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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

JIIS
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Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

ISSN : 2502647X EISSN : 25031902 DOI : https://doi.org/10.36387/jiis

Core Subject : Health,

Medicine & Pharmacology

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 429 Documents

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FORMULASI KRIM EKSTRAK ETANOL BETATAS UNGU (Ipomoea batatas L.) Sulistianingsih Sulistianingsih; Ravika Ramli; Herlando Sinaga
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

This research aims to determine the best formulation from the cream of a purple sweet potato (Ipomoea batatas L.) ethanol extract. This type of research is descriptive with a laboratory experimental approach. Samples of purple sweet potato (Ipomoea batatas L.) used were from Arso 3 Keerom Regency. The extraction method used is the maceration method using 70% ethanol solvent. In this research, ethanol extract of purple sweet potato was made a cream with three formulas using variations of stearate acid concentration, namely: F1-6%, F2-12%, and F3-18%. The cream will be evaluated including the organoleptic test, pH test, a homogeneity test, irritation test, accelerated stability test. The results showed that the best cream formulation for ethanol extract of purple sweet potato was F3 with variations in stearate acid concentration (18%). Cream F3 has a purplish red color, has a distinctive odor, thick, homogeneous consistency, pH 7, and does not change after storage for Ãƒâ€šÃ‚Â± 3 weeks.

KARAKTERISASI FRAKSI TERAKTIF SENYAWA ANTIBIOTIK ISOLAT KP 13 DENGAN METODE DENSITOMETRI DAN KLT-SEMPROT Alfian Syarifuddin; Nanik Sulistyani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Exploration of microorganisms Actinomycetes can produce antibiotic compounds. One of the bacteria that can produce antibiotic compounds is the KP13 bacterial isolate. The purpose of this study was to determine the character of the fraction of KP13 isolates using the densitometry method and the spray / colouring reaction of thin layer chromatography elution. The wavelengths used for densitometry 210 nm and spray reagents used include ninhydrin, Dragendorff, 2,4-dinitrophenyl hydrazine (2,4-DNPH), and sulfuric acid anisaldehyde. The results of the study using densitometry at a wavelength of 210 nm showed the highest peak chromatogram at Rf 0.78. The compound that is thought to be responsible for the Rf value of 0.78 has the characteristics of Terpenoid compounds, alkaloids, and carbonyl.

DETEKSI CEPAT GEN INVA PADA SALMONELLA ATCC DENGAN LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) Soni Muhsinin; Rahma Ziska; Maria Martina Sulastri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Salmonella spp. is a bacterium that causes typhoid salmonellosis (typhoid fever). These bacteria enter through the oral route, usually by contaminating food and drinks. Salmonella spp. has an invA gene that causes pathogenicity in humans. The culture method is used as a gold standard to detect Salmonella spp. However, this method requires infrastructure and is laborious. The purpose of this study is to develop detection of Salmonella spp. using the Loop-Mediated Isothermal Amplification (LAMP) method. The stages of the study began with the primary design of LAMP, Salmonella ATCC culture, DNA Isolation of Salmonella ATCC culture, and Salmonella ATCC LAMP Optimization. Primary LAMP that has been designed consists of three pairs. Salmonella ATCC DNA that has been isolated has a concentration of 4,5 ng/ul. The LAMP method shows positive results in detecting the InvA gene in Salmonella ATCC. Positive results are indicated by fluorescence in Salmonella ATCC DNA samples, whereas the negative results are shown in the absence of fluorescence in nuclease free water. The conclusion from the research that has been done, LAMP method can detect InvA gene in Salmonella ATCC.

SINTESIS DAN UJI TOKSISITAS SENYAWA 1-(2,4-DIKLOROFENIL)-3-(3,4-DIMETOKSIFENIL)PROPENON Husnul Khatimah; Agung Rahmadani; M. Arifuddin; Rolan Rusli
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Chalcone has been widely reported to have various activities such as cytotoxic, antioxidant, antibacterial, and others. Synthesis becames the right way to get chalcone because it can produce much yield of chalcone and can be varied in accordance with the desired structure. The compound of 1-(2,4-dichlorophenyl)-3-(3,4-dimethoxyphenyl)propenone was synthesized by conventional method for 6 hours using a 40% NaOH catalyst with a yield of 90.87%. The toxicity test of 1-(2,4-dichlorophenyl)-3-(3,4-dimethoxyphenyl)propanone was done by Brine Shrimp Lethality Test method (BSLT). The results of the test showed that the 1-(2,4-dichlorophenyl)-3- (3,4-dimethoxyphenyl)propenone has toxicity value LC50 613.05 ppm.

PENGARUH PEMBERIAN SALEP EKSTRAK KUNYIT KUNING (Curcuma longa Linn) TERHADAP PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH (Rattus norvegicus) Muthia Milasari; Abdul Wahid Jamaluddin; Yuko Mulyono Adikurniawan
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Turmeric is one of the herbal contents substancials that believed help wound healing process. Scientifically, turmeric has been shown to have an anti-inflammatory and choleretic effect. The curcumin compound has potential effects as antimicrobial and antioxidant that can accelerate the re-epithelialization and migration of cells such as myofibroblast, fibroblasts and macrophages. Those are compounds for wound healing. The aims of this study is to know the effect of yellow tumeric extract oinment in wound healing based on the time of wound close and morphological changes are compared with the controls. This study was carried out by experimental test. The experimental animals were divided into 5 groups, each group consisted of 5 animals. Each group is treated, among others by giving 10%, 20%, and 30% yellow turmeric extract ointment (treatment groups), povidone iodine 10% ointment (positive control) and ointment base (negative control). The rats were given an incision in the back of the vertebrae with square pattern around Ãƒâ€šÃ‚Â±2cm to fascia. Yellow turmeric extract ointment was applied to rat wounds 2 times a day and observed daily from day 1 to day 14. Data were analyzed using ANOVA (analysis of variance). The results showed a significant difference in 5 groups (P< 0.05). There were differences in the results of the study between the treatment group (10%, 20% and 30% yellow tumeric extract ointment), positive control (povidone iodine 10% ointment) and negative control group (ointment base) which showed a faster treatment group to heal wounds compared the control group. The study reveals that 10% yellow turmeric extract ointment is best in accelerating wound healing.

MIKROENKAPSULASI EKSTRAK BUAH BUNI (Antidesma bunius L.) MENGGUNAKAN MALTODEKSTRIN DENGAN METODE SPRAY DRYING Michrun Nisa; Agustina Ma'tang Parinding; Abdul Halim Umar; Nur Khairi; Astuti Amin; Maulita Indrisari; Wahyu Hendrarti; Andi Nur Aisyah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Buni fruits (Antidesma bunius L.) is one of the plants that contain anthocyanin dyes. This study aims to create and characterize buni fruit extract microcapsules containing anthocyanin using spray drying method. The coating materials used were 5%, 7%, 5%, 5%, and 5% of the maltodextrin. Buni fruit was determined by the total content of anthocyanin and microcapsules obtained by organoleptic characterization, microencapsulation efficiency, particle morphology, and particle size distribution. The total content of anthocyanin from buni fruit extract is 18.14 mg/100g. Microcapsules obtained by variation concentration of pink maltodextrin typical of buni fruit weighing 2.7 g, 3.3 g, 2.3 g, obtained the value of EEC (%) 50, 55, and 59, respectively, on the appearance of SEM form spheries and on PSA particle size distribution 2.5 ÃƒÅ½Ã‚Â¼m, 2.1 ÃƒÅ½Ã‚Â¼m, 2.6 ÃƒÅ½Ã‚Â¼m.

HUBUNGAN ANTARA WAKTU TUNGGU PELAYANAN RESEP TERHADAP TINGKAT KEPUASAN PASIEN DI PUSKESMAS KELAYAN DALAM Amaliyah Wahyuni; Mochammad Maulidie Alfiannor Saputera; Novia Ariani; Anna Khumaira Sari; Mawaddah Mawaddah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Prescription service is one of the pharmaceutical at public health center. One of the minimum standards of pharmacy service at public health center is the waiting time. The prescription waiting time is the patient's waiting time for prescribing medicines that start from prescription received at TTK until the patient is finished receiving the medicines. A great service in waiting time can affect patient satisfaction, so the public health center should be able to control the service time to achieve patient satisfaction.The purpose of this research is to know the illustration of prescription waiting time and the levels of patient satisfaction, also correlation between prescription waiting time with patient satisfaction at public health center Kelayan Dalam.The type of research is descriptive analytic. The Sample is done by non probability sampling using purposive sampling method and statistical data analysis technique is done by using SPSS 17.0 that is Chis Square test. The research was conducted from May to June in 2018, with a total of 178 respondents. Data collection was done with observation sheet for prescription waiting time and questionnaire about patient satisfaction which has been done with valid and reliable test.The results showed that of 178 respondents in the illustration of the waiting time for non-concoction prescription is about 4,25 minutes and for the concoction prescription is about 7,71 minutes, the results are in compliance with the standards set by the head of the public health center, the results of research in satisfaction level with the percentage of 74, 85% are in the satisfied category. And statistic result show sig value 0,001 <0,05 that there is a significant correlation between prescription waiting time and patient satisfaction level so that if the prescription waiting time can be faster then the feeling of satisfaction in patient can be higher too.

KARAKTERISASI DAN SKRINING FITOKIMIA SIMPLISIA DAUN SELUTUI PUKA (Tabernaemontana macracarpa Jack) Fitri Handayani; Anita Apriliana; Hellen Natalia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Selutui puka (Tabernaemontana macrocarpa Jack) is a plant that is efficacious for treating tumor diseases and blisters. Simplicia is said to be of high quality if it meets the simplicia requirements. The initial process to find out the quality of simplicia is characterization. The study aims to determine the specific, non-specific characteristics and content of chemical compounds.This research is non experimental. The research starts from sampling, determination, making simplicia, characterization which includes macroscopic test, microscopic test, determination of moisture content, soluble ethanol extract content, water soluble extract content, moisture content, ash content, acid insoluble ash content and phytochemical screening. Data were analyzed using descriptive methods.Specific characteristics in the macroscopic and organoleptic tests showed long round leaves, pinnate leaf bones, spiky rounded leaf tips, rounded base of leaves, flat leaf edges, thick leaf flesh, dark green color, leaf width of 4.5 cm long, 12.5 cm long. The powder is dark green, aromatic and has a bitter taste. Microscopic tests include cover hair, vessels, bundles of stairs, upper epidermis and lower epidermis with bidiastic type stomata, 12% soluble ethanol, 15% water soluble extract. Non-specific characteristics consisted of 8% moisture content, 6.51% ash content, acid insoluble ash content 0.246%. The results of phytochemical screening contain alkoloid, flavonoids, tannins, saponins and steroids.

PEMANFAATAN MEDIA SOSIAL UNTUK MENINGKATKAN KEPATUHAN MINUM OBAT PASIEN DIABETES MELITUS RAWAT JALAN DI RSUD ULIN BANJARMASIN Yugo Susanto; Fahma Lailani; Riza Alfian; Leonov Rianto; Dwi Rizki Febrianti; Saftia Aryzki; Erna Prihandiwati; Nurul Shadika Khairunnisa
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Diabetes mellitus is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormal insulin secretion, insulin action or both. WHO predict that by 2030 the number of patients diabetes mellitus in Indoneisa will reach 21,3 million. Patien t compliance is indispensable for achieve theapeutic success. The purpose of this study was to determine the level of medication adherence and differences of the level in medication adherence for outpatient diabetes mellitus patients before and after giving intervestion using sosial media. The sosial media use is whatsapp.The study was conducted with a quasi-experimental design with prospective data taking during period July to August 2018. The subjects who followed study from the beginning to the end of the study were 24 patients with intervention using whatsapp sosial media. Exclusion criteria patients were patients with deaf, illierate and patienets wiht high leves of adherence. Collecting data by interviewing filing out the MARS compliance questioning pre and post intervention on whatsapp sosial media.Based on the result of the study of the level of adherence to medication after intervention were high adherence 83,33% and moderate adherence 16,67%. That was significant adherence difference (p=0,000) of the medication adherence before (22,04Ãƒâ€šÃ‚Â±1,57) and after (24,83Ãƒâ€šÃ‚Â±0,38). The average change is 2,79Ãƒâ€šÃ‚Â±1,19. The result of the study concluded that the interventions using sosial media in patients with diabetes mellitus useful can change pasient adherence in taking medicine. That is indicated by a increase in adherence medication patients (p<0,005).

UJI AKTIVITAS EKSTRAK ETANOL KULIT ARI BUAH JENGKOL (Pithcelobium jiringa) SEBAGAI BIOLARVASIDA NYAMUK (Aedes aegypti L.) Noverda Ayuchecaria; Nida Munirah; Amaliyah Wahyuni; Eka Kumalasari; Ratih Pratiwi Sari; Siska Musiam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Larvasida is still the first line in the prevention of Dengue Hemorrhagic Fever (DHF) disease caused by Aedes aegypti L. mosquitoes. Indonesia itself as a tropical country has many beneficial plants, one of which is Pithcelobium jiringa pericarp. Until now, the use of pericarp is still lacking even though jengkol fruit peels contain secondary metabolites such as flavonoids, saponins, tannins and triterpenoids, which have larvacidal effects. The purpose of this study was to determine the activity of ethanol extract of Pithcelobium jiringa pericarp as biolarvasida of Aedes aegypti L. mosquitoes from LC50 values. The treatment concentration used in this study was concentrations of 10%, 30%, and 50%. Temephos 1% is used as a positive control. The concentration was then tested on 20 Aedes aegypti L. larvae. The results showed that there was a treatment effect (sig <0.05) on the number of larval deaths, which from the results of Tuckey's analysis showed that 30% and 50% concentrations and 1% Temephos showed significant differences in the number of test larvae deaths. The results showed that the extract was effective as biolarvasida of Aedes aegypti L. mosquitoes. The results of probit analysis showed LC50 extract to Aedes aegypti L. larvae was 20.4716% which is a low toxin group in aquatic environments.

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Contact Name Siska Musiam

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Editorial Address Jl. Flamboyan III/7c Kayu Tangi 70123 Banjarmasin Kalimantan Selatan

Location Kota banjarmasin, Kalimantan selatan INDONESIA

Abstract

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Contact Name
Siska Musiam

Contact Email
siska@stikes-isfi.ac.id

Phone
+62511-3301610

Journal Mail Official
jiis@stikes-isfi.ac.id

Editorial Address
Jl. Flamboyan III/7c Kayu Tangi 70123 Banjarmasin Kalimantan Selatan

Location
Kota banjarmasin,

Kalimantan selatan

INDONESIA