Garuda - Garba Rujukan Digital

All

Proceeding of Mulawarman Pharmaceuticals Conferences

mpc
Website

Published by Universitas Mulawarman

ISSN : - EISSN : 26144778 DOI : https://doi.org/10.25026/mpc

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

LINGKUP DAN TUJUAN Lingkup naskah mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 612 Documents

43 44 45 46 47

Formulasi dan Uji Mutu Fisik Sediaan Sabun Cair Herbal Ekstrak Daun Kemangi (Ocimum sanctum L.): Formulation and Physical Quality Test of Basil Leaf Extract Herbal Liquid Soap (Ocimum sanctum L.) Sukma Dewi Ayu Anggraini; Panji Ratih Suci; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Acne is a skin problem that is often a problem for most teenagers in Indonesia. This acne can occur due to a lack of facial hygiene, which causes the growth of bacteria. Basil (Ocimum sanctum L.) is a plant that grows in Indonesia and contains alkaloids, saponins, flavonoids and tannins which can inhibit the growth of bacteria. The purpose of this study was to utilize Basil extract (Ocimum sanctum L.) into liquid soap preparation and evaluate the physical quality of the preparation. Basil extract (Ocimum sanctum L.) can be obtained by using the maceration method using 96% ethanol as a solvent. Liquid soap preparation formulations are made with extract concentrations of 2%, 4%, and 6% with a uniform liquid soap base. Evaluation of liquid soap preparations includes tests for homogeneity, organoleptic, pH, dispersibility, and high foam. The results of the three liquid soap formulations showed that the three formulations were homogeneous and there was no organoleptic change, the pH range of liquid soap 9-11 which fulfilled the pH requirements of liquid soap according to SNI No. 06-4085-1996, namely 8 - 11, the spreadability test range is 2.7 - 3cm and the foam height test range is 3 ? 8,5cm.

Parameter Non Spesifk dan Pengujian Toksisitas Ekstrak Etanol Daun Kokang (Lepisanthes amoena) Terhadap Larva Udang Artemia salina leach : Non-Specific Parameters and Toxicity Testing of Ethanol Extract of Kokang Leaf (Lepisanthes amoena) Against Shrimp Larvae Artemia salina leach Syarifah Irhamnah; Novita Eka Kartab Putri; Hadi Kuncoro
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The kokang leaves Lepisanthes amoena (Hassk.) Leenh) is a family of Sapindaceae which has been widely used as a traditional medicine, even now there are many formulas for the preparation of kokang leaves. The purpose of this study was to determine non-specific parameters, profile of TLC and to determine the acute toxicity of ethanol extract of kokang leaves against shrimp larvae of Artemia salina leach. The ethanol extract of kokang leaves was obtained by meseration method using 70% ethanol with a yield of 20.97%. The determination of non-specific parameters includes specific gravity, drying losses, total ash content, acid insoluble ash content. The ethanol extract of kokang leaves was analyzed by TLC profile using chloroform: acetone (8: 2) as eluent. Toxicity testing using the BSLT method and data were analyzed using Reed-Muench analysis. The results of the research to determine the non-specific parameters obtained are the average density 0.81 g; shrinkage in drying an average of 1.73%; total ash content on average 18.76%; acid insoluble ash content averaged 2.31%. The results of the TLC profile analysis were observations at UV 254 nm with an Rf value of 0.8. The results of observations on UV 366 nm showed two stains with Rf values of 0.7 and 0.8. The results of the acute toxicity test showed an LC?? value of 154.170 ppm. The conclusion based on the research results obtained non-specific parameters of kokang leaves. Based on the results of the TLC profile analysis of the compounds contained in the ethanol extract of kokang leaves, it tends to be non-polar. The LC?? value obtained shows that the ethanol extract of kokang leaves is toxic with a value of 154.170 ppm

Kajian In Silico Senyawa Turunan Pirazolina terhadap Bakteri Eschericia coli: In Silico Study of Pyrazoline Derivative Compounds against Eschericia coli Bacteria Tri Wulan Novi; Wisnu Cahyo Prabowo; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The development of antibiotics is needed to overcome drug resistance. Penicillin binding protein 5 (PBP5) Eschericia coli bacteria is one of the targets because it plays a role in maintaining cell shape. Pyrazolina is a compound that contains two nitrogen atoms where the two nitrogen atoms are close together and are responsible as an antibacterial agent that can disrupt the cell wall. The target molecule was downloaded from the Protein Data Bank (www.rcsb.org) (PDB ID: 6NTZ). The grid used is 20 ? x 26? x 32? with a center of 29,731?, -9,112 ? and 35,821 ?. Based on the results of the docking that has been carried out from 10 pyrazoline derivative test compounds, the resulting binding energy varies. There are 5 pyrazoline derivative compounds having binding energy lower than the natural ligands -6.27 kcal / mol. Compound P8 has the lowest value compared to other test compounds with a binding energy value of -7.69 kcal / mol. Based on the interaction, P2 and P3 compounds have interactions that are similar to the original ligands due to the presence of Pi-Donor hydrogen bonds with the amino acids SER 73 and SER 139. The results of molecular docking studies show that pyrazoline derivatives play a role in Eschericia coli bacteria.

Optimasi Basis Gel dan Evaluasi Sediaan Gel Anti Jerawat Ekstrak Daun Sirih Hitam (Piper betle L. Var Nigra): Gel Base Optimization and Evaluation of Anti-Acne Gel Black Betel Leaf Extract (Piper betle L. Var Nigra) Velita Rosari; Nurul Fitriani; Fajar Prasetya
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Gel is a semi-solid preparation that is clear, translucent and contains active ingredients. Acne is a skin disorder caused by the Propionibacterium acnes bacteria. Black betel (Piper betle L. var Nigra) contains alkaloids, flavonoids, saponins, tannins, steroids, triterpenoids, and polyphenolates which function as antibacterial. So that it can be formulated as an active substance in anti-acne gel preparations. The purpose of this study was to obtain a gel base with good physical stability and to evaluate the gel preparations mixed with black betel leaf extract (Piper betle L. var Nigra). Base optimization is done with 4 formulas with variations of Carbopol and TEA, namely B1, B2, B3, and B4. After getting the best gel base, then 3 formulas were made with various concentrations of black betel leaf extract (Piper betle L. var Nigra), namely F1 5%, F2 10%, and F3 15%. Then performed the physical stability test of the anti-acne gel preparation including organoleptic, homogeneity, pH, dispersion, adhesion, syneresis and viscosity for 16 days. The results obtained in the base optimization are clear, smell typical of bases, thick, homogeneous, pH range 6.1-6.8, spreadability 5.8-6.9 cm, adhesion 8-21 seconds, and viscosity 2.75. -5.81 Pa.s. The results obtained on the anti-acne gel are dark green, unique extract odor, thick, homogeneous, no syneresis, pH range 5.6-6.1, spreadability 6.0-6.9 cm, adhesion 14-21. seconds, and a viscosity of 2.12-6.81 Pa.s. The results showed that the gel base formula B4 was in accordance with the standard physical stability parameters. The addition of black betel leaf extract (Piper betle L. var Nigra) to the gel base affected the physical stability of the anti-acne gel preparation, but it was still included in the standard parameters of a good gel.

Formulasi dan Uji Mutu Fisik Sediaan Body Scrub dari Arang Aktif Sekam Padi (Oryza sativa): Formulation and Physical Quality Test of Provision of Body Scrub from Rice Husb Active Character (Oryza sativa) Chelsie Onesya Prolapita; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Rice husk (Oryza sativa) has a high content of activated carbon, activated charcoal is able to open clogged pores and improve skin cleansing by removing dead skin on the surface. Activated charcoal rice husk formulated sebagai scrubs using stearic acid, cethyl alcohol, and propilenglikol. Scrub as a scrub to remove dead skin cells using amylum oryzae. The concentration of activated rice husk charcoal used was 0% in the control formula, 8 % in formula I, 10% in formula II, and 12% in formula III. Evaluation Physical quality of body scrub based on parameters such as organoleptic, homogeneity test, pH test, spreadability test, adhesion test, emulsion type test. Body scrubs activated charcoal rice husk has a stable pH 7. Dispersibility formulation is 5,7cm, 5,8cm, 5,6cm. Rice husk activated charcoal body scrub is stable in room temperature storage or low temperature (2-8?C). All formulations evenly distributed homogeneously have stable color, smell and taste. Rice husk activated charcoal (Oryza sativa) can be formulated into a stable body scrub that meets the requirements. The most stable formulation was formulation 1 with a concentration of rice husk activated charcoal (Oryza sativa) of 8%.

Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Herbal Ekstrak Temu Putih (Curcuma zedoaria): Formulation and Physical Quality of Temu Putih Extract (Curcuma zedoaria) as Herbal Toothpaste Deva Rahayu Nurindah Kusuma Wardani; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Dental caries is one of the oral and dental problems in Indonesia. One of the causes of dental caries is the accumulation of dental plaque which is caused by food scraps that stick to the teeth and undergo fermentation by bacteria. Temu Putih (Curcuma zedoaria) is a native Indonesian plant that contains flavonoids, tannins and saponins that can inhibit bacterial growth. The purpose of this study was to formulate the extract of temu putih (Curcuma zedoaria) into toothpaste and evaluate the physical quality of these preparations. The temu putih extract was obtained by maceration method using 96% ethanol as a solvent. The toothpaste preparation formulation was made with a concentration of extract of temu putih (Curcuma zedoaria) 2%, 4%, 6% with a uniform toothpaste base. Evaluation of toothpaste preparations includes homogeneity, organoleptic, pH, dispersion and foam height tests. The test results of the three toothpaste preparations showed that the three formulations were homogeneous, there was no organoleptic change, the pH range of toothpaste from 6.5 to 8.0 which fulfilled the pH requirements of toothpaste according to SNI 12-3524-1995, namely 4.5 - 10, 5, the spreadability test range is 6.4 - 8.0 cm, and the foam height test range is 6.6 - 8.3 cm.

Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Herbal Ekstrak Temu Kunci (Boesenbergia pandurata Roxb) : Formulation and Physical Quality of Temu Kunci (Boesenbergia pandurata Roxb) as Toothpaste Reza Alfian Ardianto; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Dental caries is one of the oral and dental problems in Indonesia. One of the causes of dental caries is the accumulation of dental plaque which is caused by food residue that sticks to the teeth and undergoes fermentation by the bacteria Streptococcus mutans. Temu Kunci (Boesenbergia pandurata Roxb) is one of Indonesia's native plants which contains flavonoids, tannins and saponins which can inhibit bacterial growth. The purpose of this study was to formulate the extract of temu Kunci (Boesenbergia pandurata Roxb) into a toothpaste preparation and the physical quality of these preparations. The key extract was obtained by maceration method using 96% ethanol as a solvent. Divided into several toothpaste preparations made with the concentration of extract of temu Kunci (Boesenbergia pandurata Roxb) FI 2%, FII 4%, FIII 6% with uniform toothpaste. Evaluation of dental preparations including homogeneity, organoleptic, pH, dispersibility and foam height tests. The test results of the three formulations of dental preparations showed that the three formulations were homogeneous, there was no organoleptic change, the pH range of toothpaste from 6.5 to 8.0 which fulfilled the pH requirements of toothpaste according to SNI 12-3524-1995 were 4.5 - 10, 5, the spreadability test of 6.5 to 8.0 cm, and the test of the height range of the foam from 6.6 to 8.3 cm.

Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Ekstrak Biji Jintan Hitam (Nigella sativa): Formulation and Physical Quality Test of Toothpaste from Black Cumin Seeds (Nigella sativa) Vika Novia Agustyani; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Black Cumin seeds (Nigella sativa) have antibacterial activity because they contain thymoquinones, tannins, saponanins, and flavonoids. According to (Sinaga, 2018) black cumin seeds can inhibit the Streptococcous mutans bacteria that causes dental caries. The research conducted was experimental. The thick extract of black cumin seeds (Nigella sativa) is formulated into toothpaste by varying the concentration of the viscous extract of black cumin seeds (Nigella sativa). The concentration of the active substance used was 0% in the control formula, 2% in formula I, 4% in formula II, 6% in formulation III. Then performed a physical stability test of the toothpaste preparation consisting of homogeneity, pH, high foam, dispersibility, color, odor, and taste. The test was carried out for 28 days of storage. During 28 days of storage all formulations were stable, homogeneity, pH and high foam preparation were stable and met the standards. The particles are evenly distributed so that the preparation has a stable color, smell and taste. The thick extract of black cumin seeds (Nigella sativa) can be formulated into a toothpaste preparation that is stable and meets the requirements. The most stable formulation is formulation I with a concentration of 2% viscous black cumin seed (Nigella sativa) extract.

Hubungan Tingkat Pengetahuan dan Persepsi Tenaga Kesehatan Mengenai Peranan Farmakogenomik: The Relationship Scale Between Knowledges and Perceptions of Health Practitioners about the Role of Pharmacogenomics Muhammad Akib Yuswar; Robiyanto Robiyanto; Eka Kartika Untari; Shoma Rizkifani
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Research on the extent to which health practitioners in West Kalimantan understand the important role of pharmacogenomics have not been reported to date. West Kalimantan (Kalbar) is known as a province characterized by three main ethnicities, namely Chinese, Malay and Dayak. Therefore, the potential application of pharmacogenomics for the treatment of patients in health facilities across the province is very possible. This study aimed to measure the level of knowledge and perceptions of health practitioners (participants) about the role of pharmacogenomics in patient treatment plans. This research is descriptive with a questionnaire-based survey method. The data analyzed is primary data from the answers of participants to the online questionnaire. Based on the responses of 100 participants (involving doctors, pharmacists, nurses, midwives, and others) from various cities and districts in West Kalimantan, it was found that the level of knowledge was very good (74.0%), good (18.0%), and not good. (8.0%). The level of participants' perceptions of the role of pharmacogenomics are those who have positive perceptions (97.0%) and negative perceptions (3.0%). It can be concluded that 74% of health practitioners in West Kalimantan have a very good level of knowledge and 97% of them own a positive perception of the importance of pharmacogenomics.

Pengaruh Tempat Tumbuh Terhadap Kadar Alfa Tokoferol Pada Buah Mengkudu (Morinda Citrifolia L.): The Effect of Location on Alfa Tocopherol Levels in Noni Fruit (Morinda Citrifolia L.) Sri Gustini Husein; Wiwin Winingsih; Nurdianti Nurdianti; Achmad Zainuddin
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Alpha tocopherol (?-tocopherol) contained in noni fruit (Morinda citrifolia L.) is one of the antioxidants that contribute to pharmacological effects. The noni plant is a tropical plant that has broad growing requirements, so that this plant can grow anywhere. Although easy to find, the environmental conditions where noni grows will have an influence on the amount of ?-tocopherol it contains, one of which is the difference in where it grows. The purpose of this study was to determine the levels of ?-tocopherol in the n-hexane fraction of noni fruit, which grows in three different growing places. Analysis for ?-tocopherol by High Performance Liquid Chromatography (HPLC) with a validated analytical method. The results of system suitability test HPLC System for ?- tocopherol analysis were as follows isocratic elution system of a mobile phase 100% methanol, uv detector at a wavelength of 292 nm using the column C18 (150 ? 4, 6mm, 5?m) flow rate of 1 ml / min. The method had linear concentration range from 1-25 ppm, with R2 0.9967. The accuracy of this method that represented by recovery was 98.02-99.252%. The precision of this method that expressed by Relative Standard Deviation (RSD) was 0.262% and has good specificity. From the analysis, it was found that the content of ?-tocopherol in noni fruit was different and had a positive correlation with the height where it grew, namely in Pameungpeuk (18 m asl) of 0.0316%; Kiaracondong (173 m asl) of 0.0637%; and Lembang (1200 m asl) at 1.0853%.

Page 45 of 62 | Total Record : 612

43 44 45 46 47

Filter by Year

2015 2023

Filter By Issues

All Issue Vol. 18 (2023): Proc. Mul. Pharm. Conf. Vol. 17 (2023): Proc. Mul. Pharm. Conf. Vol. 16 (2022): Proc. Mul. Pharm. Conf. Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.) Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf. Vol. 12 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 12 (2020): Proc. Mul. Pharm. Conf. Vol. 11 (2020): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 10 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 9 (2019): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 8 (2018): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 7 (2018): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 6 (2017): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 5 (2017): Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 4 (2016): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 3 (2016): Spesial Issue of Mulawarman Pharmaceuticals Conference Proceeding (Prosiding Semnas T Vol. 3 (2016): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 2 (2015): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa Vol. 1 (2015): Proceeding of Mulawarman Pharmaceuticals Conferences (Prosiding Seminar Nasional Kefa More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Rolan Rusli

Contact Email rolan@farmasi.unmul.ac.id

Phone +6285222221907

Journal Mail Official admin@farmasi.unmul.ac.id

Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location Kota samarinda, Kalimantan timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA