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Rolan Rusli
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Proceeding of Mulawarman Pharmaceuticals Conferences
Published by Universitas Mulawarman
ISSN : -     EISSN : 26144778     DOI : https://doi.org/10.25026/mpc
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 612 Documents
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Potensi Madu sebagai Penurun Tekanan Darah dan Kolestrol Mitha Fransiska; Jaka Fadraersada; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (559.559 KB) | DOI: 10.25026/mpc.v10i1.350

Abstract

Hypertension is an increase in systolic and diastolic blood pressure more than 140/90 mmHg. Honey has the potential to reduce blood pressure because it has 200 chemical substances. This study aims to ford the effectiveness of giving honey to reduce blood pressure and cholesterol levels in hypertensive patients, as well as knowing the content of secondary metabolites found in honey. The research method used was semi quantitative with pre and post procedurs. Honey contains secondary metabolites of alkaloids, flavonoids, tannins, and saponins. The results of the analysis of honey give a significant decrease in systolic pressure, diastole, heart rate and cholesterol levels. Consumption honey regularly effectively reduces blood pressure in hypertensive patients.
Pengaruh Media Booklet dan Reminder Terhadap Kualitas Hidup Pasien Kanker Serviks dengan Kuesioner EQ-5D Putu; Welinda; Adam; Angga
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.192 KB) | DOI: 10.25026/mpc.v10i1.351

Abstract

ABSTRAK Pendahuluan : Kanker serviks menempati posisi kedua di Dunia yang dapat menyebabkan kematian sebesar 80% pada Negara berkembang. Tujuan dari penelitian ini untuk melihat pengaruh pemberian booklet dan reminder pada penderita kanker serviks. Metode : Desain penelitian ini menggunakan One Group Pre Test and Post Test. Teknik pengambilan sampel menggunakan purposive sampling. Analisis data menggunakan uji statistik parametrik (paired t-test). Hasil : Pada kelompok booklet diperoleh EQ5D indeks dengan nilai sig p­= 0,433 sedangkan VAS method dengan nilai sig p= 0,079 dan pada kelompok reminder diperoleh EQ5D indeks dengan nilai sig p= 0,027 sedangkan VAS method dengan nilai sig p= 0,013. Kesimpulan : Tidak ada perbedaan yang signifikan pada kelompok booklet dan terdapat perbedaan yang signifikan pada kelompok reminder. Kata Kunci : Kualitas hidup, Kanker serviks, Booklet, Reminder
Formulasi Sediaan Masker Gel Peel Off Ekstrak Etanol Daun Salam (Syzygium polyanthum) sebagai Antioksidan dengan Metode DPPH Nur Zakiyah Darajat Abdurrahman; Nurul; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.921 KB) | DOI: 10.25026/mpc.v10i1.352

Abstract

Sediaan masker antioksidan gel peel off digunakan untuk menambah perlindungan kulit dari paparan radikal bebas. Salah satu tanaman yang memiliki aktivitas antioksidan adalah daun salam (Syzygium polyanthum). Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan pada ekstrak etanol daun salam dan sediaan masker gel peel off ekstrak etanol daun salam, serta mendapatkan formula terbaik masker gel peel off. Pengujian aktivitas antioksidan ekstrak etanol daun salam dilakukan menggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil). IC50 ekstrak etanol daun salam diperoleh sebesar 1,68 ppm. Hasil optimasi basis masker gel peel off didapatkan basis terbaik adalah menggunakan 1,5% carbopol. Hasil pengujian aktivitas antioksidan masker gel peel off dengan konsentrasi 500 ppm dan 1000 ppm ekstrak etanol daun salam diperoleh penghambatan terhadap DPPH sebesar sebesar 25,21 ppm dan 235,57 ppm.
Identifikasi Metabolit Sekunder Ekstrak Metanol Akar dan Batang Merung (Coptosapelta tomentosa ) yang Memiliki Aktivitas Antioksidan Menggunakan Metode KLT Autografi Nurul Yasmin; Wahyu; Angga
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (398.244 KB) | DOI: 10.25026/mpc.v10i1.353

Abstract

Secondary metabolites produced by plants have been known to have a variety of biological activities including antioxidants that serve to ward off oxidant compounds and free radicals. The roots of merung (Coptosapelta tomentosa) has been known to have strong activity as an antioxidant while antioxidant activity in the stem is not yet known to date. This research aims to determine the secondary metabolites that have antioxidant activity on the root extracts and the stem of the vines qualitatively. The root extract and the stem of the merung plant are extracted with a methanol solvent using the maceration method. Antioxidant activity and identification of secondary metabolites are carried out qualitatively by the method of autography using the 2.2-Diphenyl-1-Picrylhydrazyl compound (DPPH) and some reagents of the secondary metabolite. Antioxidant activity of the merung root extract is on spot with RF 0.08 and 0.66. Spot with the RF 0.66 shows the brown color when reacted FeCl3, fluorescent yellow in UV rays 254 and 366 nm after reacted AlCl3 and red when reacted with KOH. The antioxidant activity of the merung stem extracts is at Rf 0.16, 0.33, 0.58, 0.66, and 0.75. Spot with the Rf 0.16 shows the color of brown when reacted FeCl3 and fluorescent blue in UV rays 254 and 366 nm after reacted AlCl3. Secondary metabolites that have antioxidant activity on root extracts and stems are suspected to be derivative phenolic compounds derived from flavonoid compounds.
Uji Aktivitas Antibakteri Kombinasi Ekstrak Etanol Daun Sirih Hijau (Piper betle L.) dan Madu terhadap Bakteri Propionibacterium acnes Lucia Bilasonya Sakramentia; Nurul; Fajar
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (579.57 KB) | DOI: 10.25026/mpc.v10i1.355

Abstract

Green betel leaf (Piper betle L.) and honey have been scientifically known to have antibacterial activity. The antibacterial activity of green betel leaf is caused by the presence of compounds, such as tannins, flavonoids, saponins, alkaloids, and terpenoids. While honey is due to the high sugar content, the acidity and compounds from the flavonoid, glycoside, and hydrogen peroxide groups. This study aims to determine the antibacterial activity of the combination of these extracts against Propionibacterium acnes. Antibacterial activity was tested using the well technique agar diffusion method with green betel leaf extract concentrations of 2.5%, 5%, 7.5%, 10%, and 12.5% ??and combined each concentration with 100% of honey. The results obtained by the extract antibacterial activity at concentrations of 2.5%, 5%, 7.5%, 10%, and 12.5%, each combined with 100% of honey respectively at 11,81 mm; 14,45 mm; 15,48 mm; 16,77 mm; and 14,68 mm against Propionibacterium acnes. The results of this study indicate the combination of green betel leaf extract with a concentration of 10% and 100% honey produces the most effective inhibition zone.
Uji Aktivitas Tabir Surya Ekstrak Metanol Kulit Batang Kersen (Muntingia calabura L.) Secara In Vitro Tika Ristiani; Risna; Angga
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.203 KB) | DOI: 10.25026/mpc.v10i1.356

Abstract

ABSTRACT Kersen (Muntingia calabura L.) is a plant that is usually useful as a shade tree on the side of the road, which is thought to have the potential with sunscreen activity. This study aim to determine sunscreen activity of the bark based on %Te, %Tp and SPF values ??in vitro. The extraction was done by maceration using methanol solvent, and then phytochemical screening by color reaction test that showed the presence of flavonoids, phenolics, tannins, saponins, and terpenoid. Sunscreen activity and SPF values ??were determined by measuring the absorbance of extracts with several variations of concentration, using spectrophotometer. The results showed the best concentration for the sunscreen category was 700 ppm. Based on the value of %Te and %Tp, including standard suntan and sunblock categories. While based on the SPF value >15 shows that methanol extract is included in the category of ultra protection.
Uji Aktivitas Antioksidan Ekstrak Etanol Kulit Alpukat (Persea americana Mill.) terhadap Peredaman DPPH Amelia Siyanti; Nurul Fitriani; Angga
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.667 KB) | DOI: 10.25026/mpc.v10i1.357

Abstract

Avocado peel is contains chemical compound of alkaloid as antioxidant. So, has been research is to determine the antioxidant activity of ethanol extract avocado peel (Persea americana Mill.) inhibition of DPPH radical (2,2-diphenyl-1-picrylhydrazyl). The extraction method used maceration with 96% ethanol solvent. The ethanol extract avocado peel with variant concentrations are 50 ppm, 75 ppm, 100 ppm, 125 ppm, 150 ppm and ascorbic acid standard as a positive control with variant concentrations are 2 ppm, 4 ppm, 6 ppm, 8 ppm, 10 ppm. Antioxidant activity inhibit DPPH (2,2-diphenyl-1-picrylhydrazyl) radical reduction was measured using Uv-Vis spectrophotometry. The results of antioxidant activity was obtained at IC50 (inhibition concentration) from the ethanol extract avocado is 137.34 ppm and ascorbic acid is 13.18 ppm. The results of ethanol extract avocado peel has moderate antioxidant activity.
Analisis Efektivitas Biaya Penggunaan Obat Antihipertensi pada Pasien Preeklampsia di RSUD Abdul Wahab Sjahranie Periode 2018 Miftachul Ainin Chambali; Lisna Meylina; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (647.172 KB) | DOI: 10.25026/mpc.v10i1.358

Abstract

Preeklampsia adalah komplikasi pada kehamilan >20 minggu yang ditandai dengan meningkatnya tekanan darah disertai proteinuria serta terkadang diikuti udema.Tujuan penelitian ini adalah untuk mengetahui efektifitas biaya obat antihipertensi di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian dilakukan secara retrospektif terhadap catatan rekam medis. Hasil penelitian terhadap 62 kasus menunjukkan bahwa obat antihipertensi tunggal yang paling banyak digunakan yaitu nifedipin (50%). Penggunaan obat antihipertensi yang efektif dalam menurunkan tekanan darah sistol dan diastol pada terapi preeklampsia adalah obat antihipertensi tunggal nifedipin dengan nilai ACER Rp 57,47 dan Rp 150,40.
Kajian Efektivitas Jenis Terapi Obat Hipertensi Pada Pasien Yang Mengalami Komplikasi Di Rumah Sakit Samarinda Medika Citra Faisal Riyanda; Wahyu Widayat; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (653.192 KB) | DOI: 10.25026/mpc.v10i1.360

Abstract

Hipertensi merupakan penyakit yang meningkat beberapa tahun terakhir (Hasil Riskesdas menunjukkan kenaikan dari 25,8% pada tahun 2013 menjadi 34,1% pada tahun 2018), dan menjadi penyebab kematian nomor 3 setelah stroke dan tuberkulosis pada saat kematiannya mencapai 6,7% dari populasi kematian pada semua umur di Indonesia. Penelitian ini menggunakan metode penelitian deskriptif dengan mengumpulkan data secara retrospektif berdasarkan rekam medis pasien pada bulan Januari-Agustus 2019. Hasil penelitian yang menunjukkan pasien hipertensi yang terkait dengan kontribusi hipertensi ditingkat Prehipertensi mencapai 4%, ditingkat tahap 1 mencapai 28% dan ditingkat tahap 2 mencapai 68%. Terapi yang diberikan berdasarkan kode penelitian untuk kode K 1(Kombinasi ARB dan CCB) dengan presentase 44%. Sedangkan untuk terapi mencapai 80%, dan terapi mencapai 20%.
Potensi Kombinasi Ekstrak Daun Kokang dan Kersen Sebagai Tabir Surya Secara In Vitro Agata Tika Sari; Nurul Annisa; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (590.305 KB) | DOI: 10.25026/mpc.v10i1.361

Abstract

Kokang (Lepisanthes amoena (Hassk.) Leenh) dan kersen (Muntingia calabura L.) merupakan bahan alam yang memiliki aktivitas antioksidan yang tinggi. Penelitian ini bertujuan untuk mengetahui potensi ekstrak etanol daun kokang dan kersen baik dalam bentuk tunggal maupun kombinasi sebagai Tabir Surya secara in vitro. Penelitian ini mengukur aktivitas antioksidan menggunakan metode DPPH (2,2-Diphenyl-1-Picrylhydrazyl) dan pengujian aktivitas tabir surya %Te dan %Tp yang dihitung berdasarkan nilai absorbansi menggunakan spektrofotometer UV-Vis. Hasil pengujian menunjukan bahwa aktivitas antioksidan ekstrak etanol daun kokang (IC50 =18 ppm) dan daun kersen (IC50 =27 ppm) dan termasuk dalam kategori sangat kuat. Pengujian tabir surya menunjukkan bahwa kombinasi 1:2 ekstrak kokang dan kersen termasuk kategori proteksi ekstra dengan %Te sebesar 1,76% dan kategori sunblock dengan %Tp sebesar 1,36%.

Page 34 of 62 | Total Record : 612

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