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Majalah Biomorfologi (Biomorphology Journal)
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 10 Documents
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Search results for , issue "Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI" : 10 Documents clear
BACTERIAL PATTERN AMONG SEPSIS PATIENTS IN INTERNAL MEDICINE INPATIENT WARD DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA Ilma Dzurriyyatan Toyyibah; Musofa Rusli; Juniastuti Juniastuti
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i1.2022.52-58

Abstract

Highlights:1. Bacteria remain a major cause of bacterial sepsis.2. The most common causal agent in bacterial septicaemia was the gram-positive bacterium. Abstract: Background: Bacteria remain the primary cause of bacterial sepsis. Gram-negative bacteria are the most commonly isolated from sepsis patients. However, gram-positive bacterial infections have also increased recently. Objective: To identify the pattern of bacterial infection in sepsis patients in Internal Medicine inpatient ward Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Material and Method: This retrospective study reviewed the medical records of all sepsis patients in Internal Medicine Ward Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from January 1 – December 31, 2016. All patients were divided according to bacterial species into two groups: patients with gram-positive and gram-negative infection. The collected data were statistically analyzed using SPSS ver. 16.0 to find out the frequency. Result: From 179 eligible data reviewed, there were 103 (57.5%) patients with gram-positive bacterial infection and 76 (43.5%) patients with a gram-negative bacterial infection. The major isolates of gram-positive bacteria were Staphylococcus hominins (30 isolates) and gram-negative bacteria was Escherichia coli (30 isolates), 43 isolates showed multi-drug resistant organisms; Escherichia coli ESBL 23 isolates, Klebsiella pneumoniae ESBL 3 isolates, Klebsiella oxytoca ESBL 2 isolates and Methilcillin Resistance Staphylococcus aureus 5 isolates. Conclusion: The most common causative agent in bacterial sepsis was gram-positive bacteria. The major isolated gram-positive bacteria are Staphylococcus hominis and gram-negative bacteria were Escherichia coli. The species of multi-drug resistant organisms found are Methilcillin-Resistant Staphylococcus aureus (MRSA), Escherichia coli ESBL, Klebsiella pneumonia ESBL and Klebsiella oxytoca ESBL. Among the patients with multi-drug resistant organism infection, Escherichia coli ESBL were the most prevalent one.
EFFECT OF HEATED CANOLA OIL ON AORTA WALL THICKNESS IN RATS Aziz, Mochammad Abdul; I'tishom, Reny; Rejeki, Purwo Sri; Yuliawati, Tri Hartini
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.82-88

Abstract

Highlights: 1. The use of re-heated cooking oil can give negative impact on health,  especially on the cardiovascular system. 2. Unlike other types of cooking oil, repeated heating of canola oil did not show significant change in aortic wall thickness. Abstract Background: Structural alteration of blood vessels such as formation of atheroma or changes in the thickness of vessel walls, are heavily involved in pathogenesis of cardiovascular disease. Several studies have shown that canola oil has a positive effect on such diseases by reducing LDL and cholesterol levels. However, there may be several negative impacts on reheating canola oil upon administration, similar to other oils. Although canola oil can improve lipid profiles, studies related to how canola oil alters the structure of blood vessels are limited. Objective: The aim of this study was to investigate the effect of heated canola oil on intimal-to-medial thickness (IMT) of Thoracic aorta in high-fat diet rats. Material and Method: A total of 27 rats were divided into 3 groups, the K+, P1, and P2. Rats among the three groups were given a high-fat diet for 14 days, accompanied by consumption of canola oil without heating in the P1, and with repeated heating in the P2. Thoracic aorta was taken on the 15th day and then processed into histological preparations. IMT was measured using CellSens software on a microscope with a magnification of 400. The difference between groups was tested using the one-way ANOVA test on SPSS. Result: The mean and standard deviations of each group in a row were K+ (134.96 and 21.27) P1(132.04 and 27.30) and P2 (152.05 and 31.75). There was no significant difference in IMT between groups (p >0.05). However, the P2 group showed the highest mean of IMT. Conclusion: The consumption of canola oil with or without repeated heating did not result in the changes of the IMT in rats fed with a high-fat diet.
MITIGATION OF SOIL-TRANSMITTED HELMINTHIASES RESURGENCE IN THE ERA OF COVID-19 DISRUPTION: A LITERATURE REVIEW Falah, Pilar Menara; Yani Corvianindya Rahayu; Atik Kurniawati; Yudha Nurdian
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.96-102

Abstract

Highlights: 1.    Prolonged interruptions and delays that accompany the COVID-19 pandemic have further increased the spread of STH in high-transmission areas.2.    Adaptations carried out in the context of a pandemic are able to strengthen efforts to sustain deworming programs based on primary health facilities and their integration into community-based platforms.3.    Community-based WASH activities must be continued by adjusting WASH messages to focus on preventing the transmission of COVID-19. Abstract: Background: Interruptions and postponements are influencing people's desire for soil-transmitted helminthiases (STH) services as all countries are fighting the Covid-19 pandemic. The risk of spreading STH in high-transmitting areas increases with increased disturbance. Indonesia is a compatible host country for STH because it is a tropical country. The STH impacts the population's nutrient status and disturbs their cognitive processes. Objective: To describe the issue and how best efforts had been made to mitigate the possibility of a resurgence of intestinal worms during the disruptions caused by the Covid-19 pandemic. Material and Method: Search for the most recent articles in a database of research in January 2022 on Google Scholar, Science Direct, and PubMed. Qualifying articles were then extracted and synthesized qualitatively. Discussion: The interference and postponement of the deworming control program due to COVID-19 had a tentative effect on the progress of achieving the elimination of STH as a public health problem by 2030. Conclusion: Best practices show that revitalization efforts to control STH by strengthening integrated interventions and collaborations through the expansion of POPM, PHBS, and STBM in line with COVID-19 prevention efforts with mitigation innovations shifting from controlling morbidity to terminate the transmission of STH.
THE USE OF GLUCOSAMINE AND THE INCREASE OF IOP: A LITERATURE REVIEW Wega Yusan Wira Perdana; Pirlina Umiastuti; Nabila Putri Wardhani; Amirah Jasmine; Nur Milati Bani Mostavan; Nadhilah Putri Ghaisani; Audi Salman Faza
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.89-95

Abstract

Highlights: 1. There are differences in the result of the use of glucosamine and the increase of intraocular pressure.2. There are many other factors that may contribute to the increase in the intraocular pressure other than the use of glucosamine such as races, genetics, different dose, and duration of glucosamine use. Abstract: Background: Glucosamine is an amino monosaccharide that can directly stimulate the synthesis of glycosaminoglycans in the cartilage. It has been widely used as an osteoarthritis treatment. However, several literatures show the possible side effects of glucosamine, such as increased intraocular pressure (IOP). Objective: The objective of this study was to determine if there was any correlation between the use of glucosamine and the increase in IOP. Material and Method: This was a descriptive qualitative study that implied a systematic review design. The study sample consisted of patients with osteoarthritis (OA) and glaucoma in Iran, Indonesia, Thailand, the USA, and India between 2013 and 2018. The literature search was conducted on a database (PubMed and Google Scholar) and selected using inclusion and exclusion criteria. Discussion: The research identified 5 studies on the use of glucosamine and the increase of IOP. Two articles provide significant results on the correlation between the use of glucosamine and the increase of IOP (P < 0.05). In addition, two studies showed significant IOP reduction outcomes after discontinuation of glucosamine (P < 0.05). A case series indicated an increase in IOP during the 6th month of glucosamine use but still at normal value. Conclusion: Many other factors contribute to IOP growth, other than the use of glucosamine. Therefore, a large-scale randomized clinical trial or a multicentre cohort study using the same parameters is still needed to improve the quality of the subsequent systematic review
AST TO PLATELET RATIO INDEX (APRI) AND DEGREE OF SEVERITY BASED ON CHILD-PUGH CLASSIFICATION AMONG CIRRHOSIS PATIENTS AT INTERNAL MEDICINE WARD IN A TERTIARY HOSPITAL Winanda Denis Kurniawan; Budi Widodo; Betty Agustina
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.46-51

Abstract

Highlights: 1. The Child-Pugh score is an instrument to assess the degree of severity and prognosis of chronic liver disease. 2. the rise in APRI score may predict the advance of cirrhosis stages. Abstract: Background: Simple diagnostic and screening methods are needed to assist with liver biopsy, which is not always available in local health facilities. Objective: To assess the AST-to-Platelet Count Index (APRI) as a means to predict the advance of cirrhosis stages as indicated in Child-Pugh classification. Material and Method: This research employed an observational descriptive study design to examine laboratory values such as serum AST and platelet count, which were then compared to Child-Pugh profiles among cirrhosis patients at an inpatient facility in a tertiary hospital of Dr Soetomo General Academic Hospital, Surabaya, Indonesia on 1 January – 31 December 2015. The sampling method for this research was total sampling from medical histories. Result: Data obtained were then analyzed and tabulated using the descriptive technique. As many as 191 samples were obtained, consisting of male (N=129, 67.54%) and female patients (N=62, 32.46%) with a ratio of 2.08:1. APRI score showed an increase in age, with a peak frequency of 68 patients (35.6%) in the range 50-59 years old. Male patients had a higher average APRI score (2.11) than their female counterparts (1.93). Patients from Child C were the majority in this research, consisting of 105 patients (54.9%), followed by Child B (N=65, 34.03%) and A (N=21, 10.9%). Conclusion: The proportion of patients with APRI score > 1.5 is increasing along with the degree of severity according to the Child-Pugh classification. This indicates that the rise in APRI score may predict the advance of cirrhosis stages.
MALARIA INCIDENCE IN EAST KUTAI, EAST KALIMANTAN, INDONESIA 2016: AN EPIDEMIOLOGY STUDY Oktara Geovanny Saroza; Susilowati Andajani; Indah S. Tantular
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.59-64

Abstract

Highlights: 1. Most malaria infections found in East Kutai Regency were found within the male group and had high contact with forest areas.2. Malaria infections were found predominantly in the male group aged 25 to 34 years old.3. Most of the malaria infections found were caused by Plasmodium vivax. Abstract: Background: Malaria is endemic in Indonesia and knowing the factors that are involved in malaria infection will help the development of surveillance, prevention, and disease control. Objective: This study aimed to identify the profile of malaria infection and the vectors known in East Kutai Regency, Indonesia, in 2016. Material and Method: This research was a descriptive observational study with a cross-sectional design. The sample used was taken from the 2016 annual report of The Health Office, East Kutai Regency. We evaluated malaria indicators, disease distribution, incidence (age, sex, and occupation), plasmodium species found and known vectors. Result: In 2016, there were 55 confirmed cases of malaria infection in East Kutai. The Annual Parasite Index was 0.16 per 1,000. Malaria patients were dominated by males (85.5%), aged between 25-34 years old with a mean age of 29.56 years. Most of the patients lived in Rantau Pulung (41.8%). Most of the patients had work that had high contact with forest areas (70.9%). Most of the patients were infected with Plasmodium vivax (58.2%). Identified vectors were Anopheles balabacensis which was found in Kaliorang District. Conclusion: The East Kutai Regency was classified as Low Case Incidence Area with most cases found in males of 24 to 34 years old whose work had high contact with forest areas. The identified plasmodium species were Plasmodium vivax and Plasmodium falciparum while the identified vector was Anopheles balabacensis.
AGE AND BODY MASS INDEX IN TYPE I ENDOMETRIAL CANCER GRADE Gilang Adi Firmansyah; Dyah Fauziah; Brahmana Askandar Tjokroprawiro
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.73-81

Abstract

Highlights: 1. The major risk factors for type I endometrial cancer, namely age and obesity, play a major role in the increase in this case and are thought to be related to the grade in these cancer patients.2. Type I endometrial cancer patients at Dr. Soetomo General Academic Hospital 2019-2020 are dominated by patients diagnosed at the age of 56-65 years, having an overweight body mass index (23-24.9 kg/m2).3. The patient's age and body mass index did not correlate with endometrial cancer type I grade. Abstract Background: The increase in obesity and life expectancy has contributed to type I endometrial cancer cases worldwide. Increased risk factors play a role in the increase of these cases. Objectives: To determine the relationship between age and BMI with the cancer grade. Material and Method: This research was a cross-sectional study. The data were obtained from the patient’s medical records. The sampling technique was total sampling. The analysis used was Spearman Rho correlation test for the relationship between age and BMI with cancer grade. Results: This study recorded 54 patients with type I endometrial cancer in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2019 to 2020. The patients were from the age group 56-65 years 25 patients (46.30%), 46-55 years 17 patients (31.48%), 36-45 years 8 patients (14.81%), 26-35 years 2 patients (3.7%), and >65 years 2 patients (3.7%). For BMI, the patients were overweight (23-24.9 kg/m2) 21 patients (38.89%), normal (18.5-22.9 kg/m2) 14 patients (25.93%), obesity (25-29.9 kg/m2) 12 patients (22.22%), and obesity II (≥30 kg/m2) 7 patients (12.96%). For grade, grade III were 22 patients (40.75%), grade II  20 patients (37.04%), and grade I 12 patients (22.22%). There was a weak, insignificant positive correlation between age with grade (ρ=0.116, 0.405>α=0.05) and a weak, insignificant negative correlation between BMI with grade (ρ=-0.206, 0.135>α=0.05). Conclusion: A total of 54 patients with type I endometrial cancer at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2019-2020 aged 56-65 years and overweight (23-24.9 kg/m2) with grade III cancer. The patient's age and BMI did not correlate with the patient's grade.
EXPOSURE TO GOAT BILE FOR 28-DAYS CAUSES HEPATOCYTE INJURY: A HISTOPATHOLOGICAL STUDY Rizki Isnantono Prabowo; Nurina Hasanatuludhhiyah; Nily Sulistyorini; Kusuma Eko Purwantari
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.65-72

Abstract

Highlights: 1. Bile consumption, especially goat bile, is believed to have therapeutic effects even though it contains harmful ingredients that can cause toxic effects on the liver2. The administration of goat bile for 28 days had a toxic effect on the liver of the mice based on histopathological findings Abstract: Background: Bile consumption by Indonesians is believed to have therapeutic effects, especially goat bile. Goat bile is thought to contain harmful ingredients that can cause toxic effects on the liver. However, the 28-days oral toxicity study of goat bile has not been performed. Objective: To analyze the hepatotoxic effect of subchronic administration of goat bile on the liver of mice (Mus musculus). Material and Method: This was an experimental research with a post-test-only control group design. The samples used were 32 Balb/C mice (Mus musculus), which were grouped into 4 groups. The samples were administered with goat bile orally (3.2, 6.4, or 12.8 mL/kg/day) for 28 days. The liver was taken for histopathological examination and the hepatocytes injury score was performed. The scoring results were analyzed using Kruskal-Wallis, Mann-Whitney, and Spearman correlation tests (p<0.05). Result: Goat bile administration was associated with hepatocyte injury (p= 0.004). Groups with goat bile administration of 6.4 and 12.8 mL/kg/day had significant differences with the control group (p= .015 and .029 respectively) and the 3.2 mL/kg/day administered group (p= 0.006 and 0.009 respectively). Moreover, the increased administration of goat bile had a positive correlation with the level of hepatocyte injury (p= 0.004 and r_s= 0.504) Conclusion: Goat bile administration for 28 days had a significant toxic effect on the liver of mice at a dose of 6.4 mL/kg/day.
Front Matter Vol. 32 No. 2 July 2022 Majalah Biomorfologi
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.%p

Abstract

Back Matter Vol. 32 No. 2 July 2022 Majalah Biomorfologi
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.%p

Abstract

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