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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 17 Documents
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Search results for , issue "Vol 7 No 2 (2024): JIFI : Special edition" : 17 Documents clear
FORMULASI SEDIAAN MASKER GEL PEEL OFF DARI EKSTRAK KULIT BUAH PISANG AMBON LUMUT (Musa acuminata Colla) SEBAGAI ANTIOKSIDAN riauwati, Rosa; Nor Latifah; Erlina Fatmasari
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2004

Abstract

Kulit pisang Ambon Lumut mengandung senyawa flavonoid  berpotensisebagai antioksidan. Tujuan penelitian ini membuat  formulasi sediaan masker gel peel off dari ekstrak kulit buah pisang ambon lumut (Musa acuminata Colla)  memiliki aktivitas antioksidan. Basis yang digunakan Carbopol 940, dengan variasi 0,5 %, 0,75 %, dan 1%. Formulamasker gel peel off dibuat penambahan ekstrak kulit buah pisang ambon lumutdiperoleh dari hasil maserasi dengan konsentrasi 0,027 %, 0,082 %, dan 0,138%. evaluasi meliputi organoleptik, pH, homogenitas, Viskositas dan waktu mengering, ujiaktivitas antioksidan dilakukan dengan metode DPPH. Uji kesukaan dilakukan ke respondendengan mengoleskan ke punggung tangan responden. Hasil pembuatan basis yangpaling stabil dengan konsentrasi carbopol 940, sebesar 0,5 %. Hasil evaluasi sediaan yang stabildilihat dari parameter organoleptik, pH, homogenitas, Viskositas, dan waktu mengering selamapenyimpanan 28 hari. Dimana Nilai IC50 Dari ekstrak kulit buah pisang ambon lumut di dapatsebesar 27,467 ppm berdasarkan hasil uji aktivitas antioksidan sediaan masker gel peel off masukdalam katagori kuat dan sangat kuat Baik formula 1, 2, 3 yaitu 53,2 ppm; 44,4 ppm; dan 37,91ppm. Hasil uji kesukaan Masker gel peel off dengan konsentrasi 0,027 % yang paling banyak disukai.
ANALISIS KADAR TIMBAL (Pb) PADA BEDAK PADAT YANG BEREDAR DI BANJARMASIN MENGGUNAKAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Huzaeroh, Anifatu; Lestari, Yulianita Pratiwi Indah; Hayati, Mardia
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2072

Abstract

Pressed powder is a type of cosmetic that is commonly used and its safety must be guaranteed so that it is free from contamination. The aim of this research is to determine the presence of lead (Pb) contamination content in solid powder circulating in Banjarmasin using the absorption spectrophotometry method. atom. The test methods used include qualitative tests using 1 M NaOH reagent and quantitative tests that have been validated using Atomic Absorption Spectrophotometry. The results of the qualitative test showed that the five samples were reactive after being reacted with 1 M NaOH and produced a white precipitate. The method validation test results show that this method has linearity with a value of R=0.9996, LOD=0,019994243 ppm and LOQ=0,06664748 ppm. From the qualitative test, it was found that the five samples were indicated to contain lead, therefore it was continued with quantitative testing. Quantitative test results showed lead levels in samples coded A, B, C, D and E were 3,346 mg/kg; 4,894 mg/kg; 3,920 mg/kg; 3,284 mg/kg; dan 1,829 mg/kg.  It can be concluded that although there is still solid powder that contains lead (Pb), it is still below the safe limit for lead contamination, namely <20 mg/kg.
FORMULASI DAN UJI SIFAT FISIK SEDIAAN KRIM DENGAN VARIASI KONSENTRASI EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis Jack) Idawati, Idawati; Patimah, Raudatul; Ahdyani, Risa
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2073

Abstract

Elaeis guineensis Jack. leaves contain flavonoid compounds which act as antioxidants to protect the body from bad influences that can cause skin damage by free radicals. One of the technological developments to treat that can be assisted by cream preparations. Cream has various advantages, namely that it is easy to spread evenly, easy to clean or wash, practical and works on local tissue, not sticky, especially in o/w creams. The aim of this research was to determine the effect of variations in the concentration of palm oil leaf ethanol extract on the physical properties and antioxidant potential of oil palm leaf ethanol extract cream. Oil palm leaves were extracted using the maceration method using 96% ethanol solvent to produce a thick extract. Palm oil leaf ethanol extract is made in cream dosage form with varying concentrations of palm oil leaf ethanol extract, FI (0.5%), FII (1%), and FIII (1.5%). The cream preparations were tested for physical properties including organoleptic tests, homogeneity, pH, viscosity, stickiness and spreadability. Based on the test results, all cream formulas meet the test requirements for homogeneity, pH, viscosity, adhesion and spreadability according to the requirements for cream preparations for use on the skin.
MOLECULAR DOCKING ANALYSIS AND ADMET PREDICTION Of Caesalpinia sappan COMPOUNDS AS ANTIINFLAMMATORY THROUGH CYCLOOXYGENASE-2 INHIBITION Putri Maisarah, Marisa; Rahmawati; Andika
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2076

Abstract

Selective COX-2 inhibitors have been considered safer treatments than NSAIDs for inflammation from its side effect. Sappanwood was already known for its antiinflammatory activity, but its selectivity towards COX-2 has not been tested. The purpose of this study was to determine the potential activity of compounds in Caesalpinia sappan as anti-inflammatory agents by inhibiting COX-2 and determine their ADMET’s properties through in silico study. Qulified compound from Lipinski’s rule of five evaluation would be continued to the molecular docking using Autodock Tools and ADMET prediction using SwissADME and ADMETLab. Three compounds known to have the best free bond energy (ΔG) values were Caesalpiniaphenol A, Sappankalkon, and Deoxysappanone B with ΔG values respectively (-9.36 ; -9.23 ; -9.02 kcal/mol) and their inhibition constant values of (124.44 ; 172.43 ; 244.75 nM) respectively. Amino acid residues that are known to involve to the formation of hydrogen bonds in ligands are GLN 192 and PHE518. Toxicity results showed that these three compounds were predicted to be neither hepatotoxic nor hERG inhibitors, but 3-deoxysappanone B and sappankalkon was predicted to cause AMES mutagenicity and skin sensitivity. It can be concluded that these third compound has the potential as an inhibitor of the COX-2 enzyme.
COMPARISON OF LACTIC ACID BACTERIAL ISOLATES FROM VARIATIONS IN TIME FERMENTATION PROCESS OF CEMPEDAK SKIN Syifa Noorwina; siti nashihah
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2077

Abstract

Cempedak is a tropical native fruit from Indonesia and can be consumed by fermenting the skin fruit using a salt solution. The results of the fermentation called Mandai. Fermentation will be successful if there is a role of Lactic Acid Bacteria (LAB). Therefore, this study was conducted to determine the content of LAB in Mandai and isolates when fermented at different times. This study was carried out by dilution and the Pour Plate method, identifications such as morphological identification by gram staining and biochemical test by catalase t and TSIA test. Identification of this study was the observation of clear zone around the bacteria grown on MRSA media as a selective medium for LAB plus CaCO3. In this study, 5 samples of Mandai were used with different fermentation times. The results of the LAB isolation study in Mandai showed that the longer the Mandai fermentation was carried out, the more colonies there would be. While the LAB type was only found in sample 5 which was fermented within 20 weeks. The results obtained were following the characteristics of LAB, including gram-positive bacteria in the form of bacilli or cocci, not having catalase enzyme, and being able to ferment carbohydrates. 
OPTIMASI FORMULA KRIM EKSTRAK ETANOL DAUN PATIKAN KEBO (EUPHORBIA HIRTA L.) DENGAN METODE SIMPLEX LATTICE DESIGN Purwanto, Aris; Amrina, Fina; Riauwati, Rosa
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2081

Abstract

 The selection of an emulsifier in a cream formulation is a crucial factor, as the quality and stability of an emulsion. Additionally, an improper ratio of additives can result in unstable physical properties of the product during storage. Patikan kebo (Euphorbia hirta L.) is a plant that can be used as a natural component in anti-aging products. Optimization of 14 cream formulas was carried out using three optimization factors: ethanol extract of patikan kebo leaves (Euphorbia hirta L.) a concentration range of 1-3%, triethanolamine with a concentration range of 2-4%, and stearic acid within a concentration range of 1-3%. The optimization was performed using Design Expert software version 13 used the Simplex Lattice Design (SLD) method. The measured parameters included spreadability, pH, and viscosity. The research results a desirability value of 1.000, with extract ratio of 1%, TEA at 2%, and stearic acid at 3%. This combination resulted in the physical properties of the formulation, including a spreadability of 6.5 ± 0 cm, pH of 5.5 ± 0, and viscosity of 17,880 ± 0.0404 cP, which fulfilled the criteria set by the relevant cream formulation standards. 
ANALISIS PROFIL FITOKIMIA DAN AKTIVITAS ANTIOKSIDAN BATANG KAYU SMIDRA (Acronychia pedunculata (L.) Miq Fajeriyati, Nurul; Perdana, Farid; Musthapa, Iqbal
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2082

Abstract

The Rutaceae family is a family known to have antioxidant activity, one of the species included in the Rutaceae family is Acronychia pedunculata (L.) Miq commonly known as smidra. Plant parts of Acronychia pedunculata (L.) Miq such as roots, stems, leaves and fruit are used for traditional medicine for diarrhea, cough, asthma, wounds, boils, itchy skin, scales, pain and rheumatism and can be used as a fever reducer and can be used for the treatment of digestive tract disorders such as ulcers and intestinal infections. This study aims to determine the phytochemical profile and antioxidant activity of Acronychia pedunculata (L.) Miq smidra wood. In this study, the phytochemical profile analysis test was carried out, including the test of simplisia characteristics, monitoring the spectrum pattern using FTIR and chromatogram pattern using KLT and antioxidant activity test using DPPH method. The results showed that Acronychia pedunculata (L.) Miq smidra wood contains acetophenone derivative compounds with at least 5 compound components. Antioxidant activity test with DPPH method produces IC50 of 9.68 ppm which is included in the category of very strong antioxidants.
IDENTIFIKASI PEWARNA RHODAMIN B PADA PERONA MATA DENGAN KROMATOGRAFI LAPIS TIPIS Indra, Febryan Feriza; Jayadi, Lukky; Ikayanti, Retno
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2087

Abstract

Eyeshadow is a cosmetic that contains color pigments derived from natural/inorganic ingredients. The results of the BPOM survey conducted in 2021 to 2022 found that 16 sample products of blush on, nail polish, lip balm, eyeshadow and lipstick did not meet the requirements, containing prohibited ingredients, Rhodamine B. Considering the high use of cosmetics by the public and the report of eyeshadows that contain Rhodamine B, then it is necessary toidentify the Rhodamine B content in the eyeshadow. The aim of this study was to identify Rhodamine B in eyeshadow samples using Thin Layer Chromatography (TLC). The samples used were 4 different brands without BPOM registration numbers, consisting of 10 pallets, with pink to dark red colors. Identification was carried out using the TLC method with the mobile phase n-butanol: ethyl acetate: 25% ammonia (55:20:25). The test was carried out in 2 replications with the test results showing that 3 out of 10 samples showed the color and the Rf value that was in line with the Rf 0.63 of Rhodamine B standard. Further analysis was carried out by applying the UV light at 254 nm and 366 nm to the plate, and showed a typical fluorescence of Rhodamine B. 
TINGKAT KEPATUHAN PENGGUNAAN OBAT ANTIDIABETES ORAL DENGAN MENGGUNAKAN METODE PILL-COUNT PADA PASIEN PROLANIS SISTEM JAMINAN KESEHATAN INDONESIA (JKN) DIABETES MELLITUS TIPE 2 DI POLIKLINIK RS SATRIA MEDIKA PERIODE MARET – APRIL 2023 Meryta, Aries; Sabrina, Alifa; Eka Sari, Putri; Savitri, Fitri; Listyawati, Mega; Tuahuns, Farida
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2090

Abstract

Diabetes mellitus is a disease caused by increased blood sugar level due to lifestyle patterns or heredity. BPJS has a chronic program (PROLANIS) under the Health Insurance System (JKN) to control patient clinical parameters, prevent complications, and improve patient quality of life by monitoring patient compliance with treatment every month. This research was analyzed using the Pill-Count method, which is a method used to measure patient compliance in taking medication based on the remaining medication the patient has taken until the control date or return to the hospital. The assessment category is considered compliant if the percentage result is more than 80%. This type of research is observational with a cross-sectional approach. The total sample obtained was 37 patients in the March-April 2023 period at Satria Medika Hospital using the total sampling technique. The level of compliance based on the Pill-Count method shows that 14 patients (37.84%) were non-compliant and 23 patients (62.16%) were compliant. Based on the research results, it can be concluded that Satria Medika Hospital with the chronic program (PROLANIS) in March-April 2023 was in the non-compliant category as it achieved a compliance percentage of 62.16% (below the 80% threshold) using the Pill-Count method.
EVALUASI TINGKAT KEPUASAN PELAYANAN KEFARMASIAN PADA PASIEN BPJS RAWAT JALAN DI RUMAH SAKIT UMUM DAERAH RATU ZALECHA MARTAPURA DENGAN MENGGUNAKAN METODE CUSTOMER WINDOW QUADRAT (CWQ) Napisah, Siti; Muthaharah, Mustika; Mulyani, Tuty; Wulandari, Putrie; Wirahadikesuma, Ikhwan
Jurnal Insan Farmasi Indonesia Vol 7 No 2 (2024): JIFI : Special edition
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i2.2091

Abstract

Patient satisfaction assessment is a consumer response to the services provided according to the needs and expectations of patients towards pharmaceutical services. The purpose of this study was to determine the level of satisfaction with pharmaceutical services in outpatient BPJS patients at RSUD Ratu Zalecha Martapura and to determine the dimensions that affect the quality of pharmaceutical services that will be improved for patient satisfaction using the customer window quadrat method. The type of quantitative research with a descriptive cross-sectional design with a purposive sampling technique. The results of this study indicate that the level of satisfaction in each quality dimension is Tangible 92.73 (very satisfied), Responsiveness 87.63 (very satisfied), Reliability 90.83% (very satisfied), Assurance 87.58% (very satisfied), Empaty 95.71% (very satisfied). Based on the results of the CWQ analysis, there is 1 statement item that is the main priority in the improvements that must be made by the pharmacy, namely in quadrant A. The priority for improvement in item 2 "Speed ​​of time in delivering drugs".

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