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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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ANALISIS BIAYA KEMOTERAPI PADA PASIEN RAWAT INAP KANKER PAYUDARA PESERTA JKN DI RSUD ULIN BANJARMASIN Noor Aisyah; Tri Murti Andayani; Diah Ayu Puspandari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.474 KB) | DOI: 10.36387/jiis.v3i2.189

Abstract

Kanker payudara merupakan jenis penyakit katastropik yaitu penyakit yang high cost, high volume dan high risk yang menyebabkan terjadinya pembengkakan biaya penyakit. Berdasarkan data klaim Indonesian-Case Based Groups sampai dengan bulan bayar Januari 2016, penyakit kanker menduduki urutan kedua setelah jantung yang paling banyak membutuhkan biaya pengobatan, yaitu Rp1,8 triliun. Tujuan penelitian ini untuk mengetahui gambaran kemoterapi dan mengetahui berapa besar perbedaan biaya riil dengan tarif INA-CBGs pada pasien kemoterapi kanker payudara rawat inap peserta JKN di RSUD Ulin  Banjarmasin.Penelitian ini merupakan penelitian analisis farmakoekonomi dengan perspektif rumah sakit terhadap biaya medis langsung (direct medical cost) dan data diambil secara retrospektif. Objek pada penelitian ini adalah berkas keuangan rumah sakit pelayanan rawat inap dan rekam medis pasien kanker payudara peserta JKN periode bulan Januari – Oktober 2017 di RSUD Ulin Banjarmasin. Sampel yang digunakan sebanyak 259 episode perawatan. Analisis data dilakukan dengan one sample test untuk membandingkan rata-rata biaya riil dengan tarif INA-CBGs.Hasil penelitian menunjukkan gambaran kemoterapi pada pasien kanker payudara rawat inap peserta Jaminan Kesehatan Nasional di RSUD Ulin Banjarmasin periode Januari-Oktober 2017 adalah docetaxel 62,36%, siklofosfamid 52,35% dan epirubicin 40%. Besarnya perbedaan antara biaya riil dengan tarif paket INA-CBGs yaitu sebesar Rp662.143.091 (259 episode perawatan). Sedangkan rata-rata biaya riil dengan kemoterapi per episode perawatan yaitu pada tingkat keparahan I sebesar Rp.4.502.210, pada tingkat keparahan II sebesar Rp8.239.624 dan pada tingkat keparahan III sebesar Rp7.403.713.
PENGARUH RASIO KEUANGAN LIKUIDITAS DAN AKTIVITAS TERHADAP HARGA SAHAM PERUSAHAAN FARMASI YANG GO PUBLIC DI BURSA EFEK INDONESIA Marliza Noor Hayatie; Shela Puzi Dina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.554 KB) | DOI: 10.36387/jiis.v3i2.190

Abstract

Laporan keuangan merupakan informasi yang membantu investor dan pelaku pasar modal dalam mengidentifikasi keadaan suatu perusahaan. Suatu perusahaan dikatakan berhasil dan memenuhi tujuan perusahaan dengan mengukur harga saham perusahaan. Untuk mengetahui faktor yang mempengaruhi harga saham perusahaan dengan melakukan analisis tertentu.Penelitian ini dilakukan untuk mengetahui pengaruh variabel bebas yang terdiri dari likuiditas dan aktivitas terhadap variabel terikat yaitu harga saham perusahaan serta untuk mengetahui variabel bebas yang lebih dominan pengaruhnya terhadap harga saham. Dalam penelitian ini, penulis menggunakan data sekunder berupa laporan keuangan tahunan selama kurun waktu 3 (tiga) tahun yang diambil dari Indonesia Stock Exchange (IDX).Hasil penelitian menunjukkan bahwa variabel bebas yaitu likuiditas dan aktivitas tidak berpengaruh signifikan terhadap variabel terikat yaitu harga saham. Hasil penelitian ini diharapkan agar dapat membantu para investor dalam membandingkan perusahaan lain dari jenis industri yang lebih beragam.
UJI EFEK EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.) TERHADAP BAKTERI Salmonella pullorum SECARA IN VITRO A. Ika H.A. Imran A.B; Abdul Wahid Jamaluddin; Sitti Arifah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.133 KB) | DOI: 10.36387/jiis.v3i2.196

Abstract

Salmonella pullorum merupakan bakteri yang mempunyai hospes spesifik dan infeksius terhadap unggas, terutama pada anak ayam dan anak kalkun. Salah satu gejala klinis dari penyakit yang disebabkan oleh bakteri ini adalah diare. Untuk menangani masalah bakteri ini umumnya digunakan antibiotik, namun penggunaan yang berlebihan akan menyebabkan residu dan resistensi antibiotik. Untuk menghindari hal tersebut dibutuhkan alternatif pengobatan. Daun jambu biji dikenal sebagai obat tradisional diare. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun jambu biji terhadap bakteri Salmonella pullorum secara in vitro. Penelitian ini menggunakan 6 perlakuan dengan 3 pengulangan diantaranya menggunakan disk tetrasiklin sebagai kontrol positif, DMSO 10% sebagai kontrol negatif, dan variasi konsentrasi ekstrak daun jambu biji 10%, 20%, 30% dan 40%. Hasil penelitian menunjukkan adanya efek ekstrak daun jambu biji untuk menghambat bakteri Salmonella pullorum, dimana konsentrasi tertinggi (40%) memiliki efek yang paling baik.
PENGETAHUAN PASIEN TENTANG UPAYA PENCEGAHAN STROKE DENGAN TERAPI NON-FARMAKOLOGI DI POLI DALAM RSU DR. SLAMET GARUT Theresia Eriyani; Iwan Shalahuddin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.031 KB) | DOI: 10.36387/jiis.v4i1.197

Abstract

Hypertension that occurs for years can cause various problems. Effort to measure blood pressure regularly and treat it effectively, aim to prevent complications. Someone who usually smoke and let high cholesterol levels in the blood more at risk of complications. One of the complications caused by hypertension is stroke, so it is necessary to control the hypertensive patients because hypertension control can be the key prevention of stroke. This study aims to find out how the knowledge of hypertensive patients about stroke prevention efforts by way of non-pharmacologic therapy, Non-pharmacological therapies here include regular exercise, low-salt diet and lifestyle changes.The type of research is descriptive research, the polpulation in this study is all hypertensive patients who come to the Poly In dr. Slamet Garut in August 2012. The sample in this research using non probability method with accidental sampling with 25 samples. Obtained that the knowledge of hypertensive patients about the effort of stroke prevention by non-pharmacological therapy in Poli In dr. Slamet Garut from 25 respondents, have the best knowledge as much as 28.00%, knowledge enough 36.00%, have knowledge less 36.00%.Most of the respondents who studied about the knowledge of hypertensive patients about stroke prevention efforts by non-pharmacological therapy in Inner Polyclinic dr. Slamet Garut has less knowledge and enough knowledge respectively that is 36.00% (9 persons).
PENGARUH FAKTOR KARAKTERISTIK SOSIODEMOGRAFI TERHADAP PENGETAHUAN TENTANG OBAT GENERIK Nurul Mardiati; Depy Oktapian Akbar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.463 KB) | DOI: 10.36387/jiis.v4i1.200

Abstract

Kebijakan penggunaan obat generik telah menjadi salah satu implikasi yang diharapkan Pemerintah Indonesia melalui program Jaminan Kesehatan Nasional (JKN). Pasalnya melalui program JKN maka seluruh fasilitas kesehatan diwajibkan mengacu pada Formularium Nasional (Fornas) yang notabene sebagian besarnya merupakan obat generik. Jauh sebelum program JKN digulirkan oleh Pemerintah, sebenarnya Pemerintah telah mengeluarkan berbagai kebijakan guna terus mendorong peningkatan penggunaan obat generik. Akan tetapi hingga sejauh ini, penggunaan obat generik di Indonesia secara umum hanya mempunyai pasar sekitar 7% dibandingkan dengan obat branded generik. Pengetahuan yang buruk tentang obat generik dapat menyebabkan angka penggunaan obat generik pada masyarakat sulit untuk meningkat. Tujuan penelitian yaitu mengidentifikasi pengaruh faktor sosiodemografi terhadap pengetahuan tentang obat generik. Rancangan penelitiannya deskriptif-analitik. Penelitian menggunakan desain survey cross sectional. Cara pengambilan sampel dilakukan dengan proportional stratified random sampling. Cara pengumpulan datanya dilakukan dengan survey menggunakan kuesioner checklist dalam dua pilihan jawaban yaitu benar dan salah. Analisis data dilakukan dengan analisis unvariat (statistik deskriptif) dan bivariat uji t (chi-square, alternatif uji kolmogorov-smirnov). Hasil penelitian menunjukkan pengetahuan tentang obat generik dipengaruhi oleh tingkat pendidikan, tingkat penghasilan per bulan dan sumber utama informasi obat-obatan.
ANALISIS EFEKTIVITAS TERAPI ANTIRETROVIRAL PADA PASIEN HIV/AIDS RAWAT JALANDI RSUP FATMAWATI JAKARTA TAHUN 2016 Yusi Anggriani; Alfina Rianti; Jenny Pontoan; Yulwa Juwita
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.813 KB) | DOI: 10.36387/jiis.v4i1.212

Abstract

The increasing of HIV/AIDS every year become a health problem in Indonesia. Patients of HIV/AIDS should use longterm Antiretroviral (ARV) therapy of antiretroviral therapy to support the success of antiretroviral therapy. The objective of this study was to know and compare the effectivity of four ARV combination. The four ARV combination are combination A (AZT+3TC+NVP), combination B (AZT+3TC+EFV), combination C (TNF+3TC+NVP), combination D (TNF+3TC+EFV) base on increasing CD4. This study cohort-longitudinal design. Samples for this study were taken by total sampling using all data of HIV/AIDS outpatients at RS Fartmawati on 2016. The inclusion criteria were patients of (≥17 years old), received treatment of either one of the four ARV combination, and had data of CD4 from laboratory result before and 6-12 months after the treatment. Data were taken from patients medical record and analyzed with non-parametric Kruskal Wallis-test. The study results showed of 124 patients had increased the CD4 mean >100 sel/mm3 one year after the treatment. The average rate of increment of each combination of antiretroviral therapy on a median CD4 cell count of 1 year was a combination of A (73.93), combination B (70.87), combination C (48.73), combination D (55.57) and there was a significant difference in CD4 cell gain in patients taking combination A-C (p value = 0.047), combination A-D (p value = 0.041), and combination B-D (p value = 0.045) at the evaluation on 1 year. Conclusion, combination A is more effective than combination B, D and C.
FORMULASI ORALLY DISINTEGRATING TABLET (ODT) ASETOSAL DENGAN VARIASI KONSENTRASI KOMBINASI AVICE Hayatus Sa'adah; Yulistia Budianti S.; Akhmad Andy Sandra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.066 KB) | DOI: 10.36387/jiis.v4i1.216

Abstract

Acetylsalicylic acid or better known as acetosal or aspirin is a drug that has efficacy as an antiplatelet which is widely used as a drug to prevent and treat stroke. Currently acetosal is often found in many preparations, one of which is in conventional tablet preparations. Stroke sufferers really need a drug in tablet dosage form that is easy to consume, has a relatively fast duration of drug action, and with more practical drug administration. Therefore, an acetosal preparation is made in the form of Orally Disintegrating Tablet (ODT) which has several advantages, including being more practical to use because it can be consumed without using water and can be used by patients who are difficult to swallow conventional tablets. Research conducted on acetosal ODT formulation with variations in the combination concentration of Avicel PH 102 and mannitol as filler material. In this study, the physical properties of ODT acetosal were tested by varying the combination concentration of Avicel PH 102 and mannitol as a filler with a ratio of F1 = 0: 1, F2 = 0.25: 0.75, F3 = 0.5: 0.5 , F4 = 0.75: 0.25, and F5 = 1: 0. The ODT evaluation was carried out in the form of examining the weight uniformity test, hardness test, friability test, and tablet disintegrating time test. The results of the study obtained the best formula is F4 with a comparison of Avicel PH 102 and manitol 0.75: 0.25 that meets the requirements of physical properties of ODT with the average value of tablet weight uniformity test 382.5 mg ± 0.007, tablet 2 hardness test, 52 kg / cm2 ± 0.396, tablet friability test 0.53% ± 0.153, and tablet disintegrating time test 21 seconds ± 3.605.
FORMULASI DAN UJI AKTIVITAS MASKER GEL PEEL-OFF ANTIJERAWAT EKSTRAK ETANOL BAWANG DAYAK (Eleutherina palmifolia (L.) Merr) TERHADAP BAKTERI Staphylococcus aureus SECARA IN VITRO Husnani Husnani; Fitri Sri Rizki
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.686 KB) | DOI: 10.36387/jiis.v4i1.218

Abstract

Dayak union contains compounds group of alkaloids, flavonoids, saponins, tannins, glycosides, and triterpenoids which have antiacne effect. The aim of this research was to provide peel-off mask gel formula from ethanol extract of dayak union and tested its physical properties and their antibacteria activities to Staphylococcus aureus. Peel-off mask gel formulation from extract of dayak union made with various extract concentrasion which are 50 mg/ml, 75 mg/ml dan 100 mg/ml with Polyvinyl Alcohol (PVA) base as gelling agent that has adhesive properties or could make flim layer thatt could peel off after its dried. Peel-off mask gel tested its physical properties, which are organoleptic, homogenity, pH, spread capacity, drying time and viscosity. The results of physical evaluation obtained that 1st formula has calm texture, brown-red colour and unique scent of dayak union, viscosity 60.666 cps, drying time for 725,67 seconds, spread capacity 4.49 cm, and pH 5. Results of antiacne activity shows that 1st formula is more effective that 2nd and 3rd formula, with inhibition zone diameter to Staphylococcus aureus is 0.87 cm. So it conclude that 1st formula is the best formula y ist physical and can give inhibition zone on the growth of Staphylococcus aureus.
PENETAPAN KADAR FLAVONOID EKSTRAK TERPURIFIKASI UMBI BAWANG DAYAK (Eleutherine palmifolia (L). Merr) SECARA SPEKTROFOTOMETRI Siti Jubaidah; Eka Siswanto; Heri Wijaya; Muhammad Putu Aditya
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.018 KB) | DOI: 10.36387/jiis.v4i1.225

Abstract

Eleutherine palmifolia (L) Merr. is one of the plant that has function as medicine. One of the compound which much contained in ethanol extract of dayak union is flavonoid, so that could separate with purification. The aim of this study is to determine flavonoid levels in purified extract of dayak union root with various drying treatments using UV-Vis spectrophotometry and to find out which drying treatment that obtaine the highest flavonoid levels.Drying treatment of dayak union root simplicia were with direct sunlight for 6 hours (P1), dried by oven with temperature 60ºC for 6 hours (P2), dried by covered with black clothes (P3). Dayak union root simplicia extracted by maceratiin method using ethanol 70%, and purified step by step using n-hexane solvent. Flavonoid levels test of purified extract of dayak union root carried outby UV-Vis spectrophotometry method.The results of UV-Vis spectrophotometry obtained flavonoid levels of purified extract of dayak union root in dried by direct sunlight (P1) was 0.79%, dried by oven with temperature 60ºC (P2) was 1.57%, and dried by coveredwith black clothes (P3) was 1.02%. LSD test shows (P<0.05) the significant differences between flavonoid levels with different drying treatment.
PENGUKURAN KUALITAS HIDUP PASIEN HEMODIALISIS GAGAL GINJAL KRONIK DI RSUD ULIN BANJARMASIN MENGGUNAKAN INSTRUMEN EQ5D Saftia Aryzki; Maudy Namirah Raudatullis Wanda; Yugo Susanto; Mochammad Maulidie Alfiannor Saputera; Aditya Maulana Perdana Putra; Karani Karani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.29 KB) | DOI: 10.36387/jiis.v4i1.230

Abstract

Chronic renal failure is a progressive and irreversible renal function disorder in which the body's ability to fail to maintain metabolism, fluid and electrolyte balance. Chronic kidney failure can interfere with the quality of life of patients, it is necessary to measure the quality of life of patients with chronic renal failure. Measuring the quality of life of patients with chronic renal failure using the Indonesian version of the EQ5D questionnaire. The purpose of this study was to determine the quality of life of chronic renal failure hemodialysis patients in RSUD Ulin Banjarmasin using the EQ5D instrument. This study is an observational study conducted prospectively. Data was collected by filling out the EQ5D questionnaire by all patients with chronic renal failure. The population of this study were chronic renal failure patients who underwent hemodialysis in Hemodialysis Outpatient Services at Ulin Banjarmasin Hospital in June-July 2018 as many as 360 patients and a sample of 207 patients who met the inclusion and exclusion criteria using non random sampling / non-probability sampling techniques accidental sampling. Based on the research that has been done in the Hemodialysis Outpatient Hospital Ulin Banjarmasin, it was found that the average quality of life was 0.792, with a quality of life ≥ 0.792 of 69 patients (33.33%) in the category of good quality of life and quality of life ≤ 0.792 138 patients (66.66%) in the poor quality of life category.

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