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MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan

APKKM
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Published by Universitas Muhammadiyah Semarang

ISSN : 24070505 EISSN : - DOI : https://doi.org/10.26714/magnamed

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Magna Medica is a medical journal of APKKM contains papers and scientific articles created as a form of realization Tridharma college. The journal is published every six months, April and October of three articles in the form of: - Research article - Case report - Literature review The scope of this journal is all the field of medicine such as: -Internal medicine (including Pulmonary medicine and cardiovascular medicine) -Surgery (including urology, orthopaedic and traumatologic, plastic surgery, neurosurgery) -Anesthesia and Emergency Medicine -Neurology -Dermatology -Obstetric and Gynecologic -Forensic and Medicolegal -Clinical Pathology -Anatomical Pathology -Psychiatric -Ophthalmology -Otolaryngology -Pediatric -Radiology -Microbiology and parasitology -Basic Science of Medicine (including biochemistry, physiology, anatomy and Histology) -Public health and Health Management

Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran

Articles 222 Documents

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Myoepithelial Carcinoma Spindle cell type, Clear cell type, and Plasmacytoid type: Serial Kasus A Case Series of Myoepithelial Carcinoma Spindle cell type, Clear cell type, and Plasmacytoid type Lestari, Dian Yuliartha; Fauziah, Dyah
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 2, No 4 (2018): August
Publisher : Universitas Muhammadiyah Semarang

Myoepithelial Carcinoma adalah salah satu keganasan kelenjar liur yang sangat jarang terjadi, dimana terdiri dari komponen sel-sel myoepithelial yang berdifferensiasi sebagai sel spindle, sel jernih (clear), sel epitheloid, sel stelate, maupun sel plasmacytoid.Kami melaporkan 3 kasus myoepithelial carcinoma yang didiagnosis di Rumah Sakit Dr. Soetomo Surabaya dalam kurun waktu 4 tahun terakhir dengan tiga tipe yang berbeda, yaitu; spindle cell type, clear cell type, dan plasmacytoid type. Dua kasus terjadi pada kelenjar parotis, lainnya pada kelenjar submandibula, dimana ketiganya terjadi pada wanita dengan rentang usia 45-76 tahun. Keluhan saat datang berobat adalah timbul benjolan semakin membesar secara perlahan dan tidak menimbulkan nyeri. Hasil pemeriksaan histopatologis menyatakan suatu carcinoma mengesankan myoepithelial carcinoma. Hasil pemeriksaan immunohistokimia smooth muscle actin (SMA)dan S100 mayoritas menunjukkan hasil yang positif, dimana menyokong diagnosis suatu myoepithelial carcinoma Myoepithelial Carcinoma is one of the most rare salivary gland malignancies, which consists of components of myoepithelial cells that differentiate as spindle cells, clear cells, epitheloid cells, stellate cells, and plasmacytoid cells.We report 3 cases of myoepithelial carcinoma diagnosed at Dr. Hospital. Soetomo Surabaya in the last 4 years with three different types, namely; spindle cell type, clear cell type, and plasmacytoid type. Two cases occurred in the parotid gland, the other in the submandibular gland, of which all three occurred in women with a range of45-76 years old. Complaints when coming for treatment is a lump that grows slowly and does not cause pain. The results of histopathological examination revealed a carcinoma suggesting myoepithelial carcinoma. The results of the immunohistochemical examination of smooth muscle actin (SMA) and S100 the majority showed positive results, which supported the diagnosis of myoepithelial carcinoma.

Antibiotik Profilaksis Pada Penyakit Jantung Musa Ghufron; Muhammad Perdana Airlangga
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 6, No 1 (2019): February
Publisher : Universitas Muhammadiyah Semarang

Prophylactic Antibiotics in Heart DiseaseInfective endocarditis (IE) is an uncommon but lifethreatening infection. Despite advances in diagnosis, antimicrobial therapy, surgical techniques, and management of complications, patients with IE still have high morbidity and mortality rates related to this condition. Since the last American Heart Association (AHA) publication on prevention of IE in 1997, many authorities and societies, as well as the conclusions of published studies, have questioned the efficacy of antimicrobial prophylaxis to prevent IE in patients who undergo a dental, gastrointestinal (GI), or genitourinary (GU) tract procedure and have suggested that guidelines should be revised

Hubungan Tingkat Pendidikan dan Pengetahuan Masyarakat dengan Perilaku Pencegahan Demam Berdarah dengue di Desa Kemiri, Kecamatan Jayakerta, Karawang tahun 2016 Putri, Rezki; Naftassa, Zaira
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 4 (2017): February
Publisher : Universitas Muhammadiyah Semarang

Relationship between Education Level and Community Knowledge with Dengue Hemorrhagic Fever Prevention Behavior in Kemiri Village, Jayakerta District, Karawang in 2016Latar belakang: Demam berdarah Dengue (DBD)merupakan masalah kesehatan di Indonesia yang sampai saat ini cenderung menunjukkan peningkatan dalam jumlah penderita maupun daerah persebaran. Terdapat berbagai kendala untuk menurunkan jumlah penderita DBD, diantaranya kurangnya pengetahuan masyarakat tentang penularan DBD serta pengetahuan untuk mencegah infeksi DBD. Berdasarkan Dinas Kesehatan Kabupaten Karawang tercatat kasus Demam Berdarah Dengue selama Januari - Desember 2015 mencapai 480 kasus DBD; di Desa Kemiri Kabupaten Karawang sebanyak 60 penderita. Tujuan: Penelitian ini bertujuan untuk mengetahui tingkat pendidikan dan pengetahuan masyarakat mengenai perilaku pencegahan DBD di Desa Kemiri.Metode: Penelitian dilakukan terhadap masyarakat di desa Kemiri pada bulan Oktober - November tahun 2016 dengan menggunakan desain studi crosssectional. Pengambilan sampel sebanyak 100 responden dengan teknik random sampling. Instrumen yang digunakan adalah kuesioner dengan analisis data menggunakan uji Chi-square.Hasil: Berdasarkan 100 sampel didapatkan 55,0% responden memiliki pengetahuan baik dan responden dengan pengetahuan kurang sebanyak 35,0%, responden dengan pendidikan tinggi sebanyak 78,0% dan responden dengan pendidikan rendah sebanyak 22,0%, responden yang melakukan tindakan pencegahan baik sebanyak 63,0% sedangkan responden yang melakukan pencegahan kurang sebanyak 37,0%. Hasil analisis bivariat menunjukkan hubungan yang signifikan antara variabel tingkat pendidikan dengan perilaku pencegahan (p=0,008), dan terdapat hubungan yang signifikan antara variabel tingkat pengetahuan dengan perilaku pencegahan.Simpulan: Melalui penyuluhan sebagai upaya pembekalan pengetahuan bagi masyarakat diharapkan kepedulian masyarakat serta pemahaman yang lebih baik tentang DBD. Background: Dengue Haemorrhagic Fever has been a health problem in Indonesia until recently, thus, tend to show an increase in the number of patients and the spread area. Various difficulties still blocking the way to bring down the amount of morbidities; public ignorance regarding dengue fever caused lack of awareness in the prevention of dengue fever itself. Based on Dinas Kesehatan Kabupaten Karawang, the DHF morbidities showed 480 people from Januari to Desember 2015, and Desa Kemiri data were 60 people infected.Objective: This study aimed correlation of education level and knowledge of people or occupants in Desa Kemiri, Kertajaya, Karawang regardless of DHF prevention. Methods: This study held on Oktober to November 2016 based on cross-sectional study. All 100 respondents were occupants of Desa Kemiri, with randomized sampling system. Questionnaires were given as instruments and then analized by Chi–square.Result:The results showed that out of 100 respondents, 55% were having good knowledge of DHF, and 35% were not; 78% respondents were well educated, while 22% were not; 63% respondents showed good DHF prevention, and 37% were not. There were also significancy results showed by bivariate data analysis between variable of education level and prevention of DHF (p=0.08), along with variable of knowledge level and prevention of DHF.Conclusion: The awareness and aknowledgement of DHF can be well achieved through public presentation as a simple way to make people understood about the DHF.

Hubungan Self Assessment Dengan Kompetensi Klinik Mahasiswa Kedokteran Novitasari, Andra; Djunaidi, Djunaidi
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February
Publisher : Universitas Muhammadiyah Semarang

Relationship between Self Assessment and Clinical Competence of Medical StudentsBackground: One area of competence that must be possessed by a doctor is introspection and self-development. Self-assessment is an important component in self-development. Students who have been able to carry out self-assessment on one component of clinical competence well are not necessarily able to carry out self-assessment by integrating all components of clinical competence.Objective: This study aims to analyze the relationship between self-assessment and clinical competence of medical students.Methods: This study is an observational study with a cross sectional design which was analyzed by statistical tests which included univariate analysis and bivariate analysis of the variables between the existence of self-assessment and clinical competence of medical students. The sample in this study was 60 7th semester medical students. Sampling was done by consecutive sampling technique.Results: Bivariate analysis using Chi-Square test showed that there was no significant relationship between self-assessment and clinical competence of medical students (p=0.643).Conclusion: Self-assessment of clinical competence has not been able to provide an overview of the actual clinical competence possessed by students Latar Belakang: Salah satu area kompetensi yang harus dimiliki oleh seorang dokter adalah mawas diri dan pengembangan diri. Self assessment merupakan komponen penting dalam pengembangan diri. Mahasiswa yang sudah mampu melakukan self assessment pada satu komponen kompetensi klinik dengan baik, belum tentu mampu melakukan self assessment dengan mengintegrasikan seluruh komponen kompetensi klinik. Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan antara self assessment dengan kompetensi klinik mahasiswa kedokteran. Metode Penelitian: Penelitian ini merupakan studi observasional dengan desain cross sectional yang dianalisis dengan uji statistik yang meliputi analisis univariat, dan analisis bivariat terhadap variabel antara adanya self assessment dan kompetensi klinik mahasiswa kedokteran. Sampel dalam penelitian ini sebanyak 60 mahasiswa kedokteran semester ke-7. Pengambilan sampel dilakukan dengan teknik consecutive sampling. Hasil Penelitian: Analisis bivariat menggunakan uji Chi-Square menunjukkan bahwa tidak ada hubungan yang signifikan antara self assessmen dan kompetensi klinik mahasiswa kedokteran (p=0.643). Kesimpulan: Self assessment terhadap kompetensi klinik belum dapat memberikan gambaran kompetensi klinik yang sebenarnya dimiliki oleh mahasiswa

Hubungan Perilaku Perawatan Rambut Terhadap Kejadian Dermatitis Seboroik pada Siswi SMA Muhammadiyah 1 Semarang Ayu, Bevi; Indrastiti, Retno; Ratnaningrum, Kanti
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 2, No 4 (2018): August
Publisher : Universitas Muhammadiyah Semarang

The Relationship of Hair Care Behavior on the Incidence of Seborrheic Dermatitis in SMA Muhammadiyah 1 Semarang StudentsLatar Belakang: Dermatitis seboroik terjadi pada setengah populasi global remaja dan pasca-pubertas. Dermatitis seboroik menjadi salah satu masalah pada pengguna hijab, oleh karena itu peneliti ingin mengetahui perilaku perawatan rambut terhadap kejadian dermatitis seboroik pada siswi SMA Muhammadiyah 1 Semarang.Metode: Penelitian ini merupakan observasional analitik dengan pendekatan cross sectional. Pengambilan sampel menggunakan rumus slovin dengan teknik simpel random sampling. Populasi sampel merupakan Siswi SMA Muhammadiyah 1 Semarang kelas 2 dan kelas 3 dengan kriteria inklusi siswi yang konsisten menggunakan hijab selama berada di sekolah dan di kehidupan sehari-hari, siswi berusia 15-17 tahun, sedangkan kriteria ekslusi meliputi siswi yang menderita penyakit kulit bagian kepala seperti Tinea Capitis, Psoriasis, Alopecia Areata, dan Pedikulosis, serta siswi yang pernah mengalami post trauma pada kepala (Trikotilomania, Alopecia dan siswi yang mengalami post operasi pada kepala. Data penelitian menggunakan data primer dengan pemeriksaan fisik menggunakan loop dan wawancara dengan kuesioner. Uji statistik penelitian menggunakan uji chi-square dan regresi logistik.Hasil: Dari 66 siswi, didapatkan hasil bahwa 84,8% (50 siswi) mengalami dermatitis seboroik. Pengunaan handuk (p=0,016; ß=3,429), frekuensi mengganti handuk (p0,022; ß=2,678), dan cara menyimpan handuk (p=0,018; ß=2,829) berpengaruh pada kejadian dermatitis seboroikSimpulan: Terdapat hubungan yang signifikan antara perilaku perawatan rambut terhadap dermatitis seboroik pada siswi SMA Muhammadiyah 1 Semarang. Background: Seborrhoeic dermatitis occurs in half the global population of post-puberty adolescents. Seborrhoeic dermatitis is one of the problems in hijab users, therefore researchers want to know behavior of hair treatment to the occurrence of seborrheic dermatitis in students of High School Muhammadiyah 1 (SMA Muhammadiyah 1) Semarang.Method: an analytic observational study with cross sectional. Sampling using slovin formula with simple random sampling technique. The sample population is studentsof SMA Muhammadiyah 1 Semarang class 2 and 3 with inclusion criteria consistent by using hijab during school and everyday life, female students aged 15-17 years;exclusion criteria include students suffering from skin diseases of the head such as Tinea Capitis, Psoriasis, Alopecia Areata, and Pediculosis; and students who have experienced post trauma to the head (Trichotillomania, Alopecia) and postoperative students on the head. Research data using primary data by physical examination using loop and interview with questionnaire. The research statistic used chi-square test and logistic regression.Results: From 66 female students, it was found that 84.8% (50 girls) had seborrheic dermatitis. use of towel (p = 0.016; ß = 3.429), the frequency of towel replacing (p0.022; ß= 2,678), and the way of towel (p= 0,018; ß = 2,829) had significant on occurrence of seborrhoeic dermatitis.Conclusion: There is a significant relationship between hair treatment behavior against seborrheic dermatitis in high school students of Muhammadiyah 1 Semarang

Pengembangan Alat Ukur Khusuk Sholat Dalam Kaitan Pengaruh Positifnya Bagi Kesehatan Romadhon, Yusuf Alam
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 6, No 1 (2019): February
Publisher : Universitas Muhammadiyah Semarang

Development of Measuring Instruments for Prayers in Relation to its Positive Effect on HealthLatar belakang: Khusyuk dalam sholat merupakan pengalaman personal yang belum banyak dikaji. Banyak penelitian eksperimental menunjukkan pengaruh positif sholat bagi kesehatan, tetapi penelitian skala luas mendapatkan hasil sebaliknya di Indonesia.Tujuan: Penelitian ini untuk mengembangkan instrumen pengukuran khusyuk sholat dalam kaitan pengaruh positifnya bagi kesehatan yang berbahasa Indonesia penelitian ini terdiri dari 3 fase.Metoda: Fase I: eksplorasi literatur dan studi kualitatif untuk mendapatkan konsep kunci dan operasionalisasi konsep kunci. Fase II: pengembangan dan penajaman item berdasarkan operasionalisasi konsep kunci. Fase III: studi pendahuluan dan analisis statistik.Hasil: eksplorasi literatur dan studi kualitatif didapatkan 4 domain konsep utama dan 11 sub domain tentang khusyuk; 1) status khusyuk terdiri dari a) induksi perubahan kesadaran karena niat, b) Isolasi mental perubahan kesadaran diri, c) peragaan dialog mental dengan Allah, d) faktor pemampu khusyuk, e) pengendalian mind wandering; 2) prasyarat keyakinan dan God attachment terdiri dari a) keyakinan kuat bertemu Allah dan b) God attachment; 3) atmosfer spiritual terdiri dari a) kesiapan hati, kelonggaran waktu dan suasana tempat dan b) kondisi psikologis tertentu dan kematangan spiritual; 4) dampak khusyuk terdiri dari a) restrukturisasi kognitif peristiwa kehidupan dan b) perasaan segar, tenang dan rileks. Pengembangan item selanjutnya direview oleh pakar agama dan psikiatri untuk mendapatkan validitas isi.Simpulan: Setelah mengkoreksi item-item dengan korelasi item–total rendah, didapatkan 42 item dengan Cronbach's Alpha .945. Background: Devotion in Islamic prayer is a personal experience that has not been widely studied. Many experimental studies have shown a positive effect on Islamic prayer for health, but large-scale research has the opposite results in Indonesia. Objective: This study are develop instruments for measuring solemn prayer inrelation to its positive influence on health in Indonesian Method: Three research phases were carried out. Phase I: literature exploration and qualitative studies to get key concepts and operationalize key concepts. Phase II: development and sharpening of items based on the operationalization of key concepts. Phase III: preliminary study and statistical analysis. Result: The literature exploration and qualitative studies obtained 4 main concept domains and 11 sub domains about solemn; 1) solemn status consists of a) induction of change in consciousness due to intention, b) Isolation of mental changes in self-awareness, c) demonstration of mental dialogue with God, d) solemn enabling factors, e) mind wandering control; 2) the prerequisites for belief and the God attachment consists of a) strong belief in meeting God and b) God attachment; 3) the spiritual atmosphere consists of a) heart readiness, looseness of time and atmosphere of the place and b) certain psychological conditions and spiritual maturity; 4) solemn effects consist of a) cognitive restructuring of life events and b) feeling refreshed, calm and relaxed. Conclusion: The item development was then reviewed by religious and psychiatric experts to obtain content validity. After correcting items with a low total-item correlation, 42items were obtained with Cronbach's Alpha .945.

Efektivitas Ekstrak Kulit Manggis Sebagai Terapi Adjuvan Terhadap Perbaikan Gejala dan Tanda Klinis serta Kualitas Hidup Pasien Rinitis Alergi Kadarullah, Oke; Lasminingrum, Lina; Sumarman, Iwin
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 4 (2017): February
Publisher : Universitas Muhammadiyah Semarang

The Effectiveness of Mangosteen Peel Extract as Adjuvant Therapy for Improvement of Clinical Symptoms and Signs and Quality of Life of Allergic Rhinitis PatientsLatar belakang: Rinitis alergi (RA) merupakan penyakit inflamasi di mukosa hidung yang diperantarai IgE setelah paparan alergen. Polusi dapat memperberat inflamasi alergi. Terapi RA ditujukan untuk memperbaiki gejala, mencegah perburukan, dan meningkatkan kualitas hidup. Ekstrak kulit manggis merupakan herbal yang lazim digunakan sebagai terapi adjuvan/tambahan dengan efek antiinflamasi dan antioksidan. Kapasitas antioksidannya lebih tinggi dibandingkan buah lain. Tujuan penelitian ini adalah untuk menilai perbaikan gejala klinis, tanda klinis, serta kualitas hidup pada RA menetap sedang berat. Metode: Penelitian ini merupakan quasi experimental randomized trial open label pre and post test design. Penelitian berlangsung di poliklinik Ilmu Kesehatan Telinga Hidung Tenggorok Bedah Kepala Leher Rumah Sakit Dr. Hasan Sadikin Bandung bulan September −November 2013. Kelompok kontrol mendapat terapi standar berupa tablet loratadin dan kortikosteroid intranasal, sedangkan kelompok perlakuan diberi tambahan kapsul ekstrak kulit manggis selama 14 hari. Diagnosis berdasarkan anamnesis , pemeriksaan fisik dan tes kulit tusuk. Lalu dinilai skor gejala hidung semikuantitatif Weeke, Davis dan Okuda (TNSS), skor nasoendoskopi adaptasi Lund Kennedy, serta skor gangguan kualitas hidup RQLQ dari Juniper. Data dianalisis menggunakan uji Wilcoxon dan Mann Whitney.Hasil: Dari 34 subjek terbagi dalam dua kelompok, perbaikan skor TNSS, skor nasoendoskopi, dan skor RQLQ didapatkan hasil yang signifikan (p<0,05) pada tiap kelompok pascaterapi. Namun perbandingan seluruh variabel pemeriksaan pasca terapi antara kedua kelompok tidak siginifikan (p>0,05).Simpulan: Pemberian kapsul ekstrak kulit manggis sebagai terapi adjuvan tidak efektif pada pasien RA menetap derajat sedang berat dalam meningkatkan efektivitas terapi standar. Background: Allergic rhinitis (RA) is an inflammatory disease in the IgE-mediated nasal mucosa after allergen exposure. Pollution can aggravate allergic inflammation. RA therapy is aimed at improving symptoms, preventing deterioration, and improving quality of life. Mangosteen skin extract is an herb commonly used as adjuvant / additional therapy with anti-inflammatory and antioxidant effects. Antioxidant capacity is higher than other fruit. The purpose of this study was to assess the improvement of clinical symptoms, clinical signs, and quality of life in moderate to severe RA.Methods:This research is a quasi experimental randomized trial of open label pre and post test design. The research took place in the polyclinic of Ear Nose Throat Surgery Head Surgery of Neck Hospital. Hasan Sadikin Bandung in September-November 2013. The control group received standard therapy in the form of loratadine tablet and intranasal corticosteroid, while the treatment group was given additional mangosteen leaf extract capsule for 14 days. Diagnosis based on anamnesis, physical examination and puncture skin test. Then assessed the semiticivity of Weeke, Davis and Okuda (TNSS) nose score, Lund Kennedy's adaptation nasoendoskopi score, and Juniper's RQLQ quality-disruption score. Data were analyzed using the Wilcoxon and Mann Whitney tests.Results: The 34 subjects divided into two groups, improvement of TNSS score, nasoendoskopi score, and RQLQ score showed significant results (p <0.05) in each post-therapy group. However, the comparison of all post-therapy examination variables between the two groups was not significant (p> 0.05).Conclusion: The administration of mangosteen skin extract capsules as adjuvant therapy is not effective in patients with moderate to severe RA in improving the effectiveness of standard therapy.

Strategi Bisnis RSU PKU Muhammadiyah Blora Melalui Pemetaan Faktor Internal dan Eksternal Lahdji, Aisyah
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February
Publisher : Universitas Muhammadiyah Semarang

Business Strategy of PKU Muhammadiyah Blora Hospital through Mapping of Internal and External FactorsThe changing business environment demands hospital to adjust. the arrangement of strategic planning is required as of the hospital effort to answer the challenge off change. Therefore, the study highlighted in this research relates to the development of business strategy add the General Hospital of PKU Muhammediyah Blora. This research is an operational research conducted with descriptive approach on the service strategy planning in the public hospital (RSU) PKU Muhammadiyah Blora at the year 2016-2020. The result of this research direct the that RS PKU Muhammediyah Blora neat to develop service strategy planning. The developed service strategy planning refers to the result of focus group discussion (FGD) done in this research which had mapped out the strength and weakness owned by General Hospital of PKU Muhammadiyah Blora. The formulated service strategy planning include improving the quality of human resources through education and training programs, specialist scholarship programs for physicians, increasing partnership with specialist physician partners, adding capacity / number of beds, as well as improving service quality. the implementation of developed services strategy planning requires a commitment from all levels off staff in General Hospital of PKU Muhammadiyah Blora.

Pengaruh Pemberian Etanol Secara Akut Terhadap Memori Kerja Pada Tikus (Rattus norvegicus) Basuki, Rochman; Anggraini, Merry Tiyas
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February
Publisher : Universitas Muhammadiyah Semarang

Effect of Acute Ethanol Administration on Working Memory in Rats (Rattus norvegicus)Background: Acute administration of ethanol can cause neurological disorders, including the prefrontal cortex (CPF) because ethanol is neurotoxic. One of the disorders is a decrease in memory function.Objectives: This study was to determine the effect of acute ethanol administration on spatial working memory in rats.Methods: This experimental study with a posttest-only-randomized control design involved 20 rats (Rattus norvegicus) which were divided into 4 groups (K, P1, P2 and P3) each of 5 animals. Groups P1, P2 and P3 respectively were given 15% intra-peritoneal ethanol at doses of 1, 2 and 3 g/kg/day for 20 days. Memory performance is measured by 8-arm radial maze with the parameter Number of Error, namely the number of type A errors divided by the number of arms entered.Result : After 20 days of ethanol administration, spatial working memory between groups was tested by Kruskal Wallis. The results showed that there was no significant difference, namely 0.070 (p>0.05).Conclusion: There is no significant relationship between spatial working memory in rats after acute administration of ethanol.Latar belakang: Pemberian etanol secara akut dapat menyebabkan gangguan neurologis, diantaranya cortex prefrontalis (CPF) karena etanol bersifat neurotoksik. Salah satu gangguannya berupa penurunan fungsi memori.Tujuan Penelitian: Penelitian ini untuk mengetahui adanya pengaruh pemberian etanol secara akut terhadap memori kerja spasial pada tikus.Metode Penelitian: Penelitian eksperimen dengan desain posttest-only-randomized control ini melibatkan 20 tikus (Rattus norvegicus) yang dibagi menjadi 4 kelompok (K, P1, P2 dan P3) masing-masing 5 ekor. Kelompok P1, P2 dan P3 secara berurutan diberikan etanol 15% intra peritoneal dengan dosis 1, 2 dan 3 g/kgbb/hr selama 20 hari. Kinerja memori diukur dengan maze radial 8 lengan dengan parameter Number of Error yaitu angka kesalahan tipe A dibagi jumlah lengan yang dimasuki.Hasil Penelitian : Setelah pemberian etanol selama 20 hari, memori kerja spasial antar kelompok diuji dengan Kruskal Wallis. Hasil tidak ada perbedaan yang bermakna, yaitu 0,070 (p>0,05).Kesimpulan: Tidak ada hubungan yang bermakna memori kerja spasial pada tikus setelah pemberian etanol secara akut.

Analisis Faktor Yang Menghambat Penemuan Suspek Penderita Tuberkulosis di Puskesmas X Prihanti, Gita Sekar; Sari, Nindya Puspita; Pratiwi, Devita Ari; Mabruukah, Laily Putri; Sekarwangi, Dwi Hutami; Firmansyah, Wildan; Cynthiana, Mutiara Vallentin; Masyithoh, Rizdianis Devi
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 2, No 4 (2018): August
Publisher : Universitas Muhammadiyah Semarang

Analysis of Factors in Inhibiting Finding Suspected Tuberculosis Patients at Puskesmas XLatar Belakang: Dalam upaya menurunkan angka kesakitan dan kematian yang diakibatkan penyakit menular seperti tuberculosis, Indonesia menggunakan strategi DOTS untuk skiring dan penemuan kasus TB. Pada tahun 2014 jumlah kasus baru BTA (+) sebanyak 176.677 kasus. Nilai keberhasilan dari kasus TB ditentukan dari nilai penemuan kasus yaitu 70% dari jumlah penduduk. di puskesmas X didapatkan hanya sebesar 43% dari target.Tujuan: menganalisis faktor yang menghambat penemuan suspek penderita tuberkulosis di wilayah kerja puskesmas X Kota Y.Metode: Desain cross sectional dengan melibatkan 250 orang.Hasil: Hasil uji multivariat dengan regresi logistik menunjukkan bahwa terdapat enam variabel yang mempunyai pengaruh signifikan terhadap penemuan kasus suspek TB, yaitu usia > 35 tahun (p=0.000)dengan nilai OR 8,620, gejala awal batuk (p=0.017)dengan nilai OR 3.119, fasilitas kesehatan yang dituju (p=0.000) dengan nilai OR 0.167, stigma rendah (p=0.001)dengan nilai OR 3.005, pengetahuan kurang (p=0.000)dengan nilai OR 8.763, dan status ekonomi rendah (p=0.042)dengan nilai OR 0.427. Berdasarkan nilai Nagelkerke R square yaitu 0,419 (41,9%), menunjukkan bahwa sebesar 41,9% penghambat penemuan kasus suspek TB dijelaskan oleh enam variabel yang berhubungan tersebut, sedangkan 58,1% merupakan faktor penghambat yang dapat dijelaskan oleh variabel lain yang belum diteliti dalam penelitian ini seperti pengaruh kader TB atau pelayanan kesehatan.Simpulan: Faktor yang menghambat penemuan suspek TB yaitu usia > 35 tahun, gejala awal batuk, fasilitas kesehatan yang dituju, stigma rendah, pengetahuan kurang, dan status ekonomi rendah. Background: Indonesia's efforts to reduce morbidity and mortality diseases conduct disease control programs, especially infectious diseases such as tuberculosis with DOTS strategy. In 2014 the number of new cases of smear (+) as many as 176, 677 cases. The success rate of TB cases determined from the discovery of a case that is 70% of the population. in Community Heatlh Center X obtained only 43% of the target. The aim to analysis of the factors that hinder the discovery of suspected tuberculosis in working area Comm unity Health Center of X Kediri City.Methods: cross sectional design studyinvolve of 250 people.Results: The test results of multivariate logistic regression showed that there are six variables that have a significant influence on the discovery of suspected tuberculosis cases, the age> 35 years (p = 0.000) with OR 8.620, the early symptoms of cough (p = 0.017) with OR 3.119, facilities health destination (p =0.000) with OR 0.167, lower stigma (p = 0.001) with OR 3,.05, less knowledge (p = 0.000) with OR 8.763, and the lower economic status (p = 0.042) with OR 0.427. Based Nagelkerke R square value is 0.419 (41.9%), it shows that 41.9% of TB suspect cases inhibitors of the invention described by the six variables related, while 58.1% are factors that can be explained by other variables has not been studied in this research such as TB or influence cadre of health services.Conclusion: Factor inhibiting invention tuberculosis patient suspect are age>35 years, the early symptoms of cough, health care facilities targeted, low stigma, lack of knowledge, and low economic status

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FK UMS Kampus IV UMS Jl. Ahmad Yani, Gonilan, Kartasura, Gonilan, Kec. Kartasura, Kabupaten Sukoharjo, Jawa Tengah 57169. Telepon: (0271) 716844

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Abstract

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Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Muhammad Anas

Contact Email magnamedica21@gmail.com

Phone +62271-716844

Journal Mail Official magnamedica21@gmail.com

Editorial Address FK UMS Kampus IV UMS Jl. Ahmad Yani, Gonilan, Kartasura, Gonilan, Kec. Kartasura, Kabupaten Sukoharjo, Jawa Tengah 57169. Telepon: (0271) 716844

Location Kota semarang, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Muhammad Anas

Contact Email
magnamedica21@gmail.com

Phone
+62271-716844

Journal Mail Official
magnamedica21@gmail.com

Editorial Address
FK UMS Kampus IV UMS Jl. Ahmad Yani, Gonilan, Kartasura, Gonilan, Kec. Kartasura, Kabupaten Sukoharjo, Jawa Tengah 57169. Telepon: (0271) 716844

Location
Kota semarang,

Jawa tengah

INDONESIA