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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 364   365   366   367   368 
Hemorrhagic Varicella in a 41-Year-Old Woman with Evans Syndrome : Case Report Alfina Rahma; Eka Devinta Novi Diana; Frieda; Wibisono Nugraha; Muhammad Eko Irawanto; Moerbono Mochtar
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17445

Abstract

Background: Varicella is an infection caused by the varicella-zoster virus (VZV) with symptomsof an exanthematous vesicular rash and systemic symptoms. Hemorrhagic varicella commonlyseen in immunocompromised patients. Evans syndrome (ES) is an autoimmune with two or morecytopenias,including autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP).Case: 41-year-old woman complains of swelling filled with reddish fluid almost all over herbody,sometimes painful and accompanied by fever. Patient also experienced vaginal bleeding resultingin anemia (Hb 8.8 g/DL) and thrombocytopenia (platelets 34,000/uL). Dermatological status of thegeneralized,multiple hemorrhagic vesicles with an erythematous base,partially ruptured. Tzank testrevealed multinucleated giant cells. Patient suffered AIHA and received therapy with methylprednisolone4 mg/day and mycophenolic acid 2x500 mg/day.Conclusion: We report a case of hemorrhagic varicella in a 41-year-old woman with Evan’s syndromewith concurrent features of AIHA and ITP. Dermatological status of the generalized, multiplehemorrhagic vesicles with an erythematous base,some of ruptured with erosions. Tzank test revealedmultinucleated giant cells. Patient was treated with acyclovir 5x800 mg for 7 days,2% salicylic acid and0.5% menthol applied every 12 hours and mupirocin 2% ointment applied twice a day on the erosionarea and clinical improvement was found after 17 days of therapy.
Estimation of Interleukin‐10 and Interleukin‐22 Levels in the Advances of Breast Cancer Ali Jabbar Abd Zaid Al-Kilabi; Ghada Basil Ali Alomashi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17446

Abstract

Background: Breast cancer is the secant-kind of carcinoma in women with higher incidence in Iraq.There are many prognostic and predicitive factors used for management of the breast cancer. Serumlevels of the cytokines may be utilized as a marker of immunity status and prognosis in CA breast.Aims of the Study: Measuring the IL-10 and IL-22 in breast cancer patients and association IL-10and IL-22 with stage and grade for breast cancer. Materials and Methods: The case-control studywas conducted on 60 women with CA. Breast and 60 controls group, patients with CA. Breast werereferred to Middle Euphrates cancer center in Najaf during the period November 2019-October 2020.Measurement of Interleukin-10 and Interleukin-22 by using ELISA. Results: The showed a levels ofIL-10 and IL-22 in breast cancer group higher than levels of IL-10 and IL-22 in control, and showeda high levels of IL-22 in advances stage and grade III. The showed non-significant in IL-10 levelsbetween four stages and three grade. Conclusions: A significant elevation levels of IL-10 and IL-22 inbreast cancer groups comparison with control, elevation significant IL-22 levels in stages and gradesof breast cancer.
Occupational Health Hazards among Workers at Government Garment Factory in-Al Najaf City Ali Sadoon Almusawy; Murtadha K. Adea Aljebory
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17447

Abstract

Descriptive design cross-sectional study was conducted in assess the occupational health hazards amongworkers in Al-Najaf in garment factory and its association with socio-demographic characteristics ofworkers in the province of Najaf during period from December 23th 2020 to February 9 the 2021. 180male and female workers were selected through non-probability sampling (purposive sampling) andthe data collected using the questionnaire that was designed earlier from three main parts, first partincluded socio-demographic data characteristic and the second part was included health care facilitiesthat include health services to workers and the three part (health hazards) and that consist of (physicalhazards, chemical hazards, biological hazards, psychological hazards The study found that the overallrisk score was moderate, the higher risk was for psychological risks, and the lowest risk was for safetymeasures and protective equipment, The overall hazard score was found to have a statistically significantrelationship with each job title and work location (P 0.05). Further research, as well as an educationprogram and regulations for the use of safety measures, were strongly recommended.
Relationship between Parenting Stress and Risk of Attention Deficit Hyperactivity Disorder (ADHD) in Elementary School Children Alma Rossabela Setyanisa; Yunias Setiawati; Irwanto; Izzatul Fithriyah; Satria Arief Prabowo
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17448

Abstract

Background: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorderduring child development with three symptoms which are comprised of inattention, hyperactivity, andimpulsiveness that may persist into adulthood. This condition can be a stressor for parents in performingparenting and may lead into a state of parenting stress. Objective: To analyze the relationship betweenparenting stress and the risk of developing Attention Deficit Hyperactivity Disorder (ADHD) inelementary school children. Methods: This research was conducted in Surabaya from November 2020to January 2021 with respondents consisting of parents of elementary school children who have ADHDrisk and agreed to participate in this study with a total of 55 samples selected using a purposive samplingtechnique. The research design was cross-sectional using demographic questionnaire, AbbreviatedConners Rating Scale (ACRS), and Parenting Stress Index-Short Form (PSI-SF) which were filledout by respondents through an online form. The data were processed and analyzed using One-SampleChi-Square analysis test program with a p-value <0.05, considered statistically significant. Results:The majority of parents experienced moderate parenting stress levels (58.2%). There was a significantrelationship between each level of parenting stress and the risk of ADHD in children (p < 0.001).Conclusions: There is a significant relationship between parenting stress and the risk of ADHD inchildren.
Quantitative Risk Assesment of Benzene Exposure in Printing Industry X Surabaya City Amanda Fithri Habibati; Abdul Rohim Tualeka; Juliana Jalaludin; Syamsiar Russeng; Ahsan; Puji Rahmawati
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17453

Abstract

Benzene is a compound chemically volatile and lasts a long time in the air and quicklyinhaled into the human body. The use of benzene is widely used in various industries, one ofwhich is the printing industry. Benzene produced right in the printing industry are ink, cleaning fluid,and when the machine in operation. Workers exposed to benzene can risk cancer and non-cancer healtheffects that are harmful to the human body. This study aimed to assess cancer and non-cancer risk ofworkers in the printing industry X Surabaya City. This research is observational, cross-sectional withthe same sample with a total population of 11 workers in the printing industry X Surabaya City. Therisk assessment method uses four stages: hazard identification, exposure analysis, dose and responseanalysis, and risk characterization. This research shows that the average concentration of benzene is1.0729 mg/m3 or 0.34 ppm. RQ value > 1 both real-time and lifetime. As many as 63.6% of workershave real-time ECR >10 -4, and 81.8% of workers have ECR lifetime >10-4. This study concludes thatworkers are in an unsafe condition and have non-carcinogenic and carcinogenic health risks.
Age Estimation with Cemental Incremental Lines in Normal And Periodontally Diseased Teeth Using Phase Contrast Microscope Ameena Sultana; Heena Zainab; Pramod Jahagirdar; Deepa Hugar; Shaimaa
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17454

Abstract

Background: Forensic age estimation defines an expertise in forensic medicine, which aimsto define in the most accurate way to determine the unknown chronological age of the personinvolved in judicial or legal proceedings. Dental cementum is a vital tissue which demonstratescontinuous apposition throughout the life of the tooth. Literature studies have revealed that toothcemental annulations(TCA) would serve as a reliable tool in establishing the age of an individual.The use of specialized microscopic methods are been employed to enhance the assessment ofthe cemental annulations. The study aims at assessment and evaluation of cemental annulationsin normal and periodontally diseased extracted teeth using phase contrast microscopic method.Methodology: A total of 60 teeth were included in the study and out of which thirty teeth were normaland 30 were periodontally involved teeth respectively. Longitudinal ground sections were prepared usingmicromotor and diamond disc. Sections were mounted and observed under phase contrast microscope.Measurements were made using an image analyzer software. The total width of cementum was dividedby the distance between two incremental lines. The eruption age of the tooth was then added to this toobtain the chronologic age for each individual. The results of the study showed no significant deviationof estimated age from the actual age in both periodontally sound and periodontally diseased teeth.Conclusion: The study concludes that the use of phase-contrast microscopy in conjunction with imageenhancement procedures improves the accuracy of age estimation and may serve as a reliable aid inforensic identification.
Vascular Endothelial Growth Factor (VEGF) Expression on Placenta Accreta Spectrum (PAS) FIGO Grading Ana Puji Rahayu; Agus Sulistyono; Ernawati; Grace Ariani; Rozi Aditya Aryananda
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17455

Abstract

This study aims to analyze the role of placenta VEGF level using immunocytochemical techniques andcomparing the obtained results with PAS FIGO grading. This retrospective cross sectional study ontotal sampling of formalin fixed paraffin-embedded tissue from placenta sampling of elective surgerywhich were diagnosed as PAS. Sample were immunostained using VEGF and semi-quantitativelyImmuno Reactive Score (IRS) measured based on modified Remmele scale index. The result obtained32 samples that meet inclusion criteria which are found into grade I (n=5), grade II (n=11) and gradeIII (n=16). This study showed average VEGF at grade I (4.68±1.03), grade II (3.81±1.41), grade III(4.46±1.82) and no significant difference of VEGF expression between grade I, grade II and grade III(p = 0.264). Intraplacental VEGF do not describe the severity of PAS FIGO grading.
Effects of Nutrition and Physical Activity in Prevention of Neurological and Cognitive Disorders- A Review Study Shweta Patel; Diwakar Chauhan; Ranjana Patnaik
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17457

Abstract

Background: As neurodegenerative and psychiatric disorders are rising rapidly, unexpected demandfor cost-effective and practical treatment is also growing. The present study reveals the synergistic roleand mechanism of nutrition and physical activities in the transition of cognitive functions and mentalwellbeing.Objectives: To unravel the effect of nutrition and exercise in maintaining cognitive function and mentalhealth. In this study some of these points were reviewed such as what is the influence of nutritionand exercise over mental health. How well the combined effects can help to combat neurological andbehavioural disabilities. What mechanism is involved in promoting mental health.Methods: A non-systematic approach was used in the present review study. This study summarizes thesynergistic role and mechanism of nutrients and physical exercise in the transition of cognitive functionand mental balance.Results: The most important outcome is nutritional therapy in combination with regular physicalexercise is a reliable, effective and economical alternative that can intensify the effects of standard drugtherapy.
Sexual Dimorphism and Clinical Relevance of Thickness and Angulation of Lateral Lamella of Cribriform Plate-A Multidtector Computed Tomographic Study Anandagouda V Naikanur; Balappa M Bannur; Manjula Patil; Sanjeev I Kolagi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17458

Abstract

Background: The aim of this study was to establish the morphometry and sexual dimorphism of laterallamella of cribriform plate in the North Karnataka region.Method: Six hundred and forty four (644) Multidetector computed tomographic scans were collectedfrom North Karnataka region and analyzed by using RadiAnt DICOM Viewer. The thickness andangulation of lateral lamella of cribriform plate of olfactory fossa were calculated on both the sides inboth genders. Statistical analysis was done by using Student unpaired‘t’ test.Conclusion: There was statistically significant difference in the angle of lateral lamella of cribriformplate when compared between right side (mean=106.25˚) and left side (mean=109.38˚) in males.There was no such difference among females. Statistically significant difference was observed in theangle of lateral lamella of cribriform plate in male patients (mean=106.25˚) when compared to femalepatients (mean=109.61˚). The thickness of lateral lamella of cribriform plate was not significant whencompared between two sides in males and females. Hence, these variations in the morphometry of thelateral lamella of cribriform plate of ethmoid bone will be of importance for the surgeons in Functionalendoscopic sinus surgeries and anterior skull base surgeries.
Effectiveness of Pisang Raja Peel Extract (Musa Paradisiaca L) on Bacterial Growth of Porphyromonas Gingivalis as the Cause of Periodontitis Andy Fairuz Zuraida Eva; Masriadi; Nur Rahmah Hasanuddin; Muhammad Ajis
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17459

Abstract

Background. Periodontal disease is a chronic inflammatory infection that causes damage to thetissue supporting the teeth. The most common periodontal diseases are gingivitis and periodontitis.Periodontitis is a complex, localized chronic inflammatory disease characterized by the destruction ofconnective tissue, periodontal ligaments, and bone supporting teeth. This periodontal disease is causedby plaque bacteria on the surface of the teeth, where the plaque is a thin layer of biofilm containinga collection of pathogenic microorganisms such as Porphyromonas gingivalis, Actinobacillusactinomycetemcomitans, Prevotella intermedia, Tannerella forsythia and Fusobacterium nucleatumwhich are soft deposits. Porphyromonas gingivalis is a gram-negative, black pigmented, rod-shapedanaerobic bacteria. Porphyromonas gingivalis is one of the dominant bacteria in chronic periodontitiswhich is found in subgingival plaques. Indonesia is a country with a tropical climate which makesit rich in biodiversity, which can be used as antibacterial agents. Plantain (Musa Paradisiaca L) isa fruit that is easy to get, but the skin is rarely used. The Pisang Raja peel (Musa Paradisaca L)contains chemical compounds saponins, tannins, flavonoids, and alkaloids which have antimicrobialproperties. Objective: To determine the effectiveness of Pisang Raja peel (Musa Paradisiaca L) extractagainst the inhibition of Porphyromonas gingivalis bacteria as a cause of periodontitis. Methods: Usinglaboratory experimental methods, the test was carried out in the laboratory with the form of researchin the form of Posttest Only Control Design and sampling by random sampling through 4 treatmentsand 6 repetitions. Statistical test was One Way Anova. Results: Based on the oneway Anova test, theconcentration group of 16%, 32%, and 64% and the control group obtained a p-value of (p <0.01)which means that there is a significant difference. Conclusion: Based on the results of this study, it isshown that the effectiveness of Pisang Raja peel extracts concentrations with concentration 16%, 32%,and 64% in inhibiting Porphyromonas gingivalis bacteria and control group obtained p-value (p<0,01)means there was significant correlation. Conclusion: Based on this research that there is effectivecorrelation Pisang Raja peel extract with concentration 16%, 32%, dan 64% can inhibit the growthPorphyromonas gingivalis.

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