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<![CDATA[Disclosure of Confidential Medical Record of The Patient of Corona Virus Disease 2019 ]]>
<![CDATA[Mokhamad Khoirul Huda]]>;
<![CDATA[Yulianto]]>;
<![CDATA[Ninis Nugraheni]]>;
<![CDATA[Yoan Nursari Simanjuntak]]>;
<![CDATA[Sadjijono]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14815
<![CDATA[This study aimed to find out the disclosure of confidential medical record of Covid-19 patients from legalnorms, ethics and medical disciplines in Indonesia. This research used normative juridical methods whichhad a pre-descriptive characteristic.This research found the disclosure of confidential medical record ofthe Covid-2019 patients can be opened for the benefit of the patient’s health, fulfilling the demands of lawenforcement officials in the context of law enforcement, the patient’s own request, or based on statutoryprovisions.This research is very useful for the community, hospitals, educational institutions and thegovernment to provide legal protection to society to not be exposed by Covid-2019. The disclosure ofconfidential medical record of Covid-19 patients is permitted in relation to the patient’s initials, gender,place of residence, age and health status.]]>
<![CDATA[Comparative Evaluation of Expression of Markers of Proliferation, Angiogenesis, & Apoptosis in OSMF before and after treatment with Polyherbal Preparation – Study protocol ]]>
<![CDATA[Mrunal G. Meshram]]>;
<![CDATA[Vidya K. Lohe]]>;
<![CDATA[Rahul R. Bhowate]]>;
<![CDATA[Bhushan S. Madke]]>;
<![CDATA[Ravikant V.Sune]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14816
<![CDATA[India alone accounts for one third of the world’s oral cancer and has a high rate of Oral Potentially MalignantDiseases (OPMD) amongst Areca Nut & Tobacco Habitual. Oral submucous fibrosis (OSMF) is one ofthe OPMDs which predominantly affect major population of South and Southeast Asia, especially Indiansubcontinent. Till date OSMF patients are treated symptomatically to relieve burning sensation, improve theopening of mouth & tongue movements, reduce blanching and relieve from roughness of oral mucosa byusing various medicinal line of treatment i.e. vitamin A, lycopene, beta carotene and carotene analogs, but notreatment is directed towards the reduction of malignant potential of preexisting OSMF cases. Thus, presentstudy will be conducted to compare the pre & post treatment serum level of proliferation, angiogenesis andapoptosis inducing expression of markers with polyherbal therapy in oral submucous fibrosis. Methods:Identification of clinically diagnosed patients of OSMF who will be divided into two groups by simplerandom sampling procedure. Group-1 patients suffering from oral submucous fibrosis, will be receivingPolyherbal Preparation while Group-2 patients receiving Lycopene. Pre and post treatment comparison forclinical signs and symptoms and serum marker expressions for Proliferation, Angiogenesis, & Apoptosis inboth groups will be done and statistically analyzed. Results: Clinical signs and symptoms will be improvedwith the present polyherbal protocol. Post treatment serum marker may favored reduction in proliferation,angiogenesis and induced apoptosis which predicts malignant transformation. Conclusions: Polyherbaltherapy will help to reduce the malignant conversion without toxic effect on other system of the human body]]>
<![CDATA[Polydioxanone Sutures Instead of Polypropylene Sutures for Abdominal Closure to Prevent Wound Sinuses ]]>
<![CDATA[Muhammad Albahadili]]>;
<![CDATA[Mohammed Jabbar Kadhem]]>;
<![CDATA[Ammar Wadood Majeed]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14817
<![CDATA[Abdominal closure after laparotomy takes several weeks to get 80% of its previous strength in this periodthe fascial sheath should be hold by sutures. Several materials used in the abdominal closures but the mostcommon suture used is polypropylene, others used nylon, less common used is absorbable sutures but woundsinus is a complication may fellow the use of non-absorbable sutures. For two years we collect 235 patientsin all of them abdominal wall incision was Pfannenstiel, in 133 patients the incision closed by polypropylene(non-absorbable), for other 102 patients the incision closed by polydioxanone (slow absorbable) the resultwas significant for wound sinus formation in polypropylene group but insignificant for hernia, conclusionof the study the polydioxanone look the same strength of polypropylene and may be without wound sinusformation.]]>
<![CDATA[The Modification of Workstation of Lipa Sabbe Weavers as an Effort to Reduce Musculoskeletal Disorders (MSDs) ]]>
<![CDATA[Muhammad Azrul Syamsul]]>;
<![CDATA[Helmy Gani]]>;
<![CDATA[Rizky Maharja]]>;
<![CDATA[Arni Julian]]>;
<![CDATA[Andi Tenriola Fittri Kessi]]>;
<![CDATA[Sitti Fatimah Rahmansyah]]>;
<![CDATA[Habibi]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14818
<![CDATA[Work with more loads and equipment design that is not ergonomic results in the use of more energy and riskywork postures. Working in a sitting position basically can reduce stress on the feet, energy consumption,and circulation requirements. Ergonomic workstation is an example of the application of ergonomics whichaims to create a balance between various aspects of each work system and process carried out as an attemptto create a high quality of work and quality of life, as well as an effort to prevent occupational injuries anddiseases. This study aimed at modifying the workstation to reduce MSDs among lipa sabbe weavers. Thisis a quasi-experimental study with one-group pretest-posttest approach to analyze differences in the levelsof MSDs before and after the intervention through modification of ergonomic workstation designs. Theparticipant selection technique used purposive sampling. The research instruments used were Nordic BodyMap questionnaire, camera, and anthropometric measurement tools. Data were analyzed using WilcoxonSigned-Rank Test. The result showed that there is a difference in the level of complaints after modificationof the work media of lipa sabbe weavers. It indicates that modification of work media can reduce MSDsamong lipa sabbe weavers.]]>
<![CDATA[Images of Ultrasonography or Abdominal Computed Tomography Scanning in Cases of Malignant Kidney Tumors ]]>
<![CDATA[Muhammad Hidayat Surya Atmaja]]>;
<![CDATA[Bambang Soeprijanto]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14819
<![CDATA[Background: The malignant kidney tumor is a urinary tract tumor with the highest mortality and morbiditycompared to other urinary tract tumors. The role of USG radiology and CT scan is essential for diagnosingmalignant kidney tumors.Objective: To examine the diagnostic value of USG radiology and CT scan in diagnosing malignancy ofkidney tumor and its accuracy in assessing renal tumor operability.Methods: This study was a retrospective observational study using secondary data of radiologicalexamination including ultrasonography, CT scan and other postoperative results derived from medicalrecords. Data analysis was conducted descriptively.Results: The sensitivity score of USG, CT scan, and USG and CT scan was 60%, 82%, and 83% respectively.Sensitivity value of ultrasound examination was 60% and CT Scan was 82%. The incompatibility ofultrasound with pathology results was found in the case of hydronephrosis with the stone of 64%, stone of18%, cyst of 18 %, on CT Scan hydronephrosis with stone (83%) Pyelonephritis (17%). The incompatibilityof USG and CT Scan with operating results was 8%.Conclusion: Incompatibility of USG results with anatomic pathology results was found in cases ofhydronephrosis accompanied by stones, kidney stones, and benign lesions (cysts). Incompatibility of CTScan results with anatomic pathology results was found in cases of hydronephrosis accompanied by stoneand pyelonephritis.]]>
<![CDATA[Fibroblast Growth Factor 23 in Children with Chronic Kidney Disease ]]>
<![CDATA[Muhammad Riza Kurniawan]]>;
<![CDATA[Risky Vitria Prasetyo]]>;
<![CDATA[Ninik Asmaningsih Soemyarso]]>;
<![CDATA[Mohammad Sjaifullah Noer]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14821
<![CDATA[Background: Decreased of glomerular filtration rate in chronic kidney disease (CKD) changes the calciumand phosphate balance. High phosphate levels in children with CKD stimulate secretion of FibroblastGrowth Factor 23 (FGF23). High FGF23 levels have harmful that potentially increase the morbidity andmortality of children with CKD.Objective: To analyze the level of FGF23 in children with CKD.Methods: A cross sectional study was performed in Pediatric Nephrology Ward and Outpatient Clinic ofDr. Soetomo General Hospital Surabaya, during December 2019-March 2020 for children with CKD stage1-5, aged 3 months to 18 years old. Children on phosphate-binder, vitamin D therapy, or severely ill wereexcluded. Blood level of FGF23 was measured using ELISA with statistic analysis with SPSS 20.Results: A total of 52 CKD stage 1-5 children were involved, mean age was 11.44 years old, and 50% wereboys. There were 51% children have FGF23 level more than 30 pg/ml. The lowest mean of FGF23 levelswas found in the CKD grade 1 (8.94 ± 8.77 pg/mL) and the highest mean at CKD grade 5 (113.30 ± 78.73pg/mL).Conclusion: The FGF23 level increasing accordance with increasing in the grade of CKD]]>
<![CDATA[The Prevalence and Risk Factors of Tracheostomal Stenosis Following Total Laryngectomy ]]>
<![CDATA[Muhtarum Yusuf]]>;
<![CDATA[Sofia Tiarini]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14822
<![CDATA[Background: Tracheostomal stenosis (TS) following total laryngectomy is relatively common in patientsand a distressing complication with major effects on patient rehabilitation it affected 4-44% of patientsfollowing total laryngectomy worldwide. Various etiological factors and some risks have been indicated ascontributing to the onset of stenosis.Purpose: We aimed to investigate the prevalence and risk factors of tracheostomy stenosis following totallaryngectomyMethod: Tracheostomal stenosis was defined as respiratory insufficiency at rest or during exercise, difficultyin tracheal clearance due to non laminar flow, or both. Eighty data of patients were enrolled in this studyconsisting of 76 male (95.0%) and 4 females (5.0%). Baseline characteristics (BL) stage of cancer (SC), typeof surgery (TS), the onset of stenosis following surgery (OS) and risk factors (RF) from each patient wererecorded and analyzed using a pre-installed statistic software.Result: The overall prevalence of tracheostomal stenosis was 13.8% (11 of 80 patients). The prevalence andrisk factors of tracheostomal stenosis following total laryngectomy consisted of 7 hypertrophic scar patients(63.3%), 2 infection patients (18.12), and 1 radiotherapy and peristomal fat patient (9.01), respectively.Conclusion: Out of eighty patients, eleven patients indicates the characters of tracheostomal stenosisusing the bevel technique. The most common etiological factor is hypertrophic scar, followed by infection,radiotherapy and peristomal fat.]]>
<![CDATA[Hormonal Receptors and Human Epidermal Growth Factor Receptor 2 Discordance between Primary and Recurrent Breast Cancer in Sample of Iraqi Patients ]]>
<![CDATA[Muna K. Zaweer]]>;
<![CDATA[Azhar S. Alzubaidi]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14823
<![CDATA[Background: Though progesterone receptor and estrogen receptor are weak prognostic indicators,they are greatly predictive of response to endocrine therapy. HER2 overexpression or amplification is apowerful predictive factor for response to specific systemic therapies. Variation in estrogen receptor (ER),progesterone receptor (PR), and HER2 status between primary breast carcinoma and subsequent relapse ofis clearly recognized. Aim of study: The study aims at determining the rate of discordance in progesteronereceptor, estrogen receptor and human epidermal growth factor receptor 2 status between primary tumor andsubsequent locoregional and metastatic disease in a sample of patients attend oncology teaching hospital.Patients and Methods: A retrospective study conducted included 80 females patients attending oncologyteaching hospital between December 2013 – December 2017 for whom the ER,PR,and HER2 status wereknown on tissue samples of both primary and subsequent locoregional and metastatic disease .Results: The ER,PR,and HER2 status discordance rate for between primary breast cancer and subsequentlocoregional relapse and distant metastasis was 27.5%, 42.5% and 22.5% respectivelyConclusion: The rate of discordance in ER and PR status primary and relapsed breast carcinoma in patientsmanaged at oncology teaching hospital was similar to other studies. While the rate of discordance for HER2status between primary and relapsed breast carcinoma was slightly higher than international studies.]]>
<![CDATA[Screening of Group of Iraqi Patients with Turner’s Syndrome in Relation to Karyotype-Phenotype Variation ]]>
<![CDATA[Muneera Fadhil Ridha]]>;
<![CDATA[Amenah Fadhil Ridha]]>;
<![CDATA[Ruqayah Gheyath yaseen]]>;
<![CDATA[Ahmed Kamal Kasim]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14825
<![CDATA[Background: There is variation in karyotype that can be related with the phenotype difference in patientswith Turner syndrome (TS).Objective: Asses the relationship between karyotype and phenotype of confirmed Turner Syndrome patientsand Screening them for related congenital and immunological conditions.Methods: Eighty-five cases of TS were comprised. Patients were indicated mainly for evaluation of shortstature and (or) delayed puberty; Standard karyotyping was analyzed on the basis of routine G-bandingtechnique. Turner’s syndrome is divided into traditional and non-traditional with further categorization withrespect to Karyotype. After full examination, screening tests comprising thyroid function tests, celiac screen,Echocardiography, Renal and pelvic ultrasonography was achieved.Results: Webbed neck and Dysmorphic facial characteristics were more found during clinical examinationin traditional TS versus Non-traditional Turner’s syndrome with p-value of 0.01 and0.027, respectively.Abnormal thyroid function tests were more common in traditional TS than Non-traditional, p-value 0.02.Abnormal findings (mainly streak ovary) on pelvic ultrasound (US) was also more common in traditionalTS than Non-traditional, p-value 0.01.Conclusion: Screening of patients with Turner’s syndrome with respect to phenotype -karyotype differencecan provide opportunities for enhancement of our knowledge, diagnosis and further management.]]>
<![CDATA[Pharmacokinetic Parameters of Meropenem in the Plasma and Milk of Ewes ]]>
<![CDATA[Mustafa Ahmed Jasim Al-Jumaili]]>;
<![CDATA[Orooba Mohammed Saeed Ibrahim]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v15i2.14826
<![CDATA[This study had been designed to evaluate the pharmacokinetic parameters of Meropenem in plasma andmilk of ewes after intravenous bolus adminsteration, for this purpose, five healthy miking ewes had beenreceived a single intravenous bolus of Meropenem (20 mg/kg) to characterize both of distribution andelimination of Meropenem in plasma and milk, concentrations of Meropenem in plasma and milk hadbeen analyzed by microbiological method and pharmacokinetic data had been analyzed by compartmentaland noncompartmental methods, results of mean ± standard deviation for half-life, volume of distributionand total body clearance for plasma samples were 0.67 ± 0.09 h., 0.169 ± 0.01 and 0.3 ± 0.02 L/hr/kg,respectively, the plasma protein binding ratio were 7.27 ± 0.22 %; while the half-life, Cmax and drugpenetration ratio for milk samples were 9.56 ± 3.13 h, 3.91 ± 0.99 ?g/ml and 0.86 ± 0.23 respectively. Inour conclusions; Depending on the approval state of Meropenem for veterinary therapy, we think that theachieved pharmacokinetic parameters of Meropenem in plasma and milk of ewes will candidate it to be oneof the preferred parentrally administered antibacterial agents to encounter the acute cases of mastitis thatought to be treated hastily.]]>
