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INDONESIA
Jurnal Respirologi Indonesia
Published by Perhimpunan Dokter Paru Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 364 Documents
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The Effect of Pulmonary Rehabilitation on The Duration of Antibiotic Switches, IL-10 Levels and PEFR Values in Hospitalized Community Pneumonia Patients Mariyatul Khiptiyah; Iin Noor Chozin; Suryanti Dwi Pratiwi; Rahmad Rahmad; Harun Al Rasyid
Jurnal Respirologi Indonesia Vol 40, No 4 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i4.129

Abstract

Background: Pneumonia is an acute inflammation of the lung parenchyma and ranked third of 30 causes of death in the world. WHO estimates the death caused by pneumonia is 1.6 million per year. Long duration of antibiotic switches is associated with increased morbidity, nosocomial infections and costs of healthcare. This study aims to assess the effect of pulmonary rehabilitation with the duration of antibiotic switches and interleukin-10 (IL-10) levels of pneumonia patients in non-intensive care thus pulmonary rehabilitation can be routinely use as adjuvant therapy. Methods: The study was conducted in May-November 2019 at Saiful Anwar Hospital Malang, with 40 pneumonia patients in the non-intensive care and divided in two groups which contains of 20 patients. This study uses consecutive simple random sampling. In treatment group, pulmonary rehabilitation consists of breathing exercise, effective cough techniques, clapping, postural drainage and breathing muscle exercises with spirometry incentive tools. The pulmonary rehabilitation treatment was done by Medical Rehabilitation Department of Saiful Anwar Malang Hospital. IL-10 levels and PEFR values on the zero and fifth days of treatment were measured. Results: The duration of antibiotic switches received pulmonary rehabilitation was shorter 5.05 days (P
The Association of Working Duration with Lung Function and Chest X-Ray Results in Ceramic Industry Workers of Company X, Mabar Medan Marini Puspita Sari; Amira P Tarigan; Nuryunita Nainggolan; Putri C Eyanoer; Agus Dwi Susanto; Erlangga Samoedro; Caecilia Marliana
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.158

Abstract

Background: Ceramics industry workers are often exposed to silica materials from ceramics. The aim of this study was to determine the association between silica exposure withlung function test and chest x-ray (CXR) results of the workers. Methods: This was an analytical study with cross-sectional design conducted in the Ceramic Industry X in Mabar, Medan City. The dust level in the work station was measured using Personal Dust Sampler. Lung function was measured by spirometry and CXR was evaluated using the ILO interpretations. Results: About 35 male workers were included as subjects, divided into 3 working stations namely precompression section of 11 subjects (31.4%), compression section of 13 subjects (37.1%) and 11 subjects (31.4%) in the sintering section. Dust levels in each work location are 24.8, 29.2, and 6.11 respectively. Of all subjects, 9 (25.7%) had respiratory symptoms, 21 (60%) had restriction in lung function and 8 (22.8%) had abnormal CXR (6 pneumoconiosis and 2 tuberculosis). There were no association between dust levels with lung function and CXR (P>0.05), but there was a significant correlation between duration of work with lung function. The FEV1 and FVC values of subjects working
Risk Factors of Very Severe Pneumonia Incidence in Children Retno Asih Setyoningrum; Hedi Mustiko
Jurnal Respirologi Indonesia Vol 40, No 4 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i4.147

Abstract

Background: Childhood pneumonia is a significant cause of mortality and morbidity in developing countries. About 7-13% of childhood pneumonia present with very severe pneumonia with a high risk of mortality. Identification of risk factors is necessary for early intervention and better management. Methods: Analytic observational study with a cross-sectional approach was conducted with subjects of pneumonia patients aged 2-59 months admitted in Respirology Ward and PICU Department of Pediatrics Dr. Soetomo Surabaya from January 2017 to December 2018. Results: A total of 253 were roled in this study. Group with very severe pneumonia are 140 patients and 113 patients with severe pneumonia. Independent risk factors were analysed by chi-square test and Continuity Correction. Independent risk factors that intluence the incidence of very severe pneumonia in infants and children are patient's age (PR=1.365;P=0.009;95% confidence interval (CI)=1.089-1.712), low birth weight (PR=1.380;P=0.010;95% CI=1.115-1,708), prematurity (PR=1,412;P=0.007;95% CI=1,141-1,747), exclusive breastfeeding (PR=1,434;P=0.007;95% CI=1,093-1,880), nutritional status (PR=2,412;P
Pulmonary Health of Traffic Policemen in Low Air-Polluted Bogor Area Harris Abdullah; Jamal Zaini; Budhi Antariksa; Agus Dwi Susanto; Faisal Yunus
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.183

Abstract

Background: Traffic policemen are very susceptible to respiratory problems due to the potential for exposure to air pollution. Therefore, this study aimed to assess respiratory health aspects of traffic policemen in Bogor, West Java. Method: Registered traffic policemen in Bogor were evaluated for respiratory symptoms, smoking habits, Fagerström Test for Nicotine Dependence (FTND) Questionnaire, chest x-ray, and spirometry. Air quality measurements were also carried out as a reference. Result: During the study period, the air quality in Bogor was classified as “Good” and below the ambient air pollutant standard. A total of 95 traffic policemen participated with a mean age of 37.3±8.7 years (range 23–57 years), mean Body Mass Index (BMI) of 28.1±4.2 kg/m2, and a length of service of 3-38 years (mean of 12.3 years). Mild pulmonary function impairment was found in 7.4% of subjects. About 61% of subjects had a smoking habit but with a low addiction index (FTND) and exCO. Decreased lung function was correlated to BMI and age (P<0.05). Conclusion: Pulmonary function impairment in traffic policemen in Bogor City was correlated to age and BMI.
Effect of Giving Polyphytopharmaca on Improvement in The Degree of Asthma Control through Reduction of Eosinophils and Interleukin-13 Uncontrolled Asthma Patients Aditya Sri Listyoko; Iin Noor Chozin; Susanthy Djajalaksana
Jurnal Respirologi Indonesia Vol 40, No 3 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i3.109

Abstract

Backgrounds: Bronchial asthma is a heterogeneous disease characterized with chronic airway inflammation. The level of asthma control is an indicator of asthma management outcomes. It is influenced by a complex immunological mechanism, included the role of IL-13 as a key biomarker of inflammation. We investigate the effect of Poly-Phytopharm (Kleinhovia hospita 100 mg, Curcuma xanthorriza 75 mg, Nigella sativa 100 mg and Ophiocephalus striatus 100 mg) on the level of asthma control tests (ACT) score, blood eosinophils, and serum IL-13 on not fully controlled asthma stable patients. Methods: This study used quasi-experimental pre and post test methods, in 15 stable asthma patients who were not fully controlled at the pulmonary outpatient clinic of Dr. Saiful Anwar General Hospital, Malang. Assessment of ACT score, blood eosinophils, and serum IL-13 are carried out before and after supplementation of Poly-Phytopharm three times a day, two capsules respectively for 12 weeks. The ACT was scored by the investigator by direct questioning of patients, the blood eosinophil was measured with blood analysis, and the IL-13 in serum was detected with qPCR method. Results: There is significant increase of ACT score (18.07±2.57 to 22.06±1.83; P=0.001). In subject with baseline eosinophils ≥300 pg/mL (n=9), there were significant reduction in blood eosinophils (653.15±276.77/µL to 460.66±202.04/µL; P=0.038), and a decrease of serum IL-13 (17.69±9.901 pg/ml to 16.17±12.438 pg/ml; P=0.609). Conclusions: The administration of poly-phytopharm for 12 weeks improves ACT level, decreases blood eosinophils, and decrease serum IL-13 on not fully controlled asthma stable patients. (J Respir Indo. 2020; 40(3): 130-8)
High Sensitive C-Reactive Protein as a Marker of Systemic Inflammation in Male Coronary Artery Disease with Obstructive Sleep Apnea Allen Widysanto; Audrey Suryani Soetjipto; Michelle Widysanto
Jurnal Respirologi Indonesia Vol 41, No 2 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i2.176

Abstract

Background: High Sensitive C-Reactive Protein (hsCRP) is an acute phase protein which may be used as a sensitive marker for increased risk of cardiovascular events in Obstructive Sleep Apnea (OSA) subjects. Methods: This was a cross-sectional study to evaluate hsCRP as a sensitive marker for cardiovascular events in Obstructive Sleep Apnea (OSA) subjects. Subjects were recruited at Medical Check-up Department, Siloam Hospital Lippo Village, Karawaci, Tangerang between January and December 2018. This study included 74 OSA men whose blood were collected after fasting prior to hsCRP test. The diagnosis of Coronary Artery Disease (CAD) was determined by previous medical examinations using treadmill test, CT angiography and cardiac catheterization. Results: There were 39 people (52,7%) who were diagnosed with CAD out of 74 OSA men. The cut off point for hsCRP more than 0,42 was a marker for increased risk for CAD with Odds Ratio (OR)=7,43, Relative Risk (RR)=88%, sensitivity=17,95%, specificity=97,14%, Likelihood ratio (LR+) 6,28 and LR(-) 0,84. Conclusion: HsCRP with cut-off point >0,42 could be used as a marker of increased risk of cardiovascular case in male OSA subjects.
Effects of Green Tea to Absolute Neutrophil Count, MMP-9, %VEP1, and COPD Assessment Test Scores Stable COPD Patients Hendrastutik Apriningsih; Suradi Suradi; Yusup Subagio Sutanto
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.134

Abstract

Backgrounds: Chronic obstructive pulmonary disease is the leading cause morbidity and mortality worldwide. Cigarette smoke and noxious agent causing oxidative stress activated nuclear factor-κB then increase inflammatory genes releases. Epigallocatechin-3-gallate green tea have antiiinflammatory effect which can be use as addition therapy for stable COPD. Methods: This study aimed to analyze the effect of EGCG to absolute neutrophil count (ANC), serum MMP-9, %FEV1, and CAT score stable COPD patients. Clinical trials of experimental with pre-test and post-test design was conducted on 30 patients in Dr. Moewardi Hospital Surakarta from February-April 2017. Samples were taken by consecutive sampling divided into treatment group (n=15) received standard therapy and green tea capsule 2x500mg/day during 28 days and control group received only standard therapy (n=15). Decreased inflammation measured by ANC and serum MMP-9, improvement of obstruction measured by %FEV1, and clinic improvement measured by CAT score. Results: There were no significant differences (P=0.135) decrease ANC treatment group (-662.45±1446.80 µL) compared control (413.79±2292.90 µL), decrease serum MMP-9 (P=0.413) treatment group (-324.34±333.56 ng/ml) compared control (-181.21±577.52 ng/ml), %FEV1 (P=0.236) treatment group (2.56±10.77), compared control (-4.30±19.12), and significant difference (P=0.034) CAT score treatment group (-1.07±1.16) compared control (-0.20±1.08). Conclusions: The addition of green tea capsule 2x500 mg/day during 28 days was significantly lowered CAT score, decreasing ANC, serum MMP-9 and increasing %FEV1 but not significant. (J Respir Indo 2018; 38(1): 7-15)
The Relationship between Tyr113His Epoxidized Hydrolase Enzyme Gene Polymorphisms and the Incidence of Smoking Lung Cancer Lucia Aktalina; Amira Permatasari Tarigan; Noni Novisari Soeroso; Yahwardiah Siregar; Ozar Sanuddin
Jurnal Respirologi Indonesia Vol 38, No 2 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i2.163

Abstract

Background: This study aims to determine the relationship between the gene polymorphism of the enzyme Epoxid Hydrolase (EPHX) Tyr113His and the tendency of smokers to suffer from lung cancer. The EPHX Tyr113His gene polymorphism is a change in one nucleotide base of the EPHX gene to produce enzymes with decreased function by 50%. EPHX plays a role in the metabolism of chemical compounds in cigarette smoke, especially Benzo (a) Pyren (BaP), which becomes a carcinogen in the body. Methods: This study is a case-control study design conducted from October 2016 to February 2017. Venous blood was taken from 35 people with lung cancer at RSUP H Adam Malik Medan and 35 healthy smokers. The genotype examination of the EPHX gene was carried out using the PCR-RFLP method in the USU FK Integrated Laboratory. Results: The genotype frequency of heterozygous variant T/C and homozygous variant C/C in case groups was 83.3% and 16.7%, respectively. The frequency of the T allele in the case group was 41.67% and the C allele was 58.33%. Whereas in the control, the frequency was heterozygous variant T/C (80%) and homozygous variant C/C (20%). The frequency of the T allele in the control group was 40% and the C allele was 60%. There were no homozygous wildtype T/T genotypes in the two groups. There was no significant difference in the genetic distribution and allele distribution of the EPHX enzyme between case and control groups. Conclusion: There is no relationship between EPHX Tyr113His enzyme gene polymorphisms and the incidence of lung cancer in smoking. J Respir Indo 2018; 38(2): 93-9)
Correlation of qSOFA and NLR to Procalcitonin Levels for Predicting Outcome of Pneumonia Sepsis Patients at RSUP dr. M. Djamil Padang Ibnu Arief Dafitri; Oea Khairsyaf; Irvan Medison; Yessy S. Sabri
Jurnal Respirologi Indonesia Vol 40, No 3 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Backgrounds: Sepsis is a common complication that occurs due to infection and can increase morbidity and mortality in patients. Several methods are applied to evaluate the prognosis of sepsis, such as quick Sequential Organ Failure Assesment (qSOFA) score, Neutrophil Lymphocyte Ratio (NLR) and procalcitonin. This study aimed to determine correlation of qSOFA and NLR on procalcitonin levels to predict the outcome of pneumonia sepsis patients in the pulmonary ward of RSUP dr. M. Djamil Padang. Methods: This was a cross sectional study of pneumonia sepsis patients in the pulmonary ward of the RSUP dr. M. Djamil Padang during September 2019 - February 2020. The qSOFA score was assessed based on physical examination, while both NLR and procalcitonin were measured from blood tests. Results: There was a significant relationship between qSOFA score and procalcitonin levels (r=0.409; P=0.006). There were no significant correlation between NLR and procalcitonin levels (r=0.232; P=0.134). There was a significant correlation between qSOFA score and patient outcome (P=0.036), there was no significant relationships between procalcitonin levels and patient outcomes (P=0.249), and there were no significant correlation between NLR and patient outcomes (P=0.157). Conclusions: qSOFA score was more considered method to evaluate the outcome of pneumonia sepsis patients. (J Respir Indo. 2020; 40(3): 173-81)
Risk Factors Affecting Respiratory Symptoms and Impaired Lung Function of Palm Oil Mill Workers in the District of Kandis Surya Hajar Fitria Dana; Indi Esha; Faisal Yunus; Adrianison Adrianison; Azizman Saad; Ridha Restilla
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.194

Abstract

Background: Air pollution that exposed to human have been a problem all over the world and caused a variety of lung disease. Gases and particles emitted from industry including sulfur oxide, nitrogen oxide, and particulate matter may lead to decreasing lung function. Sulfur dioxide is one of the highest causes of air pollution at the highest level. Workers exposure to gases were vulnerable to respiratory function abnormality. Methods: A study on the effect of risk factors and sulfur dioxide exposure on lung function of palm oil workers in the district of Kandis was carried out in December 2019–January 2020. The research aim at describing sulfur dioxide air ambient in palm oil mill as well as respiratory state of palm oil workers and analyzing sulfur dioxide exposure and lung function relationship. Result: The result showed that sulfur dioxide concentration in outdoor 25.7 µg/Nm3 and indoor 20.6 µg/Nm3. The result of spirometry showed obstruction in 13% of the workers. Breathlessness and productive cough are the most common symptoms. Several factors that correlated with lung function namely as personal protective equipment (p=0.001), length of working (p=0.003), and smoking habit (p=0.004). From multivariate analysis, personal protective equipment has a significant correlation with lung function (p=0.038). Conclusion: Increasing the concentration of sulfur dioxide may cause decreased of lung function but other factor like personal protective equipment showed a significant correlation with lung function.

Page 10 of 37 | Total Record : 364

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