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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 273 Documents
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Comparison of HbA1c Levels in Normal-Weight and Obese Type 2 Diabetes Mellitus Patients at Dr. Pirngadi General Hospital, Medan, North Sumatra, Indonesia Sagala, Daniela; Nainggolan, Ranatha NH; Sinurat, Suryati; Butar-Butar, Harry; Siahaan , Jekson Martiar
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.802

Abstract

Background: Diabetes mellitus is a collection of metabolic diseases caused by impaired insulin secretion, insulin action, or both so that it has the characteristics of hyperglycemia. Increased will cause a decrease in glucose delivery to the plasma membrane, resulting in insulin resistance in muscle and adipose tissue. This study aimed to compare HbA1c in normal weight and obese individuals with type 2 DM at Dr. Pirngadi hospital.Subjects and Method: This was a cross-sectional study was conducted at Dr. Pirngadi Hospital, Medan, North Sumatera, Indonesia, on May 2022. A sample of 50 patients diagnosed with Type 2 Diabetes Mellitus (T2DM, HbA1c ≥6.5%). The study variables were HbA1c and body mass index (BMI). Independent t-test was used to compare HbA1c levels between normal weight and obese participants.Results: HbA1c in type 2 DM patients with obesity (Mean= 11.49; SD= 0.60) is higher than those with normal weight (Mean= 8.71; SD= 0.34), with p= 0.002.Conclusion: HbA1c in type 2 DM patients with obesity is higher than those with normal weight.
Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy Purwoko, Purwoko; Putro, Bambang Novianto; Pamungkas, Ferdy; Siswanto, Febby Gunawan
Indonesian Journal of Medicine Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.1.424

Abstract

Background: Anesthesia procedure is routinely performed for some painful pediatric oncologic procedures such as lumbar puncture (LP) and bone marrow examination (BME).  Several studies mentioned that fentanyl and remifentanyl are often used as anesthetic agent of this procedure, but none of them compare the recovery time of both agent. This study aims to compare the recovery time of fentanyl and remifentanyl in pediatric patients undergoing methoterexate therapy.Subjects and Method: This was a double-blind randomized controlled trial on 36 patients who underwent intratechal methotrexate chemoterapy under general anesthesia anesthesia in pediatric intervention room of Moewardi General Hospital Surakarta that met inclusion criteria. The dependent variable was recovery time and the independent variable were fentanyl and remifentanyl. The samples were divided into 2, Fentanyl (F) and Remifentanyl (R) group. Recovery time was recorded after the procedure until the subject reached Pediatric Glasgow Comma Scale (PGCS) of 15. Statistical analysis was Mann Whitney U Test using SPSS 25 for Windows.Results: The mean recovery time of F group was 373.39 ± 29.48 seconds, while R group was 124.67±11.55 seconds. There was a significant difference in recovery time between patients in the Fentanyl group and the Remifentanyl group (p= 0.000).Conclusion: Remifentanyl recovery time was significantly faster than with fentanyl in pediatric patients undergoing intrathecal methotrexate chemotherapy.Keywords: Fentanyl, Methotrexate, Outpatient anesthesia, Recovery time, RemifentanylCorrespondence: Ferdy Pamungkas. Anesthesiology Department, Moewardi General Hospital, Surakarta. Jalan Kolonel Sutarto 132 Jebres, Kecamatan Jebres, Surakarta City 57126. Central Java, Indonesia. dr.ferdypamungkas@gmail.com. +6281230269501.Indonesian Journal of Medicine (2022), 07(01): 115-121https://doi.org/10.26911/theijmed.2022.07.01.12
Meta Analysis: Correlation between Diabetes Mellitus and Surgical Wound Infection Fahrezi, Chattrin; Murti, Bhisma; Tamtomo, Didik
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.2.529

Abstract

Background: Surgical wound infections complicate 10-20% of operations with a considerable burden of increasing morbidity, mortality, and health care costs. One third of postoperative deaths are associated with surgical wound infections. The risk of surgical site infection is associated with the presence of risk factors for diabetes mellitus. This causes patients undergoing surgery with diabetes mellitus to have a higher risk of developing surgical site infections. This study aims to examine the effect of diabetes mellitus on the incidence of surgical wound infection.Subjects and Method: This research was conducted using a systematic review design and meta-analysis using PRISMA flow diagrams. The article search was conducted by selecting articles published between the years 2000-2022 which were obtained from several databases of PubMed, Google Scholar, Science Direct, and Springer Link. The keywords used to search for articles were “Diabetes Mellitus”, “Surgical Site Infection”, “cohort”, “Diabetes Mellitus” AND “Surgical Site Infection”, “Diabetes Mellitus” AND “Surgical Site Infection” AND “adjusted odd ratio”. The analysis was carried out using RevMan 5.3 software.Results: Meta-analysis of 9 articles of diabetes mellitus (aOR= 2.54; 95% CI= 1.93 to 3.34; p<0.001) affected the incidence of surgical wound infection.Conclusion: Diabetes mellitus increases the incidence of surgical wound infections.Keywords: diabetes mellitus, surgical wound infectionCorrespondence: Chattrin Fahrezi. Masters Program in Public Health, Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: chattrinfahrezi311@gmail.com. Mobile: 08812­532292.Indonesian Journal of Medicine (2022), 07(02): 122-130https://doi.org/10.26911/theijmed.2022.07.02.01
Effect of Kinesiotaping in Reducing Low Back Pain in Pregnant Women: A Meta-Analysis Handariati, Atik; Pamungkasari, Eti Poncorini; Murti, Bhisma
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.2.535

Abstract

Background: Pregnancy causes physiological changes that affect the musculoskeletal system and usually poses a risk of low back pain. This study aims to analyze the effect of kinesiotaping on reducing low back pain in pregnant women based on the results of a number of previous primary studies.Subjects and Method: This study uses a meta-analysis method with articles searched using the search keywords "Low back pain" OR "pelvic girdle pain" AND "pregnancy" OR "kinesiotaping" OR "kinesio tape" AND "pain reduction" OR "VAS" AND " Randomized Controlled Trial” OR “RCT” from PubMed, google scholar and science direct and processed using RevMan 5.3. The independent variable is kinesiotaping and the dependent variable is low back pain.Results: 9 RCT articles that fit into the inclusion criteria, with a total of 572 samples. Pregnant women with low back pain who received kinesiotaping had an average VAS score of 1.23 units lower than those without kinesiotaping, and the effect was statistically significant (SMD= -1.23; 95% CI -2.30 to -0.16; p= 0.02). In other words, kinesiotaping is effective in reducing low back pain in pregnant women.Conclusion: Kinesio Taping has an effect on reducing low back pain in pregnant women.Keywords: kinesiotaping, low back pain, pregnancy, visual analogue scaleCorrespondence: Atik Handariati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: atikhanda14@gmail.com. Mobile: +628389­5940042.Indonesian Journal of Medicine (2022), 07(02): 161-171https://doi.org/10.26911/theijmed.2022.07.02.05 
Meta Analysis: Relationships of Risk Factors of Physical Activity and Obesity with Premenstrual Syndrome Husna, Erza; Murti, Bhisma; Adriani, Rita Benya
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.2.541

Abstract

Background: Premenstrual syndrome is actually experienced by almost all women wherever they are, but most teenagers think the symptoms they feel do not require further intervention or treat­ment. This study aims to analyze the relationship between physical activity and obesity with pre­menstrual syndrome based on the results of several previous similar primary studies.Subjects and Method: This study was conducted using a meta-analysis study with PICO as follows: P= women aged 17-50 years, I= high physical activity and obesity, C= low physical activity and not obesity, O= premenstrual syndrome. Article searches were conducted using electronic data­bases, namely Pubmed, Google Scholar, Springer Link, Clinical Key, and Proquest. Article searches were conducted using keywords and the Mesh method as follows "physical activity and obesity and premenstrual syndrome", "physical activity and obesity and premenstrual syndrome and adjusted Odds Ratio", "physical activity and obesity and premenstrual syndrome and study cross sectional", " physical activity or obesity or premenstrual syndrome", "physical activity or obesity or premenstrual syndrome or adjusted odds ratio", "physical activity or obesity or premenstrual syndrome or study cross sectional". Articles were analyzed using the Review Manager 5.3 application.Results There are 13 articles from the continents of Africa, Asia, South America, and Europe which include Japan, Palestine, Arabia, Iran, Lebanon, Egypt, Brazil, and Turkey from 2000-2022 which were analyzed using PRISMA flow diagrams. Research studies show that women who do a lot of physical activity have a risk of developing premenstrual syndrome as much as 0.80 times compared to women who do less physical activity (aOR= 0.80; 95% CI = 0.51 to 1.25; p<0.001 ); and obese women had 1.03 times the risk of developing premenstrual syndrome compared with non-obese women (aOR = 1.03; 95% CI = 0.95 to 1.11; p = 0.49).Conclusion: Physical activity can reduce the risk of premenstrual syndrome and obesity can increase the risk of premenstrual syndrome.Keywords: physical activity, obesity, premenstrual syndromeCorrespondence: Erza Husna. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java, Indonesia. Email: erza.husna@gmail.com. Mobile: +6285747580999.Indonesian Journal of Medicine (2022), 07(02): 219-231https://doi.org/10.26911/theijmed.2022.07.02.10
Correlation between Mortality of COVID-19 Patients with Hypertension and Thorax Radiography Treated in the Intensive Care Unit of Dr. Moewardi Hospital Nurhidayati, Faiza Salsabila; Soewondo, Widiastuti; Dewi, Ratih Tri Kusuma; Putro, Prasetyo Sarwono
Indonesian Journal of Medicine Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.3.544

Abstract

Background: Coronavirus 2019 or COVID-19, caused by the new SARS-CoV2 virus, has become a pandemic and attacked more than 200 countries, including Indonesia. The most comorbid disease in COVID-19 patients was hypertension. Chest radiography can predict prognosis and mortality in COVID-19 cases and one of the methods that can be used for chest radiographic assessment is the Brixia Score, specifically designed for COVID-19 patients to measure and analyze the severity of lung abnormalities in patients with COVID-19. This study aimed to find the correlation between the mortality of COVID-19 patients with hypertension and chest radiography using the Brixia Score treated in the intensive care unit (ICU) of Dr. Moewardi Hospital.Subjects and Method: This study used an analytic observational study with a cross-sectional approach. The subjects were 84 COVID-19 patients with hypertension who met the exclusion and inclusion criteria. The independent variable is chest radiography and dependent variable is mortality. Sampling was collected by purposive sampling and the data obtained were analyzed using the contingency coefficient test.Results: There was a significant correlation between the mortality of COVID-19 patients with hypertension and chest radiography as assessed using the Brixia Score (p<0.001). The youngest patient was 20 years old and the oldest was 87 years old.Conclusion: There was a correlation between the mortality of COVID-19 patients with hypertension and chest radiography treated in the ICU RSUD Dr. Moewardi, Surakarta.Keywords: COVID-19, mortality, hypertension, chest radiography, Brixia Score, intensive care unitCorrespondence: Widiastuti Soewondo. Faculty of Medicine Universitas Sebelas Maret Surakarta. Jl. Ir. Sutami 36A, Surakarta 57126, Indonesia. Email: Widiastuti.sprad56@staff.uns.ac.id. Mobile: 082134368592.Indonesian Journal of Medicine (2022), 07(03): 269-277https://doi.org/10.26911/theijmed.2022.07.03.03 
Atypical Spinal Tuberculosis of Upper Thoracic Spine: A Rare Case Report Wiguna, I Gusti Lanang Ngurah Agung Artha; Wondany, Ryan Putra; Arimbawa, Ida Bagus Gede
Indonesian Journal of Medicine Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.3.547

Abstract

Background: Tuberculous infection is one of the most common pulmonary infection in developing countries, including Indonesia. Spinal tuberculosis is one of the most common extra¬pulmonary tuberculosis manifestation, accounting for 5% of all extrapulmonary spread, and 50% of all osteoarticular involvement. The aim of this study is to evaluate and how diagnosis and treatment to prevent over or under-diagnosis and explain about excellent management without any late complication further.Case Presentation: A 20-year-old male with a history of weakness of both of his leg for 20 days prior to admission. From these examinations, patient was then diagnosed with pathological fracture 2nd thoracic vertebral body suspected due to atypical spinal tuberculosis. Patient was then undergone surgical debridement, decompression, stabilization and fusion.Results: Patient was then undergone surgical debridement, decompression stabilization fusion. During the exposure at level C6 through Th4, no abscess was found. Transpedicular debridement at level Th2 was then done after the insertion of pedicle screws at level C6-Th1 and Th3-Th4, and again no abscess was present, however, a granulomatous mass was present on the location of 2nd thoracic vertebral body, located on the anterior right side of the spinal cord outside the dura mater.Conclusion: Atypical presentation of spinal tuberculosis with the sole clinical manifestation of neurological deficit below affected level. The definitive treatment such as surgical debridement, stabilization and fusion must be consider.Keywords: spinal, infection, tuberculosis, young patient.Correspondence: I Gusti Lanang Ngurah Agung Artha Wiguna. Division of Spine, Department of Orthopaedic & Traumatology, Prof. I.G.N.G Ngoerah Hospital, Faculty of Medicine, Udayana University, Bali, Indonesia. Email:lanangwiguna20021979@gmail.com. Mobile: 0811388859.Indonesian Journal of Medicine (2022), 07(03): 289-297https://doi.org/10.26911/theijmed.2022.07.03.05
The Relationship between Self-Care Agency and the Level of Disability to Patient with Leprosy at Daha Husada Hospital, Kediri Widyowati, Agustin; Hapsari, Ika Ratna; Nuridayanti, Anik
Indonesian Journal of Medicine Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2022.7.3.557

Abstract

Background: Leprosy has a tendency to have physical impacts with disability on sufferers so that it affects community stigma, social isolation, welfare to quality of life. One of the efforts to prevent disability with good self-care. The objective was to determine the relationship between self-care agency and the level of disability to patients with leprosy at Daha Husada Hospital Kediri.Subjects and Method: A cross sectional study was conducted in Daha Husada Hospital, Kediri, East Java, in March, 2021. A sample of 115 patients was selected by purposive sampling. The dependent variable was the level of disability. The independent variable was self-care agency. Data were collected using questionnaires and observation sheets with ordinal scale, then analyzed using statistical test of Spearman's Rho.Results: Less ability of leprosy patients in self care agency, the greater the level of disability (r= 0.62; p<0.001).Conclusion: Less ability of leprosy patients in self-care agency, the greater level of disability. Patient are needed to improve the awareness in self-care activities and follow counseling in health services.Keywords: self care agency, the level of disability, patient with leprosy.Correspondence: Agustin Widyowati. STRADA Indonesian Institute of Health Sciences Kediri. Jl. Manila No.37, Tosaren, Kec. Pesantren, Kota Kediri, East Java 64123. Email: agustwidy@gmail.com. Mobile: +62857-3539-9728.Indonesian Journal of Medicine (2022), 07(03): 344-349https://doi.org/10.26911/theijmed.2022.07.03.11
A Rare Case Of Retinal Arterial Microaneurysm: Clinical Features And Diagnostic Insights Yuna, Uray Nabila; Ihsan, Grimaldi; Virgana, Rova; Kartasasmita, Arief S.; Iskandar, Erwin; Widyanatha, Made Indra
Indonesian Journal of Medicine Vol. 10 No. 1 (2025)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.1.773

Abstract

Background: In Retinal Arterial Macroaneurysms (RAM), the central retinal artery suffers from acquired focal hypertension. Clinical manifestations of the disease are diverse and easily misdiagnosed. Several imaging modalities may be used in order to confirm the diagnosis of RAM. This article aims to describe the clinical features and method of diagnosis of an uncommon case of retinal artery microaneurysm. Case report: A 57-year-old woman presented with a progressive loss of vision in her right eye months prior. Visual acuity in the right eye was 0.8 log 13. Upon funduscopic inspection of the right eye, firm exudates with low tortuosity and submacular hemorrhage were observed. The right eye’s OCTA revealed a localized expansion and significant constriction with twisted blood vessels on the reverse side of the deformed vessel, while the OCT of the macula revealed submacular hemorrhage. The patient was diagnosed with ruptured retinal Arterial Macroaneurysm or Macular Telangiectasia Type I and Retinopathy Hypertensive Grade II of both eyes, No Diabetic Retinopathy of both eyes with Diabetes Mellitus and Hypertension. The right eye of the patient received concentrated laser photocoagulation and an intravitreal injection of anti-VEGF. Conclusion: RAM is an acquired vascular disease defined by restricted, fusiform, or saccular dilation in the first three arteries of the main retinal artery. Retinal microaneurysms can be diagnosed with various imaging modalities. Ram may be treated with intravitreal anti-VEGF drugs, combination therapy, or laser photocoagulation.
Association of Antiretroviral Regimens and CD4 Counts with Dyslipidemia in HIV Patients: Implications for Metabolic Management Rosandy, Milanitalia Gadys; Candradikusuma, Didi; Yudha, Nyoman Satvika Dharma
Indonesian Journal of Medicine Vol. 10 No. 1 (2025)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.1.797

Abstract

Background: Dyslipidemia, a key risk factor for cardiovascular disease, is prevalent among people living with HIV/AIDS receiving antiretroviral therapy. This study aims to evaluate the impact of different ART regimens on lipid profiles in HIV patients and identify regimens with better outcomes in lipid profile levels. Subjects and Method: An observational study was conducted from June to August 2024 at Dr. Saiful Anwar Regional General Hospital, Malang, Indonesia. Participants were recruited using consecutive random sampling, including HIV patients on ART for at least three months. Independent variables included ART regimens and CD4 counts, while the dependent variable was dyslipidemia status. Data were collected via demographic forms, medical record reviews, and lipid profile analysis. Statistical analysis was performed using chi-square and t-tests, with significance set at p < 0.05. Results: Of the 110 participants, 38.2% were identified with dyslipidemia. The highest dyslipidemia rates were observed in patients using the Duviral Alluvial regimen (80.0%), followed by Duviral Neviral (71.4%). Newer regimens, TLD and TLE, were associated with lower dyslipidemia rates (31.3% and 36.0%, respectively; p = 0.045). A significant association was also noted between dyslipidemia and CD4 counts, with dyslipidemic patients showing higher mean CD4 counts (560.29 cells/μL) compared to non-dyslipidemic individuals (378.40 cells/μL; p = 0.009). Conclusion: Newer ART regimens such as TLD and TLE are associated with better lipid profile outcomes and lower dyslipidemia risk compared to older regimens. Higher CD4 counts may reflect an increased risk of lipid abnormalities, emphasizing the need for lipid monitoring and regimen optimization in HIV care.

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