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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 273 Documents
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Effect of Ethanol Extract of Suruhan Leaves (Peperomia Pellucida L. Kunth) on Blood Sugar Levels and Macroscopic Wounds in Male White Rats of the Wistar Strain (Rattus norvegicus) Diabetic Ulcer Model Hakim, Enggrek Pelita; Siahaan, Jekson Martiar; Anto, Endy Juli; Eyanoer, Putri Chairani
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.733

Abstract

Background: High blood sugar levels can cause diabetes mellitus (DM), which currently means more than one in 10 adults live with diabetes, with the biggest risk factor being obesity. Wound healing in DM patients will be hampered and increase the incidence of diabetic ulcers in Indonesia by 12% and the risk of developing diabetic ulcers by 55.4%. Diabetic ulcers and gangrene cases in Indonesia are the most common cases found in hospitals. Mortality due to ulcers and gangrene ranges from 17-23%, while the amputation rate ranges from 15-30%. Therapeutic potential in the treatment of diabetic ulcers is possessed by suruhan leaves which have anti-inflammatory, antipyretic, antimicrobial and anticancer effects, as well as having analgesic effects. Subjects and Method: A total of 30 male white rats of the Wistar strain (Rattus norvegicus) were divided equally into control groups, negative control (STZ induction 40mg/kgBW), positive control (STZ induction 40mg/kgBW with metformin 50mg/kgBW/day), treatment group I (STZ induction 40mg/kgBW with ethanol extract of shrike leaves 40mg/kgBW), and treatment group II (STZ induction 40mg/kgBW). kgBB with ethanol extract of 80 mg/kgBB leaves). Next, blood sugar levels (KGD) and macroscopic examination of diabetic ulcer wounds are carried out. Data were analyzed using the Anova test. Results: The lowest blood sugar levels (183.83 ± 11.39), the lowest wound area (6.89 ± 0.86), and the highest percentage of excision wound healing (89.67 ± 1.37) were found in the positive control group. There was a significant relationship between groups of mean blood sugar levels, between groups of wound area, and between groups of healing percentage of excision area (P<0.05). Conclusion: Administration of ethanol extract of suruhan leaves (Peperomia pellucida L. Kunth) had an effect on reducing blood glucose levels and healing diabetic ulcer wounds in STZ-induced diabetic ulcer model mice.
The Impact of Inducing Compelled Body Weight Shifts in Improving Dynamic Balance on Non-Hemorrhagic Stroke Patients Anugrah, Welya Nesvi; Sudaryanto, Wahyu Tri
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.734

Abstract

Background: Stroke is a brain attack that occurs suddenly where there is partial or complete disruption of brain function as a result of disruption of blood flow due to blockage or rupture of certain blood vessels in the brain, causing brain cells to lack blood, oxygen or nutrients and ultimately can cause These cells die in a relatively short time. In general, strokes are divided into 2, namely hemorrhagic and non-hemorrhagic strokes. Balance disorders due to loss or decreased motor function make stroke patients vulnerable to falls. The aim of this research is to determine the effect of giving Compelled body weight shift on non-hemorrhagic stroke to improve dynamic balance. Subjects and Method: This research was a quasi experiment conducted in Sri Meranti Village, Rumbai, Pekanbaru, Indonesia, from June 2023. 12 non-hemorrhagic stroke patients were selected using purposive sampling. The dependent variable was dynamic balance. The independent variable was compelled body weight shift. Body dynamic balance was measured using Berg balance scale. Body dynamic balance before and after intervention was examined using . Results: There was a significant increase in balance between the control group and the experi­men­tal group in non-hemorrhagic stroke sufferers after the compelled body weight shift was carried out (p<0.001). Conclusion: Compelled body weight shift balance training can be used to improve the body dynamic balance in non-hemorrhagic stroke patients.
Relationship between Pregnancy and Lactation Status and De Quervain's Syndrome Naim, Karimatun; Wahyuni
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.735

Abstract

Background: De Quervain's Syndrome is a collection of symptoms accompanied by inflamma­tion and pain in the tendon sheath that covers the extensor pollicis brevis and abductor pollicis longus muscles. These symptoms appear as a result of cumulative (repeated) microtrauma and overuse causing malfunction of the tendon sheath. Cause of De Quervain's Syndrome is still not known for certain. Due to hormonal factors, it is more common in pregnant women and most common in people aged 30 to 55 years. This study aimed to examine the relationship between pregnancy and lactation on the incidence of de Quervain' syndrome. Subjects and Method: This was an observational study conducted at the PDHI Islamic Hospital, Yogyakarta, from August to September 2023. Total sample of 70 third trimester of pregnant women or lactating mothers who had children aged 1 month to 1 year was selected purposively. The dependent variable was De Quervain's syndrome. The independen variable was pregnancy and lactation. The data were collected using a questionnaire and analyzed by Chi square test. Results: Pregnancy and lactation reduced the risk of de Quervain's syndrome (OR= 0.34; 95% CI= 0.125 to 0.907; p=0.029). Conclusion: Pregnancy and lactation reduced the risk of de Quervain's syndrome.  
Effect of Exercise on Cognitive Ability, Cardiovascular Fitness, and Quality of Life in Post-Stroke Patients: Systematic Review and Meta-Analysis Maingu, Bertha Sylvester; Murti, Bhisma; Widyaningsih, Vitri
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.737

Abstract

Background: Following a stroke, cognitive ability, and cardiovascular fitness decline, exerting a substantial influence on physical rehabilitation and overall quality of life. Stroke management encompasses a multidisciplinary approach, with emerging studies highlighting the role of exercise in enhancing cognitive ability and cardiovascular fitness post-stroke. This study aims to analyze the effects of exercise on cognitive ability, cardiovascular fitness, and quality of life in stroke survivors, shedding light on potential therapeutic benefits. Subject and Methods: The PICO Model eligibility criteria were employed to execute the article search including P= post-stroke patients; I= exercises C= standard care, O= cognitive ability OR cardiovascular fitness OR quality of life. The study extracted articles from PubMed and Science­Direct databases, with keywords "exercises" AND "cognitive ability" OR "cardiovascular fitness" OR "quality of life" AND "post-stroke patients". Inclusion criteria required full-text articles with rando­mized controlled trial (RCT) designs, focusing on post-stroke patients and evaluating improve­ments in cognitive ability, cardiovascular fitness, or quality of life. PRISMA diagram and Review Manager 5.4.1 tool were used to analyse the selected articles. Results: 25 studies included in the review had 2,110 participants, across Asia; Australia, Europe, North America, and South America eligible for meta-analysis. The result indicated a positive effect of exercise on cognitive ability (SMD=0.68, CI 95% (0.21 to 1.16); p=0.005); cardiovascular fitness (SMD=0.63, CI 95% (0.17 to 1.08); p=0.007) and quality of life (SMD=0.60, CI 95% (-0.08 to 1.27); p=0.080). Conclusion: Engagement in diverse forms and durations of exercise emerges as a crucial element in post-stroke rehabilitation. This intervention signifies a promising avenue toward enhancing cognitive abilities, and cardiovascular fitness, and potentially elevating quality of life among stroke survivors.
The Role of Hypertonic Saline in Managing Malignant Cerebral Edema Due to Large Vessel Occlusion Stroke: A Case Report Zairinal, Ramdinal Aviesena; Malutfi, Chandrika Najwa; Hidayati, Diah Balqis Ikfi
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.738

Abstract

Background: Malignant cerebral edema (MCE) is a complication of large vessel occlusion stroke mainly treated by decompressive craniectomy. The aim of this case report is to demonstrate the efficacy of providing hypertonic saline (3% NaCl) as an alternative treatment for reducing intracranial pressure (ICP) in an MCE patient who refuses surgery. Case Presentation: A 66-year-old man went to the emergency department with unconsciousness, right-sided hemiplegia, and global aphasia for 4.5 hours before admission. His National Institutes of Health Stroke Scale (NIHSS) score was 12. The patient’s brain magnetic resonance imaging (MRI) revealed a large infarction on the left frontotemporoparietal lobe which caused a subfalcine herniation 1.4cm to the right side. He also suffered hyponatremia (115mmol/L). The family refused decompressive craniectomy. The patient received 200ml of 3% NaCl drip intravenous as an initial dose over 20 minutes every 6 hours. Subsequent administration is gradually reduced every 25ml with a distance adjusted to the patient’s condition up to 50ml as the last dose. The patient’s 90-day modified Rankin Scale (mRS) score was 4. Results: The patient with MCE in this case who was administered 3% NaCl as conservative therapy had satisfactory outcomes, as demonstrated by the improvement of the clinical neurological condition. Conclusion: In patients who decline surgery, 3% NaCl might be given as a conservative treatment option to reduce ICP while maintaining serum sodium levels under control. This case revealed a positive clinical result without complications.
Effect of Nerve Mobilization in Reducing Pain in Patients with Guyon Canal Syndrome Maliesgasari, Dita; Sudaryanto, Wahyu Tri
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.742

Abstract

Background: Guyon Canal Syndrome is a peripheral ulnar neuropathy caused by lesions of the distal ulnar nerve, specifically in the Guyon's tunnel which is at the base of the hypothenar eminence where the ulnar nerve branches and is susceptible to compression. These tunnel structures are frequently subject to cycling-related injuries, sudden compression or repetitive vibration. Guyon Canal Syndrome causes loss of motor, sensory function, or a combination of motor and sensory function. The aim of this research is to determine the effect of nerve mobilization on reducing pain in Guyon Canal Syndrome. Subjects and Method: This research is a quasi-experimental research conducted at the Grhasia Mental Hospital, Yogyakarta Special Region, in June-July 2023. A total sample of 8 patients diagnosed with Guyon canal syndrome was selected using purposive sampling. The sample was divided into 2 groups (1) 4 people received nerve mobilization and (2) 4 people received standard care. The dependent variable is pain. The independent variable is nerve mobilization. Pain was measured using the Quadruple Visual Analogue Scale (QVAS). The difference in pain scores before and after intervention in the two groups was tested using an independent t test. Results: The average difference in pain score reduction in the intervention group (Mean= -11.75; SD= 5.68) was greater than the control (Mean= -3.5; SD= 11.39), but not statistically significant (p= 0.242). Conclusion: The average difference in pain score reduction in the intervention group was greater than the control, but not statistically significant. Keywords: Guyon canal syndrome, pain, nerve mobilization
Nurse’s Characteristics and Their Understanding Regarding the Compatibility of Mixing Intravenous Drug Preparations in Hospital Settings Rizky Wiharti, Irda; Karuniawati, Hidayah
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.744

Abstract

Background: Drug incompatibility can occur in patients in hospital who receive one or more drugs at the same time due to incompatible drug mixing, and the mixture is said to be incompatible if there are precipitates, crystals, visual color changes. This research aims to determine the relationship between nurses' knowledge of incompatibility in mixing intravenous drug preparations, so that collaboration between nurses and pharmacists can occur in administering intravenous drugs and can reduce the occurrence of medication errors, especially when administering intravenous drugs. Subjects and Method: Cross sectional research was conducted in RSUD dr. Soeselo, Tegal, Central Java, November 2023. The research subjects were 152 nurses selected using purposive sampling technique. The dependent variable is knowledge. The independent variables are age, gender, length of work, duration of work, and training. Data was collected using a questionnaire and analyzed using multiple linear regression. Results: The number of survey respondents in this study was 152 people, with the majority being 73.7% female and 26.3% male. The average value of the nurses' age was 31.82 ± SD 5.09 and 6.14 ± SD 3.26 for the length of work of the nurses who took part in this study, and the average duration of work was 10.08 ± 2.00. In the multivariate analysis test, gender, last education, duration of work, length of work, age on knowledge had a p value of >0.005 so there was no significant effect. Conclusion: The majority of nurses still have a poor level of knowledge <75% on several questionnaire items. Apart from that, this research shows that there are still many nurses who do not understand intravenous stability and the stages of intravenous administration, which is shown in the question scores. So the role of clinical pharmacy in monitoring and providing education regarding nurse training regarding drug incompatibility is needed.  
The Effect of a Combination of Ultrasound and Stretching on the Pain Scores of Piriformis Syndrome Patients at the Padas Health Center, Ngawi Regency Imani, Kelvin Teguh; Fariz, Achmad; Hamidah, Nurul
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.746

Abstract

Background: Piriformis Syndrome is a pain in the pelvic area caused by prolonged or excessive contraction of the piriformis muscle so that the sciatic nerve is compressed or compressed. The physiotherapy treatment used is a combination of ultrasound and stretching. This study aimed to determine the effect of a combination of ultrasound and stretching in reducing pain in piriformis syndrome patients. Subjects and Method: The design of this study was a one-group pre-experimental and post-test design with 20 respondents who met the inclusion and exclusion criteria using a purposive sampling technique carried out in September-October 2023. Respondents had their pain scale measured using VAS (Visual Analog Scale) before and after physiotherapy treatment, namely; giving a combination of ultrasound and stretching 2 times a week for 4 weeks. Results: This study used the paired sample test hypothesis test with the median VAS value; (1) pre by 5.70; (2) posts by 3.35 and (3) P value by 0.00. Conclusion: It can be concluded that the combination of ultrasound and stretching is effective in reducing pain in cases of piriformis syndrome.
Surgical Precision in Lumbar Spinal Canal Stenosis: Optimizing Outcomes in a Young Adult with Suspected Infection through Decompression-Stabilization-Fusion Putra, I Gusti Ngurah Paramartha Wijaya; Febyan; Ustriyana, Nyoman Gede Grenata Nanda
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.747

Abstract

Background: This case report examines the uncommon occurrence of Lumbar Spinal Canal Stenosis (LSCS) in a 23-year-old male patient, highlighting the diagnostic challenges and unique aspects of managing this condition in young adults. Typically associated with aging and degenerative changes, LSCS poses a diagnostic dilemma when encountered in a young individual with nonspecific causation. Case Presentation: The patient reported persistent lower back pain since February 2023, primarily on the right side, escalating over the past three months. The pain intensified during prolonged sitting, standing, and walking, alleviated by lying down and analgesics. Radiating pain to both buttocks and legs, particularly on the right side, accompanied a four-month history of persistent right foot numbness. Referred from RS Siloam Kupang to RSAD Denpasar and subsequently to RSUP Prof IGNG Ngoerah, the patient received a diagnosis of Lumbar Spinal Canal Stenosis at L2-L3-L4, L5-S1, with suspected Spondylitis TB. Results: This case underscores the intricacies of diagnosing Lumbar Spinal Canal Stenosis in young adults, emphasizing the exploration of non-traditional causes. The patient underwent Debridement-Decompression-Stabilization-Fusion-Biopsy+Culture, experiencing postoperative improvement. Cultures showed no growth, and biopsy results were nonspecific. The final diagnosis was Lumbar Spinal Canal Stenosis at L2-L3-L4, L5-S1 due to Spondylitis TB dd/Pyogenic Infection, with bilateral Neural Foraminal Stenosis Grade III at L5. The discussion focuses on the rarity of this presentation in young individuals, challenges in diagnosis, and the efficacy of decompression-stabilization-fusion treatment for achieving positive outcomes in young adult patients. Conclusion: The case discussion emphasizes the complexity of managing Lumbar Spinal Canal Stenosis in a young adult, particularly when infection is suspected. The decision to pursue Decompression-Stabilization-Fusion was rooted in the patient's age, the need for structural stability, and the suspicion of infection.
Unveiling Atopic Dermatitis: Exploring Smoking, Obesity, and Fast Food as Pivotal Risk Factors - A Systematic Review Hibatullah, Faiz Nur; Kalada, Elisabeth Chelsea Uma; Baita, Etina Noor; Putra, Fabianus Yvan Marino Cahaya; Adiwinoto, Ronald Pratama; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.750

Abstract

Background: Atopic dermatitis (AD), also known as Eczema, is an inflammatory skin disease that causes dry, itchy skin. several risk factors for AD have been reported including demographics, socioeconomics, active and passive smoking, urbanization, diet, breastfeeding and timing of introduction of solid foods, obesity, physical exercise, fast food, and environmental air pollution. This study aims to better understand the effect of smoking, obesity, and fast food consumption as one of the risk factors of AD. Subjects and Method: Systematic review with the help of PICOs to search for eligible articles. Articles were searched from 3 different databases (PubMed, ScienceDirect, and Google Scholar) with the help of a search engine application, Publish or Perish (PoP), using the following keyword: “smoking AND atopic dermatitis”, “fast food AND atopic dermatitis”, “obesity AND atopic dermatitis”. Results: 10 articles matched the specified inclusion and exclusion criteria for this study. Whether or not smoking causes AD is still conflicting, few studies reported there is no correlation between smoking and AD, whereas other studies said otherwise. In contrast to that, second-hand smoke was found to be affecting AD conditions more (up to 2.320). Most of our eligible articles reported that obesity did cause severe reactions of AD up to 1.62 times. Frequent fast food consumption was also found to be causing severe AD conditions (OR=1.580). Conclusion: Obesity and fast food consumption are one of the causes of AD development and AD severity. The risk factor of cigarette smoking still conflicts with whether or not it affects AD conditions.

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