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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 273 Documents
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Effect of Ethanol Extract of Rosella Flower Petals (Hibiscus sabdariffa L.) on Healing Cut Wounds in White Rats (Rattus norvegicus) Pratiwi, Ade Dwi; Siahaan , Jekson Martiar; Anto, Endy Juli; Eyanoer, Putri Chairani
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.718

Abstract

Background: Wounds are skin disorders in the form of damage to continuity due to a pathological process, if not treated properly it can cause serious complications such as failure to heal and chronic problems due to untreated wound infections, especially post-operative infections and scar tissue. The next problem is that excessive antibiotics can cause side effects and increase the risk of antimicrobial resistance and delay wound healing. So a new strategy is needed with herbal-based therapy that has the effect of treating infections and does not cause side effects in patients. Subjects and Method: The research was conducted with a post test only randomized control group design to test macroscopic observations of the average size of the wound length, hyperemia and swelling in 30 white Wistar rats (Rattus norvegicus) after receiving ethanol extract of rosella petals (Hibiscus sabdarifa L.). The dependent variables of the study were wound closure time, hyperemia and wound swelling. The independent variable of the research was varying doses of ethanol extract of rosella flower petals (Hibiscus sabdarifa L.) 6%, 12% and 15%. The parameters assessed are the length of the wound and the macroscopic assessment of the wound. Data were analyzed using the Kruskal-Wallis test, p<0.05 was considered statistically significant. Results: Administration of Hibiscus sabdariffa L. 6%, 12% and 15% ethanol extract gel on the 12th day resulted in a significant acceleration of the wound healing process (p=0.024). There was a significant difference between negative control (Mean=3,281 mm ; SD=1,681 mm), positive control (Mean=2,813 mm ; SD=1,106 mm), 6% Rosella flower petal extract gel (Mean=2,916 mm ; SD=1,224 mm ), 12% (Mean=1,290 mm ; SD=1,098 mm), and 15% (Mean=1,035 mm ; SD=0.952 mm) (p=0.024), in the macroscopic assessment there was no significant difference in the wound healing process on day 3, 6, 9, 12 and 15 except for signs of swelling on days 6 (p=0.038) and 9 (p=0.038) which had a significant difference compared to controls. Conclusion: Administration of Hibiscus sabdariffa L. 15% ethanol extract gel had the fastest time in wound closure and healing (Mean=1.035 mm ; SD=0.952 mm) for 12 days (p=0.024), the longest time in wound closure and healing was the negative control (gel placebo) (Mean=0.976 mm ; SD=1.103 mm) namely for 15 days (p=0.158). Keywords: Wound healing, Roselle, Gel Ekstrak Etanol, Hyperemia
Effectiveness of Acupuncture on the Quality of Life in Allergic Rhinitis Patients: Meta Analysis Widiatmaja, I Gusti Bagus Panji; Raharjo, Setyo Sri; Widyaningsih, Vitri
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.719

Abstract

Background:  Allergic rhinitis (AR) is one of the most common health problems experienced by people around the world. WHO ARIA defines allergic rhinitis as a disorder of the nose accompanied by symptoms of sneezing, runny nose, itching, and nasal congestion e after the nasal mucosa is exposed to allergens mediated by immunoglobulin E (IgE). Many studies have proven the impact of acupuncture on the immune system. This study aims to examine and estimate the effectiveness of acupuncture therapy for allergic rhinitis patients based on the results of previous similar studies. Subject and Method: This study is a systematic review and meta-analysis, with PICO as the following Population: allergic rhinitis patients. Intervention: acupuncture therapy. Comparison: sham/placebo acupuncture. Outcome: quality of life. The articles used in this study were obtained from several databases including Google Scholar, MEDLINE/PubMed, Science Direct, Hindawi, Europe PMC and Springer Link. These articles were collected for 1 month. The keywords to search for articles are as follows: "acupuncture for allergic rhinitis" OR "acupuncture for seasonal allergic rhinitis" OR "acupuncture for parenial allergic rhinitis" AND "quality of life" AND “randomized controlled trial". The article included in this study were a full text article with a randomized controlled trial  (RCT)  study design. Quality of life was measured using the Rhinitis Quality of Life Questionnaire (RQLQ). Meta analysis was written using PRISMA flow diagram and analyzed using Review Manager 5.4. Result:  A total of 9 RCT articles with a sample size of 2542 from Germany, Queensland, Victoria, China, and Korea were reviewed in this meta-analysis study. The results of data processing using the RevMan 5.4 application showed the effect of acupuncture therapy on the quality of life of allergic rhinitis patients. Acupuncture was able to lower RQLQ scores (improve quality of life), although it was not statistically significant. Allergic rhinitis patients who obtained acupuncture on average had a quality of life with an RQLQ score of 0.17 units, it was better than those getting sham acupuncture (SMD = -0.17; CI 95% = -0.40 to 0.05; p = 0.120). Conclusion:  There is an effect of acupuncture on the quality of life of allergic rhinitis patients.   Keywords: acupuncture, allergic rhinitis, quality of life, randomized controlled trial
Relationship of Neutrophil Lymphocyte Ratio and Glomerulus Filtration Rate in Diabetic Nephropathy Patients at H. Adam Malik Hospital, Medan, Indonesia Merlin, Asri; Siregar, Jelita; Syafril, Santi
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.720

Abstract

Background: Diabetic nephropathy is a serious complication of diabetes mellitus (DM). The neutrophil-lymphocyte ratio is the result of the relative count of neutrophils divided by the relative number of lymphocytes in diabetic nephropathy patients in % units obtained from routine hematology results using EDTA blood samples and measured by flow cytometry with Sysmex XN-1000, glomerular filtration rate was measured according to the Cockroft-Gault formula. This study aimed to determine the relationship between neutrophil lymphocyte ratio (NLR) and glomerular filtration rate in diabetic nephropathy patients. Subjects and Method:  This was a cross sectional study conducted at H. Adam Malik Hospital, Medan, North Sumatera, Indonesia, from November 2022 – January 2023. 30 diabetic nephropathy patients were selected for this study consecutively. The dependent variable was the glomerular filtration rate. The independent variable was the NLR. Blood sample was taken for a complete blood count and creatinine examination. Data were analyzed using the Spearman test. Results: NLR was negatively associated with eGFR in patients with diabetic nephropathy, but it was statistically non significant (r= -0.25; p= 0.186). Conclusion: NLR is negatively associated with eGFR in patients with diabetic nephropathy, but it is statistically non significant.  Keywords: neutrophil lymphocyte ratio, glomerular filtration rate, diabetic nephropathy
Determinants of Socio-Demographic and Environmental Factors in Helicobacter Pylori Infection Hanif, Ihsan; Tamtomo, Didik Gunawan; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.2.721

Abstract

Background: Helicobacter pylori (H. pylori) infection ranks as one of most frequent human infections in the world. This study aimed to investigate the determinants of H. pylori infection in patients at Universitas Sebelas Maret Hospital. Sebjects and Method: This was an analytic observational with a cross-sectional design. The study was conducted at Universitas Sebelas Maret Hospital, Sukoharjo, Central Java, from November to Desember 2023. A sample of 199 patients was selected for  this  study  by  fixed  disease  sampling.  The  dependent  variable  was H. pylori infection. The independent variables were number of household members, source of water, toilet type, education level, family income, eating habits, smoking status, region type, and waste disposal.  The  data  were  taken  via surveys with questionairre.  Multiple logistic regression was employed for data analysis. Results: The risk of H. pylori infection increased with number of households member ≥5 (AOR= 4.52; 95% CI= 1.78 to 11.45; p = 0.001), water source from well (AOR= 3.74; 95% CI= 1.54 to 9.08; p = 0.003), habits of eating by bare hand (AOR= 4.71; 95% CI= 1.98 to 11.20; p= 0 < 0.001), smoking (AOR= 2.68; 95% CI= 1.11 to 6.49; p = 0.028), and living in urban area (AOR= 2.94; 95% CI= 1.10 to 7.80; p = 0.030). Meanwhile, it also decreased with having education level ≥ high school (AOR= 0.24; 95% CI= 0.10 to 0.57; p < 0.001), having family income ≥ 2,200,000 (AOR= 0.15; 95% CI= 0.06 to 0.37; p < 0.001), and implementing waste disposal system with collected by staff (AOR= 0.26; 95% CI= 0.10 to 0.65; p = 0.004). Conclusion: The risk of H. pylori infection is determined by number of household members, source of water, education level, family income, eating habits, smoking status, region type, and waste disposal. Keywords: determinants, environmental, helicobacter pylori, socio-demographic
Meta Analysis: Factors Affecting Implementation of Self-Care Practice in Diabetes Mellitus Patients Khairiyyah, Alimah Ulfah; Nazalah, Rajba; Aditya, Stefanus; Murti, Bhisma; Marsim, Etanaulia
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.722

Abstract

Background: Diabetes mellitus is a chronic metabolic disorder characterized by high blood sugar levels. If not controlled properly, diabetes mellitus can cause serious complications. Self-care practices are a very important factor in controlling the disease. This study aims to estimate the factors that influence self-care practices in diabetes sufferers.Subjects and Method: This was a systematic review and meta-analysis using PICO format. Population: diabetes patients. Intervention: having diabetes knowledge, high social support, female gender and presence of comorbidities. Comparison: no diabetes knowledge, low social support, male gender and no comorbidities. Outcome: self-care practices. The articles used in this research came from 5 databases, namely Google Scholar and Science Direct. The keywords of the article are "Diabetes Knowledge" AND "Social Support" AND "gender" AND "comorbidities" AND "diabetes" AND "Self-care practice behavior". The articles included in this research are full paper articles, cross-sectional study, publication year range 20172023, and reporting the aORs. Articles were analyzed using the Review Manager 5.4.Results: Female patients (aOR=1.56; 95% CI= 1.04 to 2.34; p= 0.030), high knowledge (aOR= 2.10; 95% CI= 1.27 to 3.46; p= 0.004), strong social support (aOR=1.73; 95% CI= 1.07 to 2.78; p= 0.020), and the presence of comorbidities (aOR=1.20; 95% CI= 0.67 to 2.16; p= 0.540) improved implementation of self-care practices.Conclusion: Female patients, high knowledge, strong social support, and the presence of comorbidities improve implementation of self-care practices. Keywords: factors, diabetes self-care practices, diabetes mellitus
Meta-Analysis: Effect of Hyperbaric Oxygen Therapy on Diabetic Foot Ulcer Recuperation Faried, Faried Effendi Surono; Tamtomo, Didik Gunawan
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.723

Abstract

Background: Diabetes mellitus (DM) is a global phenomenon due to the high morbidity and mortality, especially in developing countries such as Indonesia. An ulcer is a wound and is usually found in patients who experience increased blood sugar and can cause peripheral blood vessel disorders, blood vessel disorders will result in peripheral neuropathy or a combination of both, diabetic ulcers are a condition often experienced by diabetes sufferers. Hyperbaric Oxygen Therapy (HBOT) is a therapy that is considered effective in healing diabetic ulcers and has been proven by many studies conducted. This study aims to analyze the effect of HBO therapy on the improvement of diabetic ulcer wounds. Subjects and Method: This was a systematic review and meta-analysis of primary studies. Article searches were carried out based on the PICO model. Population: diabetic ulcer patients. Intervention: Hyperbaric Oxygen Therapy. Comparison: placebo. Outcome: diabetic ulcers con­dition. Article searches were carried out from Google Scholar, MEDLINE/PubMed, Science Direct, Scopus, Hindawi, BMC, and Spinger Link databases. Keywords used "diabetic foot ulcers" AND "hyperbaric oxygen therapy". The inclusion criteria were full paper, RCT, and reporting risk ratio (RR). Selected studies were analyzed using the RevMan 5.3. Results: 9 RCTs from China, Canada, the Netherlands, Sweden, Egypt, Taiwan, England, and Turkey were selected for meta-analysis. HBO therapy increased diabetic ulcers condition (RR= 1.91; 95% CI= 1.17 to 3.12; p= 0.01). Conclusion: HBO therapy improves diabetic ulcers condition. Keywords: hyperbaric oxygen, diabetic foot ulcer, meta analisis.
The Influence of Working Posture on the Risk of Musculoskeletal Disorders in Batik Makers Aranti, Wulan Adis; Sumardiyono; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.725

Abstract

Background: Complaints of musculoskeletal disorders (MSDs) such as feelings of pain, soreness or soreness in the skeletal muscles felt by batik makers both during work and after work. This study aimed to examine the influence of work posture on the risk of MSDs in batik craftsmen. Subjects and Method: This was a cross-sectional study. Total sample was 200 batik craftsmen was selected by cluster random sampling. The dependent variables were pain and musculoskeletal disorders. The independent variables were age, work posture, work duration, work period, and type of batik craftsmen. Pain was measured using visual analog scale (VAS). MSDs was measured using the Nordic Body Map (NBM). Other variables were collected using questionnaire. The data were analyzed using a multiple logistic regression. Results: Batik craftsmen with non-ergonomic working postures (OR= 2.98; 95% CI=1.27 to 6.99; p= 0.012), age ≥40 years old (OR= 3.45; 95% CI=1.28 to 10.49; p= 0.015), works ≥5 hours/day (OR= 3.52; 95% CI= 1.46 to 8.47; p= 0.012), tenure ≥5 years (OR= 7.04; 95% CI= 3.00 to 16.53; <0.001) significantly increased the risk of MSDs. There was no significant association between type of batik craftsmen and MSDs (OR= 2.76; 95% CI= 0.81 to 9.38; p= 0.102). Nagelkerke R2= 30.8%. Conclusion: Non-ergonomic working postures, age ≥40 years old, works ≥5 hours/day, tenure ≥5 years significantly increase the risk of MSDs. There is no significant association between type of batik craftsmen and MSDs. Keywords: musculoskeletal disorder, pain, work duration, work period, age, batik making
Effect of “Tell Show Do” Method on Dental Anxiety in Pediatrics Dentistry: A Meta Analysis Cahyani, Mey Ditaputri; Widyaningsih, Vitri; Prasetya, Hanung; Simatupang, Nanda Agustian
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.726

Abstract

Background:  Anxiety in children will make it difficult for dentists to perform dental treatment. In dentistry, especially pediatric dentistry, children who are very anxious will avoid examinations and refuse dental treatment. This study aims to analyze the influence of the "tell show do" method in reducing dental anxiety in pediatric patients. Subjects and Method:  This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Search articles through journal databases including: Google Scholar, PubMed, and Springer Link by selecting articles published in 2016 and 2022. The keywords used are (“tell show do” OR “TSD”AND “dental anxiety” OR “anxiety” ) AND (“pediatric dentistry” OR “children”) AND (“RCT” OR “randomized control trial”). The inclusion criteria were full paper articles using the Randomized Controlled Trial (RCT) research method, the results of the analysis used the Mean SD value, the intervention provided was a tell show do, the study subjects were pediatric dental patients at the first visit, with dental anxiety as an outcome. Articles that met the requirements were analyzed using the Revman 5.3 application. Results:  The meta-analysis of 12 articles shows that there is an increasing effect using the tell show do method on reducing dental anxiety. Children who received the tell show do intervention had a dental anxiety level 0.54 units lower than those who did not receive the tell show do, and the effect was statistically significant (SMD 0.54; 95% CI= 0.23 to 0.85; p=0.0007). Conclusion:  The tell show do method has an effect on reducing anxiety in pediatric dental patients.   Keywords: tell show do, dental anxiety, meta-analysis
Meta-Analysis of Acupuncture Therapy for Blood Pressure Reduction in Pre-Elderly with Hypertension Prabowo, Danang Aji; Prasetya, Hanung; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.727

Abstract

Background: Blood pressure tends to increase with age. Hypertension or high blood pressure often occurs in pre-elderly individuals, who are aged between 45-59 years. Acupuncture is one of the therapies with mild side effects that can reduce blood pressure in pre-elderly individuals. This study aims to evaluate the effectiveness of acupuncture therapy in lowering blood pressure in pre-elderly individuals with hypertension based on similar previous research.Subjects and Methods: This study employed a systematic review and meta-analysis based on PICO framework: Population: Pre-elderly individuals with hypertension. Intervention: Acupunc-ture therapy. Comparison: Non-acupuncture therapy. Outcome: Blood pressure. Data were obtained from the PubMed, MEDLINE, Science Direct, BMC, and Google Scholar databases. The search process utilized keywords such as "acupuncture", "hypertension", "Pre elderly", "acupunc-ture for hypertension", AND "acupuncture for blood pressure". Article selection was performed using the PRISMA flowchart, and the results were analyzed using Review Manager 5.3 software.Results: A total of 9 articles originating from the United States, Germany, South Korea, China, India, and Taiwan, with a sample size of 492 subjects, indicated that acupuncture therapy for blood pressure reduction in pre-elderly individuals was not significant for systolic blood pressure (SMD= -0.00; 95% CI= -0.81 to 0.81; p=1.00), but it was significant for diastolic blood pressure (SMD= -1.33; 95% CI= -2.60 to -0.05; p= 0.04).Conclusion: Acupuncture therapy for blood pressure reduction in pre-elderly individuals is not significant for systolic blood pressure, but it is significant for diastolic blood pressure. Keywords: acupuncture, hypertension, pre-elderly, blood pressure, meta-analysis
Effect of Manual Therapy in Reducing Neck Pain in Patients with Hernia Nucleus Polposus Cervicalis Putro, Dimas Liwung Sasongko; Sudaryanto, Wahyu Tri
Indonesian Journal of Medicine Vol. 9 No. 1 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.1.730

Abstract

Background: Herniated Nucleus Pulposus Cervicalis (HNPC) is a medical condition characte­rized by the posterior or posterolateral protrusion of the intervertebral disc, resulting from the degeneration of the fibrous annulus. This protrusion exerts pressure on the nerve roots and spinal cord, leading to the development of neurological disorders. The objective of this study was to assess the efficacy of manual therapy in alleviating neck pain among patients diagnosed with cervical herniated nucleus pulposus. Subjects and Method: A randomized controlled trial was carried out at JIH Hospital in Yogyakarta from August to September 2023. Fourteen patients diagnosed with cervical herniated nucleus pulposus (HNPC) were purposively sampled for the study. Seven patients underwent manual therapy as an intervention, while the remaining seven received standard treatment as the control group. The dependent variable assessed was neck pain, measured using a visual analogue scale (VAS). The independent variable was orthopedic manual physical therapy. The differences in neck pain scores between the two groups were analyzed using an independent t-test. Results: Following the intervention, the pain score in the intervention group (Mean 2.43; SD= 1.13) exhibited a significant reduction compared to the control group (Mean= 4.86; SD= 0.90), with a p-value of 0.001. Conclusion: Orthopedic manual therapy effectively alleviates neck pain in individuals with cervical herniated nucleus pulposus.

Page 19 of 28 | Total Record : 273

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