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INDONESIA
Indonesian Journal of Medicine
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
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Articles 273 Documents
Evaluating Compliance with Traditional Herbal Treatments in Type 2 Diabetes Mellitus Patients Mufidah, Naili Zahrotun; Murti, Bhisma; Tamtomo, Didik Gunawan
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.783

Abstract

Background: The management of diabetes mellitus is often faced with the challenge of adherence to antidiabetic herbs. Poor adherence to diabetes medication increases the risk of complications and death. This study aims to analyze the determinants related to treatment adherence in Type 2 DM patients. Subject and Method: The cross-sectional study was carried out at UPF Yankestrad Dr. Sardjito Tawangmangu Hospital. A total of 201 adult patients with Type 2 DM were selected in this study. The dependent variable is treatment adherence in Type 2 DM patients. The independent variables were education, knowledge, access to health services, family support, income, and side effects of treatment. Data was collected using questionnaires. Data were analyzed by double linearregression. Result: There was a statistically significant positive association between knowledge and medication adherence (b = 0.19; 95% CI = 0.12 to 0.26; p<0.001); access to healthcare (b = 0.37; 95% CI = 0.26 to 0.47 p<0.001); family support (b = 0.29; 95% CI = 0.20 to 0.39; p<0.001); income (b = 0.15; 95% CI = 0.01 to 0.29; p= 0.030); and there was a negative and statistically significant association between adverse events and medication adherence (b = -0.33; 95% CI = -0.49 up to -0.18; p<0.001). The model fit between the independent variables included in the linear multiple regression analysis model together was able to explain the variation in treatment adherence by 67.12% (Adj R-squared= 67.12%). Conclusion: Treatment adherence in Type 2 DM patients is positively related to knowledge, access to services, family support, and income. The independent variables included in the linear multiple regression analysis model together were able to explain the variation of treatment adherence by 67.12% (Adj R-squared = 67.12%).
Correlation between Troponin I and Serum Sodium and Potassium Levels in Acute Coronary Syndrome Rahma, Hadiyatur; Loesnihari, Ricke; Siregar, Dewi Indah Sari
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.794

Abstract

Background: Acute Coronary Syndrome covers a spectrum of conditions that include patients who have recently changed symptoms or clinical signs, with or without changes in the 12-lead electro­cardiogram, and with or without acute elevations in cardiac troponin (Tn) concentrations. Advances in technology have refined troponin testing and increased its accuracy in detecting and measuring cardiomyocyte injury, high sensitivity, and can detect small myocardial necrosis that is not detected on an electrocardiogram or CKMB examination. This study aims to analyze the correlation between troponin I and sodium and potassium levels in acute coronary syndrome. Subjects and Method: This study was an analytical observational research with a cross-sectional design, involving 40 patients with acute coronary syndrome who visited the Integrated Heart Center Emergency Department. The independent variable is acute coronary syndrome, while the dependent variables are troponin I, sodium, and potassium. The study was conducted at H.Adam Malik Hospital in Medan from February to March 2024. Patients were interviewed for medical history, and then blood samples were taken for troponin I examination and serum electrolyte (sodium and potassium) examination. Data were analyzed using the Spearman correlation test. Results: 40 study subjects, most of the study subjects over 55 years, mostly male (72.5%), with a smoking history of 67.5%, and a family history of hypertension of 52.5%. The median troponin I level was 6.09 ng/ml (range 0.12-15), the median sodium level was 143.5 mmol/L (range 130-155), and the mean potassium level was 4.19 mmol/L (SD= 0.52). There was a weak and non-significant positive correla­tion between troponin I and sodium (r= 0.129, p= 0.429), as well as a weak and non-significant positive correlation between troponin I and potassium (r= 0.059, p= 0.717). Conclusion: There was no correlation between troponin I and sodium, as well as troponin I and potassium.
The Effect of Turmeric-based Vaginal Liquid Soap with Different Concentrations on the Incidence of Vaginal Discharge and PH : Experimental Test on Santriwati of Darussholah II Islamic Boarding School North Pontianak Lutfiawaliah, Delvia; Fatmasari, Diyah; Arwani
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.795

Abstract

Background: As many as 90% of Indonesian women have the potential to experience vaginal discharge because of Indonesia's tropical climate. Hot and humid weather causes mold to easily develop and cause vaginal discharge in women. For this reason, there needs to be an innovation that can be used as one of the efforts to overcome vaginal discharge in general. The purpose of this study is to prove the potential of turmeric-based vaginal soap that is able to overcome vaginal discharge. Subjects and Method: This was a quasi experiment study. The study was conducted at the Darussholah II Islamic Boarding School, North Pontianak, Indonesia from November to December 2023. The sample was divided into 3 groups: (1) , namely groups 1, 2 and 3 with 5%, 10%, and 15% turmeric liquid soap interventions. The dependent variables studied were vaginal discharge and vaginal ph, and the independent variable was Vaginal Turmeric Soap. The analysis technique uses Wilcoxon bivariate analysis. Results: The average value of 5% soap whiteness reduction was 0.96+0.20, 10% was 0.88+0.33 and 15% was 0.92+0.27 with a p value of 0.585. The average value of the pH reduction of 5% soap was 0.60 + 0.57, 10% soap was 0.52 + 0.65, and 15% soap was 0.48 + 0.65 with a p value of 0.904. At a dose of 5%, the reduction in vaginal discharge and pH was the highest compared to other groups. And the results of the analysis showed that the administration of 5%, 10%, and 15% doses did not have a significant difference in changes in vaginal discharge and pH. Conclusion: A 5% dose of turmeric-based vaginal soap was more effective at treating vaginal discharge and lowering vaginal pH, compared to other groups in this study. It is hoped that young women will be more selective in choosing soap in maintaining pH and vaginal discharge, especially if used for a long period of time.
The Effect of Using a Dynamic Wrist Splint on Wrist Pain in Stroke Patients Rachmat, Nur; Kuncoro, Bambang; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.796

Abstract

Background: Hand movement function in hemiplegic stroke patients is impaired due to contractures and spasticity. Pain in the wrist joint often occurs when moved. This research aims to determine how dynamic wrist splints can reduce wrist pain in stroke patients. Subjects and Method: This was a quasi-expe­rimental study. The subjects were 20 hemiplegic stroke patients in Colomadu Karanganyar. The research was carried out in July – September 2023. The dependent variable was wrist pain. The independent variable was the use of a dynamic wrist splint. measurement the degree of pain using the Visual Analog Scale which is used to determine the level of pain felt by the sufferer. Data normality test using Shapiro-Wilk. The statistical test used in this research is wilxocon. Results: The ages of subjects ranged from 30 to 62 years. Wrist pain was reduced after the use of a dynamic wrist splint compared to levels before its use. Conclusion: There is an influence of dynamic wrist splints on wrist pain in stroke patients.
Clinical Outcomes Comparison in Administration of Secretome vs Hyaluronic Acid in Patients with Knee Osteoarthritis Kellgren-Lawrence Grade I-III Aryana, I Gusti Ngurah Wien; Suyasa, I Ketut; Dharmayuda, Cokorda Gde Oka; Febyan; Gunawan, Dary
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.798

Abstract

Background: The prevalence of OA in Indonesia is predicted to reach more than 20% of the population aged over 60 years in 2050, with a high risk of disability. So far, early treatment of osteoarthritis in the form of administering hyaluronic acid has not been completely satisfactory and tends to be progressive until ending in more invasive operative therapy. This study aimed to compare the clinical outcomes between secretome injection and hyaluronic acid in patients with Kellgren-Lawrence grade I-III knee osteoarthritis. Subjects and Method: This was a single-blind experimental study. This study was conducted in the orthopedic polyclinic at General Hospital Prof. Dr. I.G.N.G. Ngoerah Bali. A total sample of 36 knee osteoarthritis patients was selected using permuted block sampling with randomization. The sample was divided into two groups, (1) secretome (intervention group) and (2) hyaluronic acid (control group). The independent variables were secretome injection and hyaluronic acid injection. The dependent variable was pain. Pain was measured using Western Ontario and McMaster University (WOMAC), Knee Osteoarthritis Outcome Score (KOOS), Visual Analog Score (VAS), and Patient-Reported Outcome Measure (PROM). Results: Based on gender, there are more women than men and the right foot is more affected at 58.3%. Functional score parameters in each secretome and hyluronic acid group were compared between the 3rd and 6th months of follow-up. Pain in the hyaluronic acid group was lower than in the secretome group. Conclusion: Hyaluronic acid has better effect in pain reduction than secretome. Further studies could explore the underlying mechanisms and potential long-term effects to better understand these differences in pain outcomes.
Effect of Moringa Leaf Infusion (Moringa oleifera) on Reducing Blood Glucose and Total Cholesterol Levels in Mice (Mus musculus) with Diabetic Ulcers Napitupulu, Helen Debora; Siahaan, Jekson Martiar; Simangunsong, Batara
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.799

Abstract

Background: Diabetes mellitus is a chronic disease in the form of metabolic disorders, which is characterized by blood glucose levels (KGD) that exceed normal limits and are accompanied by impaired metabolism of carbohydrates, lipids, and proteins, as a result of abnormalities in insulin secretion. Diabetics are known to have slow wound healing. Moringa oleifera leaves or moringa plants contain flavonoid compounds, which can decrease glucose absorption. This study aims to determine the effect of moringa leaf infusion on blood sugar levels, glucose tolerance, cholesterol levels, body weight, and wound healing speed in mouse model animals. Subject and Method: This study is experimental using a posttest only controlled group design, using 25 male mice (Mus musculus) divided into 5 groups. The study was conducted at the Phytochemistry and Animal House Laboratory, Faculty of Medicine, Methodist University Indonesia from March to May 2022. The bound variables were body weight measured using a scale, current blood glucose levels and blood glucose levels with glucose loading measured with strips and glucometers, total cholesterol levels measured using strips and cholesterol measuring devices, and the length of mice wounds measured using a ruler. The free variable is the variation in the dose of moringa leaf infusion. The data were analyzed using the Anova and Kruskal-Wallis tests. Results: The administration of moringa leaf infusion had a significant effect on the reduction of the levels of each variable, namely a dose of 10% in body weight, a dose of 30% in KGD, 20% in KGD with glucose loading, 20% in cholesterol, and 20% in wound closure, which was proven based on the results of statistical tests. Conclusion: Moringa leaf infusion can lower blood sugar levels, blood sugar levels by glucose depletion, cholesterol levels, body weight, and accelerate wound healing in sucrose-induced mice, high fat diet, and PTU.
Decline in Estrogen Levels and Its Impact on Muscle Strength in Elderly Women: A Systematic Review Cahyaningrum, Hapsari; Silanurrahmi, Athaya Zuhra; Hakim , Gamadhan Kholid Rahman
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.755

Abstract

Background: In the musculoskeletal system, old age is closely related to a decline in muscle strength. Decreased muscle strength in women is caused by the influence of changes in estrogen hormone levels. Several studies were conducted to see how estrogen affects muscle mass, muscle function, muscle damage, muscle regeneration, inflammation in the body, mitochondrial funct¬ion, and substrate metabolism. Therefore, the study was carried out with the aim of conducting further study focusing on estrogen on muscle strength in elderly women.Subjects and Method: The study was conducted with a systematic review design. The study was carried out in accordance using PRISM guidelines with the PICO formula. Population: elderly women, Intervention: estrogen hormone, Outcome: muscle weakness. Article searches were carried out through several databases, namely PubMed, Cochrane Library, Scopus Database, and Physio-therapy Evidence Database (PEDro) with the keywords: estrogen OR "estrogen hormone" OR "muscle strength" OR "risk of falls" OR "menopause" OR "women elderly." Risk of bias assessment was carried out according to the study design of each article.Results: There were 10 articles involved in this study. The article has a cross-sectional and longitudinal study design. Articles had a low and medium risk of bias assessment. 6 articles stated that there was a relationship between changes in estrogen hormone levels and muscle weakness. 4 articles stated that there was no relationship between changes in estrogen hormone levels and muscle weakness. Conclusion: There is a inconsistent relationship between estrogen levels and muscle strength in elderly women.
Comparison of the Effects of Zig-Zag Run and Shuttle Run Exercises on Agility in Futsal Players Fahri, Ana Mustafiyah; Oktaviani, Vernanda; Asyhari, Atge Oktoreza
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.828

Abstract

Background: Futsal players really need agility so that they can improve their performance and get maximum results as well as improve the body's physiological systems and functions. Physiotherapy plays a role in efforts to improve player achievement by optimizing physical capacity and functional abilities so that maximum achievement is achieved. Agility exercises that can be used to improve agility are obstacle runs, zig-zag runs, and shuttle runs. The purpose of this study is to find out which has a greater effect between the addition of zig-zag run and shuttle run exercises on the agility of futsal players.Subjects and method: This was an experimental study to compare the effect of zig-zag run and shuttle run on agility. 30 futsal players aged 18-23 years were divided into two groups, i.e. zig-zag run and shuttle run, randomly. The dependent variable was agility. The independent variables were zig-zag run and shuttle run. Difference of agility score before and after intervention between groups was tested using independent t-test.Results: There was no difference of agility level between zig-zag run (Mean= 10.06; SD= 0.49) and shuttle run (Mean= 10.02; SD= 0.74) groups before intervention, p= 0.315. After intervention, there was a slight difference of agility level between zig-zag run (Mean= 9.77; SD= 0.43) and shuttle run (Mean= 9.73; SD= 0.74) groups, and it was marginally significant (p= 0.052). Conclusion: After intervention, there is a slight difference of agility level between zig-zag run and shuttle run groups, and it is marginally significant.
Multilevel Analysis of Prognostic Factors for Cognitive Function in Post-Stroke Patients Utami, Sukandriani; Rahardjo, Setyo Sri; Murti, Bhisma; Novika, Revi Gama Hatta; Tamtomo, Didik Gunawan
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.829

Abstract

Background: Stroke is the leading cause of disability and the second leading cause of death worldwide. Post-stroke disability can be in the form of motor, sensory, autonomic, or cognitive impairments. Impaired cognitive function is the leading cause of death and pain in post-stroke patients in the world. Decreased cognitive function is present in more than 70% of post-stroke patients and is associated with disability, independence, and pain. This study aims to analyze the prognosis factors of cognitive function in post-stroke patients.Subjects and Method: This study used a cross-sectional design conducted in 7 hospitals on the island of Lombok from July to August 2024. A total of 200 post-stroke patients were selected using stratified random sampling. The dependent variable in this study was cognitive function examined using the Mini Mental State Examinatio (MMSE) questionnaire. Other independent variables such as age, gender, marital status, pension fund, complications, comorbidities and stroke type were collected using a questionnaire. The data were analyzed using a multilevel double-linear regression model.Results: The prognosis factor of cognitive function in post-stroke patients was age (b=-0.19; CI 95%=-0.29 to -0.10; p=<0.001), marital status (b=-3.80; CI 95%=-6.72 to -0.88; p=0.011), pension fund (b=-5.88; CI 95%= -8.35 to -3.42; p=<0.001), complications (b=-5.37; CI 95%= -7.34 to -3.39; p=<0.001). While sex, comorbidities, and stroke type did not show a significant relationship with the cognitive function of post-stroke patients. Conversely, there was an influence of doctors treating post-stroke patients on cognitive function (ICC=8.76%).Conclusion: Age, marital status, pension funds, and complications are prognostic factors in cognitive function of post-stroke patients. Conversely, there is an influence of doctors who treat post-stroke patients on cognitive function.
Factors Influencing Cervical Cancer Screening Participation in Female: Systematic Review Hastuti, Sri; Wulan, Suryati Kumoro; Widyawati, Melyana Nurul
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.801

Abstract

Background: Cervical cancer is the second leading cause of morbidity and mortality in the world. This can be influenced by several things such as lack of willingness to participate in cervical cancer screening. This review aims to explore factors that influence participation in cervical cancer screening. Subjects and Method: This study is a systematic review with PICO covering: (1) Population: women; (2) Intervention: factors influencing participation; (3) none; (4) level of participation in cervical cancer screening. The databases used are PubMed and JSTOR. Inclusion criteria include full text in Indonesian and English with research subjects in women with cervical cancer. Exclusion criteria in this study were articles published less than five years ago. Results: A total of 21 articles stated that several factors such as interpersonal, intrapersonal, community, organizational, and public policy can influence participation in cervical cancer screening. Conclusion: Intervention strategies based on the reviewed factors need to be improved to reduce cervical cancer morbidity and mortality rates.