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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
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Prevalence, characteristics and risk factors of suicides in Denpasar from 2014-2016 Pravinthiran Manokaran; Luh Nyoman Alit Aryani; Ni Ketut Putri Ariani
Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (814.847 KB) | DOI: 10.15562/ism.v9i2.159

Abstract

Suicide is an important health issue worldwide which is generally on the rise from annually. It has no known pathophysiology; it interlinks psychological, biological, societal and environmental factors. Aim: This study was conducted to identify the prevalence and various variables, such as characteristics, methods and risk factors of attempted and completed suicides. Methods: This is a cross-sectional descriptive study which was conducted in Denpasar from 2014-2016 and the subjects of study are those attempted and died from suicides. Data were collected from resident’s log book and medical records from Psychiatric and Forensic departments in RSUP Sanglah and police reports from Polresta Denpasar. Data collected from Polresta has also included those from Forensic. Results: Age group 15-29 years (121), females (118), married people (82), private sector employees (109), and Balinese (108) have highest numbers of suicide attempts in their respective character groups. Poisoning (145) and problems with a partner (99) are the most typical methods of choice and risk factor respectively among the 176 cases of attempted suicides. Age group 30-49 years (11), males (17), married people (16), private sector employees (16), and Balinese (13) have highest numbers of completed suicides. Hanging (22) and economy crisis (13) are the most prevalent method and risk factor among the 23 cases of completed suicides. Conclusion: Findings of this study show that there were 176 suicide attempts and 23 suicide deaths in Denpasar from 2014-2016.
The relationship between the decrease in Glomerulus Filtration Rate (GFR) and the increase in amount of coronary artery lesions on coronary heart disease patients in Sanglah General Hospital, Denpasar-Indonesia I Nyoman Triaditya Kresna Putra; I Kadek Susila Dharma; Ida Bagus Rangga Wibhuti
Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.389 KB) | DOI: 10.15562/ism.v9i2.160

Abstract

Coronary heart disease or coronary artery disease is caused by the atherosclerosis process in the coronary blood vessels. The high number of patients with this condition is significantly due to the influence of modern and all instant lifestyle. Among the factors suspected to be capable of influencing the increase in the number of coronary artery lesions in coronary heart patients is the Glomerulus Filtration Rate (GFR). This result is related to the high mortality and morbidity of coronary heart patients. Aim: The purpose of this research is to determine the relationship between the decrease in glomerulus filtration rate (GFR), the disturbance variables (age, gender, hypertension history, diabetes mellitus history, smoking history) and the increase in the number of coronary artery lesions in Sanglah General Hospital. Methods: This research is an analytical observational design with the cross-sectional design using secondary data from the medical records in Sanglah General Hospital Denpasar. This study attains 196 sample. Results: A significant relationship is attained between GFR (<60 ml/ minute) and the increase in the total vessel score (p = 0.017) with an OR 2.47 (CI95% 1.014-6.041). Furthermore, there is a significant relationship between risky age (male >45, female >55) and the increase in total vessel score (p = 0.015) with an OR 3.54 (CI 95% 1.217-10.307). Diabetes mellitus and the increase in the total vessel score also shows a significant relationship  (p = 0.016) with an OR 2.99 (CI 95% 1.189-7.539). While other risk factors such as gender, hypertension, and smoking have an insignificant relationship (p > 0.05). In the multivariate analysis, GFR (<60 ml/ minute) is a predictor of the vessel score (p=0,050) with an adjusted value of OR 1.86 (CI 95% 0.735-4.725). There are some other variables in which are significant predictors of the increase in vessel score. Risky age (male >45, female >55) (p=0,048) with an adjusted OR value of 3.08 (CI 95% 1.012- 9.407) and also diabetes mellitus (p=0.044) with an adjusted OR value of 2.65 (CI 95% 0.145-0.973) are those predictors. Conclusion: Hence, it appears that GFR (<60 ml/ minute), risky age (male >45, female >55) and diabetes mellitus have a significant relationship with the increase in vessel score and are predictors of the increase in vessel score. While gender, hypertension, and smoking do not have significant relationships with the increase in the amount of vessel score.
Risk factors of preeclampsia and eclampsia in Sanglah General Hospital from March 2016 to March 2017 Ng Teng Fung Vincent; I Made Darmayasa; Anom Suardika
Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.343 KB) | DOI: 10.15562/ism.v9i2.162

Abstract

Background: Preeclampsia and eclampsia have been increasing at an alarming rate. It is a challenging task for doctors and pregnant mothers. Preeclampsia defined as new onset of hypertension (≥140mmHg systolic or ≥90mm Hg diastolic on at least two occasions 6 hours apart) and proteinuria (at least 1+ on dipstick or ≥300mg in a 24-hour urine collection) after 20 weeks of gestation. Eclampsia defined as neurologic involvement in the form of generalized tonic-clonic convulsions in women with preeclampsia is termed eclampsia if the seizures cannot be attributed to any other cause such as epilepsy, cerebral infection, tumor or ruptured aneurysm. Aim: This study aims to find the association of risk factors for preeclampsia and eclampsia. The risk factors for preeclampsia and eclampsia are obesity, primigravida, multiple pregnancies, diabetes, pre-existing hypertension, family history, expecting mother’s age, nutritional status, and socioeconomic status. The study was carried out by using descriptive research and data were collected from medical records in Sanglah hospital which has 140 cases. Results: The results for preeclampsia are highest in expecting the age of 20-35 years old, primigravida women with gestational age > 37 weeks, overweight and overnourished women, a middle socioeconomic status and also without risk factors. The results for eclampsia are dominant in expecting age of 20-35 years old, primigravida women with gestational age > 37 weeks, women with middle socioeconomic status and majority without risk factors, and women who are overweight and overnourished. Conclusion: Preeclampsia and eclampsia cases are highest in expecting age of 20-35 years old, primigravida women with gestational age >37 weeks, overweight and overnourished women, majority women without risk factors and from middle socioeconomic status.
Karakteristik kanker payudara usia muda di Subbagian Bedah Onkologi Rumah Sakit Umum Pusat Sanglah tahun 2014-2016 Putu Diahpradnya Oka Partini; I Wayan Niryana; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 9 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.631 KB) | DOI: 10.15562/ism.v9i1.163

Abstract

Latar Belakang: Kanker payudara merupakan jenis kanker yang paling sering terjadi pada wanita. Kasus kanker payudara pada usia muda (dibawah 40 tahun) cenderung memiliki presentase yang lebih rendah diantara usia tua, namun memiliki prognosis yang lebih buruk. Penelitian ini dilakukan untuk mengetahui karakteristik kanker payudara usia muda di Sub Bagian Bedah Onkologi Rumah Sakit Umum Pusat Sanglah tahun 2014-2016 berdasarkan stadium, subtipe, dan jenis histopatologi.Metode: Penelitian ini merupakan penelitian deskriptif dengan desain cross sectional, yang datanya diperoleh dari data register pasien kanker payudara di RSUP Sanglah dan diolah menggunakan aplikasi SPSS.Hasil: Hasil penelitian menunjukkan, jumlah pasien kanker payudara usia muda (<40 tahun) adalah sekitar 72 orang (14%) dari total 514 pasien kanker payudara. Rentang usia muda terbanyak adalah pada rentang usia 35-39 tahun yaitu sekitar 34 orang (47.2%). Stadium kanker payudara usia muda terbanyak adalah stadium IIIB dan IV masing-masing sebesar 19 orang (26.4%). Jenis histopatologi kanker payudara usia muda terbanyak adalah karsinoma duktal invasif sebesar 61 orang (84.7%). Subtipe kanker payudara usia muda terbanyak adalah Luminal B sebesar 31 orang (43.1%).Simpulan: Karakteristik Kanker Payudara Usia Muda di Subbagian Bedah Onkologi Rumah Sakit Umum Pusat Sanglah cenderung mirip dengan penelitian-penelitian yang pernah dilakukan sebelumnya, meskipun beberapa variabel yang menunjukkan angka persentase yang berbeda dengan penelitian-penelitian sebelumnya.
Hubungan status kesehatan berdasarkan WOMAC dengan kualitas hidup berdasarkan WHOQOL-BREF pada pasien osteoartritis lutut di Rumah Sakit Sanglah tahun 2016-2017 Ni Putu Ayu Pande Arista Dewi; Wayan Subawa; Agung Artha Wiguna
Intisari Sains Medis Vol. 9 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (222.413 KB) | DOI: 10.15562/ism.v9i1.164

Abstract

Latar Belakang: Osteoartritis (OA) merupakan penyakit degeneratif pada persendian yang bersifat kronik. Keterbatasan fungsi yang dialami oleh penderita osteoartritis lutut berhubungan dengan adanya perubahan pada kualitas hidup. Kualitas hidup tidak hanya dipengaruhi oleh keadaan fisik dari penderita OA, namun juga dipengaruhi oleh mental dan psikis. Hal ini juga penting digunakan sebagai terapi secara menyeluruh bagi penderita OA, tidak hanya dalam bidang klinis, akan tetapi bidang mental dan psikis penderita juga harus diperhatikan dan menjadi tolok ukur dalam keberhasilan suatu terapiMetode: Penelitian ini merupakan penelitian analitik dengan pendekatan cross-sectional mencari hubungan antara variabel bebas (status kesehatan) dengan variabel tergantung (kualitas hidup). Sampel penelitian adalah pasien OA lutut yang telah terdiagnosis secara klinis dan radiografi di RSUP Sanglah pada tahun 2016-2017. Penelitian dilaksanakan dengan memberikan 2 kuesioner ke rumah masing-masing subjek.Hasil: Dari 38 responden 26,3% merupakan laki-laki dan 73,7% merupakan perempuan. Hasil penelitian ini menunjukan bahwa: (1)Terdapat hubungan positif yang signifikan (r=0,345, p=0,034) antara status kesehatan dengan kualitas hidup, (2) perbedaan hubungan rerata diantara masing-masing domain, dimana terdapat hubungan negatif yang signifikan (r= -0,324, p= 0,048) antara status kesehatan dengan domain kesehatan fisik pada WHOQOL-BREF dan hubungan yang positif signifikan antara status kesehatan dengan domain psikologis (r=0,328, p=0,044), hubungan sosial (r=0,325, p=0,047) lingkungan (r=0,530, p=0,001) pada WHOQOL-BREF.Simpulan: Terdapat hubungan yang positif signifikan antara status kesehatan berdasarkan rerata skor WOMAC dengan kualitas hidup berdasarkan WHOQOL-BREF pada pasien OA lutut di RS Sanglah tahun 2016-2017. Hasil penelitian ini diharapkan dengan meningkatkan kualitas hidup dapat membantu terapi pasien OA lutut agar tercapai hasil terapi yang maksimal. 
Gambaran stadium dan jenis histopatologi kanker payudara di Subbagian Bedah Onkologi RSUP Sanglah Denpasar tahun 2015-2016 I Gde Made Satya Wangsa Satya Wangsa; I Wayan Niryana; Putu Anda Tusta Adiputra Anda Tusta Adiputra; Ni Putu Ayu Pande Arista Dewi
Intisari Sains Medis Vol. 9 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.336 KB) | DOI: 10.15562/ism.v9i1.165

Abstract

Latar Belakang: Kanker payudara merupakan suatu penyakit neoplasma yang ganas dimana pada jaringan parekim terdapat pertumbuhan jaringan payudara abnormal yang bersifat infiltratif dan desktruktif serta dapat bermetastase. Tingginya kasus kanker payudara di Indonesia, tidak selalu diikuti oleh penentuan stadium klinis dan histopatologi secara lengkap, padahal penentuan stadium klinis dan histopatologi diperlukan untuk menentukan diagnosis dan tata laksana lebih lanjut. Pengetahuan mengenai gambaran stadium dan jenis histopatologi juga menjadi salah satu indikator penting dalam penentuan prognosis kanker payudara.Metode: Penelitian ini merupakan penelitian deskriptif dengan pendekatan potong lintang (cross-sectional), yang datanya didapatkan dari data rekam medis di RSUP Sanglah dengan subjek penelitian pasien yang terdiagnosis kanker payudara pada tahun 2015-2016 kemudian diolah dan dianalisis dengan bantuan software SPSS.Hasil: Berdasarkan stadium, pasien kanker payudara dengan stadium EBC (Early Breast Cancer) sebanyak 30,08% dengan 2,95% pasien stadium I, 13,39% stadium IIA, 13,73% stadium IIB. Pasien terdiagnosis dengan stadium LABC (Locally Advance Breast Cancer) berjumlah 273 (47,47%) pasien dengan secara berturut-turut 14,78%, 30,95% dan 1,73% pasien stadium IIIA, IIIB dan IIIC. Pada penelitian ini juga tercatat sebanyak 129 (22,43%) pasien dengan kanker payudara yang sudah metastasis (stadium IV). Berdasarkan histopatologi, sebanyak 483 (84%) pasien dengan karsinoma duktal invasif, 61(10,60%) pasien dengan karsinoma lobular invasif, dan 31 (5,40%) pasien dengan karsinoma tipe lain.Simpulan: Hasil penelitian ini didapatkan bahwa pasien yang terdiagnosis kanker payudara di RSUP Sanglah pada tahun 2015-2016 sebanyak 575 pasien dengan stadium kanker payudara terbanyak adalah Locally Advance Breast Cancer (LABC) (Stadium IIIA, IIIB, IIIC) dengan jumlah 273 (47,47%) pasien. Jenis histopatologi kanker payudara terbanyak adalah karsinoma duktal invasif dengan jumlah 483 (84%) pasien.
Pemberian antibiotik cefotaxime dengan konsentrasi sublethal pada isolat Klebsiella pnuemoniae yang resisten terhadap ampicilin menginduksi Multi Drug Resisten (MDR) Gema Zakharian; Dewa Made Sukrama; Ni Nengah Dwi Fatmawati
Intisari Sains Medis Vol. 9 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1190.345 KB) | DOI: 10.15562/ism.v9i1.166

Abstract

Background: Antibiotic resistance causes frequent infections to be difficult to treat and may aggravate the condition of infected patients which are requiring longer and more expensive antibiotic therapy. Klebsiella sp. is the most potential germ that causes nosocomial infections in the hospital. Klebsiella sp. which resulted a positive ESBL being perceived to directly exacerbate public health problems and become the center of attention in some countries, including Europe and America. Methods: This study used 32 repetitions with Klebsiella pneumoniae isolate obtained from Clinical Microbiology Installation of Sanglah General Hospital. Isolate was divided into two groups, the first group was not given the treatment of cefotaxime with sublethal concentration and the second group was given the treatment of cefotaxime with sublethal concentration. Resutls: The results of the treatment were tested by Pearson Chi Square method with the result that cefotaxime treatment with sublethal concentration significantly caused resistance to Klebsiella pneumoniae isolate and was proved by p value of 0.014 (p <0.05). Conclusions: Antibiotic test results using Vitex found isolates Klebsiella pneumoniae are resistant to more than two antibiotics and isolates are also germs that have Extended Spectrum Beta-Lactamase (ESBL).
Hubungan antara bayi berat lahir rendah dengan asfiksia neonatarum di RSUD Wangaya Kota Denpasar Ida Bagus Wiadnyana; I Wayan Bikin Suryawan; A.A Made Sucipta
Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.28 KB) | DOI: 10.15562/ism.v9i2.167

Abstract

Latar Belakang: Bayi Berat Lahir Rendah (BBLR) pada bayi masih merupakan masalah di bidang kesehatan terutama kesehatan perinatal. Prevalensi bayi dengan berat badan lahir rendah (BBLR) diperkirakan 15% dari seluruh kelahiran di dunia dengan batasan 3,3%-38% dan lebih sering terjadi di negara berkembang atau negara dengan sosio-ekonomi rendah. Komplikasi yang sering terjadi pada BBLR seperti hipotermi, gangguan pernafasan, gangguan alat pencernaan, gangguan immunologi, immatur hati, immatur ginjal serta perdarahan. Pada BBLR dapat terjadi kekurangan surfaktan dan belum sempurna pertumbuhan dan perkembangan paru sehingga kesulitan memulai pernafasan yang berakibat untuk terjadi asfiksia neonatorum. Tujuan dari penelitian ini adalah untuk mengetahui hubungan derajat BBLR dengan derajat asfiksia neonatorum.Metode: Jenis penelitian yang digunakan adalah observasional analitik dengan rancangan penelitian cross sectional. Pada penelitian ini, pengambilan sampel dilakukan pada BBLR di RSUD Wangaya periode April 2016 - April 2017 di ruang Nicu dan Perinatologi sampai jumlah sampel penelitian yang memenuhi kriteria inklusi dan eksklusi dengan jumlah sample total 87 sampel. Sampel diperoleh melalui metode consecutive sampling, selanjutnya dilakukan pengumpulan data yang diperlukan. Data yang diperoleh dianalisis secara analitik, selanjutnya disajikan dalam tabulasi data serta dijabarkan menggunakan tabel dan narasi.Hasil: Terdapat hubungan yang signifikan antara derajat BBLR dengan derajat Asfiksia Neonatarum (p=0,03), BBLR merupakan factor resiko terhadap derajat asfiksia dengan nilai resiko prevalensi (RP)=2,08 (IK 95%=1,08 – 1,30).Simpulan: Terdapat hubungan yang signifikan antara derajat BBLR dengan derajat Asfiksia Neonatarum.
Gambaran pengetahuan, sikap, dan praktik ibu balita terhadap penatalaksanaan diare pada anak balita di wilayah kerja Puskesmas Abang 1 Made Rahayu Suryapramita Dusak; Yetty Sukmayani; Stephanie Apriliana Hardika; Luh Putu Ariastuti
Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.358 KB) | DOI: 10.15562/ism.v9i2.168

Abstract

Latar Belakang: Diare merupakan salah satu permasalahan kesehatan dunia yang menjadi penyebab utama kedua kematian anak dibawah lima tahun. Diare dan gastroenteritis dengan penyebab infeksi juga ditemukan masih termasuk ke dalam 10 besar penyakit dengan kunjungan terbanyak di Puskesmas Abang I, Karangasem. Edukasi kesehatan mengenai diare pada balita serta penanganannya penting untuk keefektifan penatalaksanaan kasus diare. Berdasarkan survei singkat yang dilakukan pada 10 orang ibu balita terkait dengan penanganan diare di rumah didapatkan bahwa sebagian besar (70%) ibu balita memberikan penanganan yang kurang tepat. Hal ini menunjukkan kecenderungan perilaku yang kurang tepat dalam penatalaksanaan diare di rumah.Metode:  Penelitian ini merupakan studi deskriptif cross sectional dengan melibatkan 62 subjek penelitian yang merupakan ibu balita di wilayah kerja Puskesmas Abang I. Penelitian ini dilakukan bertujuan untuk mengetahui gambaran pengetahuan, sikap, dan praktik ibu balita dalam penatalaksanaan diare pada anak balita di wilayah kerja Puskesmas Abang I. Penelitian ini menggunakan metode purposive sampling untuk memilih tiga desa yang berada di wilayah kerja Puskesmas Abang I dan pengambilan sampel dilakukan dengan snowballing method. Cara pengumpulan data pada penelitian ini dengan melakukan wawancara berbasis kuesioner.Hasil: Pada penelitian ini didapatkan gambaran pengetahuan mengenai diare pada balita mayoritas dalam kategori kurang (91,9%).Simpulan: ibu balita memiliki pengetahuan kurang terkait penatalaksanaan diare pada balita, dimana sebagian besar ibu balita masih merespon negatif dalam penanganan awal saat anak mengalami buang air besar lebih encer dari biasanya serta penanganan diare cukup dengan oralit saja. Selain itu, sebagian besar ibu balita juga masih memiliki praktik yang kurang tepat terkait penggunaan obat tradisional dan pemberian teh manis pada balita dengan diare.
Prevalence of colorectal carcinoma based on microscopic type, sex, age and anatomical location in Sanglah General Hospital Michelle Anne Anthonysamy; Luh Putu lin Indrayani Maker; I Made Gotra; Herman Saputra
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.753 KB) | DOI: 10.15562/ism.v10i2.171

Abstract

Background: Colorectal carcinoma (CRC) is a disease in which epithelial cells in the colon or rectum become abnormal and divide without control, forming a mass called a tumor. Colorectal carcinoma is the fourth most frequent cancer in men after prostate and lung or bronchus cancers whereas in women is the third most frequent cancer after breast and lung or bronchus cancers. Colorectal cancer is a leading cause of cancer death worldwide, accounting for 693,900 deaths in 2012 and is the fourth most frequent cancer in men whereas in women is the third most frequent cancer. In Indonesia amount of rectal cancer were 1407 (5.67%) and 990 cases (3.99%) of colon cancer. Specifically in Denpasar, there are a total of 75 cases (7.11%) of rectal cancer and 38 cases (3.60%) of colon cancer in the year.Aim: This study aims to know the prevalence of colorectal carcinoma based on microscopic type, sex, age and anatomical location in Sanglah General Hospital in Denpasar from January 2014 to January 2016.Method: This study used descriptive retrospective research based on the secondary data from patients medical record which was taken at Sanglah General Hospital from January 2014 to January 2016. Population and sample amounted to 275 patients.Results: This study shows that the highest prevalence of colorectal carcinoma was in a group of age <50 years old with 86 samples (31.3%) and in a male with 163 samples (59.3%). Adenocarcinoma has the highest prevalence of colorectal carcinoma with 270 samples (98.2%). The rectum was the most frequent tumor location with 170 samples (61.8%). In adenocarcinoma, the age group with the highest prevalence of CRC was <50 years with 85 samples (30.9%). The highest prevalence of CRC based on anatomical location and age group was <50 years in the rectum with 57 samples (20.7%).Conclusion: Most of the CRC was found in age group < 50 years, men had a higher risk to get colorectal carcinoma, adenocarcinoma is the most common microscopic type, and rectum was the most common site of colorectal carcinoma.

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