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Bioscientist : Jurnal Ilmiah Biologi
Published by Universitas Pendidikan Mandalika
ISSN : 23385006     EISSN : 26544571     DOI : https://doi.org/10.33394
Core Subject : Science, Education, Agriculture, Social,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Social Sciences
Bioscientist : Jurnal Ilmiah Biologi (BJIB), receiving and publishing article in the form of research (scientific article) in the field of biology education and utilization of biological research in learning. Moreover, this journal bridges the gap between research and practice, providing information, ideas and opinion, in addition to critical examinations of biology research and teaching. Through the coverage of policy and curriculum developments, the latest results of research into the teaching, learning and assessment of biology are brought to the fore. Special emphasize are as follow: 1. Research on Learning Biology (Biology Learning Materials at All Education Levels). 2. Pure Research of Biology Developed or Studied to the Sources, Materials, or Instructional Media Biology (Biology Learning Materials at All Education Levels and Application in Society). 3. Curriculum of Biology Education at all Education Levels. 4. Class Action Research (CAR) and Lesson Study in Biology. 5. Other Qualitative Research of Biology Education. 6. The School Management and Biology/Science Laboratory Management. 7. Biology Learning Evaluation. 8. Teacher Professional Issues/Trends in Biology Education. 9. Another Study for the Scope of Biology Education. 10. Research on Environmental Education.
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 1,493 Documents
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In Silico Evaluation of the Antibacterial Potential of Methanolic Lo’i-Keta Extract Against DNA Gyrase in Staphylococcus aureus and Pseudomonas aeruginosa M. Agung Wisnu Pratama; Rozikin; Made Ayu Mirah Wulandari; Resna Hermawati
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 3 (2026): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i3.19511

Abstract

This study aimed to evaluate the antibacterial potential of bioactive compounds identified in the methanolic extract of lo’i-keta against DNA gyrase from Staphylococcus aureus (PDB ID: 3G75) and Pseudomonas aeruginosa (PDB ID: 6M1S) using an in silico approach. Bioactive compounds were identified by gas chromatography–mass spectrometry (GC–MS). Ligand preparation and molecular docking were subsequently performed using PyRx 0.8, while ligand–protein interactions were visualized using Discovery Studio. Ciprofloxacin was used as the positive control. GC–MS analysis detected 20 compound peaks, of which 13 compounds were validated and included in the docking analysis. Molecular docking results showed that cyclooctacosane exhibited the strongest binding affinity toward the DNA gyrase of S. aureus and P. aeruginosa, with binding energies of −8.3 and −8.2 kcal/mol, respectively. These values were more favorable than those of ciprofloxacin, which showed binding affinities of −7.7 and −7.4 kcal/mol, respectively. In addition, dioctyl benzene-1,2-dicarboxylate displayed a residue interaction pattern similar to that of ciprofloxacin within the active site of DNA gyrase. Hexadecanoic acid (palmitic acid) exhibited a more moderate binding affinity but was present at a relatively high abundance in the extract. These findings indicate that several bioactive compounds in lo’i-keta may form stable interactions with DNA gyrase, supporting its potential as a molecular target for antibacterial activity. Based on the in silico results, cyclooctacosane was identified as the leading candidate DNA gyrase inhibitor, while dioctyl benzene-1,2-dicarboxylate and hexadecanoic acid may serve as supporting candidates for the development of lo’i-keta-based antibacterial agents. This study provides a scientific basis for the traditional use of lo’i-keta; however, further in vitro and in vivo investigations are required to validate these findings.
The Effect of Deep Learning Instruction on the Motivation and Learning Outcomes of Grade 11 Students at SMA IT Nur Hidayah Ariela Prita Ayuningdyah; Annur Indra Kusumadani; Rina Astuti
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 3 (2026): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i3.20483

Abstract

This study aimed to investigate the effects of a deep learning–oriented instructional approach on the learning motivation and academic achievement of Grade 11 high school students. A quantitative quasi-experimental method was employed using a pretest–posttest control group design. The participants comprised 49 Grade 11 students, including 27 students in the experimental group and 22 students in the control group. Both groups received instruction on the human excretory system; however, the experimental group was taught using a deep learning approach, whereas the control group received instruction using a non-deep-learning approach. Data were collected using a learning motivation questionnaire, a 10-item pretest, and a 20-item posttest. The data were analyzed using the nonparametric Mann–Whitney U test and Wilcoxon signed-rank test. The findings demonstrated that the deep learning approach significantly improved the cognitive learning outcomes of Grade 11 students at SMA IT Nur Hidayah (Mann–Whitney U test, p = 0.045), with the Wilcoxon signed-rank test indicating a more consistent pattern of improvement. In contrast, no substantive difference was observed in learning motivation, with an increase of only 0.11%, which may be attributed to a ceiling effect resulting from the students’ initially high motivation levels. Empirically, this instructional approach was particularly effective in restructuring students’ cognitive understanding of complex subject matter, although it did not produce a substantial affective impact.
Plant Species Inventory at SMP Negeri 2 Lakea, Buol Regency, and Their Utilization as Learning Media Nurhidayah; Musdalifa Nurdin; Lilies; Aan Febriawan; Vita Indri Febriani; Lestari M.P. Alibasyah
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 3 (2026): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i3.20972

Abstract

This study aimed to identify and describe the plant species found on the grounds of SMP Negeri 2 Lakea, Buol Regency, and to develop a digital pocketbook in flipbook format as a contextual learning medium based on local biological resources. An exploratory descriptive method was employed, combining qualitative analysis for plant identification with descriptive quantitative analysis for media validation. Data were collected through surveys and systematic field exploration, direct observation, documentation, and plant identification based on morphological characteristics using relevant literature. The developed medium was validated by content, media, and instructional design experts and evaluated through responses from 30 seventh-grade students at SMP Negeri 2 Lakea. The study identified 35 plant species belonging to 20 families and representing four growth forms: herbs, shrubs, bushes, and trees. The recorded species included ornamental, medicinal, and shade plants, as well as naturally occurring wild species. These findings indicate that the school environment has substantial biological resource potential that can be utilized as a contextual learning resource. Based on student responses, the digital pocketbook was considered practical, concise, interactive, and helpful for understanding the learning material. The feasibility assessment yielded scores of 80% from the content expert, 83% from the media expert, 87% from the design expert, and 91% from student responses. The overall mean score was 85%, placing the medium in the highly feasible category. Therefore, the digital pocketbook based on plant diversity at SMP Negeri 2 Lakea is suitable for use as a contextual learning medium integrating local biological potential.

Page 150 of 150 | Total Record : 1493

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