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Proceeding of Mulawarman Pharmaceuticals Conferences

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Published by Universitas Mulawarman

ISSN : - EISSN : 26144778 DOI : https://doi.org/10.25026/mpc

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 612 Documents

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Pengaruh Penggunaan Metode Lactic Acid-Sucrose dengan Microwave Assisted Extraction (MAE) terhadap Polifenol Total dari Herba Suruhan (Peperomia pellucida (L.) Kunth) Kharisma Ayu Tandi Datu; Nurul Fitriani; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

This study aim to determine the effect of use lactic acid and sucrose with assistance of Microwave Assisted Extraction (MAE) on Total Polyphenols from Herbs Suruhan (Peperomia pellucida (L.) Kunth). The dried sample of Herbs Suruhan was extracted using (green solvent) lactic acid-sucrose with a ratio of 1:1 g/g, 2:1 g/g and 3:1 g/g and the extraction conditions microwave strength was 50% for 10 minutes at a ratio sample and solvent 1:10 g/ml. Then the extract solution obtained to determine the total polyphenol level using the Folin Ciocalteu reagent and it absorbance was measured using a UV-VIS spectrophotometer at a wavelength of 791 nm. Based on the result of the study, obtained levels of polyphenols from each solvent condition used on the sample were 573,443 mg GAE/g (2:1), 472,479 mg GAE/g (1:1) and 420,14 mg GAE/g (3:1). It can be concluded that the lactic acid-sucrose method with microwave assisted extraction can be used to extract polyphenol compounds from Herbs Suruhan.

Ekstraksi Polifenol Total dari Umbi Bawang Dayak (Eleutherine bulbosa [Mill.] Urb.) menggunakan Metode Lactic Acid-Sucrose based Microwave Assisted Extraction Kurnya Kurnya; Hajrah Hajrah; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Dayak Onion (Eleutherine bulbosa [Mill.] Urb.) It is a plant that grows in Indonesia precisely in the Kalimantan area and has traditionally efficacious in curing various diseases such as diabetes mellitus, hypertension, breast cancer, cholesterol-lowering, and stroke. This study aims to determine the effect of using the lactic acid-sucrose based microwave-assisted extraction (MAE) method to extract total polyphenols from Dayak onion tubers (Eleutherine bulbosa [Mill.] Urb.). Dry samples were extracted using a lactic-sucrose acid (green solvent) solvent in the ratio of 1: 1, 2: 1, and 3: 1 g/g with 50% microwave strength for 10 minutes with a ratio of samples and solvents of 1:10 g /mL. Extracts that have been obtained then determined the total polyphenol levels using a UV-VIS spectrophotometer at a wavelength of 791 nm. Based on the results of the study, it was obtained the levels of polyphenols from each condition of the solvent used in the sample that is 28.73 mg GAE/g sample ( 1: 1 g/g solvent); 20.2 mg GAE/g sample ( 2:1 g/g solvent); 36.35 mg GAE/g sample ( 3:1 g/g solvent). From this study, it can be concluded that the MAE method can be used to extract polyphenol compounds from Dayak bulbs.

Kandungan Metabolit Sekunder Tempe Kacang Merah (Phaseolus vulgaris) Lita Nur Hanifa; Sabaniah Indjar Gama; Laode Rijai
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Soybean is a bean that is basically used as raw material for making tempeh, but the need for soybeans is not balanced with the amount of production in Indonesia. Therefore it is necessary to study the secondary metabolites needed in red bean tempeh (Phaseolus vulgaris) for alternatives to soybeans as another raw material from non-soy beans produced from Indonesia. The purpose of this study was to determine the content of secondary metabolites present in red bean tempeh. Samples were obtained from the Sulawesi region. The analytical method used in this study are qualitative submitting flavonoids, alkaloids, terpenoids, tannins, and saponins. The results obtained from studies that have been carried out namely red bean tempeh are proven to have all the composition of secondary metabolites with the exception of saponins.

Formulasi Sediaan Blush Cream dari Ekstrak Biji Kesumba Keling (Bixa orellana (L.)) sebagai Pewarna Alami Kosmetik Nova Mega Handayani; Lisna Meylina; Angga Cipta Narsa
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Blush is a type of decorative cosmetics used in the cheek area there used with the aim of adding aesthetic value to the face so that the face looks prettier, fresher and has more dimension. Currently there are many blush preparations on the market that contain hazardous chemicals, then a blush preparation made from kesumba keling seed extract containing bixin as natural coloring is made. The purpose of this study was to formulation and evaluate blush cream preparations by utilizing the acetone and maceration is concentrated with a rotary vacuum evaporator. Blush cream formula made using dyes from kesumba keling seed extract with a concentration of 0.5%, 1%, 2%, and 3% into the chosen base formula that produced color in successive orange-yellowish, soft-orange, dark-orange and orange-brownish color. Evaluations undertaken include organoleptic, homogeneity test, dispersion test, pH test, viscosity test and preferences test. The results obtained are based on parameters test, namely the four formulas enter the required value range. Aseptability test results showed that the preparation of blush cream with a concentration of 2% of the most preferred color of kesumba rivet seed extract and at a concentration of 0.5% was the easiest to spread.

Ekstraksi Polifenol Total dari Daun Kadamba (Mitragyna speciosa Korth) Menggunakan Metode Choline Chloride-Sorbitol based Microwave Assisted Extraction Ramila Hidayati; Dewi Rahmawati; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

This research was conducted to determine the influence of the use of the choline chloride-sorbitol based microwave assisted extraction (MAE) method against the total extraction of polyphenols from the leaf Kadamba (Mitragyna speciosa Korth). Simplisia extracted using solvent (green solvent) choline chloride-sorbitol with a ratio of 1:1; 1:2 and 1:3 g/g with sample and solvent ratio of 1:10 g/mL, microwave strength is 50% watt and performed for 10 minutes, the extract solution has been obtained and then done determination of total levels of polyphenols by using folin ciocalteu reagents and further measured its absorption with the UV-VIS spectrophotometer device at a wavelength of 770 nm. Based on the results of the study, obtained the levels of polyphenols from each comparison of solvent used against the sample of 334 mg of GAE/g samples (1:1 g/g solvent); 372 mg GAE/g samples (1:2 g/g solvents) and 299 mg of GAE/g samples (1:3 g/g solvents). Based on the results of the study can be concluded that the method of choline chloride-sorbitol based microwave assisted extraction (MAE) can be used to extract the polyphenols from Kadamba leaves easily, quickly and efficiently.

Aktivitas Antimikroba Ekstrak Etanol Biji Pinang Muda (Areca catechu) Sega Ade Lilyawati; Nurul Fitriani; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Thrush is an oral disease caused by bacterial and fungal infections. Treatment for this disease can be done by administering drugs that contain antimicrobial compounds. This study aims to test the ethanol extract of young areca nut against bacteria and fungi that cause Oral thrush. Young betel nut extract is obtained through maceration process using 96% ethanol. Then the activity of the Streptococcus sanguis bacteria and Candida albican fungus was tested. This test used the well method which was carried out on 5 variations of the concentration of young areca nut extract (2.5%; 5%; 7.5%; 10% and 15%) with one negative control (Na CMC). The results of the antimicrobial activity of young areca nut extract showed that young areca nut extract can inhibit Streptococcus sanguis bacteria with inhibition value are (9,961; 11,319; 13,390; 14,184; 14,704 mm) and Candida albican fungus are (7,482; 10,923; 14,695; 15,742; 17,325 mm) on 5 variations of the concentration.

Ekstraksi Polifenol Total dari Umbi Bawang Dayak (Eleutherine bulbosa [Mill.] Urb.) Menggunakan Metode Citric Acid-Glucose based Microwave Assisted Extraction Selvy Jumiatul Astati; Mirhansyah Ardana; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The use of environmentally friendly solvent-based expulsion methods today began to be widely used, one of which is a microwave-assisted extraction (MAE) using a citric acid-glucose acid solvent. The study aims to determine the influence of the use of citric acid-glucose based microwave-assisted extraction against the total extraction of polyphenols from Dayak onion bulbs (Eleutherine bulbosa [Mill.] Urb.).The dried samples were extracted using a solvent (green solvent) citric acid – glucose with a ratio of 4:1, 5:1 and 6:1 g/g with the extraction conditions in the form of microwave strength of 50% for 10 minutes with a sample and solvent ratio of 1:10 g/mL, then Extract solution obtained further determination of the total levels of polyphenols using Folin ciocalteu reagents, and its absorption was measured using a UV-vis spectrophotometer at a wavelength of 791 nm. Based on the results of the study, the total amount of polyphenols obtained from each of the solvent conditions used against the samples was 21.92 mgGAE/g samples, 13.86 mgGAE/g samples, and 14.38 mgGAE/g samples. From this study, it can be concluded that the concentration of citric acid in the microwave-based citric acid-glucose method is assisted by extraction according to the ability of the solvent in the competency of polyphenols from Dayak onion bulbs.

Kajian Interaksi Obat pada Pasien Gagal Jantung Di RSUD Abdul Wahab Sjahranie Kota Samarinda Yolanda Pratiska; Risna Agustina; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Cardiovascular diseases is first cause of death and heart failure is the end of all heart diseases and heart failure is causative factor enhancement of mortalities and morbidities heart failure patient. The purpose of the research is to know drug interaction in heart failure patient who undergoing hospitalization in RSUD Abdul Wahab Sjahranie in Samarinda. This research is non experimental and use retrospective to take a material during periods January – December in 2018. The result analyzed use descriptive evaluative and show heart failure case more suffer to the men (59.25%) at age 55-65 (35.80%) with the most of level education is senior high school (39.50%). The studies showed 163 drug interaction case with 18 (11.04%) minor interaction, 140(85.88%) moderate interaction and 5 (3.06%) major interaction.

Ekstraksi Polifenol Total dari Daun Kadamba (Mitragyna Speciosa Korth.) Menggunakan Malic Acid-Glucose Based Microwave Assisted Extraction Andi Yusniah; Yuspian Nur; Islamudin Ahmad
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

This study aims to determine the effect of the use of malic acid-glucose based microwave assited extraction (MAE) methods on total polyphenol extraction from kadamba leaves (Mitragyna Speciosa Korth). Samples that have been dried in the extraction using solvents (green solvent) Malic Acid-Glucose with a ratio of 1: 1 and 1: 3 g/g in several conditions including, microwave strength 50% for 10 minutes with a sample ratio and a solvent of 1:10 g/mL. Then the extract solution obtained was measured in total polyphenol levels using the folin ciocalteu (FC) reagent and the absorbance was measured at a wavelength of 791 nm using a UV-vis spectrophotometer. Based on the results of the study obtained levels of polyphenols from each condition of the solvent used is 258mg GAE/g sample (1:1 g/g solvent) and 292mg GAE /g sample (1: 3 g / g solvent). From this study it can be concluded that the method of malic acid-glucose based microwave assited extraction can be used to extract polyphenol compounds from Kadamba leaves quickly, easily and efficiently.

Uji Aktivitas Antioksidan Kombinasi Ekstrak Umbi Bawang Tiwai (Eleutherine bulbosa (Mill) Urb) dan Rimpang Kunyit(Curcuma domestica Val.) Yoni Miftahun Nafsiyah Agustin; Lisna Meylina; Yurika Sastyarina
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Bawang tiwai (Eleutherine bulbosa (Mill) Urb)a plant that originated from Kalimantan. This plant is traditionally used as a medicinal plant in the community. Bawang tiwai have bioactive compounds such as alkaloids, flavonoids, saponins which act as antioxidants. In addition bawang tiwai, turmeric (Curcuma domestica Val.)is a traditional medicinal plant used for seasoning and is a medicinal plant as antimicrobial, antioxidant, anti-tumor and anti-inflammatory. The aim of the research is to measure the antioxidant activity of the combination of extracts of bawang tiwai(Eleutherine bulbosa (Mill) Urb)and Turmeric (Curcuma domestica Val.). Antioxidant activity test used the DPPH (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm. Antioxidant activity was assessed based on% inhibition (IC50) which is the concentration of the sample solution is needed to reduce free radicals by 50%. The results obtained by measuring the antioxidant activity fromcombination extracts of IC50 was 185,118 ppm respectively.

Page 36 of 62 | Total Record : 612

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Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

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Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA