that patient often changes partners. On physical examination, the lesions were multiple papules with a verrucous surface. The results of the work-up showed a positive acetowhite test. Patients are then treated with a TCA of 80-90% during pregnancy and followed by electrocautery and excision during cesarean section. The results of 80-90% TCA treatment followed by electrocautery and excision were satisfactory, and there were no recurrences when the patient went for a follow-up. TCA is a substance that is caustic and can erode skin and mucous membranes. TCA works by coagulation of proteins which causes dryness of cells and tissues. TCA is safe for pregnant women. Combination of TCA 80-90% with electrocautery and excision, in this case, proved to be effective with no sign of recurrence. The combination of TCA therapy with electrocautery and excision has proven effective and safe for pregnant patients.
Hubungan Kecemasan, Depresi Dan Stres Dengan Kualitas Tidur Mahasiswa Fakultas Kedokteran Selama Pandemi Covid-19 Nida Faradisa Fauziyah; Khatifah Nur Aretha
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 2 (2021): Herb-Medicine Journal April 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i2.10064

Abstract

Coronavirus disease 2019 (COVID-19) is a sustainable health problem in 200 countries around the world. Public health emergency condition during pandemics such as SARS, MERS and Ebola are associated with increased psychological distress in the affected population. Negative impacts such as anxiety, depression and stress on students may become a burden on the mental and emotional health of students which in turn will affect the quality of student sleep. The author was interested in knowing about the relationship between anxiety, depression and stress with the quality of sleep of medical students during the COVID-19 pandemic. This study used an analytic observational study design with a cross sectional approach. This study was conducted in December with 81 students as respondents. This study used the DASS-42 questionnaire to measure anxiety, depression, stress and the PSQI to measure sleep quality. The results showed that 32.1%, 27.2%, 42% and 48.1% of students experienced anxiety, depression, stress and poor sleep quality. Statistical data measurement was done by using logistic regression, the results obtained p value = 0.030 (OR 3.967, 95% CI [1.143-13.722]), p = 0.004 (OR 11.456, 95% CI [2,217-59,196]), p = 0.043 (OR 0.314, 95 % CI [0.102-0.962]). From this study it can be concluded that anxiety, depression and stress had correlation with the sleep quality of students at the Faculty of Medicine, Muhammadiyah University of Surakarta during the COVID-19 pandemic.
Profil Penderita Stroke Berulang Rumah Sakit Muhammadiyah Malang Periode Juli-Agustus 2019 Risma Karlina Prabawati; Azizah Siena Pitaloka
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 3 (2021): Herb-Medicine Journal Juli 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i3.8147

Abstract

Stroke dapat mempengaruhi kehidupan penderita, baik berupa kecacatan maupun kematian. Stroke dibagi menjadi stroke iskemik dan perdarahan. Terjadinya stroke berulang dapat mempengaruhi status kognitif dan angka harapan hidup penderita. Penelitian ini bertujuan untuk mengetahui profil penderita stroke berulang di Poliklinik Saraf Rumah Sakit Muhammadiyah Malang pada bulan Juli-Agustus 2019. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross-sectional. Stroke berulang terjadi terbanyak pada laki-laki (54.26%), usia 56-65 tahun (41.5%), dan tingkat pendidikan perguruan tinggi (30%). Stroke berulang sering terjadi pada pasien dengan usia yang lebih tinggi, pendidikan tinggi, dan adanya riwayat hipertensi. Upaya promotif dan preventif berupa edukasi dan promosi kesehatan sebaiknya selalu dilakukan agar tidak terjadi stroke berulang yang beresiko memperburuk fungsi kognitif.
Pengaruh Buah Sirsak Terhadap Faktor Risiko Kardiovaskular (Kolesterol Total, HDL, LDL, Trigliserida) Haidar Alatas
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 2 (2021): Herb-Medicine Journal April 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i2.6805

Abstract

Soursop fruit contains phenolic, tannins, flavonoids. Phenolic inhibit xanthine oxidase inhibitors which inhibit the production of uric acid, this will affect in decreasing cardiovascular risk. Tannins reducing triglyceride levels. Flavonoids reduce HMG-CoA reductase and total cholesterol. Several studies conducted on animal experiments and the results of soursop fruit reduce lipid profile. What is the effect of soursop fruit consumption on cardiovascular risk in healthy humans? This epidemiological research was conducted in Mlati, Sleman, Indonesia. There were 143 subjects that conform to the inclusion and exclusion criteria subsequently randomized to two groups. Group I was given 2x100 g/day of soursop and group II was without soursop. A laboratory examination was conducted of total cholesterol, HDL, LDL, and triglyceride levels at weeks 0, 7, and 13 both in the soursop and non-soursop groups. Regular soursop consumption was evaluated every two weeks for three months. Data analysis was performed using an independent t test, a nonparametric Mann–Whitney test, and a chi-square test. There was no significant difference in total cholesterol (p=0.254 and p=0.932), HDL (p=0.400 and p=0.960), LDL (p=0.221 and p=0.710), triglycerides (p=0.423 and p=0.580) between the soursop and non-soursop groups. The consumption of soursop fruit at 2x100 g/day has no significant effect on improvement in cardiovascular risk (total cholesterol, HDL, LDL, triglycerides) in healthy subjects, but in subjects with hypercholesterolemia and hypertriglyceridemia, the mean cholesterol and triglyceride levels decreased at week 7 and 13 compared to no soursop consumption
Hubungan Antara Usia Ibu Hamil dengan Preeklampsia Tipe Lambat di Rumah Sakit PKU Muhammadiyah Surabaya Ali Mustofa; Ninuk Dwi Ariningtyas; Kartika Prahasanti; Muhammad Anas
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.9737

Abstract

Preeclampsia is one of the most common complications in pregnancy that can lead to various complications such assevere illness, long-term disability, andmaternal, fetal, and neonatal mortality. The prevalence of preeclampsia, 30%-40% can cause maternal mortality, and 30%-50% can lead to perinatal mortality. Maternal age is one of the riskfactors for late-onset preeclampsia. Maternal age is grouped into two categories; extreme age (<20 years and> 35 years)and reproductive age (21-35 years). This studyaims to determine the relationship between maternal age and late-onsetpreeclampsia at PKU Muhammadiyah Surabaya Hospital from January to June 2020. The research method used isobservational analytic with case control design. The samples involved were pregnant women visiting PKUMuhammadiyah Surabaya Hospital from January to June 2020. The data were analyzed using a statistical test ofcontingency coefficient correlation. The results showed that respondents who experienced late-onset preeclampsia inthe extreme age group (<20 years and> 35 years) were 37 respondents (100%) and in reproductive age (21-35 years)were 28 respondents (80%), the respondent who did not experience late-onset preeclampsia in extreme ages (<20 yearsand> 35 years) was 0 respondents(0%) and in reproductive age (21-35 years) were 7 respondents (20%). The resultsof the statistical test for the contingency coefficient correlation showed a p-value of 0.004 below (≤0.05). All thingsconsidered, there was a significant relationship between maternal age and late-onset preeclampsia at the PKUMuhammadiyah Surabaya Hospital from January to June 2020.
Pengaruh Pemberian Ekstrak Etanol Daun Kemangi (Ocimum basilicum L.) Terhadap Cedera Tubulus Ginjal Farah Akhwanis Syifa; Rizka Adi Nugraha Putra; Andi Muhammad Maulana; Susiyadi Susiyadi
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 4, No 4 (2021): Herb-Medicine Journal Oktober 2021
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v4i4.4555

Abstract

According to the European Food Safety Authority (EFSA),the allowed level of Monosodium glutamate (MSG)consumption is 30 mg / kgbw per day. Several studies show that long-term MSG is toxic to the kidneys bycausingoxidative stress and decreasing thekidney function.This study was based on the potential for impaired kidneyfunction and structure caused by excessive consumption of MSG and basil leaves (Ocimum basilicum L.) asantioxidant plants with flavonoid content. To find out the effect of basil (Ocimum basilicum L.) leaves’ ethanolextract dose 175 mg / kgbw, 350 mg / kgbw and 700 mg / kgbw against kidney tubular injury on white rats WistarStrain induced by MSG.This study was a quasi-experimental study with a randomized post-test only controlledgroup design. The number of samples was 25 ABM, divided into five groups, the positive control group (K+), thenegative control group (K-) and the treatment group (K1,K2 and K3).In the group given basil leaves ethanol extractdoses of 175, 350 and 700 mg / kgbw, there was a decrease in tubular injury in the kidney of the white rat (Rattusnorvegicus) Wistar strain induced by MSG 1.6 g/day orally. The optimal dose in this study was 700 mg / kgbw. Teststatistics indicated significant differences in all five groups (p < 0.05).The administration of ethanol extract of basilleaves (Ocimum basilicumL.) was able to prevent tubular injury in the kidney of the white rat (Rattus norvegicus)Wistar strain induced by MSG. Kadar konsumsi MSG yang diperbolehkan menurut Europian Food Safety Authority (EFSA) yaitu 30 mg/kgBB per hari. Beberapa studi pada hewan coba menunjukkan bahwa pemberian MSG jangka panjang bersifat toksik padaginjal dengan menyebabkan stress oksidatif dan menurunkan fungsi ginjal. Penggunaan tanaman yang mengandungantioksidan dapat meningkatkan mekanisme dalam tubuh untuk mencegah stres oksidatif. Penelitian ini didasarkanoleh potensi terjadinya gangguan fungsi dan struktur ginjal akibat stres oksidatif yang disebabkan oleh konsumsiMSG berlebih serta daun kemangi (Ocimum basilicum L.) sebagai tanaman antioksidan dengan kandunganflavonoid.Mengetahui pengaruh pemberian ekstrak etanol daun kemangi (Ocimum basilicum L.) dosis 175,350 dan700 mg/kgBB terhadap cedera tubulus pada BBT ginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksiMSG.Penelitian ini merupakan jenis penelitian quasi-experimental dengan rancangan randomized post test onlycontrolled group. Jumlah sampel sebanyak 25 BBT, terbagi menjadi lima kelompok, yaitu kontrol positif (K+),kontrol negatif (K-) dan kelompok perlakuan ekstrak daun kemangi (K1, K2 dan K3).Pada kelompok pemberianekstrak etanol daun kemangi terjadi penurunan cedera tubulus pada ginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksi MSG 1,6 g/hari secara oral.  Dosis optimal ekstrak etanol daun kemangi padapenelitian iniyaitu 700 mg/kgBB. Uji statistik menuunjukkan perbedaan yang signifikan pada kelima kelompok (p<0,05). Pemberian ekstrak etanol daun kemangi (Ocimum basilicum L.) dapat mencegah terjadinya cedera tubulus padaginjal tikus putih (Rattus norvegicus) galur Wistar  yang diinduksi MSG.

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