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INDONESIA
Jurnal Respirologi Indonesia
Published by Perhimpunan Dokter Paru Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 364 Documents
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The Accuracy of Lung Ultrasound in Pneumonia Diagnosis: Evidence-Based Case Report Adityo Wibowo; Airin Aldiani; Faiza Hatim; Galoeh Adyasiwi; Hendra Wahyuni MS; Khairunnisa Imaduddin; Malsephira Hasmeryasih; Mega Juliana; Nesia Priandari; Nina Ratu Nur Kharima; Rudy Satriawan; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 41, No 2 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i2.175

Abstract

Background: There are various microorganisms which caused pneumonia in developing countries such as Indonesia. The diagnosjs of pneumonia is still mainly confirmed by Chest X-ray which is unspecific to determine the etiology of pneumonia due to its low accuracy. On the other hand, the higher accuracy diagnostic tool, Computed Tomography (CT) scan, is not cost-effective. Therefore, an alternative diagnostic tool with high precision, affordability, and user-friendly is highly needed. Lung ultrasound (LUS) is an alternative diagnostic device. This study aims to investigate the diagnostic accuracy level of LUS in diagnosing pneumonia. Methods: Literature-researches was done in five databases namely PubMed/MEDLINE, ScienceDirect, Proquest, Cochrane and EBSCO/MEDLINE using keywords according to the clinical scenario. The articles were appraised with CEEBM worksheet. Results: Four articles met the inclusion and exclusion criteria. Sensitivity of LUS ranged around 85-97% and specificity ranged around 8694%. All appraised articles recommended the use of LUS for its high sensitivity in confirming diagnosjs of pneumonia and other lung diseases, and its favorable bedside use especially for critically ill patients. Lung US was also considered as being more inexpensive with less radiation exposure compared to CT scan or other radiographic imaging. Conclusion: Examination using LUS had a high diagnostic value in confirming the diagnosis of pneumonia.
Effect of Inhaled Magnesium Sulphate on Bronchodilating Response, Levels of Substance P and Clinical Improvement of Acute Exacerbations COPD Patients Prima Karita Sari; Suradi Suradi; Jatu Aphridasari
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.135

Abstract

Background: Inhaled magnesium sulphate has a bronchodilator and antiinflammatory effect by block the calcium channels and inhibiting substance P. This study aimed to analyze the effect of magnesium sulfate inhalation on bronchodilator response, substance P levels, and clinical improvement on AECOPD patients. Methods: A quasi-experimental clinical trial, pre-test and post-test design with 34 acute exacerbation of COPD patients who are hospitalized in emergency room on Dr. Moewardi Hospital, Surakarta and Ario Wirawan Hospital, Salatiga on March-April 2017 used consecutive sampling. The independent variable is inhaled magnesium sulphate dose of 150 mg 3 times every 20 minutes when the patients was admitted in emergency room, while the dependent variables are peak expiratory flow rate, the plasma levels of substance P and CAT score acute exacerbation of COPD patients. Results: There was a significant difference (P=0.009) decrease of PEFR value of treatment group (111.76±12.37) compared to control group (141.18±24.21). There was a significant difference (P=0.0001) decrease in CAT score of treatment group (-14.88±1.75) compared to control group (-9.00±1.17). There was a significant difference (P=0.0001) treatment group (-1305.92±417.91) than control group (-355.95±206.25). Conclucions: The addition of MgSO4 inhalation of 150 mg during exacerbation increased PEFR, decreased the level of P substance, and decreased the CAT score with statistically significant results. (J Respir Indo 2018; 38(1): 16-23)
The Effect of Curcumin On Plasma Histamine Level, PEF Variation and Length of Stay of Patients With Acute Exacerbation Asthma Lydia Arista Sutedjo; Suradi Suradi; Ana Rima Setijadi
Jurnal Respirologi Indonesia Vol 38, No 2 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i2.164

Abstract

Introduction: Inflammation in asthma occured in airway especially in submucous layer, and involve eosinophil, neutrophil, lymphocytes T, epitheliat cel, basophil, mast cell, and lymphocytes B. Inflammatory cells produce inflammatory mediators (histamine, leucotrienes, and prostanoid), cytokines, and chemokines that can cause bronchocontriction. This study was conducted to determine and prove the effect of curcumin as adjunctive therapy in acute exacerbation asthma. Curcumin is expected to increase the quality therapy of acute exacerbation asthma. The effect of curcumin is known wiith evaluate plasma histamine level, PEF variation, and length of stay of patient with acute exacerbation asthma. Methods: This study is a quasi experimental study with pretest and posttest design. Sampel of study is 30 patients hospitalizes acute exacerbation asthma in Moewardi hospital and Sohadi Prijonegoro Sragen hospital in August 2016 until september 2016. The subject was taken with concecutive random sampling. Independent variable is curcumin 4x550 mg and dependent variables are plasma histamin level, PEF variation, and length of stay. Result: There is no significant difference (P=0.462) of decreasing plasma histamine level between treatment group 3,988±2,739 ng/ml and control group 3,376±1,606 ng/ml. There is no significant difference (P=0.501) of PEF variation between treatment group 28,126±7,886% and control group 30,400±10,217%. There is no significant difference (P=0.936) of length of stay between treatment group perlakuan 6,333±2,193 days and control group 6,400±2,292 days. Conclusion: Giving curcumin in acute exacerbation asthma while hospitalized didn’t reduce inflammatory marker plasma histamin, PEF variation, and length of stay. (J Respir Indo 2018; 38(2): 100-8)
Differences of Malondialdehyde (MDA) Levels in Blood of Pulmonary Tuberculosis Sufferers with Diabetes Mellitus, Pulmonary Tuberculosis without Diabetes Mellitus and Healthy People in Medan Eka Suhartika; Zainuddin Amir; Bintang Yinke Magdalena Sinaga; Putri C Eyanoer
Jurnal Respirologi Indonesia Vol 40, No 4 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i4.124

Abstract

Background: The imbalance between oxidants and antioxidants in the body can increase Malondialdehyde (MDA) in patients with pulmonary TB and type 2 DM, which causes cell damage and worsens the disease. The body has a protective mechanism from damage caused by increased MDA through enzymatic antioxidants such as SOD and vitamin E. This study aimed to examine the difference in MDA levels in the blood of pulmonary TB patients with type 2 DM, pulmonary tuberculosis without type 2 DM and healthy people in Medan, Indonesia. Methods: This was an analytical study using a case-control approach by measuring MDA levels in pulmonary TB with type 2 DM patients, pulmonary TB patients and healthy people who were treated at H. Adam Malik General Hospital, Community Health Centers, and GP’s practice in Medan for 4 months. Blood samples were taken and examined using the ELISA kit. Data were then analyzed using the Kruskal Wallis and Mann Whitney tests. Results: There were 75 patients recruited in the study in which 45 were males (60%) and 30 were females (40%). The age group found the most was 31-40 years with normal BMI (76%). The highest MDA level was found in the TB+DM group at 12.42 nmol/ml compared to the TB patients (3.75 nmol/ml) and healthy people (3.01 nmol/ml). Conclusion: There were no statistically significant differences in MDA levels although there was a difference found in the MDA levels among the three groups with MDA level in TB+DM group was shown to be the highest.
Case Report Tuberculosis of The Prostate: Findings of Post Transurethral Resection of Prostate (TURP) Procedure Kadek Mien Dwi Cahyani; Ni Made Dwita Yaniswari; Novitasari Novitasari
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.188

Abstract

Background: Prostate tuberculosis (PTB) is one of extra pulmonary tuberculosis which potentially has more frequent fatal complications and more severe quality of life deterioration. It is a very rare disease, with prevalence of 2.6% of all urogenital tuberculosis (UGTB). Prostate tuberculosis may be a sexually transmitted disease and leads to sexual dysfunction. Case: Male, 54 years old, with urinary retention, dysuria, flank pain in the last 1-month, recurrent urinary tract infection in the past 1 year and decrease body weight of 8 kg in 1 month. Physical examination demonstrates enlarged prostate. Patient was referred to Wangaya Hospital with benign prostate hyperplasia (BPH) and suspect malignancy. After underwent clinical and supporting examination, patient underwent TURP procedure. Histopathology examination revealed PTB. Patient was then treated with first line anti-tuberculosis drug (ATD). Discussion: Multiple risk factors are involved in TB disease. PTB spread occur through hematogenous, lymphatic, or direct routes. Clinical features and supporting examinations of PTB are non-specific. Diagnosis often made through incidental histology finding post TURP. Standard ATD regiment administered based on World Health Organization (WHO) guideline. Duration can be prolonged due to suboptimal concentration to prostate tissue. Conclusion: Multidisciplinary approach for extra pulmonary TB is needed. Thorough history taking, and high index of suspicion are important aspects. PTB diagnosis should be considered in patients with recurrent lower urinary tract symptoms refractory to standard therapy in TB endemic area.
Comparison Between The Effect of Clove, Filter and Biomass Cigarette Smoke to The Lung Function of COPD Patients at Harum Melati Pringsewu Clinic Lampung Province, Period January 2013-January 2020 Retno Ariza S Soemarwoto; Hetti Rusmini; Fransisca Sinaga; Agus Dwi Susanto; Arif Widiyantoro
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.153

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a common disease characterized by respiratory symptoms and limited air flow associated with the airways and/or alveolar abnormalities triggered by a significant effect on substances or gases. COPD is the leading of death cause in the world. COPD can be caused by cigarette smoke and biomass. Method: This research is aquantitative method with descriptive analytic and retrospective approach. The samples were 203 COPD patients taken from medical records January 2013-January 2020 at Harum Melati Pringsewu Clinic Lampung Province with statistical test use Analysis Varians (ANOVA) technique. Results: From the characteristics based on type of COPD smoke exposure were clove smokers 127 people (62.6%), filter smokers 3 people (1.5%) and biomass users 73 people (36.0%). The mean lung function COPD patients based on type of smoke exposure were 127 people with clove smokers with average lung function value 55.03%, the lowest value 12.20% and the highest 121.50%. Filter smokers of 3 people with average lung function value 75.07%, the lowest value was 67.00% and the highest 81.41%. Biomass users 73 people with average lung function value 56.91%, the lowest value 19.50% and the highest 149.13%. Comparison the effect clove cigarettes smoke, filter cigarettes and biomass on the pulmonary function of COPD patients obtained P=0.319. Conclusion: There is a decrease lung function in clove smokers, filter smokers and biomass users in COPD patients but not statistically significant difference.
Respiratory Failure in Pneumonia with Diabetic Ketoacidosis (DKA) Novita Maulidiyah; Sri Indah Indriani; Prasenohadi Prasenohadi; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.140

Abstract

The annual incidence rate of KAD is estimated to be between 4.6 and 8 per 1000 patients with diabetes. Based on the results of the physical examination, the patient was diagnosed as pneumonia with KAD. The mortality rate for community pneumonia on outpatients was 2%, inpatients was 5-20%, more so in patients in intensive care that was more than 50%. The problem in the patient is pneumonia. Resulting in pulmonary dysfunction which causes overload. Infections that can increase morbidity and mortality may be associated with Streptococcus infection (group B, S, pneumonia), Legionella and viral infections (influenza). The most common infections are pneumonia and urinary tract infections which account for between 30% and 50% of cases. Therefore, the choice of empiric antimicrobial therapy in diabetic patients with evidence of staphylococcal pneumonia (consistent with sputum smear results or associated soft tissue infection) should be guided by the prevalence of MRSA in the associated institutions. Respiratory failure is a complication of KAD and increases the mortality rate. and morbidity. Based on the high nasal carriage rate, there is an increased risk of staphylococcal pneumonia infection in diabetic patients. Community pneumonia is acute inflammation due to infection of the lung parenchyma acquired in the community. (J Respir Indo 2018; 38(1): 57-63)
Exhaled Carbon Monoxide (eCO) and Serum CC16 Levels in Active Smokers Fitri Indah Sari; Tri Wahju Astuti; Teguh Rahayu Sartono; Garinda Alma Duta
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.181

Abstract

Background: Toxic particles within tobacco smoke are responsible for several respiratory system problems. Among these toxic particles is Carbon Monoxide (CO), produced from environment and Heme Oxygenase induction. Expiratory CO levels can be measured using CO analyzer. CC16 is a pneumoprotein produced by club cells in distal respiratory tract. In acute condition, CC16 level will increase to maintain homeostasis and anti-inflammation. In chronic condition, i.e. in smokers, CC16 will decrease, following destruction of Club cell. This study aims to determine exhaled CO (eCO) levels and serum CC16 levels in active smokers. Methods: This cross-sectional analytical study design has 40 samples of healthy smokers in Brawijaya University who consents to the research from October 2019 until June 2020. The minimum consumption amount is 1 cigarette per day for at least 1 year. eCO levels are measured using CO analyzer (Smokelyzer), while ELISA is used to measure serum CC16 levels. Results: Among 40 subjects, mean eCO level is 10.18 ± 7.42 ppm. Mean serum CC16 level is 3.17 ± 1.78 ng/mL, lower than normal value of 6.4 ng/mL (Lomas et al., 2008). Conclusion: eCO levels increases and serum CC16 level decreases in active smokers, who smokes at least 1 cigarette/day for at least 1 year. This indicates that CO from tobacco smoke could irritate and damage the Club cells in the respiratory system.
Rope Jumping and Tabata Exercise Effect on Lung Function and Physical Fitness Index Stella Tinia Hasianna; Oeij Anindita Adhika; Kartika Dewi; Adra Taufiqah; Ajeng Mira Ayuningsih
Jurnal Respirologi Indonesia Vol 41, No 2 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i2.171

Abstract

Background: Routine physical exercise is often used as an intervention to improve lung function and optimal lung function will improve physical fitness. This study aimed to examine the effect of rope jumping and Tabata exercise in lung function as represented in Forced Expiratory Volume in 1 Second (FEV1), Forced Vital Capacity (FVC) and physical fitness index. Methods: This is an analytic comparative experimental study with pretest and posttest design, involving 60 adult male, separated into 2 groups, which are rope jumping or Tabata exercise for 2 weeks period. The study was conducted at the Faculty of Medicine of Maranatha Christian University Bandung in December 2017 to September 2018. The measured data were FEV1 and FVC using spirometry; and physical fitness index using Harvard Step Test. Data with normal distribution was analyzed using paired T Test, data with abnormal distribution using Mann-Whitney Test, and between group analysis using unpaired T Test. Result: We found a significant increase in FEV1 (P=0.017) but not FVC (P=0.151) in rope jumping grup, and a significant increase in FEV1 (P=0.010) and FVC (P=0.014) in Tabata exercise group. Both physical fitness index in rope jumping group and Tabata exercise group increase significantly (P=0.0005). There are no significant difference between rope jumping and Tabata exercise group in the effect towards FEV1 (P=0.853), FVC (P=0.876) and physical fitness (P=0.545). Conclusion: Rope jumping and Tabata exercise increase lung function and physical fitness index.
Sensitivity Comparison of Pleural Fluid and Serum Neutrophil to Lymphocyte Ratio (NLR) Values in Exudative Pleural Effusion Patients Indra Barata; Zainuddin Amir; Parluhutan Siagian; Putri C Eyanoer; Zulfikar Lubis
Jurnal Respirologi Indonesia Vol 40, No 4 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i4.131

Abstract

Background: Delay in diagnosis and non-compliance to tuberculosis (TB) treatment will increase the risk of MDR TB. WHO recommends GeneXpert as a diagnostic tool, however, the availability is still an obstacle and this tool is not owned by many health facilities. The Neutrophil-Lymphocyte Ratio (NLR) value was thought to be used to estimate the likelihood of TB cases. This study aimed to assess the sensitivity comparison of pleural fluid and serum NLR values in patients with pleural effusion at H. Adam Malik Medan General Hospital. Methods: This was an analytical study with a diagnostic test design, by calculating the sensitivity and specificity of pleural fluid and serum NLR. The sample was calculated by comparing the absolute neutrophil count and the absolute lymphocyte count from both pleural fluid and serum. Results: The sample of this study was 78 patients. In this study, pleural fluid NLR with a cut off value of 2.2 showed a sensitivity of 74% and specificity of 28%, whereas serum NLR with a cut off value of 7.0 produced a sensitivity of 53% and specificity of 68%. Conclusion: The sensitivity of pleural fluid NLR was greater than that of serum, while the specificity of serum NLR was more superior than that of pleural fluid.

Page 12 of 37 | Total Record : 364

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