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Jurnal Riset Sains dan Kimia Terapan

jrskt
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Published by Universitas Negeri Jakarta

ISSN : 23028467 EISSN : 23030720 DOI : https://doi.org/10.21009/JRSKT.

Core Subject : Science,

Chemistry

Jurnal Riset Sains dan Kimia Terapan (JRSKT) is the journal for the publication of original studies and occational reviews in the field of science and applied chemistry. It is published electronically two times a year

Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)

Articles 110 Documents

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Studi Variasi Suhu dan Kosentrasi Larutan Asam Sitrat terhadap Karakteristik Silika Daun Tebu menggunakan Metode Leaching Abustiana, Rahma Lolita; Mirzan, Muhamad; Sosidi, Husain; Khairuddin; Ridhay, Ahmad; Jusman
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 1 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 1, Juni 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.111.04

Telah dilakukan penelitian tentang studi variasi suhu dan konsentrasi larutan asam sitrat terhadap karakteristik silika daun tebu menggunakan metode leaching dengan 3 variasi suhu 60ºC, 80ºC, 100ºC dan 3 variasi konsentrasi 8%, 10%, 12%. Metode yang dilakukan ialah preparasi daun tebu, sintesis silika daun tebu menggunakan metode leaching dengan asam sitrat, dan pembakaran daun tebu hasil leaching asam sitrat. Pengujian dilakukan untuk memperoleh silika murni. Tujuan dari penelitian ini adalah untuk mengetahui variasi suhu dan konsentrasi larutan asam sitrat terhadap karakteristik silika daun tebu yang diperoleh dengan metode leaching. Hasil penelitian diperoleh 3 analisis yaitu, untuk analisis XRD menunjukan didapatnya hasil struktur silika yang masih amorf. Analisis FTIR menunjukan gugus fungsi yang terbentuk yaitu -OH, Si-O-Si dan Si-O. Analisis SEM menunjukan bahwa semakin tinggi suhu leaching yang diberikan terhadap sampel maka ukuran butir semakin merata.

Potential of the Ethyl Acetate Extract of Kesambi (Schleichera oleosa) Bark as an Ointment-Based Treatment for Skin Diseases Against Staphylococcus aureus Juliandoz; Dzulhijar; Sekar Ayu Ningrum; Boima Situmeang; Nani Yulianti; Nurhayati Bilangi; Weny Junus Abdul Musa; Mervina Rondonuwu
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.03

One plant with potential to treat skin diseases is the Kesambi plant. Based on community experience in Cilegon, a decoction of Kesambi tree bark has been used to treat skin ailments, including itching, insect bites, and scabies. This research aims to reveal the potential of ethyl acetate extract from the tree bark as a standardized ointment preparation. Extraction was performed using the maceration method. Quality testing of the ointment included antibacterial, safety, stability, organoleptic, and bioactive compound content testing. The best formulation was formulation 1, with an antibacterial inhibition zone of 0.6-0.7 mm, classified as moderate. Increasing the amount of extract did not significantly affect antibacterial activity. The bioactive compound content in the ointment consisted of compounds from the groups of triterpenoids, steroids, phenolics, and flavonoids.

Chemical and Physical Assessment of Water Quality in the Panimbang River Estuary, Pandeglang, Indonesia Feni Mustika Sari; Mochamad Fajar Deliaz; Akbar Rizqi Kurniawan; Yossy Ayuliansari; Riskia Chandra Widianti
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.06

The Panimbang River in Pandeglang, Indonesia, is widely used by residents for daily activities. This study analyzed water quality using physical parameters, including pH, temperature, dissolved oxygen (DO), Total Dissolved Solids (TDS), TSS (Total Suspended Solids), salinity, and alkalinity. Samples were taken around the estuary, which is surrounded by settlements. The results showed a pH of 4.50–6.49, below the standard of 6–9, indicating slightly acidic water. High temperatures, thought to be due to daytime sampling, affect DO. The average DO value was only 2.96 mg/L, well below the minimum threshold of 5 mg/L, indicating poor aeration. The average TDS is above 1000 ppm, indicating pollution from household waste and human activities. The average alkalinity of 384.976 mg/L CaCO₃ is within the safe range (30–500 mg/L), so it can stabilize pH. The water quality in the Panimbang River Estuary indicates environmental pressure from anthropogenic activities, resulting in slightly acidic water with low aeration and high solute content. However, adequate alkalinity still helps maintain the water's pH stability. This condition indicates the need for more intensive monitoring and waste management to protect estuarine ecosystems, which are vital to the community and the surrounding environment.

Synthesis of Nd-Pheophytin Complex and Its Hydrolysis into Nd-Pheophorbide from Katuk Leaves (Sauropus androgynous (L.) Merr) Fadia Novayanti; Adhitiyawarman Adhitiyawarman; winda rahmalia
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.02

Pheophorbide, as a chlorophyll derivative, has potential as a complexing ligand for heavy metals, including lanthanides. The synthesis of Nd-pheophytin complex and its more polar Nd-pheophorbide (pheophytin’s hydrolyzed product) were investigated using pheophytin isolated from Katuk’s (Sauropus androgynus L. Merr.) leaves. This study aims to determine the optimal reaction conditions and the complex characteristics. Pheophytin ligand and Nd were complexed under two different reaction conditions: room temperature and reflux at 65 °C for 10 hours. The pheophytin starting material was obtained by preparative thin-layer chromatography (PTLC), yielding 0.02 g. UV-vis analysis revealed characteristic absorption bands at 404 nm (Soret band) and 666 nm (Q band) in methanol, while FTIR spectra confirmed the presence of functional groups corresponding to pheophytin. The Nd-pheophytin complex formation was indicated by hypsochromic shifts in UV-vis spectra, suggesting the Nd³⁺ complexing. Fluorescence spectra between pheophytin and Nd-pheophytin showed distinct emission patterns, with pheophytin exhibiting peaks at 662 and 722 nm, while Nd-pheophytin displayed peaks with shoulders at 654 and 714 nm. Hydrolysis of Nd-pheophytin using 1 M NaOH at pH 10 produced Nd-pheophorbide. TLC analysis showed a decrease in the Rf value of Nd-pheophytin to Nd-pheophorbide from 0.95 to 0.43, with tailing, attributed to the higher polarity of pheophorbide. These findings confirm the successful synthesis and hydrolysis of the Nd-pheophytin complex.

The Potential of Activated Carbon from Durian (Durio Zibenthius) Peel Waste As An Adsorbent Of Oil Spill Yulyani Nur Azizah; Nur Azizah Dwi Ningrum; Nurhasni
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.01

Oil exploration activities, such as ship loading and unloading, can lead to oil spills at sea, as can oil spills and tanker collisions. An affordable method for dealing with these spills is adsorption using activated carbon derived from bio-waste, such as durian peel. This study aims to evaluate the adsorption efficiency of durian peel-activated carbon on oil spills. The carbonization of durian peel was carried out at 300 °C and activated with KOH at 5, 20, 35, and 50% (w/v). Durian peel activated carbon with 35% KOH showed the best results for moisture content (5.442%), ash content (4.457%), bound carbon content (72.050%), and iodine adsorption (896.033 mg/g), according to SNI 06-3730-1995. FTIR measurements revealed that KOH activation did not induce significant changes in the wavenumbers of functional groups, but did increase the pore diameter, as confirmed by SEM. Its adsorption efficiency with a batch system on crude oil in simulated and real seawater reached 90.182% and 90.091%, respectively. These results suggest that activated carbon from durian peel has excellent potential as an oil adsorbent. This would increase its utility value and reduce the accumulation of biomass waste.

Screening of Bioactive Compounds of Spirulina platensis as Potential Antioxidants: An In-silico Approach Himawan Prasetiyo; Fitri Novita Nanda; Mad Rudi; Nurul Azila Razak
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.05

Oxidative stress is a significant trigger of degenerative diseases, caused by an imbalance between free radicals and the body's antioxidant defenses. This study aims to identify bioactive compounds from Spirulina platensis and to evaluate their antioxidant potential using an in-silico approach. Candidate screening was conducted using Gas Chromatography-Mass Spectrometry (GC-MS) analysis, antioxidant activity prediction, pharmacokinetic evaluation (Lipinski's Rule of Five), and ligand–receptor interaction analysis (molecular docking). GC-MS analysis identified 30 bioactive compounds across various classes, including hydrocarbons, alcohols, phenols, aldehydes, and steroids. Activity prediction showed that all compounds exhibited antioxidant potential with Pa > 0.7 and Pi > 0.3, meeting both Lipinski's criteria and drug-likeness requirements. Among them, phytol and ethyl iso-allochol were demonstrated binding energies (∆G) of –5.0 and –7.3 kcal/mol, respectively, which were lower than the natural ligand 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl) ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl) pyridin-2-amine with –8.3 kcal/mol, suggesting their potential as free radical inhibitors. The microalga S. platensis thus contains antioxidant-active compounds with promising potential for further development. However, additional evaluations through active compound isolation as well as in vitro and in vivo studies are required.

Identification and Assay of Isoniazid and Pyrazinamide in Fixed-Dose Dispersible Tablets Containing Rifampicin Using High-Performance Liquid Chromatography Citra Santikasari; Meyliana Wulandari; Shofi Nafisa Ulfa; Mirawati Siregar; Syed Azhar Syed Sulaiman
Jurnal Riset Sains dan Kimia Terapan Vol. 11 No. 2 (2025): Jurnal Riset Sains dan Kimia Terapan, Volume 11 Nomor 2, Desember 2025
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.112.04

Tuberculosis (TB) remains a major global health challenge, particularly in Indonesia, which ranks among the countries withthe highest TB burden. Fixed-dose dispersible anti-tuberculosis formulations containing rifampicin, isoniazid, and pyrazinamide are widely recommended to enhance patient adherence and minimize the risk of drug resistance. Ensuring the quality and appropriate dosage of active pharmaceutical ingredients is essential for achieving therapeutic effectiveness and maintaining TB control. This study aimed to perform routine quality assessment and regulatory compliance assays on commercialanti-TB fixed-dose combination (FDC) dispersible tablets using a reversed-phase high-performance liquid chromatography (HPLC) method as specified in the International Pharmacopoeia 2025. The HPLC system was equipped with a C18 column and used a mobile phase consisting of acetate buffer (pH 5) and methanol (94:6 v/v). System suitability testing was conducted before analysis, with %RSD values below 2%, resolution greaterthan 2.0, and tailing factors ≤ 2.0, indicating acceptable precision, selectivity, and chromatographic performance. The retention times of isoniazid and pyrazinamide were consistent with those of the reference standards, confirming identity. The assay results showed that pyrazinamide (100.3%) and isoniazid (99.9%) were within the specification limits set by the International Pharmacopoeia. These findings demonstrate that the official monograph method is suitable for regulatory-grade quality control testing of dispersible anti-tuberculosis fixed-dose combination tablets, and that the tested product met pharmacopeial quality requirements.

Molecular Docking Insights into EDTA and Tween-20-Induced Inhibition of Lysozyme in Bacterial DNA Isolation Buffers Ika Keumala Fitri; Meredith Jannaatu 'Adn; Tegar Cahya Widodo; Muktiningsih Nurjayadi; Futi Kusuma Hati
Jurnal Riset Sains dan Kimia Terapan Vol. 12 No. 1 (2026): Jurnal Riset Sains dan Kimia Terapan, Volume 12 Nomor 1, Juni 2026
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.121.03

The efficiency of bacterial deoxyribonucleic acid (DNA) isolation is a critical bottleneck in Polymerase Chain Reaction (PCR) based pathogen detection. This study investigates the potential inhibitory effects of standard lysis buffer components, including ethylenediaminetetraacetic acid (EDTA), Tris base, and Tween-20, on Hen Egg White Lysozyme (HEWL) to address the low DNA yields observed in a locally developed isolation kit. Molecular docking simulations were performed using AutoDock 4.2.6. The protocol was validated by redocking the native ligand, which established the suitability of a 60x60x60 Å grid box. The results revealed that EDTA binds with high affinity, with an intermolecular energy of -6.44 kcal/mol, and interacts with crucial anchoring residues Trp62 and Asp101. Notably, the hydrophobic tail of Tween-20 exhibited the strongest binding (-7.12 kcal/mol), penetrating the active cleft and blocking the catalytic residue Glu35. Conversely, Tris base and the hydrophilic head of Tween-20 showed weaker, less stable interactions. These findings suggest a dual-inhibition mechanism in which EDTA blocks substrate access, while Tween-20 hinders the catalytic center. This study provides a molecular explanation for the kit's reduced performance and highlights the need for buffer optimization.

Analytical Investigation of Oleic Acid Double Bond Cleavage Using Cu-BiVO4 Photocatalyst in Water/Ethanol System Using GC-MS Analysis Annisa Aulia Rahmah; Bambang Prijamboedi; Fainan Failamani
Jurnal Riset Sains dan Kimia Terapan Vol. 12 No. 1 (2026): Jurnal Riset Sains dan Kimia Terapan, Volume 12 Nomor 1, Juni 2026
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.121.02

The oxidative cleavage of unsaturated fatty acids is a promising pathway for producing value-added chemicals; however, its photocatalytic conversion remains limited by catalyst efficiency. This study investigates the performance of BiVO₄ and Cu-modified BiVO₄ (Cu–BiVO₄) in promoting the photocatalytic cleavage of oleic acid in a water–ethanol system under visible light irradiation. The catalysts were synthesized via hydrothermal and impregnation methods, followed by photocatalytic reactions for 24 h. Product distribution and transformation pathways were analyzed using GC–MS. The results show that pristine BiVO₄ exhibits limited catalytic activity, while Cu–BiVO₄ significantly enhances the formation of C14 and C16 saturated fatty acids along with various oxidative cleavage products. This improvement is attributed to enhanced charge separation and increased generation of reactive oxygen species. These findings demonstrate that Cu–BiVO₄ is a more effective photocatalyst for the oxidative transformation of unsaturated fatty acids.

Coupled Raman and FTIR Analysis of Biomass-Derived Carbon Prepared at Low Carbonization Temperature Gugus Handika; Fairuz Gianirfan Nugroho; Afina Faza Hafiyyan; Feber Valentin Br Sembiring; Neysa Azzahra; Abu Saad Ansari; Nurul Taufiqu Rochman
Jurnal Riset Sains dan Kimia Terapan Vol. 12 No. 1 (2026): Jurnal Riset Sains dan Kimia Terapan, Volume 12 Nomor 1, Juni 2026
Publisher : Program Studi Kimia Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JRSKT.121.04

Biomass-derived carbon is commonly produced at high temperatures to promote graphitization; however, understanding carbon formation at lower temperatures remains critical for applications that rely on surface reactivity rather than crystallinity. In this work, carbon obtained from oil palm empty fruit bunch (EFB) through pyrolysis at 500 °C was systematically investigated using coupled Fourier transform infrared (FTIR) and Raman spectroscopy, supported by density functional theory (DFT)-based structural interpretation. FTIR analysis reveals extensive dehydration, cleavage of aliphatic C–H bonds, and progressive loss of oxygenated functional groups, accompanied by the emergence of aromatic C=C and C–O–C linkages. Raman spectra, resolved through pseudo-Voigt deconvolution, are dominated by defect-related bands (D, D2, D3, and D4) with a broadened G band, indicating the formation of small, disordered sp2 carbon domains rather than extended graphitic lattices. DFT-assisted analysis suggests that the carbon framework is composed of interconnected polyaromatic hydrocarbon clusters incorporating residual heteroatoms and mixed sp2–sp3bonding. These results demonstrate that low-temperature pyrolysis of EFB produces a defect-rich aromatic carbon structure strongly governed by precursor chemistry, offering a viable route for tailoring functional carbon materials with abundant active sites, making it highly suitable for applications in adsorption, catalysis, and environmental remediation technologies.

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Contact Name
Yussi Pratiwi

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jrskt@unj.ac.id

Phone
-

Journal Mail Official
jrskt@unj.ac.id

Editorial Address
Universitas Negeri Jakarta

Location
Kota adm. jakarta timur,

Dki jakarta

INDONESIA