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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
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Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16802

Abstract

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Investigation the Role of IL-17 rs2275913 Gene Polymorphism with the Risk of Osteoporosis in a Sample of Iraqi Pre and Postmenopausal Women Asmaa Mahmoud Salman; Da'ad A. Hussain
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16804

Abstract

Objective: This study aimed to investigate the relationship between the genetic polymorphism and allelesfrequencies of IL-17 rs2275913 G/A with the risk of low bone mineral density (osteoporosis and osteopenia).Furthermore studying the relation between some immunological and biochemical parameters with thisdisease in a sample of Iraqi pre and postmenopausal women. Methodology: In this study, we investigatedabout the IL-17 rs2275913 G/A polymorphisms and the risk of low bone mineral density (BMD) among30 patients with osteopenia, 30 patients with osteoporosis and 30 healthy controls. Serum IL-17 level andits correlation with the IL-17 rs2275913 G/A genotypes were analyzed. The study was carried out fromNovember 2020- January 2021 in Baghdad Teaching Hospital/ Bone density examination unit/ in Baghdad-Iraq. Conclusion: It is concluded that the IL-17 rs2275913 G/A genotype was not associated with increasedrisk for development of low (BMD) in Iraqi pre and postmenopausal women. Recommendation: Based onstudy conclusion, during menopause, it is important for women to have a DEXA scan to detect low BMDand receive appropriate care to prevent degradation of the micro-architecture of bone tissue, which increasesthe risk of bone fractures.
Treatment of Lupus Nephritic with Severe Preeclampsia: A Case Report Asri Insanur Rahma; Lita Diah Rahmawati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16805

Abstract

A 25 years-old pregnant woman with history of Systemic Lupus Erythematosus (SLE) complained shortnessof breathing and swelling legs. Physical examination showed hypertension, tachycardia, tachypnea,anemic conjunctiva, and pitting edema in both legs. Workup examination found anemia, hypoglycemia,hypoalbuminemia, proteinuria, metabolic acidosis, strong positive dsDNA, trivial MR, mild TR, PR, dilatedLV, decrease of LV systolic function, hypokinetic global LV, eccentric LVH, and severe oligohydramnios.The patient was diagnosed with severe preeclampsia, severe oligohydramnios, SLE, Lupus Nephritic (LN),stage II JNC VII hypertension, and peripartum cardiomyopathy.An emergency caesarean section was planned as the main management to prevent infant and maternalmorbidity and mortality. MgSO4 was given to prevent eclampsia. Methylprednisolone and azathioprinewere given to control SLE and LN activity. Furosemide, spironolactone, ramipril, methyldopa and nifedipinewere given to control blood pressure, help normalizing heart function, and prevent organ failure. The patientwas suggested to postpone next pregnancy until 1 year after LV function turns to normal.
Knee Osteoarthritis Severity in Relation to Neutrophil- Lymphocyte Ratio Auday Hussain Hassan Al-Janaby
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16806

Abstract

Background: Osteoarthritis is a disease with a significant inflammatory component. Neutrophil-lymphocyteratio (NLR) level is a marker to determine inflammation. The study aimed to evaluate the association betweenseverity of knee osteoarthritis and NLR.Methods: A case-control study conducted inAl-Zahrawiduring June 2017 to June 2018. A total of 100 kneeosteoarthritis were recruited and 50 healthy subjects as a control group.Results: NLR was significantly higher in knee osteoarthritis than controls, the mean vale was (2.19±0.72)and (1.97±0.88), respectively. Older age, chronic pain, prolong onset of diagnosis and high NLRweresignificantly associated with severe osteoarthritis.Conclusions: Knee osteoarthritis had higher NLR compared to healthy people. Higher NLR is associatedwith severity of knee osteoarthritis and it is a poor indicator.
Bronchodilator Effect of Crataegus azarolus var aronia Unripped Fruit Extracts on Rat’s Tracheal Smooth Muscle Aveen A. Mohammed; Omar A. M. Al-Habib
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16807

Abstract

Objectives: The present study aimed to investigate the bronchodilator effect of different Crataegus azarolusvar aronia unripped fruit extracts on tracheal smooth muscle of rats and to study the roles of K channels andEDHFs in produced responses.Background: Crataegus is widely used in Kurdistan Region for the prevention of several diseases suchas respiratory, cardiovascular, hypertension …. etc. due to its content of several bioactive compounds likearomatic amines, phenolic acid, flavonoids, and proanthocyanidins.Method: The bronchodilator effects of various Crataegus fruit’s extracts on rat’s tracheal rings and the rolesof K+, Ca2+ channels and EDHFs in bronchodilation using specific blockers.Results: Most of Crataegus fruit’s extracts used showed a potent bronchodilator effect on trachea, in whichthe HME produced a highly significant dilation, followed by methanol and ethyl acetate extracts whichshowed a considerable relaxant effect. The results confirmed that the induced dilation was NO and PGI2dependent, along with activations of KATP and Kir and Kca while Kv plays a minor and limited role.Conclusion: The novel results indicate that HM, M, EA extracts prepared from Crataegus unripped fruitproduce a potent bronchodilator effect, which was NO and PGl2 dependent along with the activation of KATP,Kir and Kca2+ channels.
Deleted Aya Yaseen Mahmood Alabdali; Sasikala Chinnappan; Basma M. Abd Razik; Mogana R; Shaik Ibrahim Khalivulla; Rahman H
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16808

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Effect of Murotal Sound Stimulation during Pregnancy on the Number of Neuron Cells of Cerebrum and Cerebellum of the Newborn Rattus norvegicus Ayu Putri Yani; Hermanto Tri Joewono; Widjiati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16809

Abstract

Background: The human development index (HDI) illustrates how superior human resources are. Thestimulation of Murotal during growth and development has been shown to increase cell growth in plants.The aim of the study was to analyze the effect of the differences againts the number of neuron cell’s in thecerebrum and cerebellum Rattus norvegicus offspring between those who received Al-quran Murottal surahAr-Rahman stimulation, Qori and Qoriah sounds voice in pregnancy day of 6th. Methods: An Experimentalstudy using 30 pregnant (Rattus norvegicus). Subjects were randomized into three groups, control group(Q1), voice of Qori group (Q2), and voice of Qoriah group (Q3). sound stimulation was given on 6th-17thdays of pregnancy. From each mother, two Newborn of Rattus norvegicus were taken to make preparationsfrom brain tissue. Eosin Hematocycline was performed to assess number of neuron cells. Results : Thestudy shows that the mean and standard deviation of the number neuron cells cerebrum and cerebellum inthe control group is 9.88 ± 1.71 and 21.10 ± 2.11, the voice qori group is 10.16 ± 1.01 and 22.46 ± 1.71,and the voice qoriah group 11.12 ± 1.52 and 22.50 ± 1.76. ANOVAs statistical test results show there isno significant differences among groups with a value of p = 0.152 in the cerebrum and p=0.183 in thecerebellum. Conclusion : Murotal sound stimulation during pregnancy increased the number of neuron cellsin the cerebrum and cerebellum of newborn rats.
Acute Aerobic Exercise Decreased Tumor Necrosis Factor Alpha Bana Yusrian Hawari; Sugiharto; Desiana Merawati; Adi Pranoto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16810

Abstract

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Hand Hygiene Compliance Behavior and Glove Use in the Pediatric Intensive Care Unit During COVID-19 Pandemic Bangkit Putrawan; Dominicus Husada; Parwati Setiono Basuki; Risa Etika; Ismoedijanto; Dwiyanti Puspitasari; Leny Kartina
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16811

Abstract

Background: The condition of Covid-19 pandemic potentially influences hand hygiene compliance as aresult of workload changes, increased awareness of healthcare workers (HCWs) and personal protectiveequipment procedures, especially in terms of hand glove use,Objective to know the adherence of healthcare workers at the pediatric intensive care unit (PICU) to complywith hand hygiene and glove use during the pandemic.Methods An observational prospective study was carried out including all HCWs stationed at the PICU DrSoetomo General Hospital during January 2021. All participants were to sign an informed consent beforethe study took place. A target of 500 opportunities was estimated during the observation, and recorded usinginfra-red cameras placed at ten points. Hand hygiene compliances were evaluated according to the videosurveillance records by an independent auditor. Compliance was measured by dividing total number ofobserved appropriate hand hygiene by the sum of opportunities. Data were analysed using Chi Square testat a significance of p<0.05.Results: A total of 28 HCWs were eligible for the study; 9 were excluded. The majority were female(21; 75%), the mean age was 37.9 (SD 5.2) years. During 72 hours’ observation among 526 glove-useopportunities 104 (19.7%) actual glove-use episodes were evident. The hand hygiene compliance was lower(41.3%) when wearing gloves as compared to those with no glove use (68.2%) (p<0.001).
Assessment of Self-care Among Elderly Residents at Nursing Homes in Middle Euphrates Cities in Iraq Bashaer Mohsen Ali; Ali Kareem Al-Juboori
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16812

Abstract

Self-care is known to be a health resource in later life because it enables the elderly to improve theirhealth and live at home as long as possible(1). It is therefore essential to resolve the question of self-care inthe elderly(2). The aim of the current study was to assess the level of self-care among elderly residents atnursing homes and to find out the difference between level of self-care with regard to socio-demographicand clinical characteristics. Descriptive study design carried out among 60 elderly persons at nursing homesin middle Euphrates, they are selected by using non probability sampling. The study instrument composed of2 parts. 1st Elderly’s Demographic Characteristics, 2nd self-care scale. The results of study reveal the overallassessment of self-care domains was moderate. In addition, there is a high significant in difference in selfcarelevel of the elderly with regard to their age and their marital status.