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Jurnal Farmasi Higea

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Published by Sekolah Tinggi Ilmu Farmasi Padang

ISSN : - EISSN : 25413554 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Arjuna Subject : -

Articles 347 Documents

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Pembuatan Emulsi Virgin Coconut Oil (VCO) Dengan Pulvis Gummi Arabici (PGA) Dan Uji Aktivitasnya Terhadap SGOT Dan SGPT pada Mencit Putih Nori Wirahmi; Sonia Yuwana; Salman Umar
Jurnal Farmasi Higea Vol 1, No 1 (2009)
Publisher : STIFARM Padang

The research of the making of Virgin Coconut Oil emulsion with the Acasia and its activity test as a SGOT dan SGPT against white female mouse had been done. The liver damage was inducted using paracetamol doses 0.026 g/20g BB. The emulsion was made with dry gom method and evaluated in stability and VCO emulsion viscocity using a Viscometer Stomer. The parameter observed was the decreasing of SGOT and SGPT activities during giving 1, 3, 7 medicine. The result indicated that the emulsion VCO was stable using Acasia as emulsifying agent to 50°C during 6 hours and can be used as the decreasing SGOT and SGPT activities at observating on day 2, 4 and 8.

Pengaruh Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Terhadap pH dan Tukak Lambung Pada Tikus Putih Jantan Sri Oktavia; Helmi Arifin; Ria Irawati
Jurnal Farmasi Higea Vol 7, No 2 (2015)
Publisher : STIFARM Padang

The effect of basil (Ocimum sanctum L.) leaf ethanolic extract on pH and gastric ulcers in male rats induced by ethanolic absolute 1 mL /200 g BW orally has been evaluated. The observed parameters where pH change gastric liquid and ulcer index value. The result indicated that the basil (Ocimum sanctum L.) leaf ethanolic extract at doses of 100 mg/KgBW. 300 mg/KgBW and 900 mg/KgBW significantly decreased the ulcer index with curative ratio where 45.82 %, 62.94 % and 80.65 % (for one time given extracts for two days), 49.13 %, 77.69 % and 94.62 % (for one time given extract for four days) 52.71 %, 77.67 % and 97.21 % (for one time given extract for six days) compared to the positive control. The extracts at 100 mg/KgBW, 300 mg/KgBW and 900 mg/KgBW also significantly decreased the gastric acid pH to its normal value (P<0.05).

Pembuatan Kalsium Glukonat Dari Batu Kapur Bukit Tui Padang Panjang Zulharmita Zulharmita; Sri Indah Kesuma; Fithriani Armin
Jurnal Farmasi Higea Vol 6, No 1 (2014)
Publisher : STIFARM Padang

A study concerning the manufacture of calcium gluconate limestone hill Tui Leopold. Previous limestone samples were identified and determined the levels of calcium. 1 g sample of limestone calcium levels obtained 36,0812 %. In the manufacture of calcium gluconate used limestone samples of 20 g were dissolved in 6 M HCl, filtered and the filtrate was added 6 M NH4OH to pH 10 . Then added gluconic acid 1 M. The precipitate is filtered, washed, dried in an oven at a temperature of 1050 C. The results obtained as 6,2084 g of calcium gluconate. Examination of limestone calcium gluconate include organoleptic examination, solubility, qualitative identification, examination and the melting point of the assay by the method complexometry. In the assay of calcium gluconate from the manufacture of natural limestone samples carefully weighed approximately 0,5 g , 1 g, and 2 g. Of the three differences in weight percentage of calcium gluconate calcium results obtained, weighing 0,5 g to as much as 62,2708 % , 1 g weight as much as 79,9048 %, while the weight of as much as 2 g 101,7232 %. From the results of the assay of calcium gluconate with a sample of 6,2084 g drying results have percentage 101,7232 % with the results of testing the melting point is 2000 C calcium gluconate. It can be concluded natural limestone hill Tui Leopold has a high purity calcium levels that can be made of calcium gluconate.

Efek Jus Terung Pirus (Cyphomandra betacea Sendtn.) Terhadap Jumlah Sel Darah Merah (Eritrosit) Dan Nilai Hematokrit Pada Mencit Putih Jantan Yufri Aldi; Yanelita Vipri; Zet Rizal
Jurnal Farmasi Higea Vol 5, No 1 (2013)
Publisher : STIFARM Padang

Evaluation about the effect of pirus juice (Cyphomandra betacea Sendtn.) on hematology parameters (red blood cells, reticulocytes, hemoglobin and hematocrit) for male white mice has been done. The juice was administrated orally one times a day during 20 days. The 1th day until the 20th day the animal induction with Chloramphenicol 130 mg / kg orally, followed by the provision of pirus juice with various doses of 0.26 mL and 0.52 mL. The effect was observed on day 5, 10, 15, 20, 25 and 30. The result showed that administration of pirus juice can increase the number of red blood cells, reticulocytes, hemoglobin and hematocrit male white mice at each dose is highly significant (p <0.05). Dose of 0.52 mL of the nicest effects compared with other doses (p <0.05).

Pengaruh Pemberian Kombinasi Jahe Merah, Bawang Putih, Apel, Lemon Dan Madu Terhadap Kadar Kolesterol Total Dan Histopatologis Pembuluh Darah Aorta Jantung Tikus Putih Jantan Ifora Ifora; Surya Dharma; Diken Maywidia Darma
Jurnal Farmasi Higea Vol 8, No 2 (2016)
Publisher : STIFARM Padang

Study of the effect of red ginger (Zingiber officinale Roscoe), garlic (Allium sativum L.), apple (Malus domestica Borkh.), Lemon (Citrus limon (L.) Osbeck and honey have been carried out on total cholesterol levels by using the tool Easy Touch GCHb and histopathologic examination aorta in male rats.The combination dosage were given orally for 28 days with a dose of red ginger 0.162 g / 200 g, garlic 0.09 g / 200 g, apples 1.8 g / 200 g, lemon 50 mL / 200 g, and the honey of 1.8 g/ 200 g. The data were analyzed by one-way ANOVA followed by Duncan test.The results showed a decrease in total cholesterol levels may affect histopathologic aorta is extensive aortic lumen of blood vessels and blood vessel damage scores were significant (P <0.05), which means the provision of a combination of red ginger (Zingiber officinale Roscoe), garlic (Allium sativum L.), apple (Malus domestica Borkh.), lemon (Citrus limon (L.) Osbeck and honey can lower total cholesterol and improve lumen area and lower scores damage to the blood vessels.

Pembuatan dan Karakterisasi Ekstrak Kering Daun Salam (Syzigium polyanthum (Wight) Walp.) Harrizul Rivai; Andi Heriadi; Humaira Fadhilah
Jurnal Farmasi Higea Vol 7, No 1 (2015)
Publisher : STIFARM Padang

The research on preparation and characterization dried extract of bay leaves (Syzigium polyanthum (Wight) Walp.) has been done. The dry extract is made by adding various ratio of lactose, which is the ratio of the extract and drying with lactose ½x heavy viscous extract (F1), lactose 1x heavy viscous extract (F2), 1½ x heavy viscous extract (F3) and lactose 2x heavy viscous extract heavy (F4). Dried extract mode with F4 has better characteristics than the other formulas. The name of the extract is Extractum Syzigium polyanthum (Wight) Walp. Siccum. The extract was in the form of dry powder, light green, odor like bay leaves with a bitter flavor. Levels of water soluble extract was 80.4343% ± 3.5790%, while levels of ethanol soluble extract 26.3056% ± 3.1693%, flavonoid levels of the dried extract was 0.4198% ± 0.2767%.

Efek Pemberian Jus Buah Jambi Biji Daging Merah (Psidium guajava L.) Terhadap Aktivitas Dan Kapasitas Fagositosis Pada Mencit Putih Jantan Yufri Aldi; Widya Nengsih; Zet Rizal
Jurnal Farmasi Higea Vol 4, No 2 (2012)
Publisher : STIFARM Padang

Reasearch about the effect of feeding guava red meat juice (Psidium guajava L.) on the activity and capacity of peritoneal macrophage phagocytic of white males mice has been done. The test sample is given orally for 7 days with a dose of 0.13 mL/20g BB, 0.26 mL/20g BB and 0.52 mL/20g BB, while the control group was given only distilled water. On the eighth day the bacteria Staphylococcus aureus was injected to mice intraperitonially. Result of this experiment showed that guava juice can increased activity and capacity of macrophage (P<0.05).Psidium guava L ,phagocyticed, white mice

Efektivitas Antihiperkolesterolemia Ekstrak Etanol Dari Bagian Batang Dan Buah Tumbuhan Ciplukan (Physalis Angulata L.) pada Tikus Putih Hiperkolesterolemia Helmice Afriyeni; Sara Surya
Jurnal Farmasi Higea Vol 11, No 1 (2019)
Publisher : STIFARM Padang

Tumbuhan ciplukan (Physalis angulata. L) banyak digunakan secara tradisional sebagai obat antikanker, diabetes, hepatitis, antibakteri, malaria, anemia, obat asma dan lainnya. Tumbuhan ciplukan banyak mengandung senyawa fenol dan flavonoid yang memiliki efek sebagai antioksidan. Beberapa antioksidan yang terkandung pada tumbuhan ciplukan seperti quersetin, kaemferol dan asam fenolat dilaporkan memiliki aktivitas antihiperkolesterolemia. Penelitian ini mempelajari efek antihiperkolesterolemia dari bagian tumbuhan ciplukan yaitu batang dan buah. Hewan percobaan dibagi 5 kelompok yaituKelompok I, II dan III adalah kelompok kontrol yaitu kontrol positif yang diberi MDLT, Kontrol negatif hanya diberi makanan standar dan NaCMC 0,5% dan kontrol pembanding yang diberi MDLT dan simvastatin dosis 1,8 mg/200g bb. Kelompok IV adalah kelompok yang diberi MDLT dan ekstrak batang sedang kelompok V adalah kelompok yang diberi MDLT dan ekstrak buah tumbuhan ciplukan. Kelompok IV dan V masing-masingnya diuji dengan tiga variasi dosis yaitu dosis 200, 400 dan 800 mg/kgBB. Hasil penelitian menunjukkan ekstrak batang tumbuhan ciplukan sangat signifikan dalam menurunkan kadar kolesterol total, trigliserida dan LDL plasma tikus percobaan, sedang ekstrak buah sangat signifikan dalam meningkatkan HDL plasma tikus percobaan.

Karakterisasi Flavonoid Antioksidan Dari Daun Jambu Biji (Psidium guajava L.) Harrizul Rivai; Lisa Putriani; Mahyuddin Mahyuddin
Jurnal Farmasi Higea Vol 2, No 2 (2010)
Publisher : STIFARM Padang

Flavonoid compounds have been isolated from guajava leaf from 100 grams of dried samples of guava leaf were obtained liquid extract 130 mL, n-hexane fraction as much as 1.65 g, 1.95 g of chloroform fraction, fraction of 1.87 g ethyl acetate, butanol fraction of 2.15 g, and the remaining fraction as much as 28.96 g and flavonoid A as much as 36.9 mg. Flavonoid A is a yellow amorph form and decompose at a temperature of 190-192 C. Based on ultraviolet spectrum with various reagents shear and infrared spectrum, these compounds are known as flavonol-3-O-diglukosida. Flavonoids A provide antioxidant activity with the percent inhibition of 85.364% ± 0.2073%, while the flavonoid B 68.160%, ± 0.2073.

Pengaruh Lama Pencucian Terhadap Kadar Vitamin B1 Pada Beras Putih Dan Beras Merah Secara Spektrofotometer Visibel Roslinda Rasyid; Anisa Nurul Fitria; Humaira Fadhilah
Jurnal Farmasi Higea Vol 6, No 2 (2014)
Publisher : STIFARM Padang

A research about analysis of vitamin B1 on the effeccts of long leaching on levels of vitamin B1 on white rice and red rice using UV-Visible spectrophotometry. Vitamin B1 reacted with bromthymol blue for compose ion-association complex. For improve solubility of Vitamin B1 complex compounds with bromthymol blue be added polivinyl alcohol as a solubilization substance, and added amonia buffer as pH buffer, that measured with wavelength of maximum absorbance was 431,0 nm. Average (%) Vitamin B1 level of white rice after leaching minutes 1 is 0,0166. Average vitamin B1 level of red rice after leaching minutes 1 is 0,0262. The highest level of vitamin B1 from the white rice and red rice was found on minute 1 after leaching. From the statistical analysis one way ANOVA using SPSS 17 program found a significant difference (p<0,05) from each sample.

Page 12 of 35 | Total Record : 347

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