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INDONESIA
Medical and Health Science Journal
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
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Articles 5 Documents
Search results for , issue "Vol 9 No 2 (2025): AUGUST" : 5 Documents clear
Histopathological Analysis of Endometrial Biopsies in Abnormal Uterine Bleeding: A Cross-Sectional Study Across Age Groups. Rangappan, Ashwini; Roopa A N; Sharmila P S
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.7619

Abstract

Background: Abnormal uterine bleeding (AUB) is a common gynecological complaint among women of reproductive and perimenopausal age, often indicating a wide range of underlying endometrial pathologies. Histopathological examination of endometrial tissue remains the gold standard for determining its etiology and guiding management. Objective: This study aimed to analyze the histopathological patterns of endometrial biopsies in patients presenting with AUB and to correlate these findings with different age groups. Methods: A cross-sectional study was conducted on women presenting with AUB who underwent endometrial biopsy over a defined study period. The specimens were processed and examined microscopically, and histopathological diagnoses were categorized as proliferative, secretory, hyperplastic, atrophic, or neoplastic changes. Data were analyzed according to age distribution and menstrual status. Results: The majority of AUB cases were observed in the perimenopausal group (41–50 years). The most common histopathological finding was proliferative endometrium, followed by secretory and simple hyperplasia without atypia. Endometrial carcinoma and atypical hyperplasia were more frequent in women above 50 years of age. Atrophic and disordered proliferative patterns were also seen in the postmenopausal group. A significant association was found between age and the type of endometrial pathology (p < 0.05). Conclusion: Histopathological evaluation of endometrial biopsies provides critical insights into the etiology of AUB across age groups. Proliferative and hyperplastic changes dominate in perimenopausal women, while malignant lesions are more common in postmenopausal patients. Routine endometrial sampling in AUB cases, particularly among older women, is essential for early detection of premalignant and malignant conditions.
Improving Diabetic Neuropathy Knowledge in an Urban Elderly Population: A Community-Based Intervention Study Ardian, Laurentius Johan; Santoso, Aktaruddin Arief; Fahma, Hilmia; Gusyono, Anoraga Mona Cinta Gadis Cantika; Verbimanto, Satria Fudi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.7974

Abstract

Background: The global population is aging rapidly, with older adults increasingly affected by chronic conditions such as diabetes mellitus. In Indonesia, diabetes among the elderly poses a significant public health concern, often complicated by under-recognized conditions like diabetic neuropathy. Aim: This study aimed to assess the effectiveness of a community-based intervention focused on targeted health education on diabetic neuropathy among elderly residents in urban area. Methods: A pre- and post-test design was used to assess the intervention's effectiveness. In collaboration with local health cadres and facilities, participants completed identical questionnaires on diabetic neuropathy before and after the health education session to measure improvements in knowledge. Results: A total of 143 elderly participants (median age: 65 years) were enrolled, with 73.4% being female. Post-education test scores showed a statistically significant improvement compared to pre-test scores (p<0.001p<0.001, Wilcoxon test). Of the participants, 22.4% were newly identified as having diabetes, and another 22% fell into the prediabetes range. Despite some variations in learning outcomes, 84.6% showed improved scores, indicating high effectiveness of the health education session. Conclusion: This study demonstrates that a community-based approach combining early diabetes screening and health education significantly improves elderly participants' knowledge about diabetes and diabetic neuropathy.
Effects of Kratom (Mitragyna speciosa) Hydrogel Application on Pancreatic Histopathology in Type 2 Diabetic Mice Muhammad Aqil Siroj Jazuli; Ismail, Zainul Hadi Wildan; Rihhadatulays, Khuzaimah Nur Juhanifah; Hanafi, Eka Satria Akbar Ferdinan; Jinan, Puspita Rahmatul; Pramesti, Rosandhy Alifyah; Salim, Hotimah Masdan; Bintarti, Tri Wahyuni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8018

Abstract

Background: Type 2 diabetes mellitus is a metabolic disorder characterized by elevated blood glucose caused by insulin resistance and impaired insulin production by pancreatic β-cells due to oxidative stress. Kratom (Mitragyna speciosa) has been widely investigated for its antidiabetic, anti-inflammatory, and antioxidant effects, attributed to its alkaloid, flavonoid, phenolic, and saponin contents. This study aimed to evaluate the potential of topical kratom hydrogel as an innovative approach to improving pancreatic histology in type 2 diabetic mice, which has not been previously reported. Methods: Fifteen mice were divided into three groups: untreated diabetic group (DM), diabetic group treated with 5% kratom hydrogel (K5), and diabetic group treated with 15% kratom hydrogel (K15). Treatments were administered for two weeks. Parameters assessed included the percentage of healthy β-cells and acinar cells, as well as histological scoring of islet damage. Data were analyzed using parametric or non-parametric tests according to the normality distribution of each parameter. Results: Administration of 5% kratom hydrogel significantly increased the percentage of healthy β-cells (p<0.05) compared with 15% kratom hydrogel, which unexpectedly showed a lower proportion of healthy cells than the untreated group. Interestingly, the higher dose appeared to exert more toxic effects, whereas the lower dose provided better protective effects. No significant differences were observed in acinar cell parameters or islet damage scores, possibly due to the limited sample size. Conclusion: These findings provide preliminary evidence supporting the systemic therapeutic potential of topical kratom hydrogel, particularly in determining the effective dose and the need for larger sample sizes to obtain more consistent outcomes.
Infodemiology of Anthrax in Indonesia: Insights from Google Trends (2014–2024) Fadhillah, Risti Sifa'; Utami, Putri; Sarkowi, Widya Khairunnisa; Iryawati, Dinda
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8008

Abstract

Background: Anthrax remains a persistent zoonotic disease in Indonesia, with recurrent outbreaks reported in endemic provinces such as Yogyakarta, Gorontalo, Central Java, and East Nusa Tenggara. Outbreak control is further challenged by the circulation of misinformation, which shapes community perceptions and undermines prevention efforts. Digital epidemiology offers opportunities to complement conventional surveillance by capturing public information-seeking behavior, yet its application in anthrax research in Indonesia remains limited. Methods: This study analyzed temporal and spatial dynamics of public interest in anthrax using Google Trends data from January 2014 to December 2024. Two search terms, antraks (Indonesian) and anthrax (English), were examined to assess monthly patterns, regional distribution, and related search queries. Descriptive analyses were performed to identify peaks of interest, geographic differences, and themes of related and rising queries. Results: Overall search activity was low and stable throughout the 11 years, with distinct peaks corresponding to outbreaks, most notably in July 2023 during the Yogyakarta outbreak. Regional analysis revealed Yogyakarta and Gorontalo as the dominant provinces of search activity. Linguistic patterns showed that antraks was more widely used in western Indonesia, while anthrax was relatively more frequent in eastern provinces. Related queries reflected demand for basic knowledge of symptoms, transmission, and prevention, while rising queries aligned with outbreak-related events. Conclusion: Online search patterns mirror epidemiological risk, cultural context, and digital access. Infodemiology provides timely insights that may enhance outbreak preparedness and risk communication. Integrating digital surveillance with conventional monitoring can support more effective and locally relevant health education strategies for anthrax control in Indonesia.
Prevalence, Risk Factors, and Management of Hansen’s Disease in Indonesia: Evidence from A Systematic Literature Review Sinantryana Widyaswari, Meidyta; Veterini, Lysa; Masdan Salim, Hotimah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8020

Abstract

Background: Hansen’s disease (leprosy) continues to be a public health concern in Indonesia, which ranks among the countries with the highest case numbers globally. Despite national control programs, the detection of new cases and disability rates suggests ongoing transmission and delays in diagnosis. A clearer understanding of prevalence, risk determinants, and management approaches is critical to strengthen interventions. Methods: A systematic literature review was performed using PRISMA guidelines. Relevant studies published between 2014 and 2024 were identified from PubMed, Scopus, and Google Scholar. Eligible publications included original research or program evaluations conducted in Indonesia. From 423 records initially screened, 76 full texts were assessed, and 22 articles met the inclusion criteria. Extracted data included prevalence, associated risk factors, and management strategies. Results: The reviewed studies originated from multiple regions such as Java, Sulawesi, Papua, and Maluku. Study designs comprised cross-sectional surveys, case–control studies, cohort analyses, and program evaluations. Prevalence varied substantially, with Papua, Sulawesi, and Maluku reporting the highest burdens. Commonly reported risk factors were poverty, overcrowded housing, malnutrition, genetic predisposition, and persistent social stigma. Household exposure and treatment delay were additional contributors to transmission. Management strategies mainly emphasized multidrug therapy (MDT) adherence, disability prevention, and stigma reduction. Community education and early case detection programs were associated with improved outcomes. However, several barriers remain, including incomplete adherence, inadequate health worker training, and limited psychosocial support. Conclusion: Hansen’s disease in Indonesia remains endemic in several provinces and is shaped by interconnected socioeconomic and biological factors. While MDT has reduced transmission, substantial gaps exist in disability prevention and stigma management. Enhanced surveillance, improved early detection, and stronger integration of community-based and psychosocial strategies are urgently needed to support national and global elimination goals.

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