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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 25 Documents
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Search results for , issue "Vol 4 No 1 (2019): JIIS" : 25 Documents clear
PENGETAHUAN PASIEN TENTANG UPAYA PENCEGAHAN STROKE DENGAN TERAPI NON-FARMAKOLOGI DI POLI DALAM RSU DR. SLAMET GARUT Theresia Eriyani; Iwan Shalahuddin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.031 KB) | DOI: 10.36387/jiis.v4i1.197

Abstract

Hypertension that occurs for years can cause various problems. Effort to measure blood pressure regularly and treat it effectively, aim to prevent complications. Someone who usually smoke and let high cholesterol levels in the blood more at risk of complications. One of the complications caused by hypertension is stroke, so it is necessary to control the hypertensive patients because hypertension control can be the key prevention of stroke. This study aims to find out how the knowledge of hypertensive patients about stroke prevention efforts by way of non-pharmacologic therapy, Non-pharmacological therapies here include regular exercise, low-salt diet and lifestyle changes.The type of research is descriptive research, the polpulation in this study is all hypertensive patients who come to the Poly In dr. Slamet Garut in August 2012. The sample in this research using non probability method with accidental sampling with 25 samples. Obtained that the knowledge of hypertensive patients about the effort of stroke prevention by non-pharmacological therapy in Poli In dr. Slamet Garut from 25 respondents, have the best knowledge as much as 28.00%, knowledge enough 36.00%, have knowledge less 36.00%.Most of the respondents who studied about the knowledge of hypertensive patients about stroke prevention efforts by non-pharmacological therapy in Inner Polyclinic dr. Slamet Garut has less knowledge and enough knowledge respectively that is 36.00% (9 persons).
PENGARUH FAKTOR KARAKTERISTIK SOSIODEMOGRAFI TERHADAP PENGETAHUAN TENTANG OBAT GENERIK Nurul Mardiati; Depy Oktapian Akbar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.463 KB) | DOI: 10.36387/jiis.v4i1.200

Abstract

Kebijakan penggunaan obat generik telah menjadi salah satu implikasi yang diharapkan Pemerintah Indonesia melalui program Jaminan Kesehatan Nasional (JKN). Pasalnya melalui program JKN maka seluruh fasilitas kesehatan diwajibkan mengacu pada Formularium Nasional (Fornas) yang notabene sebagian besarnya merupakan obat generik. Jauh sebelum program JKN digulirkan oleh Pemerintah, sebenarnya Pemerintah telah mengeluarkan berbagai kebijakan guna terus mendorong peningkatan penggunaan obat generik. Akan tetapi hingga sejauh ini, penggunaan obat generik di Indonesia secara umum hanya mempunyai pasar sekitar 7% dibandingkan dengan obat branded generik. Pengetahuan yang buruk tentang obat generik dapat menyebabkan angka penggunaan obat generik pada masyarakat sulit untuk meningkat. Tujuan penelitian yaitu mengidentifikasi pengaruh faktor sosiodemografi terhadap pengetahuan tentang obat generik. Rancangan penelitiannya deskriptif-analitik. Penelitian menggunakan desain survey cross sectional. Cara pengambilan sampel dilakukan dengan proportional stratified random sampling. Cara pengumpulan datanya dilakukan dengan survey menggunakan kuesioner checklist dalam dua pilihan jawaban yaitu benar dan salah. Analisis data dilakukan dengan analisis unvariat (statistik deskriptif) dan bivariat uji t (chi-square, alternatif uji kolmogorov-smirnov). Hasil penelitian menunjukkan pengetahuan tentang obat generik dipengaruhi oleh tingkat pendidikan, tingkat penghasilan per bulan dan sumber utama informasi obat-obatan.
ANALISIS EFEKTIVITAS TERAPI ANTIRETROVIRAL PADA PASIEN HIV/AIDS RAWAT JALANDI RSUP FATMAWATI JAKARTA TAHUN 2016 Yusi Anggriani; Alfina Rianti; Jenny Pontoan; Yulwa Juwita
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.813 KB) | DOI: 10.36387/jiis.v4i1.212

Abstract

The increasing of HIV/AIDS every year become a health problem in Indonesia. Patients of HIV/AIDS should use longterm Antiretroviral (ARV) therapy of antiretroviral therapy to support the success of antiretroviral therapy. The objective of this study was to know and compare the effectivity of four ARV combination. The four ARV combination are combination A (AZT+3TC+NVP), combination B (AZT+3TC+EFV), combination C (TNF+3TC+NVP), combination D (TNF+3TC+EFV) base on increasing CD4. This study cohort-longitudinal design. Samples for this study were taken by total sampling using all data of HIV/AIDS outpatients at RS Fartmawati on 2016. The inclusion criteria were patients of (≥17 years old), received treatment of either one of the four ARV combination, and had data of CD4 from laboratory result before and 6-12 months after the treatment. Data were taken from patients medical record and analyzed with non-parametric Kruskal Wallis-test. The study results showed of 124 patients had increased the CD4 mean >100 sel/mm3 one year after the treatment. The average rate of increment of each combination of antiretroviral therapy on a median CD4 cell count of 1 year was a combination of A (73.93), combination B (70.87), combination C (48.73), combination D (55.57) and there was a significant difference in CD4 cell gain in patients taking combination A-C (p value = 0.047), combination A-D (p value = 0.041), and combination B-D (p value = 0.045) at the evaluation on 1 year. Conclusion, combination A is more effective than combination B, D and C.
FORMULASI ORALLY DISINTEGRATING TABLET (ODT) ASETOSAL DENGAN VARIASI KONSENTRASI KOMBINASI AVICE Hayatus Sa'adah; Yulistia Budianti S.; Akhmad Andy Sandra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.066 KB) | DOI: 10.36387/jiis.v4i1.216

Abstract

Acetylsalicylic acid or better known as acetosal or aspirin is a drug that has efficacy as an antiplatelet which is widely used as a drug to prevent and treat stroke. Currently acetosal is often found in many preparations, one of which is in conventional tablet preparations. Stroke sufferers really need a drug in tablet dosage form that is easy to consume, has a relatively fast duration of drug action, and with more practical drug administration. Therefore, an acetosal preparation is made in the form of Orally Disintegrating Tablet (ODT) which has several advantages, including being more practical to use because it can be consumed without using water and can be used by patients who are difficult to swallow conventional tablets. Research conducted on acetosal ODT formulation with variations in the combination concentration of Avicel PH 102 and mannitol as filler material. In this study, the physical properties of ODT acetosal were tested by varying the combination concentration of Avicel PH 102 and mannitol as a filler with a ratio of F1 = 0: 1, F2 = 0.25: 0.75, F3 = 0.5: 0.5 , F4 = 0.75: 0.25, and F5 = 1: 0. The ODT evaluation was carried out in the form of examining the weight uniformity test, hardness test, friability test, and tablet disintegrating time test. The results of the study obtained the best formula is F4 with a comparison of Avicel PH 102 and manitol 0.75: 0.25 that meets the requirements of physical properties of ODT with the average value of tablet weight uniformity test 382.5 mg ± 0.007, tablet 2 hardness test, 52 kg / cm2 ± 0.396, tablet friability test 0.53% ± 0.153, and tablet disintegrating time test 21 seconds ± 3.605.
FORMULASI DAN UJI AKTIVITAS MASKER GEL PEEL-OFF ANTIJERAWAT EKSTRAK ETANOL BAWANG DAYAK (Eleutherina palmifolia (L.) Merr) TERHADAP BAKTERI Staphylococcus aureus SECARA IN VITRO Husnani Husnani; Fitri Sri Rizki
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.686 KB) | DOI: 10.36387/jiis.v4i1.218

Abstract

Dayak union contains compounds group of alkaloids, flavonoids, saponins, tannins, glycosides, and triterpenoids which have antiacne effect. The aim of this research was to provide peel-off mask gel formula from ethanol extract of dayak union and tested its physical properties and their antibacteria activities to Staphylococcus aureus. Peel-off mask gel formulation from extract of dayak union made with various extract concentrasion which are 50 mg/ml, 75 mg/ml dan 100 mg/ml with Polyvinyl Alcohol (PVA) base as gelling agent that has adhesive properties or could make flim layer thatt could peel off after its dried. Peel-off mask gel tested its physical properties, which are organoleptic, homogenity, pH, spread capacity, drying time and viscosity. The results of physical evaluation obtained that 1st formula has calm texture, brown-red colour and unique scent of dayak union, viscosity 60.666 cps, drying time for 725,67 seconds, spread capacity 4.49 cm, and pH 5. Results of antiacne activity shows that 1st formula is more effective that 2nd and 3rd formula, with inhibition zone diameter to Staphylococcus aureus is 0.87 cm. So it conclude that 1st formula is the best formula y ist physical and can give inhibition zone on the growth of Staphylococcus aureus.
PENETAPAN KADAR FLAVONOID EKSTRAK TERPURIFIKASI UMBI BAWANG DAYAK (Eleutherine palmifolia (L). Merr) SECARA SPEKTROFOTOMETRI Siti Jubaidah; Eka Siswanto; Heri Wijaya; Muhammad Putu Aditya
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.018 KB) | DOI: 10.36387/jiis.v4i1.225

Abstract

Eleutherine palmifolia (L) Merr. is one of the plant that has function as medicine. One of the compound which much contained in ethanol extract of dayak union is flavonoid, so that could separate with purification. The aim of this study is to determine flavonoid levels in purified extract of dayak union root with various drying treatments using UV-Vis spectrophotometry and to find out which drying treatment that obtaine the highest flavonoid levels.Drying treatment of dayak union root simplicia were with direct sunlight for 6 hours (P1), dried by oven with temperature 60ºC for 6 hours (P2), dried by covered with black clothes (P3). Dayak union root simplicia extracted by maceratiin method using ethanol 70%, and purified step by step using n-hexane solvent. Flavonoid levels test of purified extract of dayak union root carried outby UV-Vis spectrophotometry method.The results of UV-Vis spectrophotometry obtained flavonoid levels of purified extract of dayak union root in dried by direct sunlight (P1) was 0.79%, dried by oven with temperature 60ºC (P2) was 1.57%, and dried by coveredwith black clothes (P3) was 1.02%. LSD test shows (P<0.05) the significant differences between flavonoid levels with different drying treatment.
PENGUKURAN KUALITAS HIDUP PASIEN HEMODIALISIS GAGAL GINJAL KRONIK DI RSUD ULIN BANJARMASIN MENGGUNAKAN INSTRUMEN EQ5D Saftia Aryzki; Maudy Namirah Raudatullis Wanda; Yugo Susanto; Mochammad Maulidie Alfiannor Saputera; Aditya Maulana Perdana Putra; Karani Karani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.29 KB) | DOI: 10.36387/jiis.v4i1.230

Abstract

Chronic renal failure is a progressive and irreversible renal function disorder in which the body's ability to fail to maintain metabolism, fluid and electrolyte balance. Chronic kidney failure can interfere with the quality of life of patients, it is necessary to measure the quality of life of patients with chronic renal failure. Measuring the quality of life of patients with chronic renal failure using the Indonesian version of the EQ5D questionnaire. The purpose of this study was to determine the quality of life of chronic renal failure hemodialysis patients in RSUD Ulin Banjarmasin using the EQ5D instrument. This study is an observational study conducted prospectively. Data was collected by filling out the EQ5D questionnaire by all patients with chronic renal failure. The population of this study were chronic renal failure patients who underwent hemodialysis in Hemodialysis Outpatient Services at Ulin Banjarmasin Hospital in June-July 2018 as many as 360 patients and a sample of 207 patients who met the inclusion and exclusion criteria using non random sampling / non-probability sampling techniques accidental sampling. Based on the research that has been done in the Hemodialysis Outpatient Hospital Ulin Banjarmasin, it was found that the average quality of life was 0.792, with a quality of life ≥ 0.792 of 69 patients (33.33%) in the category of good quality of life and quality of life ≤ 0.792 138 patients (66.66%) in the poor quality of life category.
PENETAPAN PARAMETER NON SPESIFIK DAN SPESIFIK EKSTRAK DAUN SALAM (Syzgium polyanthum) Lina Widiyastuti; Widyasari Putranti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.324 KB) | DOI: 10.36387/jiis.v4i1.232

Abstract

Bay leaf extract is one of the traditional medicinal ingredients which is efficacious as an antihyperlipid. The quality of the extract is a parameter to guarantee the optimal therapeutic effect. Determination of non-specific and specific parameters of bay leaf extract (EDS) is needed to ensure the quality of raw materials used in hyperlipid therapy. The bay leaf extract was obtained from Bantul, Yogyakarta and macerated using 70% ethanol. EDS tested the parameters of ash content, water content, soluble ethanol extract content, water soluble extract content, acid insoluble ash content, quantitative qualitative analysis, total plate number analysis, analysis of yeast mold number, specific gravity, qualitative analysis. This study was obtained by EDS meeting the standardization of non-specific and specific parameters according to Indonesian Herbal Pharmacopoeia.
PENGEMBANGAN SEDIAAN EMULGEL MENGANDUNG MINYAK BIJI ANGGUR (Vitis vinifera L.) DAN UJI AKTVITAS ANTILUKA TERHADAP TIKUS WISTAR JANTAN (Rattus norvegicus) Sani Ega Priani; Indah Ayu Lestari; Fetri Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.718 KB) | DOI: 10.36387/jiis.v4i1.233

Abstract

Grape seed oil has wound healing activity since contains compounds such as flavonoids, polyphenols, saponins and linoleic acid. The purpose of this study is formulate emulgel containing grape seed oil with good physical characteristic and observed the wound healing activities of the oil and formulated emulgel. The research was begin with grape seed oil characterization and required HLB determination. The emulgel was made using combination Tween 80 and Span 80 as emulgator and carbomer as gelling agent with variation of oil concentration (10%, 20% and 30%). The formulation then subjected to physical evaluations including organoleptic, pH, spreadability, viscosity and rheology, sterility, and stability tests. Wound healing activity test of selected formula was done on seven groups of male Wistar rats. The emulgel containing grape seed oil with HLB value 8, has good physical, sterility, and stability characteristics. In vivo activity test showed that emulgel containing 20% and 30% grape seed oil have wound healing activity that statistically different compared with control (P<0.05) and the activity was not statistically different with marketed product (P>0.05).
PERBANDINGAN BIAYA RIIL DENGAN TARIF INA-CBG’S PENYAKIT STROKE PADA ERA JAMINAN KESEHATAN NASIONAL DI RS ISLAM SULTAN AGUNG Ken Wirastuti; Indriyati Hadi Sulistyaningrum; Erwin Budi Cahyono; Arifin Santoso; Zaki Miftahudin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.375 KB) | DOI: 10.36387/jiis.v4i1.244

Abstract

The implementation of INA CBG's system is not yet optimal because INA CBG’s rate in fact not yet fulfill hospital real cost. The purpose of this research was to compare the INA-CBG’s rate and real cost and also to look the factors affecting has difference the big real cost in patient with stroke in JKN era at Sultan Agung Islam Hospital between January 2017 and October 2017.Research using descriptive analysis, the data were analysed by Mann-Whitney test was used to compare real cost and INA-CBG’s rate. And the Mann-Whitney followed Kruskal-Wallis to determine the components of the factors affect real costs.There was a difference between the real cost and the INA-CBG's rate for hospitalization of (Rp -12,184,500) and outpatient care of (Rp -1,949,300). Factors that affect the real cost are type of nursing class (0,009), LOS (0,019) and age (0,045).The conclusion of this study is that there was a difference between the real cost and INA-CBG’s rate in patient with stroke in JKN era at Sultan Agung Islam Hospital between January 2017 and October 2017. Factors that affect the big real cost are type of nursing class, LOS and age.

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