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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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PENETAPAN PARAMETER NON SPESIFIK DAN SPESIFIK EKSTRAK DAUN SALAM (Syzgium polyanthum) Lina Widiyastuti; Widyasari Putranti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.324 KB) | DOI: 10.36387/jiis.v4i1.232

Abstract

Bay leaf extract is one of the traditional medicinal ingredients which is efficacious as an antihyperlipid. The quality of the extract is a parameter to guarantee the optimal therapeutic effect. Determination of non-specific and specific parameters of bay leaf extract (EDS) is needed to ensure the quality of raw materials used in hyperlipid therapy. The bay leaf extract was obtained from Bantul, Yogyakarta and macerated using 70% ethanol. EDS tested the parameters of ash content, water content, soluble ethanol extract content, water soluble extract content, acid insoluble ash content, quantitative qualitative analysis, total plate number analysis, analysis of yeast mold number, specific gravity, qualitative analysis. This study was obtained by EDS meeting the standardization of non-specific and specific parameters according to Indonesian Herbal Pharmacopoeia.
PENGEMBANGAN SEDIAAN EMULGEL MENGANDUNG MINYAK BIJI ANGGUR (Vitis vinifera L.) DAN UJI AKTVITAS ANTILUKA TERHADAP TIKUS WISTAR JANTAN (Rattus norvegicus) Sani Ega Priani; Indah Ayu Lestari; Fetri Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.718 KB) | DOI: 10.36387/jiis.v4i1.233

Abstract

Grape seed oil has wound healing activity since contains compounds such as flavonoids, polyphenols, saponins and linoleic acid. The purpose of this study is formulate emulgel containing grape seed oil with good physical characteristic and observed the wound healing activities of the oil and formulated emulgel. The research was begin with grape seed oil characterization and required HLB determination. The emulgel was made using combination Tween 80 and Span 80 as emulgator and carbomer as gelling agent with variation of oil concentration (10%, 20% and 30%). The formulation then subjected to physical evaluations including organoleptic, pH, spreadability, viscosity and rheology, sterility, and stability tests. Wound healing activity test of selected formula was done on seven groups of male Wistar rats. The emulgel containing grape seed oil with HLB value 8, has good physical, sterility, and stability characteristics. In vivo activity test showed that emulgel containing 20% and 30% grape seed oil have wound healing activity that statistically different compared with control (P<0.05) and the activity was not statistically different with marketed product (P>0.05).
PERBANDINGAN BIAYA RIIL DENGAN TARIF INA-CBG’S PENYAKIT STROKE PADA ERA JAMINAN KESEHATAN NASIONAL DI RS ISLAM SULTAN AGUNG Ken Wirastuti; Indriyati Hadi Sulistyaningrum; Erwin Budi Cahyono; Arifin Santoso; Zaki Miftahudin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.375 KB) | DOI: 10.36387/jiis.v4i1.244

Abstract

The implementation of INA CBG's system is not yet optimal because INA CBG’s rate in fact not yet fulfill hospital real cost. The purpose of this research was to compare the INA-CBG’s rate and real cost and also to look the factors affecting has difference the big real cost in patient with stroke in JKN era at Sultan Agung Islam Hospital between January 2017 and October 2017.Research using descriptive analysis, the data were analysed by Mann-Whitney test was used to compare real cost and INA-CBG’s rate. And the Mann-Whitney followed Kruskal-Wallis to determine the components of the factors affect real costs.There was a difference between the real cost and the INA-CBG's rate for hospitalization of (Rp -12,184,500) and outpatient care of (Rp -1,949,300). Factors that affect the real cost are type of nursing class (0,009), LOS (0,019) and age (0,045).The conclusion of this study is that there was a difference between the real cost and INA-CBG’s rate in patient with stroke in JKN era at Sultan Agung Islam Hospital between January 2017 and October 2017. Factors that affect the big real cost are type of nursing class, LOS and age.
AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL UMBI TAWAS UT (Ampelocissus rubiginosa Lauterb.) PADA MENCIT SECARA TOPIKAL Deka Rotama; Noor Cahaya; Sudarsono Sudarsono; Agung Endro Nugroho; Khoerul Anwar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.267 KB) | DOI: 10.36387/jiis.v4i1.245

Abstract

Tawas ut tuber (Ampelocissus rubiginosa Lauterb.) contains of flavonoid, tanin, compound and saponin which is potentially anti-inflammatory. This objective of this research is to prove by effect giving extrak ethanol tawas ut tuber about effect anti-inflammatory topical based on consideration the fold of the skin and amount of cell neutrofil to mice which induced by carageenan. Thirty mice ware divided into 6 groups. They were normal control group (palacebo gel), positive control (Voltaren®), negative control (karagenin), and testing groups with gel extract concentrations of 0,5%, 1%, and 2%. Ethanol extract of Tawas ut tuber leaf applied, after back of test animals was induced by 0,2 ml of 3% carageenan, then every hour was measured for middosal skin fold thickness during 6 hours observation. The animal’s skin was cut off to perform test at 24 hours after treatment. The neutrophils migration was observed using hematoxylin and eosin (HE) stining method. The percentage result of inhibition (%PI) ethanol extrak of tawas ut tuber with concentration 0,5%, 1%, and 2% were 20,00%; 23,51%; and 24,92% respetively. The average result of netrofil total from ethanol extrak of tawas ut tuber with concentration 0,5%, 1% and 2% were 28,28; 20,88; and 16,24 respecively. Gel 2% posesses the most effective topical anti-inflammatory. Based on the result, it can be concluded that ethanol extrak of tawas ut tuber posesses anti-inflammatory in skin oedema of back of mice induced by carageenan.
AKTIVITAS ANTIMALARIA PENGHAMBATAN POLIMERISASI HEME EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava) DAN DAUN PEPAYA (Carica papaya) M. Arifuddin; Mahfuzun Bone; Rolan Rusli; Hadi Kuncoro; Islamuddin Ahmad; Laode Rijai
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.964 KB) | DOI: 10.36387/jiis.v4i1.246

Abstract

In an effort to find new sources of medicinal plants as antimalarials based on ethnobotany knowledge from generation to generation. Therefore, tested the inhibition of heme polymerization from 70% ethanol extract of papaya leaves (Carica papaya) and Guava (Psidium guajava) leaves. The data obtained were calculated by IC50 using SPSS 22 obtained that 70% ethanol extract of Pepaya leaves (Carica papaya) and Jambu Biji leaves (Psidium guajava) had antimalarial activities of 7,914 and 8,794 mg/ml respectively and their had the potential to be developed in more research further as antimalarial.
PENGEMBANGAN MODEL BIOPSIKOSOSIAL ASUHAN KEFARMASIAN PADA KASUS PENYAKIT KRONIK: STUDI KUALITATIF TERHADAP PERSPEKTIF PASIEN PENDERITA GAGAL JANTUNG (CHF) Risya Mulyani; Herda Ariyani; Dedi Hartanto; Muhammad Anshari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (591.101 KB) | DOI: 10.36387/jiis.v4i1.251

Abstract

Congestive heart failure (CHF) is a disease that most often requires repeated treatment in the hospital. Self-care efforts allow patients to monitor and manage home syndrome, maximize well-being, reduce mortality and minimize avoidable hazards. Communication, collaboration, and patient access to bad information lead to ineffective treatment. The main problems in the care of pharmacy are improper and unsafe use of drugs and non-compliance with prescription drugs, one of which is a therapeutic regimen.. This study uses a phenomenological qualitative method in which researchers will explore the personal meaning related to biopsychosocial aspects that can affect the quality of care (pharmacy) according to the perspective of patients with CHF. The participants determined in this study were selected purposively from all patients with CHF who were treated at the Pharmacy Installation in Ulin Hospital Banjarmasin. Data analysis using the Interpretative Phenomenological Analysis (IPA) model. In this study, which explores personal meaning related to aspects of communication and collaboration that can affect the quality of care, according to the perspective of patients with congestive heart failure (CHF) in the biopsychosocial aspects, the result are: found 4 (four) themes related to results-based communication, qualitative data analysis obtained through in-depth interviews with 11 (eleven) participants, namely: (1) tangible; (2) responsive; (3) empathy; (4) assurance. And found 3 (three) themes related to collaboration based on the results of qualitative data analysis obtained through in-depth interviews with 11 (eleven) participants, namely: (1) effective communication; (2) trust; (3) feedback.
EFEK NEUROPSIKIATRIK PADA PENYALAHGUNAAN PIL ZENITH (CARNOPHEN) OLEH KULI BANGUNAN DI BANJARMASIN Mustika Muthaharah; Dewi Nurhanifah; Hendera Hendera
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.629 KB) | DOI: 10.36387/jiis.v4i1.253

Abstract

Carnophen is a muscle relaxant that works centrally, prescribed to relieve muscle spasms and pain. Recent scientific evidence confirms that carisoprodol abuse results in dangerous side effects, such as sudden psychomotor disorders and drug withdrawal resulting in hallucinations, seizures, and deaths. Abuse of this muscle relaxant in Banjarmasin was increased. The circulation is also increasingly widespread and can be bought easily and cheap prices by the public. Whereas the production permit and marketing permit for this drug have been stopped by BPOM since 2009. Weak economic communities with profane labor professions such as laborers and construction workers often consume zenith drugs for reasons not to get tired easily. This study was conducted to identify the neuropsychiatric effects that arise in zenith pill abuse (Carnophen) by construction workers in Banjarmasin. This study uses an observational design with a cross-sectional approach. This research was conducted using accidental sampling technique. Data collection was conducted in May - October 2018 using the Depression Anxiety Stress Scale - 42 questionnaire instrument (DASS 42). Data analysis was carried out with qualitative analysis of Mile's and Huberman. The results showed that from 12 research subjects for 66% stress scale experienced mild stress, 16.6% moderate stress and the remaining 16.6% normal. For anxiety scale, 8.33% experienced mild anxiety, 75% experienced moderate anxiety and 16.6% experienced severe anxiety. For depression scale, 83.3% had moderate depression and 16.6% had severe depression. The results showed that zenith abuse can cause neuropsychiatric effects such as stress, anxiety, and depression.
POTENSI ANTIOKSIDAN DARI EKSTRAK KULIT BATANG Bauhinia semibifida Roxb Haiyul Fadhli; Ainun Nurain Nurdin; Melzi Octaviani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.175 KB) | DOI: 10.36387/jiis.v4i1.257

Abstract

Telah dilakukan penelitian tentang uji aktivitas antioksidan ekstrak kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) dengan metode DPPH. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) terhadap radikal bebas. Pengujian aktivitas antioksidan menggunakan ekstrak n-heksana, etil asetat dan metanol dari kulit batang pohon kupu-kupu dan sebagai kontrol pembanding digunakan Vitamin C. Pengujian berdasarkan absorban DPPH terhadap ekstrak pada panjang gelombang 517 nm menggunakan microplate reader. Hasil penelitian menunjukkan bahwa ekstrak n-heksana kulit batang pohon kupu-kupu memiliki nilai IC50 137 µg/mL dengan nilai AAI <0,5 dan dikategorikan lemah, nilai IC50 ekstrak etil asetat 30,15 µg/mL dengan nilai AAI 1,32 dan dikategorikan kuat dan ekstrak metanol memiliki nilai IC50 sebesar 16 µg/mL dengan nilai AAI sebesar 2,5 yang dikategorikan sangat kuat. Hal itu menunjukkan bahwa ekstrak metanol kulit batang pohon kupu-kupu (Bauhinia semibifida Roxb) mempunyai aktivitas sebagai antioksidan yang sangat kuat dibandingkan dengan ekstrak lainnya.
STUDI PEMBERIAN INFORMASI TENTANG TEKNIK PENGGUNAAN METERED DOSE INHALER OLEH APOTEKER DAN TENAGA TEKNIS KEFARMASIAN DI APOTEK KECAMATAN MERTOYUDAN, KABUPATEN MAGELANG Heni Lutfiyati; Tiara Mega Kusuma; Septi Wardani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.84 KB) | DOI: 10.36387/jiis.v4i2.258

Abstract

Asthma is a serious health problem and can attack all age groups. Inhalation of drugs is the most important route in the management of asthma. The purpose of this study was to find out the description of the provision of information about the technique of using Metered Dose Inhalers by pharmacists and pharmacy technician at the Mertoyudan District pharmacy, Magelang District. This research is a descriptive study using the investigation research approach that is gathering information related to the provision of information on the use of Metered Dose Inhaler techniques by pharmacists and pharmacy technicians by means of investigation. The data obtained is then analyzed and made conclusions. The variables in this study are providing information about the use of Metered Dose Inhalers by pharmacists and pharmacy technicians. Data collection was carried out in February 2018. The population in this study were all pharmacists and pharmacy technicians in the Mertoyudan District, Magelang District. The sample in this study is Pharmacists and Pharmacy technicians who practice in the pharmacy of the Mertoyudan District Region, Magelang District. Observations made by researchers in Mertoyudan District with a total of 15 pharmacies, obtained 40% of pharmacies available inhaler drugs and 60% of pharmacies are not available because rarely patients buy and the price of drugs is expensive. The results showed that from 9 stages of using Metered Dose Inhalers, all respondents demonstrated the opening and closing stage of the inhaler and press the canister and only 6.67% gave information slowly exhaling until there was no remaining air to be exhaled. The conclusion of the pharmacist who provided complete information about the technique of using inhalers was 6.67%.
KADAR TOTAL ALKALOID, FENOLAT, DAN FLAVONOID DARI EKSTRAK ETIL ASETAT HERBA SURUHAN (Peperomia pellucida [L] Kunth) Islamudin Ahmad; Maryono Maryono; Abdul Mun'im
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.745 KB) | DOI: 10.36387/jiis.v4i2.261

Abstract

The study aimed to determine the total alkaloid, phenolic, and flavonoid content of ethyl acetate extract of Peperomia pellucida (L.) Kunth herbs, especially the herb was obtained from oil palm plantations in Baras, Nort Mamuju District, West Sulawesi Province. The sample was macerated using n-hexane then was followed with ethyl acetate. Determination of total phenolic content was performed using Folin-Ciocalteu reagent, and its absorbance was measured at 750 nm wavelength with gallic acid as a standard. Determination of total flavonoid content was conducted using AlCl3 reagent, and the absorbance was calculated at 415 nm wavelength using quercetin as a standard. Determination of total alkaloid content was calculated against the equal piperine at a wavelength of 435 nm using Dragendorff reagent. Based on the results of determination on ethyl acetate extract of Suruhan herbs was obtained the total phenolic content of 178.768+10.63139 mg/gram, total flavonoid content of 1.397+0.004509 mg/gram, and total alkaloid content of 0.615+0.155885 mg/gram. These results are preliminary data of further studies to the isolation of the targeted compounds and the utilization purposes as a raw material of herbal medicine.

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