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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Physiological and Molecular Study for Some Cases of Coronary Artery Disease Zahraa Abdali Mohammad; Ali MHussein; Hassan R Mobarek
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16000

Abstract

Coronary artery diseases (CAD) known as the disorders of the heart and the blood vessels, which claimed 17.1 million lives a year worldwide. to identify the correlation between the coronary artery disease and some physiological and molecular parameters in men. one hundred blood samples (5 ml) collected from coronary artery diseases patients, the Complete blood count parameters (CBC), Serum concentrations of Creatinine, Glucose, Cholesterol, Triglycerides, HDLLDL, T3 , T4 and TSH were measured in current study. Multiplex polymerase chain reaction used to determine the presence or absence of GSTM1 and GSTT1 genes in the genomic DNA and CYP1A1 as an internal control. The results of current study showed significant increase in the total WBC, Neutrophil, Lymphocyte, MCH, MCHC,PLT, MPV, PCT, creatinine, glucose, cholesterol, Triglyceride, LDL andTSH in patients group when compared with control.The percentage of coronary artery diseases were increase 47% when the GSTM1 gene absence in patients group compared with control,while no significant differences were recorded when GSTT1 gene absence and the two genes absence in patient group compared with control.The study concluded that physiological indicators may increase in patients with Coronary artery diseases .
The Effect of Combination of Turmeric and Black Pepper Extracts in Osteoarthritis of the Knee Zahraa Matheel Nasir; Haidar M. Jawad; Sami S. Salman
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16001

Abstract

The management of osteoarthritis (OA) remains a challenge. Curcumin is basically a spice that is known for its anti-inflammatory properties. In vitro studies suggest that curcumin could be beneficial for cartilage in OA. Piperine, derived from black pepper, is added to Curcumin to increase its bioavailability. The aim of this randomized, double blind trial was to evaluate the effects of combination curcumin plus piperine in knee OA patients.A total of 43patients were randomly assigned to receive the fixed dose combination (curcumin 500 mg plus piperine 5 mg) or placebo twice daily for three months and was evaluated using a Western Ontario MacMaster (WOMAC) score. Results revealed the serum levels of High Sensitivity C - reactive protein (HS-CRP)and Human Cross Linked C-Telopeptide of Type II Collagen (CTX-II) were changedafter 3 months of treatment. In conclusions: The treatment with curcumin was globally well tolerated. It significantly decreased the WOMAC score and NSAIDS uses. Serum level of CTXII significantly reduced (p<0.001) and tended to decrease serum HS-CRP. In addition, curcumin significantly reduced body mass index,this may point toward that curcuminoids has role in weight reduction,and hence, lower risk of OA
A Comparative Study between Rosuvastatin and NanoRosuvastatin Effects on Liver in Mice that Consuming Diets Rich in Vegetable Oil Zahraa Saad Hussain; Jasem Hanoon Hashim Al-Awadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16002

Abstract

The study was designed to evaluate the histological changes occurring in mice liver subjected to a highfat diet for 4 months, and to assess the effectiveness of Rosuvastatin drug in its two forms (free and nano) in alleviating these changes. Consumption of a high-fat diet (vegetable oil) resulted in mild to severe lymphocytes infiltration, sever lipid accumulation as macro and microvesicularsteatosis, necrosis, pyknotic nuclei. The histology of liver sectionsobtained from mice treated with rosuvastatin showed lower severity in comparing with positive control mice. Histological changes include infiltrated lymphocytes, pyknotic nuclei, apoptotic cells. Furthermore,Liver sections from the Rosuvastatin treatment group showed ameliorated steatosis when comparedto a high-fat diet treated group. Liver sectionsof thenanoRosuvastatintreated group showed much more improvement comparedtoRosuvastatin treated group.
A Survey to Assess Clinical Pharmacy Services in Makkah County Hospitals, Saudi Arabia Yosra Al-hindi; Sahar El-ashmony
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16003

Abstract

Background:The services of clinical pharmacy is not included for science purposes only;it includes wide variety of public care and patient engagements. Makkah is a holy city in a developing country which indeed can improve their clinical pharmacy services perspectives.Objectives:Our main objectives were appraising therule of clinical pharmacy services in Makkah. Materials: This was done bysurvey questionsfor clinical pharmacists in Makkah county hospitals.Results: Our data showed that most coverage of clinical pharmacy services on both the scale ofdepartment is 17.14 percent and the scale of patients is 13.2 percent, that means the service does not cover the exact rule of clinical pharmacists. About 57.7 percent of the county hospitals, the pharmacists did not meet the requirement, and the numberwas smaller than in other hospitals.Conclusion:Our data showed that there is a very small percentage of the services of clinical pharmacy as well as the software, hardware.Moreover, there was a huge gap in the teaching methods.
Microplastic Contents in Kijing Shells (Pilsbryoconchaexilis) in Tallo Makassarriver, Indonesia Yuliati; Anwar Daud; Anwar Mallongi; Burhanuddin Bahar; Mukono; Mahatma Lamuru; Maming
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16005

Abstract

Background : Plastic pollution in the aquatic environment has become a global concern because of its detrimental impact on river and marine ecosystems. Plastic waste that breaks down into plastic particles of microplastic size (less than 5 mm), allows fine particles to enter the food chain and leads to humans as top predators in the food chain.The purpose of this study was to determine the microplastic content of Kijing Shells (Pilsbryoconchaexilis) in the Tallo Makassar River.Methods: This type of research is observational with a laboratory approach using Minitab 16 software to determine the microplastic content of Kijing Shell (Pilsbryoconchaexilis) in the Tallo Makassar River.Results: The results of this study indicate that the abundance of microplastics in Kijing Shells (Pilsbryoconchaexilis) at station I is 5.6 Mps/Ind, station II is 2.2 Mps/Ind and station III is 1.8 Mps/Ind. For contaminants, station I was 100%, station II was 80% and station III was 60%. The most types of microplastics were line and fragment types, while the most common microplastics found were red, blue and gray. Conclutions: Kijing Shells (Pilsbryoconchaexilis) originating from the Tallo River, Makassar contain microplastics. The highest abundance of microplastics was at station I at 5.6 Mps/Ind, station II at 2.2 Mps/Ind and station III at 1.8 Mps/Ind. For contaminants, station I was 100%, station II was 80% and station III was 60%.
Mussel Fish (Polymesoda Erosa) and Microplastics inTallo River, Makassar, Indonesia Yuliati; Anwar Daud; Anwar Mallongi; Burhanuddin Bahar; Hidayat
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16007

Abstract

Background: Microplastics are plastic particles whose diameter is less than 5 mm, which can be a problem for the environment and public health. This study aimed to determine the Mussel Shellfish’s microplastic content (Polymesodaerosa) in the Tallo Makassar River. Methods: This type of research is observational with a laboratory approach using Minitab 16 software to determine the microplastic content of Mussel Shellfish(Polymesoda erosa) in the Tallo Makassar River. Results: The results of this study indicated that the abundance of microplastics in the Mussel Shellfish (Polymesodaerosa) at station 1 was 3.8 Mps/Ind, while at station II and station III was 0.8 Mps/Ind. For contaminants, station 1 was 80%, station II was 60%, and station III was 40%. The most types of microplastics were line and fragment types, while the most common microplastics found were blue, red and transparent. Conclutions: Mussel Shellfish (Polymesodaerosa) originating from the Tallo Makassar River contain microplastics. The highest abundance of microplastics was at station I of 3.8 Mps/Ind, while stations II and III were at 0.8 MPs/Ind. Station I is 80% for contaminants, Station II is 60%, and Station III is 40%.
The Role of Chemical Shift Magnetic Resonance Imaging (SCMRI) to Differentiate Benign and Malignant Vertebral Lesions Yushaniaty Tottong; Rosy Setiawati; Paulus Rahardjo
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16008

Abstract

Legal Responsibility of Obstetric and Gynecological Doctor for Abortion with Indication of Fetal Deffects Widyasih Pritasari; Sri Mugirahayu; Askan; Mohammad Zamroni; MokhamadKhoirul Huda
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16009

Abstract

An undeveloped fetus in the mother’s womb leads to congenital disabilities where the baby can be fully dependent on his mother. Fetal defects in the Health Law are included in medical emergencies to be treated with full requirements and provisions regulated by law. Article 32 paragraph (1) points (a) and (b) of the Government Regulation on Reproductive Health explains the scope of indications of medical emergencies include a condition where it threatens the lives of mothers and babies and babies with disabilities where it resulted in a difficult for the baby to live outside the womb or the condition where the baby has some defects and cannot be cured. Article 75 paragraph (2) of the Health Law states if doctors do an abortion with indications of a medical emergency such as the fetus suffering from a severe genetic disease or congenital defects, the doctors cannot be convicted. So the principle of prudence is needed in determining the diagnosis to bring off an abortion because abortion is closely related to crime if it is not appropriately treated.
Factors Associated with the Second Dose of Measles Immunization in Children Under Two Years: An ecological Study Yenny Wulandari; Hario Megatsari; Agung Dwi Laksono; Mursyidul Ibad
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16010

Abstract

Measles is one of the leading causes of morbidity, mortality, and disability in children under two years worldwide. The study aimed to analyze factorsassociatedwiththe second dose of measles immunization in children under two years in 2019 in Indonesia. The study carried out the ecological analysis using secondary data from the 2019 Indonesian Health Profile. The Ministry of Health of the Republic of Indonesia reported that in 2019. The study takes 34 provinces as samples. The dependent variable is the coverage of the second dose of measles immunization in children under two years. The independent variable isthe ratio of primary health centers per district by province, the percentage of primary health centers with sufficient nurses, and the percentage of primary health centers with enough midwives. The results showed that three variables tended to be related to the second dose of measles immunization in childrenunder two years. The three variables consist of theratio of primary health centerper district, percentage of the primary health center with sufficient nurses, and percentage of the primary health center with enough midwives. The study concluded that the three independent variables analyzed tended to correlate with the coverage of the second dose of measles immunization in children under two years.
Developing the Latent Lip Print Using Hibiscus Sabdariffa (Roselle) Extract for Morphological Pattern Analysis in Thai Population Titichaya Meebuathong; Praew Suppajariyawat; Sirinart Chomean; Chollanot Kaset
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16011

Abstract

Background: A latent lip print can be important evidence, and specific substances are needed for the development of a latent lip print. However, collecting the lip print may difficult due to people who have sensitive skin with lipsticks and almost men who do not wear lipstick. Moreover, the enhancement methods of latent lip print are still lack of standardization and consistency. Aim: To develop a new staining method for the study of the lip print patterns Thai population.Method: The latent lip prints were collected from 24 males and 24 females. The ability of Roselle extract was investigated for developing latent lip prints on cigarette paper. The developed lip print was used for the morphological pattern analysis using Suzuki and Tsuchihashi’s classification criteria combined with Autodesk SketchBook. Result: The results revealed that Roselle extract exhibited potential as a staining dye for the development of latent lip prints on cigarette paper. Among the 24 males and 24 females, Type I was found to be most common and was present in 54.55% of the volunteers, followed by Types I’, II and IV (21.12%, 14.58%, and 9.03%, respectively). The least common patterns were Types III and V, each represented in 0.35% of the total volunteers. Conclusion: latent lip print could be used for study of lip print pattern by stained with Roselle extract. Moreover, a digital method using Autodesk SketchBook serves as an alternative method that provides ease in storing and identification of lip print pattern.