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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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KARAKTERISTIK PROTEIN IKAN SEPAT RAWA (Trichopodus thricopterus) ASAL KALIMANTAN SELATAN YANG BERPOTENSI SEBAGAI ANTIDIABETES Karunita Ika Astuti; Fitriyanti Fitriyanti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.801 KB) | DOI: 10.36387/jiis.v5i1.392

Abstract

/KgBB berbeda signifikan dengan kontrol negatif dan tidak berbeda signifikan dengan kelompok glibenklamid yang memiliki persentase penurunan kadar gula sebesar 37,91%. Kata kunci: Antidiabetes, Tepung ikan Sepat Rawa, Kalimantan. ABSTRACT Diabetes treatment using fish is still not much developed. High protein potential in fish as antidiabetic where amino acids such as lysine arginine, leucine, isoleucine and several other amino acids can increase insulin action by increasing energy in the cell metabolism cycle. The purpose of this study is to develop the Kalimantan Sepat Swamp fish as an alternative therapy in patients with diabetes mellitus. Testing the characteristics of protein samples is carried out qualitatively in the form of biuret, ninhydrin, milon, fohl, xantoprotein, and sakhaguchi and testing the antidiabetic potential using test animals in the form of mice and measured levels of mice blood sugar using a glucometer. The treatment group was divided into 5 groups: positive control using Glibenclamide at a dose of 0.5 mg / kgBB, negative control NaCMC, fish meal 100 mg / KgBB; 200 mg / kg, and 300 mg / kg. The results of protein characteristics test showed positive swamp fish meal contained alpha amino acids, tyrosine, amino acids containing sulfur, cyclic, and arginine. In testing the antidiabetic potential of swamp fish meal the results showed that a dose of 300 mg / KgBB was the dose that had the best antidiabetic activity with a percentage decrease of 21.84%, followed by a dose of 200 mg / KgBB of 21.11% and a dose of 100mg / KgBB 6.33%. Antidiabetic activity of swampy fish meal 300 mg / KgBB differ significant with negative control and did not differ significantly from the glibenclamide group which had a decreased percentage of sugar by 37.91%.
PENGARUH ALARM MINUM OBAT (AMINO) UNTUK MENINGKATKAN KEPATUHAN MINUM OBAT PASIEN HIPERTENSI Yusmaniar Yusmaniar; Yugo Susanto; Surahman Surahman; Riza Alfian
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.051 KB) | DOI: 10.36387/jiis.v5i1.395

Abstract

According to data from Riskesdas 2018 there was an increase in the prevalence of hypertension in Indonesia from 25.8% in 2013 to 34.1% in 2018. Inadequacy in taking medicine is one of the factor contributed. This research discusses the importance of the application of taking medication alarms for consultation taking medication and hypertension patients' blood pressure. The study was conducted using a quasi-experimental two group pretest posttest design. Observed data are the level of adherence and blood pressure. The study was conducted at 2 Banjarmasin Puskesmas. Data collection collected in the period August - October 2019. Research data were obtained by filling in the MARS questionnaire, while blood pressure data was taken from medical records. This study involved 25 samples each in the control and intervention groups. The intervention given was in the form of installing medication alarm in sample smartphone. The Wilcoxon Test to determine differences in the average category of level of adherence, and blood pressure samples at the beginning and end of the study. In the pre study 100% of the sample intervention group were at moderate medication adherence rates and in the post study it changed to 40% at moderate medication adherence levels and 60% at high medication adherence levels. Statistical test results show a significant increase in medication adherence. Systolic and diastolic blood pressure in the intervention group also experienced a significant decrease (p <0.05). The results of the study in the control group showed no increase in medication adherence and no significant decrease in blood pressure.
GAMBARAN TINGKAT KEPUASAN PASIEN BPJS RAWAT JALAN TERHADAP PELAYANAN KEFARMASIAN DI INSTALASI FARMASI RSD IDAMAN BANJARBARU TAHUN 2019 Depy Oktapian Akbar; Gusti Dewi Handayani; Aristha Novyra Putri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.178 KB) | DOI: 10.36387/jiis.v5i1.396

Abstract

Pharmaceutical services are health services that have an important role in realizing a good quality health. Hospitals as health services must pay attention to the quality of services, especially after the implementation of the national health insurance program (BPJS). The service quality of service can be assessed by description the patient satisfaction level. This study aims to description the patient satisfaction level of BPJS outpatient towards pharmaceutical services in the Idaman Banjarbaru Hospital. This research was a non-experimental research with descriptive research by using cross-sectional approach. The study was conducted at the Pharmacy Installation of Idaman Banjarbaru Hospital in May - June 2019. Samples were selected by purposive sampling on 100 respondents of BPJS outpatients. The research instrument was in a questionnaire form, to measure the five dimensions of patient satisfaction. The description results of the satisfaction level of BPJS outpatients towards pharmaceutical services in the Pharmacy Installation of Idaman Banjarbaru Hospital seen from the 5 dimensions of service that were obtained an average score of reliability at 86.30%, Responsiveness at 84.45%, Assurance at 84.75% , Emphaty at 85.75% and Tangible at 84.70%. The Conclusion is the patient felt very satisfied with the pharmaceutical services at the Pharmacy Installation with an average value of all dimensions at 85.19%.
AKTIVITAS ANTIBAKTERI EKSTRAK DADANGKAK (Hydrolea spinosa) TERHADAP BAKTERI Bacillus subtilis, Staphylococcus aureus DAN Escherichia coli Putri Vidiasari Darsono; M. Fajriannor T. M.
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.889 KB) | DOI: 10.36387/jiis.v5i1.398

Abstract

Hydrolea spinosa are one of the plants that grow in swamp habitat. This plant is used by the loksado hill dayak community in the area Hulu Sungai Selatan as a cure for malaria, coughing up blood, medicine for sores and ulcers and mosquito repellent. The phytochemical content of H. spinosa leaves include tannins, steroids, flavonoids, and alkaloids. Bacillus subtilis, Staphylococcus aureus is gram positive bacteria while Escherichia coli is gram negative bacteria. This study aims to determine the Antibacterial Potential of Dadangkak Ethanol Extract (Hydrolea spinosa) Against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli as local plants in South Kalimantan. The method used is disk diffusion, the stages of this research are starting from sample preparation, extraction, antibacterial screening, sterilization and media making, rejuvenation and making of bacterial suspensions, making variable concentration stock, and antibacterial test. Positive control using Amoxicillin 25 mcg and negative control using 20% ​​DMSO. Based on the results of the average inhibition zone of ethanol extract of dadangkak leaves on Bacillus subtilis with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml which is 4.3 mm, 4 mm, 5 mm, in Staphylococcus aureus with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml are 3mm, 4.6mm, 6.3mm while Escherichia coli with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml are 2.3mm, 3mm, 3.3mm. This shows that dadangkak leaf extract has antibacterial activity on gram-positive and gram-negative bacteria.
UJI AKTIVITAS EKSTRAK KENTAL ETANOL PANDAN HUTAN JENIS BARU (Freycinetia sessiliflora RIZKI) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Fitri Sri Rizki; Ade Ferdinan
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (174.054 KB) | DOI: 10.36387/jiis.v5i1.403

Abstract

A new species of the pandanus (Freycinetia sessiliflora Rizki) is one species found in the year 2015 on Passi Mount, West Kalimantan. The researchers found the pandanus new species which is very different from other pandanus. The results of skrinning phytochemical leaves of the pandanus (Freycinetia sessiliflora Rizki) containing a compound of a secondary metabolite namely alkaloid , flavonoid , terpenoid-steroid , saponin , phenol and tannin. Based on secondary metabolite compounds which done research to test the activity of the pandanus extract bacteria Staphylococcus aureus. Plant extracts pandanus in get maceration with a solvent use of ethanol to achieve an extract will be used to test the activity of obstruent against bacteria Staphylococcus aureus by using the Then it will be the measurement of clear zone formed about paper discs .Analyze by anova data in one direction with the levels of trust 95 %. Based on the research done an obstruent extracts the results of a new species of pandanus against bacteria staphylococcus aureus with an average diameter obstruent concentration 5% of 10,86, mm the concentration of 10 % of 11,46, mm the concentration of 15 % of 11,8, mm the concentration of 20% of 12,24 mm and the highest 25% of 12,9 mm.
VALIDASI METODE KROMATOGRAFI LAPIS TIPIS (KLT)-DENSITOMETRI UNTUK PENETAPAN KADAR β-KAROTEN DALAM TABLET KUNYAH EKSTRAK Spirulina platensis Siti Fatmawati Fatimah; Citra Ariani Edityaningrum; Wihasty Nur Istyqomah; Ibnu Gholib Gandjar; Laela Hayu Nurani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.6 KB) | DOI: 10.36387/jiis.v5i1.404

Abstract

Analytical Validation Method to determine β-carotene in the Spirulina platensis extract chewable tablets need to be done to ensure the quality. The purpose of this study is to prove the validity of the TLC-Densitometry method for determining the levels of β-carotene in the Spirulina platensis extract chewable tablets. Validation of the analysis method was carried out using standard β-carotene and spirulina chewable tablets in ethyl acetate solvents including specificity, linearity, repeatability precision, intermediate precision, limit of detection and limit of quantitation with stationary phase of silica gel 60 F254 and mobile phase of acetone: ethyl acetate (1: 1 v/v) using the TLC method, then quantitative analysis was carried out with a Densitometer at a wavelength of 453 nm. The results showed that the TLC-Densitometry method was linear with an r value of = 0.9938, having a repeatability precision with RSD 1.89%, intermediate precision with an RSD value of 2.401%, an LOD of 0.159 mg/mL and an LOQ of 0.531 mg/mL, and the specificity showed that this method is not specific to β-carotene compounds and the accuracy does not indicate a recovery value. Based on these results it can be concluded that the TLC-densitometry method is invalid for the determination of β-carotene levels in the Spirulina platensis extract chewable tablets.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN DAN KULIT BATANG KALANGKALA (Litsea angulata) ASAL KALIMANTAN SELATAN Eka Fitri Susiani; Revita Saputri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.615 KB) | DOI: 10.36387/jiis.v5i1.406

Abstract

Antioxidants have an important role in inhibiting free radicals that trigger oxidative stress cells that cause degenerative diseases. Kalangkala (Litsea angulata) is a typical plant of Borneo which may have antioxidant activity. This study aims to determine the antioxidant activity of ethanol extract of leaves and stem bark of Kalangkala (L.angulata) from South Borneo. Extracts were investigated for antioxidant activity qualitatively and quantitatively using 2,2-diphenyl-1-picrylhydrazyl (DPPH). Qualitatively, the results of antioxidant assays from ethanol extract of leaves and stem bark showed that there were yellow spots with a purple background on the TLC plate. Quantitatively, the ethanol extract of Kalangkala leaves obtained IC50 values of 152.39 ppm, while the ethanol extract of Kalangkala stem bark obtained IC50 values of 85.33 ppm. Thus, it can be concluded that the leaves and stem bark of Kalangkala (L.angulata) have antioxidant activity.
STUDI EFEKTIVITAS REDUKSI KADAR FORMALIN PADA TAHU DENGAN PERENDAMAN AIR KUNYIT, AIR CUKA DAN AIR GARAM DALAM UPAYA PENYEDIAAN PANGAN AMAN Kadek Duwi Cahyadi; Agustina Nila Yuliawati; Gusti Ayu Dewi Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.403 KB) | DOI: 10.36387/jiis.v5i1.409

Abstract

Tofu is one type of food made from soybeans which is widely consumed and even favored by the people of Indonesia. Based on research conducted in Manado City Health Market in 2017, 92.86% of white tofu sold in the market positively contains formalin. The high content of formalin will poison the body, cause stomach irritation, allergies, are carcinogenic (causing cancer) and are mutagenic (causing changes in cell function). In this research, a simple way to reduce formalin levels in tofu will be developed, namely immersion with turmeric water, vinegar, and salt water in formalin tofu samples (simulated samples). Optimization will be carried out on the soaking time to get the most optimal conditions to reduce the levels of formalin in tofu. The simulation sample was treated with turmeric water, vinegar and salt water for 15, 30, and 60 minutes and then tested with fehling and tollens reagents. Quantitative tests were also performed using UV-VIS spectrophotometry using chromatrophic acid reagents. Qualitative test results showed a decrease in formalin levels after soaking with turmeric water, vinegar and salt water for 60 minutes. Quantitative test results, immersion of turmeric water, vinegar and salt water for 60 minutes showed a decrease in formalin concentrations by 22.56%, 25.54% and 55.33%.
BIAYA MEDIK LANGSUNG PASIEN STROKE NON-HEMORAGIK KELAS PERAWATAN 3 RSUD K.R.M.T WONGSONEGORO SEMARANG Hanik Utaminingrum; Fef Rukminingsih
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.256 KB) | DOI: 10.36387/jiis.v5i1.413

Abstract

The most common stroke in Indonesia is non-hemorrhagic stroke (SNH), which occurs in 85-87% of all stroke cases. Stroke requires expensive costs because the process of treating stroke patients is done in a long time and routine. SNH patients who go to K.R.M.T Wongsonegoro Hospital Semarang every year increase in number. This study aims to determine the amount of direct medical costs for treatment class 3 SNH patients at K.R.M.T Wongsonegoro Hospital Semarang and their compliance with Indonesian Case Based Groups (INA-CBG) rates. This study is a pharmacoeconomic study with a hospital perspective on direct medical costs using retrospective data for the October-December 2018 period. The object of this study is the medical record and billing data from the Hospital Information and Management System SNH patients participating in the National Health Insurance treated in treatment class 3. Based on the results of medical record tracking and billing data for SNH patients, 64 patients were known. The number of female patients was 41 people (64.06%). Most of the patients (93.75%) were over 45 years old. A total of 27 patients included in the category of mild SNH and 37 patients in the category of moderate SNH. The average direct medical cost for SNH patients in the mild category is IDR 3,005,019 ± 1,010,931, - and the compliance with INA-CBG’s tariff was 92.59%. The average direct medical cost for SNH patients in the moderate category is IDR 3,602,846 ± 1,259,001 and the compliance with INA-CBG rates of 94.59%.
PENENTUAN KADAR FENOLIK TOTAL EKSTRAK ETANOL 96% DAUN TERAP (Artocarpus odoratissimus Blanco) DENGAN METODE SPEKTROFOTOMETRI VISIBEL Anna Khumaira Sari; Noor Aisyah; Erna Prihandiwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (415.444 KB) | DOI: 10.36387/jiis.v5i1.417

Abstract

Terap leaf (Artocarpus odoratissimus Blanco) is a plant that contains flavonoids which are phenolic groups. These compounds are effectively used as natural antioxidants. Antioxidants function to reduce the speed of lipid peroxidation by giving electrons to free radicals, can make normal molecules. Phenol compounds also have bacteriosid, antihelmintic, analgesic, anti-inflammatory, antimicrobial, anticancer and degenerative diseases. The purpose of this study was to determine the total phenolic levels contained in the terap leaf plants. The terap leaves were obtained from Amuntai City, Hulu Sungai Tengah which were selected based on inclusion and exclusion criteria. Phenolic compounds in terap leaves were extracted using maceration method using 96% ethanol solvent. Qualitative testing of terap leaf was determined using FeCl3 reagent, determination of terap leaf compounds was expressed with gallic acid equivalence value. The method used is Visible Spectrophotometry with Folin ciocalteau reagents. The concentrations used in linear regression curves are 5, 10, 15, 20, 25 and 30µg / mL. Qualitative test results obtained the terap leaf extract positive containing phenolic compounds with marked changes in yellow to green. Based on quantitative test results obtained operating time at minute 1 and the maximum wavelength obtained is 762 nm. Linear regression obtained by y = 0.0213x + 0.117. The value of total phenolic content obtained in the terap leaf extract was 10.56% w / w.

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