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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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FORMULASI EKSTRAK ETANOL DAGING BUAH PEPAYA (Carica papaya LINN) DALAM BASIS LOTION, UJI SIFAT FISIK DAN NILAI SPFNYA Febrianika Ayu Kusumaningtyas; Iis Wahyuningsih; Nining Sugihartini
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.562 KB) | DOI: 10.36387/jiis.v5i1.424

Abstract

Human skin is intensely exposed to the factors that risk causing irritation and damage. Carica papaya Linn is a fruit which rich in phenolic and flavonoids compounds that has an activity to ward off Ultraviolet Radiation (UVR). This research aims to formulate lotion with 1% (F1), 3% (F2) and 5% (F3) of concentration of papaya fruit extract, then tested the physical properties including pH test, viscosity, flow properties, spreadability, adhesivity and activity test as a sunscreen to determine the SPF value. Results showed that the presence of extracts and increased of its concentrations affected the spreadability, viscosity of the lotion and the value of SPF significantly, but had no significant effect on adhesivity, pH and physical stability. It can be concluded that papaya fruit extract lotion meets the dosage requirements, physically stable and has activity as a sunscreen.
OPTIMASI PRODUKSI ANTIBAKTERI CAIRAN KULTUR ISOLAT BAKTERI (ISOLAT Te234) TERHADAP BAKTERI Escherichia coli DAN Staphylococcus aureus Sandi Kurniawan; Alfian Syarifuddin; Herma Fanani Agusta; Missya Putri Kurnia Pradani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.542 KB) | DOI: 10.36387/jiis.v5i2.449

Abstract

Antibiotics are metabolic products produced by certain microorganisms that can also damage other microorganisms. About 22,000 secondary metabolites in the form of antibiotics are produced by microbes, 70% are produced by actinomycetes, 20% by fungi, 7% Bacillus spp. and 1–2% by other bacteria. This research was conducted to determine the optimal time for bacteria to produce antibacterial which can inhibit the growth of Staphylococcus aureus and Escherichia coli. The method used is the well method with a diameter of 6.00 mm wellbore. The test results obtained, isolates of Te234 can produce optimal antibacterial which can inhibit the growth of Staphyloccus aureus bacteria on the 13th day with inhibition zone diameter of 16.00 ± 4.00mm against Escherichia coli bacteria on the 14th day with inhibitory zone diameter of 15, 33 ± 1.15mm so that it can be used as a determinant of the incubation time to produce antibacterial compounds. The TE 234 isolates are able to produce antibiotics that have the potential for the Staphylococcus aureus bacteria optimally on the 13th day, while on Escherichia coli on the 14th day
FORMULASI GRANUL EFFERVESCENT EKSTRAK ETANOL 90% BUAH LABU AIR (Lagenaria siceraria) SEBAGAI ANTIOKSIDAN DENGAN VARIASI GAS GENERATING AGENT Dyera Forestryana; Yunitha Hestiarini; Aristha Novyra Putri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (567.837 KB) | DOI: 10.36387/jiis.v5i2.457

Abstract

Water pumpkin (Lagenaria siceraria) is a vegetable that contains secondary metabolites that are beneficial to health. Its use as a vegetable is less attractive to the people so that to increase its utilization, dosage forms are made that can attract public interest, one of which is effervescent granules. Effervescent granules are the most popular dosage form because they can serve in fresh drinks. This study aims to determine the effect of variations in the concentration of acids (citric acid-tartaric acid) and base (sodium bicarbonate) on the physical properties of the formula. The water pumpkin effervescent granules made with various ratios of citric acid, tartaric acid, and sodium bicarbonate consisting of FI (2: 1: 2.5); F II (1: 2: 2,5); F III (2: 1: 3,52); F IV (1: 2: 3,44). The granule made by the wet granulation method. The physical properties of the formula included organoleptic, moisture content, flow properties, compressibility index, pH, solubility time, and acceptability test. Based on the results of the evaluation of physical properties, the granule formula of the water pumpkin effervescent meets the standard requirements with a moisture content of 1.26% -2.26%, flow properties from 6.33 to 7.0 seconds, angle of repose 31.14Ëš-33.69 Ëš, compressibility index 13.61% -17.08%, pH 6.1-7.1 and dissolving time 191-223.33 seconds. Variations of citric acid-tartaric acid and sodium bicarbonate affect the physical properties and taste of the effervescent granules. Based on the acceptability test showed that the panelists liked the water pumpkin effervescent granules in FII.
PENGARUH PEMBERIAN PELAYANAN INFORMASI OBAT DAN KONSELING TERHADAP TINGKAT KEPATUHAN MINUM OBAT PADA PASIEN DIABETES MELITUS DENGAN HIPERTENSI DI RUMAH SAKIT DAERAH IDAMAN BANJARBARU Satrio Wibowo Rahmatullah; Ika Maulida Nurrahma; Adnan Syahrizal
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.519 KB) | DOI: 10.36387/jiis.v5i2.462

Abstract

Compliance to achieve treatment success can be improved by providing drug information services (PIO) and counseling to improve understanding of treatment instructions. The general objective of this study was to determine the effect of drug information service and counseling on the level of medication adherence in patients with diabetes mellitus (DM) with hypertension in the Banjarbaru Regional Hospital. This study uses a quasi experimental method with a cross sectional approach and takes patient data prospectively. The results of this study indicate that the group given PIO and counseling showed a high level of adherence as many as 20 respondents (100%). Whereas in the group that was not given PIO and the counseling level of adherence was low, there were 4 respondents (20%). Based on the mann-whitney analysis p-value = 0,000 (<α = 0.05) so that there are differences in the group with PIO and counseling with groups without PIO and counseling, while the chi square analysis p-value = 0.004 (<α = 0 , 05) so that PIO and counseling have a significant effect on the level of adherence to taking medication in patients with DM with hypertension at the Banjarbaru Regional Hospital.
TINGKAT PENGETAHUAN PASIEN TENTANG EFEK SAMPING OBAT CAPTOPRIL DAN AMLODIPIN DI PUSKESMAS SUNGAI JINGAH Novia Ariani; Dwi Rizki Febrianti; Rakhmadhan Niah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.254 KB) | DOI: 10.36387/jiis.v5i2.464

Abstract

Hypertension is an increase in systolic and diastolic blood pressure of more than 140 mmHg and90 mmHg. Captopril and Amlodipin are the most commonly used antihypertensive drugs, especially in Sungai Jingah Health Center. Long-term use is most likely to cause side effects. The level of knowledge of patients about side effects is very influential in knowing the early signs of the emergence of side effects and can prevent complications caused by side effects. The purpose of this study was to determine the level of patient knowledge about the side effects of captopril and amlodipine drugs at Sungai Jingah Health Center. This research is a non-experimental observational study. The population used was all hypertensive patients who received captopril and amlodipine drugs at the Sungai Jingah Health Center in April-May 2019. Samples were taken with consecutive sampling techniques that met the inclusion criteria of 55 patients. The research instrument used a questionnaire sheet that had been tested for validity and reliability consisting of 4 statements about the side effects of captopril and 5 items about the side effects of amlodipine. The data obtained is recapitulated and calculated using the percentage formula for each statement then presented descriptively. The results of the research on the level of knowledge about the side effects of captopril and amlodipine showed that out of 55 respondents 80.00% had a low level of knowledge, 3.64% had sufficient knowledge and 16.36% had good knowledge. The conclusion of this study is that the level of knowledge of patient knowledge about the side effects of captopril and amlodipine is in the low category (80.00%).
UJI AKTIVITAS ANTIOKSIDAN FRAKSI N-HEKSAN DAUN AFRIKA (Vernonia amygdalina Del.) DENGAN METODE DPPH Nurul Fatimah; Reksi Sundu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.876 KB) | DOI: 10.36387/jiis.v5i2.466

Abstract

Free radicals and reactive species are widely believed to contribute to the development of several diseases by causing oxidative stress and eventually oxidative. Vernonia amygdalina (Astereacea) is a small shrub or tree between 1 and 5m high growing throughout tropical Africa. Plants are generally known as bitter leaves is well cultivated and is a general market for merchandise in several countries. The purpose of this study was to determine the antioxidant activity of hexane fraction from ethanol extract od Frican leaves (Vernonia amygdalina Del.). The method used in this study was the DPPH (1,1-Diphenil-2-Picrylhydrazyl) method. The result of phytochemical screening showed that ethanolic extract of African leaves contained a composition of secondary metabolites of alkaloids, flavonoids, tannins, steroids/triterpenoids and saponins. The antioxidant activity of the extract of n-hexane fraction was classified as very weak with an IC50 value of 317.98 ppm.
POTENSI HIPOGLIKEMIA DAN HIPERGLIKEMIA PADA PASIEN DIABETES MELITUS TIPE 2 AKIBAT INTERAKSI OBAT Yardi Saibi; Delina Hasan; Bukhoriah Safitri; Vidia Arlaini Anwar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.854 KB) | DOI: 10.36387/jiis.v5i2.468

Abstract

The potency of drug interaction is higher because of the presence of comorbidities and polypharmacy in type 2 diabetes mellitus patient. This study aimed to know the potency of drug interaction event in type 2 diabetes mellitus patient in one of hospital in Jakarta in 2016 which have potency to cause hypoglycemia and hyperglicemia. Data was collected from medical record of type 2 diabetes mellitus patient . The design of this research was cross- sectional. Data retrieval was conducted retrospectively. The sample size in this study was 151 Diabetes mellitus type 2 patients medical record who received antidiabetes and met the inclusion and exclusion criteria. Data analysis was done statistically using univariate analysis . Results showed that female dominated the patient as much as 74,83% with hypertension as the most common comorbidities as much as 28,48%. There were 186 drug interaction event potency with 83,8% of them could cause hypoglicemia while the rest could cause hyperglicemia. Drug interaction with the potency that can cause either hypoglycemia and hyperglycemia that can effect the failure to get the therapeutic goal still be frequent found in patient prescription. Drug interaction event should get appropriate attention from clinical pharmacist in hospital
EVALUASI RASIONALITAS PENGGUNAAN DAN PEMBERIAN OBAT PADA PASIEN HIPERTENSI GERIATRI DI PUSKESMAS TAJINAN PERIODE JANUARI – DESEMBER 2019 Luluk Anisyah; Wibowo Wibowo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.872 KB) | DOI: 10.36387/jiis.v5i2.485

Abstract

Increasing the number of elderly causes an increase in health problems one of which is associated with hypertension which can cause complications and death. The purpose of this study was to determine the description and accuracy of the use of antihypertensive drugs in geriatric patients who were diagnosed with hypertension at the Tajinan Primary Health in Malang in the period January-December 2019. This study was an observational or non-experimental study conducted using retrospective medical record data. The measuring instrument used was the data collection sheet from the medical record, the Consensus for Hypertension Management 2019 to see the accuracy of indications, patient accuracy, drug accuracy, and dose accuracy. Data analysis using Correlation Test. The results of the correlation analysis showed that the resulting Standardize estimates were 0.002 (p <0.05) which showed that there was a significant relationship between sexes with the occurrence of hypertension. The results of the correlation analysis showed that the resulting Standardize estimates were 0.001 (p <0.05) which means that there was a significant relationship between the accuracy of the types of antihypertensive drugs used in hypertensive patients. The conclusion is that the rationality evaluation of the use and administration of drugs in hypertensive patients at the Tajinan Primary Health in Malang based on the 2019 Hypertension Management Consensus guidelines shows the accuracy both in terms of indication, drug, patient and dose.
TINGKAT PENGETAHUAN APOTEKER KOMUNITAS MENGENAI PENGOBATAN ASMA Amelia Lorensia; Rifaatul Laila Mahmudah; Leonardo Immanuel
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.369 KB) | DOI: 10.36387/jiis.v5i2.495

Abstract

Optimal asthma therapy requires collaboration between patients and pharmacists as health workers. Through pharmacy services, pharmacists have the role of providing education and monitoring asthma therapy. But the level of pharmacist's knowledge will be important in its implementation. This study studies the level of medical knowledge from the community in the city of East Surabaya. The research design used in this study was cross sectional and data collection was carried out through questionnaires from previous studies. The level of knowledge includes 6 domains, namely the domain of pharmacological therapy, etiology and pathophysiology, risk factors, resolution, symptoms, and non-pharmacological therapy. The subject is a pharmacist who practices at a pharmacy in East Surabaya. Data is collected by visiting pharmacies one by one to invite pharmacists from each pharmacy. Interviews were conducted directly with research subjects. In this study descriptive data analysis was performed. The study was conducted from April to June 2019 with 108 people. The results of the study concluded: Most subjects had moderate / standard asthma knowledge (37.96%) and only a small proportion had a high level of knowledge (27.77%). From the questionnaire questions, the lowest domain was in non-pharmacological therapy (94.00) and the lowest value was in the question domain (43.00). Therefore, pharmacists need to increase their knowledge in order to help asthma patients achieve optimal treatment. Keywords: asthma, pharmacist, pharmacy, knowledge
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN BAWANG DAYAK (Eleutherine Palmifolia L. Merr) TERHADAP KADAR GULA DARAH MENCIT PUTIH (Mus muscullus) YANG DIINDUKSI GLUKOSA Eka Kumalasari; Syifa Maharani; Aditya Maulana Perdana Putra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.983 KB) | DOI: 10.36387/jiis.v5i2.498

Abstract

Diabetes Mellitus (DM) is a collection of metabolic symptoms that arise in a person caused by an increase in blood glucose due to damage to insulin secretion or resistance to insulin or both. Diabetes mellitus medication can be either parenteral or oral which can cause side effects in long-term use such as mild diarrhea, bloating, fatigue acidosis, even hypoglycemic renal impairment. To prevent it can use alternative medicine using Dayak onion (Eleutherine palmifolia (L) Merr.). One of the active substances contained in the Dayak onion is the flavonoids. Flavonoids have antidiabetic activity through their functions as antioxidants. The study aims to determine the activity of Dayak scallion Extract (Eleutherine palmifolia (L) Merr.) To decrease blood sugar levels (Mus muscullus), which is glucose-induced. The research was conducted with research draft pre and post test with control group design. The mice used amounted to 25 male white mice that were divided into 5 groups i.e. negative control (CMC Na 0.5%), control positive (Glibenklamid 3 mg/kgBB), Dayak onion-leaf ethanol extract at a dose of 50 mg/kgBB, 100 mg/kgBB and 200 mg/kgBB. Observations of the decrease in blood sugar levels of each test group were conducted on the same day, 30 minutes, 60 and 90 after hyperglycemia. Results showed that Dayak onion leaves ethanol extract had activity as a lowering of blood sugar levels in glucose-induced white mice

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