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INDONESIA
Jurnal EduHealth
Published by SEAN INSTITUTE
ISSN : 20873271     EISSN : 28084608     DOI : -
Core Subject : Health,
Health Professions Public Health Veterinary
The EduHealt journal contains articles based on research results or equivalent in the health field. The research includes research related to the community environment as well as in the general public. Articles published in this journal have never been published/published by other media.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 1,299 Documents
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The Efficacy of Soursop Leaf Extract as a Hepatoprotector in White Rats Rattus norvegicus Induced by the Antituberculosis Drugs Isoniazid and Pyrazinamide Runggu Retno Justiani Napitupulu; Jenny Ria Sihombing; Bernika Ayu Frastika; Greace Ari Sulastry Aritonang
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Abstract

The use of antituberculosis drugs isoniazid and pyrazinamide triggers hepatotoxicity. Soursop leaves have a hepatoprotective effect because they contain antioxidant compounds that can help inhibit and prevent oxidative damage to the liver. This study aims to determine the effect of soursop leaf extract on the histopathological appearance of rat liver induced by isoniazid and pyrazinamide. This research is a laboratory experimental research using design posttest only control group design. This study used 24 rats Wistar divided into four groups and given treatment for 14 days. The negative control group was not given soursop leaf extract. The positive control group was given isoniazid and pyrazinamide, the treatment group I was given isoniazid and pyrazinamide and 1 hour later continued with soursop leaf extract 72 mg/day giving soursop leaf extract 144 mg/day. The dose of isoniazid used was 189 mg/day, while the dose of pyrazinamide was 252 mg/day. Termination of rats was carried out on the 15th day to collect rat liver organs. Furthermore, histopathological examination of the rat liver was carried out. The results showed that the rats in the negative control group had normal histopathological features. In the positive control group, there was a picture of hydropic degeneration. The histopathological picture of the rat liver in the treatment group 1 showed a picture of parenchymatous degeneration and in the treatment group 2, the liver cells were normal. Administration of soursop leaf extract affected the histopathological picture of rat liver induced by isoniazid and pyrazinamide.
QUALITY OF ETHANOL EXTRACT OINTMENT OF ARECA SEEDS (ARECA CATECHU L.) AS ANTI BACTERIAL STAPHYLOCOCCUS AUREUS QUALITY OF PINANG SEEDS EXTRACT ETHANOL (ARECA CATECHU L.) OINTMENT AS AN ANTI BACTERIAL STAPHYLOCOCCUS AUREUS Vivi Eulis Diana; Ririyen Dessy Natalia; Anisa Frida Tarigan
Jurnal EduHealth Vol. 10 No. 01 (2019): September, Jurnal EduHealth
Publisher : Sean Institute

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The areca nut plant (Areca catechu L) is a traditional plant that has long been used in traditional medicine for various types of diseases such as a stimulant, stomach disorders, worms, smallpox, cholera, venereal diseases and wounds or skin diseases. One of the factors causing skin infections is the bacteria Staphyloccocus aureus. Areca nut (Areca catechu L.) is a natural ingredient that contains antibacterial compounds, namely phenols, alkaloids, terpenoids, saponins, flavonoids, glycosides and tannins. Objective; to determine the antibacterial activity of an ointment preparation of ethanol extract of areca seeds ((Areca catechu L.) against Staphylococcus aureus. Method; this research used experimental research methods, namely the extract was obtained by maceration method with 96% ethanol, and concentrated using a rotary evaporator. Ethanol extract of seeds areca nut is mixed into the ointment preparation with a concentration of 20%, 30%, and 40%. Results; research shows that the average zone of inhibition in each sample of 20% areca nut extract is 7.86 mm, 30% is 12.23 mm, and 40% is 14.3 mm, positive control is 18.36 mm, negative control is 0 mm. Conclusion; from this research is that the ethanol extract of areca nut seeds can be formulated in ointment preparations with concentrations of 20%, 30%, and 40 % which can inhibit the growth of Staphyloccocus aureus bacteria. The concentration of areca nut ethanol extract which has the strongest antibacterial activity against the growth of Staphyloccocus aureus bacteria is a concentration of 40% with an inhibition zone of 14.3 mm.
Comparison of the Effectiveness of Dermapen Using Trambosit Plasma and Scar Serum Dermapen Actions on Scar Acne Areas on the Skin Surface of Wistar Female Rats (Rattus Norvegicus) Riza Al Djoefri, Mohamad; Wienaldi, Wienaldi; Chailur, Muhammad; Marthin Simbolon, Boyke
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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This study aimed to analyze and compare the effectiveness of the action of dermapen using plasma from platelets with the movement of dermapen using scar serum on pockmarked areas on the skin surface of female Wistar rats (Rattus norvegicus). The results of wound observations based on the period (days) with an average healing time of 10.4 days and 12 days needed by each mouse to close the wound in the PRP dermapen group were faster than the serum scar group. This can be explained by the PRP content containing growth factors important for wound healing and tissue regeneration, thus accelerating healing. Meanwhile, scar serum contains concentrates that are useful for nourishing and moisturizing the skin, which can easily penetrate the deepest layers of the skin, thereby accelerating skin regeneration. Further microscopic studies, such as histopathological studies, are needed to examine the number of fibroblasts.
Tests of Burn Wound Healing with Nanogel Preparations from Ethanol Extract of Andaliman Fruit Janice, Janice; Erwina Putri, Riri; Fioni, Fioni
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Andaliman (Zanthoxylum acanthopodium DC) is a plant known for its diverse bioactive compounds, including antimicrobial and anti-inflammatory properties. Nano-gel formulations were prepared using appropriate techniques, and their physicochemical properties, including particle size, pH, viscosity, and centrifugation stability, were evaluated. Additionally, organoleptic tests were conducted to assess the sensory characteristics of the nano-gels. Furthermore, an irritation test was performed to ensure the formulation's safety when applied to the skin. The percentage of wound closure was evaluated at various time points, including days 2, 4, 6, 8, 10, 12, and 14, comparing it to a commercially available wound healing product, Bioplacenton. Initial findings showed that the nano gel formulations exhibited favorable physicochemical properties, including appropriate particle size within the nano-scale range. The pH values were within an acceptable range, and the formulations demonstrated suitable viscosity and stability during centrifugation. Organoleptic tests indicated good sensory characteristics, and the irritation test showed the formulation's safety without significant skin irritation. The percentage of wound closure increased over time for all three concentrations (F1: 5%, F2: 10%, F3: 20%). In conclusion, nano gel formulations containing various concentrations of Andaliman extract exhibited good physicochemical properties, favorable sensory characteristics, and safe application on the skin. Moreover, they demonstrated promising wound healing effects, potentially comparable to commercial wound healing agents.
The Relationship Between Knowledge Of Young Women And The Benefits Of Sp8 Point Acupressure To Reduce Dysmenorrhea Pain In Sigulang Village, Padangsidimpuan Tenggara District, 2022 Dewi Aminasty Siregar; Rahmah Juliani Siregar; Elvi Suryani; Maryam Latifah Harahap
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

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Abstract

Dysmenorrhea pain causes 50% of all women in the world to suffer. In 2008, there were around 54.89% cases of primary dysmenorrhea in Indonesia. Meanwhile, the rest are sufferers in the secondary category. This pain makes women unable and unable to carry out activities and activities so that it can reduce the individual's quality of life. Dysmenorrhea is caused by the production of prostaglandin F2 alpha originating from endometrial cells in excessive amounts. One way that can be done to treat dysmenorrhea is with acupressure. This research was conducted in Sigulang Village, Padangsidempuan Tenggara District, with the aim of increasing knowledge and insight towards school-age adolescent girls. In order to reduce dysmenorrhea or menstrual pain non-pharmacologically by massaging using acupressure techniques. This research uses the Pre Experimental Design method in the research process. Counseling on acupressure techniques and assistance were carried out during this research process. After being given training and knowledge about dysmenorrhoea, young women can understand the benefits of acupressure massage to reduce menstrual pain or dysmenorrhoea. There was an increase in knowledge with a score of 81.81% of teenagers with good knowledge and 18.18% in the sufficient category.
Community Knowledge System about Karo Oil as Traditional Medicine on Ujung Labuhan Village, Namorambe, Deli Serdang Br Aritonang, Desi Anggryani; Puspitawati, Puspitawati
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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This article is the result of a study on Karo Oil as a traditional medicine, this article explains what ingredients are used in the manufacture of Karo oil, and how to make Karo Oil as well as the benefits of Karo Oil for the health of the body. This research was conducted on Jl. Ujung Labuhan, Namorambe, Deli Serdang. The type of research used is qualitative research using an ethnographic approach. Based on the results of the study, it is known that the ingredients used in the manufacture of this karo oil are ginger, pepper, kencur, shallots, and garlic.
Challenges to The Government’s Efforts to Fight HIV/AIDS: A Literature Review Sartika Sartika
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

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The government's efforts to deal with HIV/AIDS are essential and vital as a manifestation of their responsibility to improve the quality of healthcare system, as mandated by the law. This is urgent because HIV/AIDS problems are an ongoing issue that is remain unsolved while it is being exacerbated by the emergence of the COVID-19 pandemic, which has made the efforts to cope with HIV/AIDS became more difficult to do. Therefore, the government is working in various efforts to overcome HIV/AIDS in Indonesia. This study attempted to examine the extent of the government's role in addressing HIV/AIDS. Literature review is used as the method to carry out this study by collecting and identifying a number of scientific publications on related topics. The results of the analysis indicate that the government has attempted to play a role in dealing with HIV/AIDS, but majority of the studies considered that the government's role had not been effective. It is important to strengthen, applying new strategies, and the involvement of various stakeholders for HIV/AIDS prevention efforts to be effective.
The Effect Of Lower Rom Active On The Risk Of Falls In The Elderly Fanny Dewi Sartika
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

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A fall is an event in which a person accidentally falls sitting on the ground or in a lower place To determine the effect of active lower joint range of motion exercises on the risk of falls in the elderly. This research is research using the Quasy experimental design method with a cross sectional approach with Purposive Sampling technique. Elderly people at risk of falls discerning using the TUG test. Examination of the risk of falls using the TUG test were carried out pre and post. The results of the study showed that there was an effect of lower joint range of motion training on the risk of falls in the elderly with a p value <0.05. and than conclusion Lower ROM has benefits in reducing the risk of falls in the elderly
Relationship Level Of Knowledge, Attitude And Behavior To The Incidence Of Scabies At The Al Fatih Klaten Modern Islamic Boarding School Melok Tin Hartini; Retno Indrastiti; Rina Purnamasari
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
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Scabies is a skin disease that is most often found in densely populated environments such as Islamic boarding schools. This disease is caused by Sarcoptes scabiei homini. Education for students about scabies is necessary to increase awareness of hygiene behaviors. Education related to knowledge, attitudes and behavior to scabies has been carried out regularly every six months by the Dermatologist and Venereologist. This study aims to determine knowledge, attitudes and behavior to the incidence of scabies at Modern Islamic Boarding School Al Fatih, Klaten. This study used quantitative research design with a cross sectional design which was carried out in March 2023 at the Al Fatih Modern Islamic Boarding School, Klaten. The sample was 65 students were obtained by the total sampling method that met the inclusion criteria. Data obtained by direct examination and using a questionnaire. The diagnosis of scabies is made based on the criteria in the Regulation of the Ministry of Health of the Republic of Indonesia No. 5 of 2014 concerning Guidelines for Clinical Practice for Doctors in Primary Health Care Facilities. The results of the study showed that 40% of the respondents experienced scabies. Bivariate analysis with Spearman's Rank correlation test for the knowledge variable obtained p-value 0.873 where there was no significant relationship between knowledge and the incidence of scabies. As many as 40% of students who had a positive attitude were diagnosed with scabies. The relationship between behavior and the incidence of scabies was found to be p -value 0.03 where there was a significant relationship between behavior and the incidence of scabies. Amount of 40%students had a positive attitude were diagnosed with scabies. There was no significant relationship between knowledge and the incidence of scabies. However, there was a significant relationship between behavior and the incidence of scabies at the Al Fatih Modern Islamic Boarding School, Klaten Regency.
Literature Review : In Silico Study Of Lung Anticancer Proteins Alya Nafis; Fajar Prasetyo; Nur Sa’diyyah; Deviana Farhani; Nur Aenah
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
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Cancer is a disease caused by rapid and uncontrolled cell proliferation. Cancer is a massive disease characterized by rapid and uncontrolled cell proliferation. Cancer cells will continue to affect other cells around them until all tissues with cancer damage organs and nerves. One type of cancer with high cases in Indonesia is lung cancer. This cancer is a type of tumor whose source is the epithelial lining of the bronchial lung branches. Generally, therapy for the treatment of lung cancer is radiation, chemotherapy, surgery, and hormone therapy. In silico testing is a type of study with a computational approach to predict the activity of potential compounds as drugs. This article uses a type of literature review research with a total of 15 reference materials indexed on Google Scholar.

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