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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
A Therapeutic Action of Vatari Guggulu in Amavata, Sandhigata Vata & Grudhrasi Geeta Vishwanath Sathavane; Shilpa Gabhane; Madhulika Tiwari; Komal Kedar; Seema Thakre; Shailesh Nagpure
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15057

Abstract

Drug (Ausadha) is a part of quadruped of the treatment, which has been placed next to the physician. Thecomprehensive knowledge of the drug is very important to physician because without knowledge of drugpatient cannot be treated properly. Vatari guggulu is such herbal remedy mentioned in the ancient ayurvedictexts of Bhaishajya Ratnavali Amavata chikitsa prakarana for the treatment of various diseases like Samavata,Katishool (Low back ache), Grudhrasi (Sciatica), Khanja, Pangu, Vatarakta (Gout) ,Shotha, Daha ( Relivesburning sensation) and Koshtukshirsha. It having Vatashamaka, Kaphashamaka, Aamapachana, dipana,Vedanasthapana and Rasayana properties. Various study is carried out to evaluate the efficacy of drug VatariGuggulu in diseases like Amavata,Sandhigata Vata and Grudhrasi and significant results were obtained.Thepresent review article aim to evaluate the Theurapeutic action of Vatari Guggulu in aamavata,SandhigataVata,Grudhrasi.
Clinical Assessment of a Local Application of Kasisadi Ghrita in Parikartika (Fissure-in-ano) Snehal Kukade; Mamata Mate; Komal Kedar; Seema Thakre; Shailesh Nagpure
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15058

Abstract

Background: Parikartika is charecterised by sharp cutting pain in anal region. In Parikartika Teevrashoola,bleeding is observed, equally extreme pain& slimy blood discharge are seen in Fissure-in-anoObjective: To test the efficacy of thelocal application of Kasisadi Ghruta in managingMethods: Classical signs and symptoms ofParikartika (fissure inAno) Age groups of 20 to 60 years havebeen recruited for the researchThe trial group obtained treatment with Kasisadi Ghruta local application for28 days, twice a day.Results: Average relief observed was observed 62.5% for most symptoms Shothahara, Vedanasthapana andRopana are in Kasisadi Ghruta. Properties because of which it helps in healing the ano fissureConclusion: Local Kasisadi Ghruta The programme has better results in the Fissure in ano.
Genetic Polymorphisms of the Efflux Transporter Gene ABCB1 and Their Effects on the Anastrozole Response in Iraqi Breast Cancer Patients Hiba Salah Mahdi; Ahmed Salih Sahib; Hassan Mahmood Mousa Abo Almaali; Karrar Kadhim Mohsin
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15059

Abstract

Background: The ABCB1 gene (ATP-binding cassette) encodes the ABCB1 transporter. Anastrozole is asubstrate for the ABCB1 efflux transporter. The objective of the study was to detect the genetic polymorphismsof this efflux transporter in Iraqi breast cancer patients and their effects on the anastrozole response.Method: Blood samples were taken from breast cancer patients, and a portion of each sample was used forbiochemical analysis (measuring estradiol and cancer antigen 15.3 levels), while the remaining portion wasused for genetic analysis. Genotyping demonstrates that the mutant genotype being the most frequent typefor both C1236T and C3435T SNPs.Results: The result indicated nonsignificant differences in the serum levels of estradiol or cancer antigen15.3 among different genotype groups of the ABCB1 gene.Conclusion: It is concluded that the ABCB1 gene is highly polymorphic in Iraqi women with breast cancer.This study indicated that ABCB1 gene may not affect the response to anastrozole.
Clinical important of E-Cadherin, CA15-3 and CEA in Diagnostic and Flow Up for Breast Cancer Patients Alaa Haleem Imran; Sahib Ali Al-atrachji; Karar Kadhim Al-mosawi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15060

Abstract

Background: The normal prevailing cancer in the women is Breast cancer, other than nonmelanoma skincancer. E-cadherin performs an essential role in epithelial cell adhesion and the decline of its role is the maindonor to cancer rise because the majority of solid tumors are carcinomas that occur from epithelial tissue. Asegment of the mucin-1 (MUC-1) is the cancer antigen 15-3 (CA15-3) order of glycoproteins, is classifiedas a serviceable tumor marker inspired by revised glycosylation of itself. The carcinoembryonic antigen(CEA) levels is raise in the blood, as a sort of cell adhesion molecule are associated with tumor metastasis.Methods A cross-sectional study held implemented on100 specimens, 50 patient with breast cancer ere andsubsequent chemotherapy therapy with 50 healthy individuals (healthy patients).Results The result reveals significant disparities patient group the same patient as a novel cause, followinginitial chemotherapy procedure and matched with the control group in some tumors markers such as (CA15-3, CEA) exact (E-cadherin) shows non-significant.Conclusions Our cross-sectional study designates that the E-Cadherin was non-significant for breast cancerpatients including Tumors markers (CA15-3, CEA) bestows significance with breast cancer patients.
Microsafe (Oral Care) to Control COVID-19 Infection Muamer Alshalah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15061

Abstract

Dental practice poses a possible risk of cross-infection with COVID-19 among patients, dentists, and theirassistants by direct saliva exposure and indirect contact. At Al-Kafeel Hospital in Karbala, Iraq, This studyhas focused on using Microsafe (Oral car) as a mouthwash product to COVID-19 control infection.Materials and Methods: One hundred people used the Microsafe (oral care) as a mouthwash productto prevent COVID-19 for two months. Fifty persons from Al-Kafeel Hospital staff (dentists) are fullycommitted to prevention measures, and fifty persons from the Al-Kafeel Hospital patients regularly attendhospital treatment. Not all patients can be guaranteed and apply these preventive measures.Results: After two months of using Microsafe (oral care) as a mouthwash, only eleven of the total patientswere affected with COVID-19. Only three of the hospital staff and eight patients were affected.
The Impact of Antioxidants in Blood Pressure and Free Radicals of Athletes Mohammed Nader Shalaby; Sherin Hussien; Mona Mostafa Abdo Sakoury; Adel Mohamed Mohamed Atiaa; Mohamed Abdalla Antar Galila
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15062

Abstract

Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogenspecies and the lack of protective ability in antioxidants. From that point of view, free radical-induceddamage caused by oxidative stress seems to be a probable contributing factor to the pathogenesis of manynewborn diseases, such as respiratory distress syndrome, bronchopulmonary dysplasia, periventricularleukomalacia, necrotizing enterocolitis, patent ductus arteriosus, and retinopathy of prematurity. This studywas conducted on a sample of (30) players. researchers used the experimental approach (equivalent groupsfor its suitability and method of study. the sample was divided into two groups, (15) players representingthe control group and (15) players representing the experimental group. the study aims to identify theeffect of antioxidants on oxygenated blood pressure and free radicals for athletes. the study showed thatthere is an effect of antioxidants (vitamins on increasing the activity of the enzyme (SGOT) involved inATP rebuilding processes, and an effect of antioxidants on reducing oxygen blood pressure while not theeffect of antioxidants on SGPT enzyme activity is clear, which shows that it is not involved in reducing freeradical, muscle fatigue and blood pressure. Hence, the researchers came out with a set of recommendations,including the need to pay attention to taking vitamins because of their role in reducing the effects of freeradicals and emphasizing the gradual increase in training loads.
A Study to Assess Awareness Levels and Status of Lipid Parameters in the Subjects with Coronary Artery Disease in Tertiary Care Setup in a Rural Area DVSS Ramavataram; Prasad Snehita; Tejas Shah; Sheetal Chhaya; Mishra Mritunjay
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15063

Abstract

Background:-. Among the various cardiovascular diseases, Coronary artery disease is one of the majoretiology of mortality and morbidity in the world wide population. It is a prevalence in mainly older adultsand exists in the entire health context. The CAD prevalence was strongly associated with various lipidparameters such as cholesterol and different lipoprotein fraction, which contributed as a major factor for theprogression of CAD. In spite of various therapeutic advances, so for safe and effective management of CAD,there are requirements for consideration of risk/benefits and goals of care.Objective: To determine the current level of knowledge of the symptoms and duration of diseases and alsocomparison of lipid parameters in cases and control.Material and Methods:-The study was a case control observational study conducted in the department ofbiochemistry, SBKSMI& RC. A total of 200 subjects of 100 Coronary artery disease (CAD) and 100 healthycontrol were enrolled to assess lipid parameter and duration of diseases.Result: - There were 82% male and 18% female in case group and CAD caused majorly by the anginawhich was 65% and in the symptom of duration, majority of people aware with their symptoms in less than1 months. In the measurement of dyslipidemia there was significantly higher in atherogenic component i.e.LDL-C and anti atherogenic component i.e. HDL-C was also higher and found significant.Conclusion: - The majority of subjects who were suffering from CAD were males compared to females.Most of the patients from a rural areas so they had a chest pain comparison to heart attack and found highlysignificant with lipid parameters.
A Study to Assess the Knowledge on Food Practices among Postnatal Mothers Kavita J. Gomase; Ribeka P James
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15064

Abstract

Introduction: Women need to receive special health and social support during postnatal time to preventproblems. Inadequate care might result in complications for the mother and her child. Nutrition plays animportant role in the course of the postpartum period. It is well documented that dietary modification duringthis period has a profound effect on the nutritional status of both the mother and the newborn. According torecent studies, Sueel Raj and Mishra (2008) examined the food consumption pattern and associated habitsof the Bhil tribe of Dhar district of Madhya Pradesh. They found that no special foods are being consumedduring pregnancy. Sahoo and Panda (2005) while studying in the Balasore District of Odisha found thatsome sort of food restrictions during pregnancy. The general concept was that the restricted food itemswould cause cold and cough to the mother or would lead to abortion. Aim: To assess the knowledge on foodpractice among postnatal mothers. Materials and Methods: A descriptive survey research design was donefrom March 2019 - July 2019 in 30 postnatal mothers. Data was collected with structured questionnaire onknowledge on food practices among postnatal mothers. Questions are How much kcal required for PNCmother. Green vegetables helps in, Dairy product helps in, Protein helps in..etc. Descriptive statistics wererepresented in Frequency and percentage. Statistical tests used were One way ANOVA test and independentT –test and Chi square test. The level of significance was considered to be statistically significant whenthe p-value was ?0.05. Result: Distribution of postnatal mothers according to their age in years shows themajority (76%) of them belongs to the age of 20-30 years, Distribution of postnatal mothers according totypes of diet that majority of (73%) have vegetarian, 20%non vegetarian, 6% have taking mix diet. Themajority 16 (53%) women were having average level of knowledge , 14(46%) women were having goodlevel of knowledge .The minimum score was 4 and maximum score was 11, , the mean score was 7.80 andstandard deviation is 2.18 respectively Conclusion: This reveals that age group of 20-30years have moreknowledge, 16 (53%) women were having average level of knowledge , 14(46%) women were having goodlevel of knowledge
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Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15080

Abstract

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Study of Acute Renal Failure in Anemic Patients at Vidharbha Region Gangaram Bhadarge; Pradip Jain; Neha Bhatt; Archana Dhok
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15081

Abstract

Introduction: Anemia is commonly characterised as haemoglobin in men of less than 13.0 g/dL andin premenopausal women of less than 12.0 g/dL. Chronic kidney disease (CKD) anaemia is a type ofnormocytic normochromic hypo-proliferative anaemia. It is also associated with poor results in CKD andraises mortality among other CKD complications. After a greater than 50 percent loss of kidney function,the disease normally begins to progress, generally when the glomerular filtration rate (GFR) falls to lessthan 60 mL/min. When chronic kidney disease (CKD) progresses, the seriousness of anaemia continues toworsen. Erythropoietin deficiency in renal development and the incidence of anaemia do not always appearto correlate with renal impairment severity.Material and Methods: Total 60 patients of iron deficiency anemia were taken for the study which contains55% (33) male patients and 45% (27) of female patients. This is a cross-sectional investigation whereincases were out-patients. Patients went to the Directly Observed Treatment Short-course focus in the Dept. ofGeneral Medicine. The samples were used to analyze serum urea, Creatinine and Hematocrit value.Result: The level of urea in male (260.69±38.25) is non-significantly high than in female (241.0±34.16)patients.The hematocrit value was significantly low in both men and women (p=0.0006) indicating nodifference irrespective of gender. However, it was discovered that the mean value of females (20.14±2.63)was higher than that of males (17.90 ±2.16).Conclusion: Our study concluded that hematocrit value had a strong association with acute renal failureirrespective of the gender and the severity of the anemia is independent of the maximum or minimum valueof the creatinine or urea.