cover
Contact Name
Masriadi
Contact Email
arimasriadi@gmail.com
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Unknown,
Unknown
INDONESIA
Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
The Role of Vitamin D3 as an Antioxidant and Hepatic Treatment against the Toxic Effect of Cadmium Chloride in The Rats Baraa yaqoob Al-Rahoo; Banan Rakan Dabdoub
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14839

Abstract

Current study experiments were conducted on male Rattus rattus norvigicus, at age of two months, with theweight of (200-250gm) divided into 8 groups for each group of 8 rats. The lethal average dose of (LD50) forcadmium chloride and the choice of bodyweight (5mg/kg) to inject rats Intraperitonially were determined,then orally doses of vitamin D3 after a week of CdCl2 injection at a concentration of 1000IU/kg bodyweightat three doses per week as well as for the rest of the concentrations, 2000IU/kg bodyweight, and 4000IU/kgbodyweight. After four weeks of injection and administration, blood was drawn from the rats in each group,then the rats were slaughtered and the liver was taken for tests. The current study aimed to use differentconcentrations of vitamin D3 as a treatment, the antioxidant in the liver of rats injected with heavy metalCdCl2. Due to the study, some biochemical, physiological, and tissue changes in them through the study ofliver function for rats experimenting with transactions, in addition to studying the level of oxidative stressand antioxidants in the liver. The results of the current study have shown that the role of vitamin D3 as anantioxidant and as a treatment in reducing the toxic effect of CdCl2 to a very large. The best concentration ofvitamin D3 used in the case study was 2000 IU/kg bodyweight, which was taken for rats and three doses perweek for four weeks, and after being injected with CdCl2, there was a significant decrease at the probabilitylevel P?0.05 for the concentration of the ALT when compared to the control group. On the other hand, thereis a significant rise in glutathione (GSH) and catalase (CAT) levels in rat liver, at the same concentrationof vitamin D3, when compared with the control group, while there was a clear improvement in AST andmalondialdehyde (MDA) in the liver, the results were very similar to those of the control group. Perhapsvitamin D3 dosage of cadmium-injected rats may protect improving the toxic effect of CdCl2 in the liver.
Interlukine-17 Polymorphism in Patients with Inflammatory Bowel Disease ( IBD ) in Al-Anbar Province Thikra Majid Muhammed AL-Obaidy; Hasan Ali Mutar; Thaer Abdul Qader Saleh
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14840

Abstract

Tetra amplification refractory mutation system polymerase chain reaction technique (tetra ARMS PCR)ARMS-PCR method was used to genotyping of IL-17A and IL-17F , The impact of IL-17A and IL-17Fgenotypes on the production of interleukins in IBD patients and control groups were determined andInterleukins gene polymorphisms role in IBD infection. significant deference at (p ? 0.05 ) for each rs763780in IL-17 F in patients especially Genotype TT,TC,CC were 31 (51.67%),19 (31.67%),10 (16.67%) \ andrs2275913 in IL-17 A in patients especially Genotype GG,GA,AA were 18 (30%),23 (38.33%),19 (31.67%).As well as genotyping of rs763780 in IL-17 F showed significant increase at a significant level of P?0.05in both TC and CC genotypes in the cases samples compared with the control samples. the odds ratio was2.8894 and 22.3333 for TC and CC genotypes respectively at confidence interval up to 7.8 and 397 forboth genotypes. T allele are more frequent in both cases and control and it have odds ratio as 5.021 Andgenotyping of rs2275913 in IL-17 A showed significant increase at a significant level of P?0.01 for the AAgenotyping in the cases samples compared with the control samples, while the GA genotyping did not showany significant differences, ), the odds ratio for GA genotypes was 2.3590 at confidence interval up to 5.8,while it was 8.4444 at confidence interval up to 32.9 for AA genotypes. G allele are more frequent in bothcases and control and it have odds ratio as 3.319 at confidence interval up to 6
Detection of Capsular Polysaccharide Virulence Genes rmpA and magA of Klebsiella Pneumonia Isolate from Diabetic Foot Ulcer Patient in Najaf Governorate in Iraq Ali Mohammed Hussein Al-Kamoosi; Ibtisam Habeeb AL-Azawi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14841

Abstract

Klebsiella Pneumoniae is an opportunistic pathogen, which mostly cause nosocomial infections. K.Pneumoniae utilizes a variety of virulence factors, especially capsule polysaccharide, lipopolysaccharide,fimbriae, outer membrane proteins and determinants for iron acquisition and nitrogen source utilization,for survival and immune evasion during infection. A total of (36) clinical swab specimens isolated frompatient with diabetic foot ulcer in Al-Sdder Medical City (Central Diabetic Foot) in Najaf Governorate,Iraq from November 2019 to February 2020 , for detection some virulence capsular polysaccharide genessuch as rmpA and magA that related with K1 serotype of K . pneumonia and associated with antibioticresistance pattern in patient of diabetic foot ulcer. Antibiotic susceptibility test of K. Pneumoniae isolatesagainst (20) of commonly used antibiotic showed there 25 (69%) of K. pneumonia isolate from diabeticfoot patient were Multi-drug resistance (MDR),while11(31%) were extensive-drug resistance (XDR). Theresults of amplified product demonstrated that K1 serotype of K . Pneumonia was positive in 23 (64%)of totally clinical specimen than other types of serotype ( Non-K1 serotype). (magA) gene that associatedwith hypermucoid viscosity was positive in 21 (58%) of total specimens while (rmpA) gene that regulate ofcapsular polysaccharide of K .pneumonia was positive in 22 (62%) of totally samples
Estimating the Level of Some Trace Elements in Samples of Canned Foods Spread in the Markets of Ramadi City - Western Iraq Riyadh Mohammed Jihad; Maher Ahmed Abed; Sara T. Hadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14842

Abstract

Canned food is becoming increasingly popular in the market. In order to assess the level of concentrationof some important elements in samples of these foods, ten different types of canned food were studied. Theconcentration level of nine elements (potassium, magnesium, calcium, iron, manganese, copper, zinc, leadand cadmium) was measured using atomic absorption spectroscopy. The results showed that the highestconcentrations of potassium, magnesium, zinc and lead were in the chickpeas sample. While the highestconcentration of calcium and manganese appeared in the fish sample. As for the elements of iron andcopper, the highest concentration of them was in the olive sample. In the mushroom sample, the highestconcentration of cadmium was shown.
Possible Effect of vitamin D3 on Follicular Maturation in Polycyctic Ovarian Syndrome (PCOS) Women Reyadh H. Al-Mosawi; Nuha Hamood; Huda Salim Altaee
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14844

Abstract

Polycystic ovarian syndrome (PCOS) is the most common reproductive age endocrine condition in women.Most likely, one of the major problems of PCOS patients are vitamin D3 deficiency. Therefore, investigationof the association between vitamin D3 deficiency and ovulation in PCOS women patients might help toexplore the possible relationship between them. Sixty-six patients were recruited from a private clinic inKarbala city / Al-Hindiya district, Iraq. The patients were divided into two groups (33 patients each), thefirst group treated with metformin 850 mg, b.i.d, and placebo. The second group treated with metformin 850mg, b.i.d and vitamin D3 oral supplementation 5000 IU/day for 3 months. Ultrasonography was performedmonthly on day 13 to assess the follicular size. D3 blood level was measured at the end of the 3 months.The present study demonstrated that daily D3 5000IU in PCOS women with deficient D3 whom already onscheduled metformin 850 mg b.i.d for 3 months significantly (p<0.05) increased the mid-cycle follicularsize by one 3rd in comparison to placebo group. The important finding was that vitamin D3 might enhancefollicular maturation in PCOS patients.
BOX- Genotyping of Carbapenem Resistant Acinetobacter baumannii Clinical Isolates from Diyala/Iraq Lina Abdulameer S. Alsaadi; Ibtihal Hameed Mohsin; Iman Abbas Ali
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14845

Abstract

The aim of study is to determine the typing of Carbapenem-resistant A. baumannii clinical isolates fromsome hospitals in Diyala by the BOX-PCR technique. This study was carried out during the period fromFebruary 2020 to the end of September 2020. Out of 400 specimens, 53 isolates of Acinetobacter baumanniiwere recovered. All isolates were tested toward the different class of clinically important antibiotics (12)by using agar diffusion method. The results of resistance were as following: piperacillin 53%, Ticarcillin/clavulanic acid 75%, cefotaxime 94% and ceftazidime 66%, cefepime 53%, gentamicin 84%, amikacin49%, ciprofloxacin 47%, levofloxacin 38%, Aztreonam 87%, Imipenem and Meropenem 38%. Twenty (20)isolates of Acinetobacter baumannii were found to be resistant to carbapenems. The BOX–PCR methodwas used to detect the relationship among these carbapenem resistant isolates, the fingerprinting patterns ofthe isolates were shown 15 bands on gel electrophoresis, with molecular weight ranging between (100-3000bp) among the 20 carbapenem resistant Acinetobacter baumannii isolates. Genetic relationship of differentisolates of Acinetobacter baumannii was done by using BOX-PCR method and Dendogram analysis.The results showed the genetic relationship between Acinetobacter baumannii 4 clones, while 12 isolatescontained different genotyping. In conclusion, the present study showed that the BOX-PCR technique isreproducible, easy, fast and cost effectiveness tool for investigating the genetic diversity of A. baumanniiisolates.
Investigation of Some Trace Elements levels & Antioxidants in Patients with Thalassemia Major and Sickle Cell AnemiaThalassemia in South of Iraq Qais R. Lahhob; Nidhal Y. Mohammed; Hamid J. Abbas
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14846

Abstract

Back ground: Thalassemia major) THM( is the most common single gene disorder. It is a hereditary blooddisease characterized by reduced or absent production of beta globin chains. For the patients with SCA-Thal,they have two mutations (sickle cell anemia and thalassemia). The ratio of minerals and trace elements in thepatients’ blood played an important role in many biological processes. This study aims to measure the levelof seven elements, Fe, Mn, Ca+2, Mg, P, Cr, Co and three another antioxidant element (Zn, Cu &Se) in theblood of THM and SAC-thal patients.Results: In THM and SCA-Thal patients, antioxidant elements (Cu, Zn & Se), showed highly significantbehaviour when compared to each other and with the control group as total patient population, and as (total,male and female) numbers. In thalassemia patients, Fe, P & Co also showed highly significant behaviour,while Ca + 2 behaviour was not significant for male numbers only. Elemental Mg & Cr, demonstratedinsignificant behaviours. In SCA-Thal patients, Mn & Ca + 2 showed highly significant behaviour, while,Fe showed a non-significant behaviour relative to male numbers only, and Mg, P, Cr & Co showed nonsignificant behaviour.Conclusion: The study revealed the similarity of antioxidant elements behaviour in both diseases, as well asthe statistical behaviour of all elements when compared with the control group for these diseases.
The Influence of Booklets and Videos on the Ability to Practice Breast Self Examination in Students of High School 4 Gorontalo Nancy Olii; Nurnaningsih Ali Abdul
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14847

Abstract

Individual awareness in taking actions properly BSE is influenced by the individual understanding ofbreast cancer, so health promotion Efforts are Necessary. Videos and booklets are some alternative healthpromotion media. The research objective was to determine the effect of booklets and videos on the abilityto practice breast self-examination on students at High school 4 Gorontalo . The research used the PreExperiment method with a one-group pretest-posttest design, Carried out in August-October 2019 at Highschool 4 Gorontalo . The research sample was 60 female students from a population of 119 students usingthe purposive sampling technique. Statistical test using Paired t-test. The results of the analysis of thedifferent test on the ability of Breast Self Examination (BSE) before and after reading the booklet showedthat there was a difference in BSE ability with p-value = 0.001, while before and after watching the videoshowed that there was a difference in BSE ability with p = 0.001 (p <0.05). This study concluded that therewas an increase in the students’ BSE practice skills after reading booklets and watching BSE videos atHigh School 4 Gorontalo. It is hoped that students can increase their knowledge and apply BSE so that theincidence of breast cancer or breast disorders can be prevented and detected early.
Preparation, Characterization, Antibacterial Study, Toxicity Study of New Phenylene diamine- Formazan Derivatives Hussein Ali Ahmed; Nagham Mahmood Aljamali
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14848

Abstract

Formazans are known to be characterized by containing very effective functional groups that have an effecton the possession of any compound with a pharmaceutical and biological characteristic as antimicrobialsfor many microbes, as these compounds have proven high resistance to the spread of cancerous tumors andthe spread of bacteria and fungi. Series of formazan derivatives were synthesized in this study from metaphenylene diamine via imination reaction then coupling reaction to yield new five derivatives. The formattedformazan derivatives have been investigated through various instrumental -spectral techniques representedby (I.R- Infrared spectra ,H. NMR -Proton magnetic resonance , Mass -Spectra )– as a spectrophotometricmeasurements ,then bio- studying via various bio- experiments in this field like cytotoxicity, resistance ofanti-bacteria.
Patellar Anthropometry in Sex Differentiation - A Study in the Southern Part of Andhra Pradesh, India Nagarjuna K; Mamatha K; Venkateswarlu B
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14849

Abstract

As in many cases, long bones get available in fragments, so gender determination from short as well asrobust bones like patella is paid importance nowadays. So far, the literature reviewed show such records arefound little in India, especially from the state of Andhra Pradesh. The present study is aimed to demonstratethe gender differentiability of different patellar anthropometric parameters viz, length, breadth, weight,thickness & patellar Index, etc., amongst the population of the southern part of Andhra Pradesh in India.A total of 50 intact patellae of which 25 belonging to males and 25 belonging to females, were takenout from human corpses of 20 to 50 years of age group, brought for postmortem to the Department ofForensic Medicine, Sri Venkateswara Medical College, Tirupati. Patellar vertical length, width, differentmeasurements of the individual articular facet, patellar index, and surface area of the articular part, etc.,were measured. In males, the mean of patellar length, Patellar index, Dry weight, Articular surface area werefound to be 3.892 cm, 115.36, 20.06 gm, and 14.164 cm2 respectively and in females, the mean of patellarlength, Patellar index, Dry weight, Articular surface area were found to be 3.608 cm, 103.12, 15.16 gm and9.664 cm2 respectively. The values are found to be less in females than those found in males. The results ofthis study revealed that we can determine the sex of the southern Andhra Pradesh population, just by usingthe patellar measurements when other long bones, skull, and pelvis are not available or fragmented. Butthere remains scope for multicenter study throughout India to validate the fact.