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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
 383   384   385   386   387 
Correlation of Oral Health Status with Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital Nandita Shenoy; Alisha Ono Idris; Vishak Acharya; Junaid Ahmed; Ashok Shenoy; Suchitra Shenoy
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17724

Abstract

Background: Oral health is considered to be an important factor in respiratory diseases like Pneumonia and chronic obstructive pulmonary disease (COPD). Poor oral health and abusive habits like smoking have been implicated as an independent risk factor for the development of COPD, but few studies have evaluated the association between oral health and COPD.Aim: To assess the oral health and habits of COPD individuals visiting our OPD for their regular checkups. Subjects and Methods: We performed a case-control study of oral health among patients with COPD exacerbators and healthy non COPD controls. Cases had experienced ≥1 exacerbation in the previous 12 months, while controls were healthy patients reporting to the dental OPD for a regular dental checkup. We evaluated oral health status, recorded dental symptoms/habits, and Pulmonary Function Test (PFT). In a subset, we performed blinded dental exams to measure bleeding on probing, probing depth, clinical attachment loss, periodontitis severity, plaque index, gingival index, and carries risk. We evaluated associations between oral health and COPD using logistic regression. Result: Self-reported oral health status and objective dental findings had variations between cases and controls. Participants with COPD had multiple missing teeth, a higher amount of plaque, and calculus indicating poor dental health. Oral candidiasis, keratotic white lesions, and oral melanosis were also present. Conclusion: In the present observational study, we found that participants with COPD have poor oral health that compromised their quality of life probably precipitating an acute exacerbation. The incidence of COPD can be reduced by good oral hygiene measures and preventive oral care.
A Theoretical Study for Determination of Capoten by Analytical Methods Rana.S.AL-Shemary; Enass Najem Oubaid
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17728

Abstract

The present analysis article points out numerous analytical methods for the quantitative identification ofACE inhibitor (ACE Inhibitor) by one in all the spectroscopical techniques (UV-spectrophotometry) andseparation techniques, like superior liquid natural action (HPLC). additionally, we tend to examine thecontribution of optical biosensors to the clinical and pharmaceutical study of ACE inhibitor, which hasapplicable analytical procedures for internal control, pharmaceutical drug formulations and human.In this report, a comprehensive sample of scientific papers published in different journals relating to medicinal,clinical and analytical chemistry was collected. Captopril was chosen because it is a popular medication inthe pharmacy, a first-line antihypertensive agent, with a fast release, limited course of operation
A Comparative Evaluation of Dental Erosion Caused by Tetrapacked and Aerated Beverages: An In-Vitro study Haritha R.K; Sreeja.C; Samyukta S; Cyril Benedict.H; Nagaland.T; Sathish Muthukumar.R
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17753

Abstract

Introduction: Dental erosion is an evolving concern with the food market globalization. In a rapidlydeveloping nation as India, beverage consuming behavior has significantly increased. There is freeaccess to new foods and beverages even in the neighborhood grocery stores and they are perceived asmodern and healthy. Extrinsic erosion appears to be a growing problem as a result of overconsumptionof soft drinks or fruit juices or both. Materials and Methods: Freshly extracted premolars weretreated with H202 for 24 hours and weighed with ‘Essae FB-200’ with a readability of 0.001 gram. Thebeverages were grouped into 2 categories, 1- Natural or tetra-packed beverages, 2 - aerated beveragesand a control. 20ml of each beverage was taken and the pH was measured. The tooth was immersed ineach of the beverage and pH were noted 4th hourly for 48 hours accounting for sipping the beveragefor 5 minutes every day for 1.5 years. The weight of the tooth was rechecked after 48 hours. Results:The mean pre-treatment pH of category 1 was 5±1.33 and that of category 2 was 4.66±1.32. There isno significant difference in the mean loss of weight between the two groups (p-value 0.94) there is nosignificant difference in the mean change of pH between the two groups (p-value 0.26) Conclusion:The objective erosive liability of tetra-packed and aerated beverages on the dental enamel was foundto be similar. However, natural fruit juices showed nil to negligible objective signs of dental erosion.
Health Promotional Life Style Intervention on Knowledge and Practice Regarding Prevention of Co-Morbid Conditions and Complications of Chronic Renal Failure among Hemodialysis Ashwini Patil; Indrawati Rao; Sateesh Biradar
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17754

Abstract

Hemodialysis is the most frequent treatment method for CRF. However, it has been argued that anumber of restrictions and modifications accompany this treatment, which have a detrimental impacton the quality of patient’s life and affect individuals’ physical and psychological well-being. Objectiveof the study was to assess health promotional life style modification regarding prevention of comorbidcondition and complications of chronic renal failure among hemodialysis patient. A QuantitativeResearch approach and Quasi experimental research design (Nonequivalent control group pretest postDesign) was used for the present study. The sample consisted of 200 chronic renal failure patientsundergoing hemodialysis were selected by convenient non probability sampling technique. ResultsThe finding of the study revealed that in experimental group, pretest Knowledge mean score of thesamples had 20.26 and in posttest knowledge mean score had 33.93 so the difference is 13.67, thisdifference was large and it is statistically significant. Whereas in control group, pretest, this differencewas small and it was statistically not significant. In experimental group, mean pretest Practice scoreof the samples showed statistically significant. In experimental group 16.28% improvement in QOLscore after intervention and in control group improvement score is 0.35%. This difference showed theeffectiveness of the study. Considering correlation between experimental group posttest knowledgescore and posttest practice score was (r=0.44 P≤01), correlation between experimental group posttestknowledge score and posttest QOL score was (r=0.45 P≤01) and correlation between posttest practicescore and QOL score was (r=0.52 P≤01). It showed moderate positive correlation among them. Theresult of the present study suggest that health promotional life style modification is necessary to reducecomplications and co morbidities which is occur due to CRF and enhance quality of life of chronicpatients.
A Study on Determinants of Irritant Contact Dermatitis in the Workers of a Slaughterhouse on Jalan Abu Bakar Lambogo, Makassar Arni Juliani; Muhammad Akbar Salcha; Rizky Maharja; Helmy Gani, M. Anas; Andi Tenriola Fitri Kessi; Sitti Fatimah Rahmansyah
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17755

Abstract

Contact dermatitis, in general, is a non-infection inflammatory condition because the skin has contactwith both chemical and biological compounds. The aims of this study is to analyze determinants ofirritant contact dermatitis in the workers of a slaughterhouse. This study was analytical observationusing a cross-sectional approach. The population of this study was 93 workers of a broiler chickenslaughterhouse located on Jalan Abu Bakar Lambogo, Makassar. Data collection was by performing adirect observation and interview to the skin condition of the workers’ hands who were suffering fromthe symptoms of irritant contact dermatitis, such as skin rash, dry skin, itchy and painful skin, swollenskin, and chapped, and observing the work process of chicken slaughtering. Data were analyzed usingmultiple logistic regression analysis. The result of this study shows that the use of PPE, personalhygiene, length of employment, personal history of diseases of the skin, and duration of contact aresignificantly correlated with (p < 0.05) the incidence of irritant contact dermatitis symptoms. Basedon the result of the multiple logistic regression analysis, personal hygiene (p = 0.003) and duration ofcontact (p = 0.004) are the main determinants of irritant contact dermatitis symptoms in the workersof the broiler chicken slaughterhouse. It can be concluded that the personal hygiene and duration ofcontact are the main determinants of irritant contact dermatitis symptoms in the workers of the broilerchicken slaughterhouse.
myc Gene and Cancer Variant Analysis and Network Interaction: An In-Silico Analysis Saeed M Kabrah; Talal Qadah; Arwa F Flemban
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17791

Abstract

The myc is a proto-oncogene that regulates the cellular process like cell growth, proliferation,metabolism, apoptosis and malignancy pathologies. myc deregulation occurs in several cancers andplays a significant role in disease development, metastatic potential, and therapeutic resistance. Drugtargeting myc in cancer remains highly desirable with substantial challenges, delaying the direct myctargeted drugs’s development. These drugs target the myc transcriptions deregulations in tumours cellby compound inhibiting the inducing of epigenetic silencing or regulation of G-quadruplex structureswithin the myc promoter. Proteins involved in myc’s post-translational modulation have been identifiedas significant surrogate targets for lowering myc activity downstream of aberrant cell stimulatorysignals.
Deleted Ishita Chatterjee
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

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Effect of Pica on Some Hematological Parameters in Thi-Qar Province Haider M. AL Yasiri; Muslim N. Saeed; Ali Kadhim Shwayel Al-Saeedi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.17795

Abstract

Pica items are deferent, and vary according to culture, race/ethnicity and geographic location. It is the eatingof a non-nutritional substance as defined by the American psychiatric association and the most widespreadof which is eating soil. A total of 163 iron deficient anemic patients included in this cross sectional study,where 18 substances nominated as causes of IDA were collected from …….. . Information was collectedfrom the patient involving gender, age, type of substance, and the causes of iron deficiency were sought toidentify clinical and laboratory correlates of pica in 163 .The result show where most targeted materialsas pica was Bitter gum 81 (22.8%) while the lowest were the Sesame =1, Nail=2, Soap=1 cases. whilesignificant statistical difference between the gender distribution and hemoglobin levels, WBC of picapatient, while age and platelets don’t showing this differences. only age of (35-40) years showing significantstatistical association of both Hb and WBC counts. The result show many comorbid condition in additionto anemia had been discovered, where most of these condition where linked to Khawa clay consumptions.Independent variables seems to be correlated really through the effect of the granulocytes and platelets withHb. This study is very important as a future study because it reveals many patterns of deficiency of someblood parameters with pica, as well as most people who suffer from Pica have iron deficiency, as this studyprovided a great incentive to know the ages and genders of the most vulnerable group of pica disorder.
A Review on Novel Analytical Method Development and Validation by RP-HPLC Method Suyash Gupta; Preeti Verma; Abhinav Prasoon Mishra; Nainshi Omar; Riya Mathur
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17798

Abstract

A simple, precise, accurate, specific and RP-HPLC method was developed for determination of drug inpharmaceutical formulation. Analytical method development and validation play important roles in thedrug discovery, drug development and manufacture of pharmaceuticals. It involves detection of the purityand toxicity of a drug substance. The present study focuses on the various steps, parameters involved inHPLC condition. It can be adopted apparently for routine quality control study of research and formulationtests. This article mainly focuses on the optimization of HPLC conditions and other important aspectsduring method of process development and validation of drug substances. The main objective of this reviewis to elaborate the novel analytical techniques utilized in method development and validation of variedpharmaceuticals because it is extremely much significant for the steadiness, efficacy and quality of thedrug product. Various validation parameters like accuracy, specificity, precision, linearity, LOD, LOQ,ruggedness, and robustness also are listed concerning ICH Guidelines. Validation is extremely much usefulfor the standard control and quality assurance of pharmaceuticals and therefore the safety of patients.
Deleted Majid Neama Ali; Ayaid Khadem Zgair
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17799

Abstract

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