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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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PENINGKATAN PRODUKTIVITAS LIMBAH PERTANIAN DAUN BAWANG DAYAK (Eleutherine Palmifolia L. Merr ) SEBAGAI ALTERNATIF KRIM ANTI AGING ALAMI Eka Kumalasari; Erna Prihandiwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.819 KB) | DOI: 10.36387/jiis.v4i2.363

Abstract

Eleutherine palmifolia L. Merr are typical plants of Borneo. Pharmacologically the part tubers are proven to have a therapeutic effect. Eleutherine palmifolia grow in the tropics, one of which is in the Petuk Katimpun area of ​​Palangkaraya, Central Borneo, where there land are vast Eleutherine palmifolia. After harvesting Eleutherine palmifolia will produce agricultural waste in the form of leaves that are not utilized and left to rot. Eleutherine palmifolia leaves waste extract contains flavonoid compounds and has antioxidant potential. Eleutherine palmifolia leaves antioxidants can be used to inhibit the aging of the skin and as an alternative to synthetic antioxidants which are harmful to health. Until now there has been no research that to take advantage of Eleutherine palmifolia leaves waste into active substances in antiaging creams. Therefore it is necessary to conduct research to obtain cream preparations with waste active ingredients as antiaging. Waste extract has a very strong antioxidant activity with an IC50 value of 45.33 ppm. One way ANOVA analysis that all cream had significantly different antioxidant attenuation (p < 0,05). Post Hoc analysis Formula III is a the formula with the damping antioxidant reduction the very biggest that is 63.84% ± 0.0891. From the results of the study, the waste of Eleutherine palmifolia leaves can be used as an alternative to anti-aging creams, which one of the efforts increased productivity of agricultural waste.
PENGARUH PEMBERIAN KONSELING MENGGUNAKAN BOOKLET TERHADAP PENGETAHUAN DIABETES MELLITUS MASYARAKAT DI KECAMATAN ANGGANA, KALIMANTAN TIMUR Deasy Nur Chairin Hanifa; Ika Ayu Mentari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.802 KB) | DOI: 10.36387/jiis.v5i1.367

Abstract

Diabetes mellitus is a metabolic disease characterized by an increase in blood sugar levels due to interference with insulin secretion, insulin action or both. The aim of this research is to look the effect of counseling on public knowledge about diabetes mellitus. This research was conducted in Sidomulyo Village, Anggana District. The target of the feasibility of this research is the people who are in rural areas who mostly do not know the information about the risk, prevention, and treatment of diabetes mellitus. The method was used a counseling with booklet and the discussions. The level of knowledge was assessed using the DKQ - 24. This research used a quasi-experimental method with one group pretest-posttest design. Measurement of knowledge used Wilcoxon statistical analysis. Research respondents were dominated by 68% women and 32% of men with an age range of fewer than 60 years by 77% and more than 60 years by 23%. The results of the pretest using the DKQ-24 questionnaire showed respondents with a low knowledge category of 27%, moderate knowledge of 65%, and high knowledge of 8%. Two weeks later a post-test was conducted using the DKQ-24 questionnaire, the results obtained by respondents with the category of low knowledge by 3%, moderate knowledge by 77%, and high knowledge by 20%. The average value about the prevention and treatment of diabetes mellitus, showed pretest 10.17 ± 4.891 and posttest 14.20 ± 3.119. The relationship between pre and post counseling was found with a value of p <0,000. These results indicate the effect of increasing knowledge about diabetes mellitus after counseling.
EVALUASI YIELD PRODUK TERHADAP FIX COST DAN VARIABLE COST PADA CAIRAN INFUS RINGER LACTATE Adi Suroso; Amelia Lorensia; Abdul Rahem
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.607 KB) | DOI: 10.36387/jiis.v4i2.369

Abstract

The need for quality drugs can affect the price of drugs, because there were many requirement in the manufacturing process as stated in the GMP standard. On the other hand, the price of the COGS (before production) standard and COGS varian (after production) can be different due to changes in the values of factory over head (fixed cost and variable cost). So that it requires an analysis of COGS standard and variant. This study aims to analyze the differences in the COGS variant of Ringer Lactate infusion products to COGS standard. COGS variant value was calculated based on the yield of 30 batches. Descriptive analysis was performed for (1) Value (%) of COGS standard (2) Differences in value of variable cost and fixed cost of COGS variant to COGS standard, (3) COGS standard and variant. The results showed (1) COGS standard consist of raw materials (6.70%), packaging materials (49.58%), factory over head with variable costs (25.80%) and Fixed costs (18.00%); (2) The average yield of 30 batches was 94.947% and this causes in differences in variable cost of COGS variant - standard 4.422% and the differences in fixed cost of COGS variant – COGS standard 3,958% (3) There was 4,201 % differences in COGS variant to standard. Product yield influences the value of variable cost and fixed cost of COGS variants, causing a gap to the COGS standard. So that this gap should considered in setting the COGS standard.
MINYAK ATSIRI JERUK KALAMANSI (Citrus microcarpa) SEBAGAI FORMULASI MASKER GEL (Peel-Off Mask) Yuska Noviyanty; Hepiyansori Hepiyansori; Fransisca Epri Esaliya
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.007 KB) | DOI: 10.36387/jiis.v5i1.374

Abstract

The use of Citrus microcarpa essential oil is not widely known by the public. contains antioxidant compounds such as limonen and vitamin C. The dosage formulation is made in the form of Gel Mask (Peel-Off Mask) because Gel Mask (Peel-Off Mask) is a mask that is practical in its use, after drying the mask can be removed immediately and is able to remove the remnants of dirt that sticks to the surface of the facial skin. The process of making Gel Masks (Peel-Off Mask) of Kalamansi Orange Essential Oil (Citrus microcarpa) uses a variation of the concentration of Kalamansi Orange Essential Oil (Citrus microcarpa) 2%, 4%, 6%, the base used as Gelling Agent is PVA and HPMC, and evaluation of dosage includes organoleptic test, homogeneity test, dispersion test, dry time test, pH test, preference test or hedonic test. The results showed that Kalamansi Orange Essential Oil (Citrus microcarpa) can be made with a gel mask (Peel-Off Mask) and the difference in concentration can affect the physical properties of the Peel-Off Mask which includes the consistency and odor of the Gel Mask (Peel-Off Mask). Of the four formulas (F0, F1, F2, F3) the best preparation is F3 with a concentration of Kalamansi Orange Essential Oil (Citrus microcarpa) 6%.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN JERUK PURUT (Citrus hystrix (D.C)) TERHADAP BAKTERI Propionibacterium acnes Fitriyanti Fitriyanti; Muhammad Hafizudin; Muhammad Nazarudin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.201 KB) | DOI: 10.36387/jiis.v5i1.376

Abstract

Lime leaves contain flavonoids, tannins, saponins and steroids which are thought to have antibacterial activity. This study aimed to determine the antibacterial activity of the methanol extract of Lime leaves to P.acnes bacteria and to determine the activity of methanol extract of the leaves of Lime based on the value of the diameter of the inhibitory zone and the inhibition category. Lime Leaves extracted by the maceration method using methanol solvent followed screening tests phytochemical. The antibacterial activity test was carried out by the sump method with 6 concentrations of methanol extract of the leaves of Lime according to 25mg/mL, 50mg/mL, 100mg/mL, 200mg/ mL, 300mg/mL and 400mg/mL, positive control of clindamycin 0,1% and negative control Na-CMC 0,5%. The results of phytochemical screening, methanol extract positively contain flavonoids, saponins, tannins, and steroids. Antibacterial test results showed that the inhibition zone of the Lime leaves of the methanol extract in the concentration of 25 mg/ml, and 50 mg/mL was 8.35 and 9.4 mm (medium category), concentrations of 100 mg/ml, and 200 mg/mL were 11.77, and 19.45 mm (strong category), and concentrations of 300mg / ml, and 400mg/mL, namely 21.05, and 22.87 mm (very strong categories). SPSS test results there were significant differences between treatment groups (sig <0.05).
AKTIVITAS IMUNOMODULATOR EKSTRAK ETANOL SPONS Callyspongia sp. TERHADAP FAGOSITOSIS MAKROFAG PADA MENCIT JANTAN BALB/C. Muhammad Ilyas Y.; Asriullah Jabbar; Mentarri Bafadal; Muhammad Hajrul Malaka; Firdayanti Firdayanti; I. Sahidin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.441 KB) | DOI: 10.36387/jiis.v5i1.377

Abstract

Sponge Callyspongia sp. has compounds that act as immunomodulatory agents, one of which is flavonoids.Flavonoids have the potential to be immunostimulants by increasing the phagocytic activity of macrophages. This study was experimental with a post test only control group design method. This study used 24 micemalestrain Balb /c with a body weight of 20-30 grams divided into 6 groups. The first group get extracts of sponge Callyspongia sp. 100 mg/kgBW, second group get the extract of sponge Callyspongia sp. 200 mg/kgBW, third group get extracts of sponge Callyspongia sp. 300 mg/kgBW, fourth group get the extract of sponge Callyspongia sp. 400 mg/kgBW, positive control group was given Stimuno® 0,13 mg/kgBW and the negative control group get Na-CMC 0.5%. A test given in orally preparations on the first day until the seven day. On the eighth day of each of the mice are injected bacteria Staphylococcus aureus (SA) by intraperitoneal. The activity of macrophage cells from murine peritoneal fluids sweep by calculating the percentage of macrophages that does phagocytosis of 100 cells are observed. The data obtained were then analyzed by one way Anova statistics and test post hoc Tukey's. As result, the are that ethanol extracts of sponge Callyspongia sp. at doses of 300 mg/kgBW and 400 mg/kgBW have potential as immunomodulator with based on results of statistical tests post hoc Tukey (P > 0.05) showed no meaningful difference against the positive control (Stimuno ®) wich improving the activity of the cells of the macrophage phagocytosis.
ANALISIS MUTU PELAYANAN PETUGAS FARMASI DAN KETERSEDIAAN OBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI RS SANTA CLARA MADIUN TAHUN 2019 Diah Nurcahyani; Vidya Kartikaningrum
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.135 KB) | DOI: 10.36387/jiis.v5i1.384

Abstract

Service quality, pharmaceutical providers, and the availability of medicines determine the outpatients’ satisfaction in the Department of Hospital Pharmaceutical Installation (IFRS). The phenomena, found in RS Santa Clara Madiun, are that and patients usually wait too long to get medicines, and the presence of empty drugs. The objective of the research was to find out the influence of the service quality pharmaceutical providers and the availability of medicines on the outpatients’ satisfaction in RS Santa Clara, in June 2019. The research was an cross sectional method on 100 outpatients, using accidental sampling technique. The data were gathered by using questionnaires and analyzed by using bilinear regression test (α= 0,05). The result of the research showed that the variables of pharmaceutical providers and the availability of medicines influenced patients’ satisfaction (p < 0.005). The variable of the availability of medicines had the most dominant influence on outpatients’ satisfaction at the coefficient value of (β) 0.853).
EFEK ADAPTOGENIK EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana L.) PADA MENCIT (Mus musculus) MENGGUNAKAN METODE SWIMMING ENDURANCE TEST Abdul Wahid Jamaluddin; A. Magfira Satya Apada
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.796 KB) | DOI: 10.36387/jiis.v5i1.385

Abstract

Adaptogenic activity was related to antioxidant activity which can reduce the number of free radicals, which in turn will reduce stress and improve body balance. Mangosteen rind (Garcinia mangostana L.) with a large antioxidant content promises to be Adaptogen. This study aims to examine the Adaptogenic effects of Ethanol Extract of mangosteen peel (Garcinia Mangostana L.) Using the Swimming Endurance Test (SET) in Mice. Simplicia of Mangosteen Fruit extracted by maceration using 96% ethanol, then tested its Adaptogen activity based on swimming endurance test. The group consisted of negative control (NaCMC 1%), positive control (Vit C. 100 mg / kg BB) and 3 groups treatment of ethanol extract of mangosteen peel ranging from 100, 200 and 400 mg / kg BB where all groups were given oral 1x1 oral administration for 7 days and on the 8th day, a SET test were performed. After that, data analysis was performed statistically. The results showed that the ethanol extract of mangosteen peel had the ability to be Adaptogenic where mice swimming in all groups given mangosteen peel extract was longer than the negative group with a significant difference (p <0.05). Ethanol extract of mangosteen peel showed a strong adaptogenic antistress effect in mice based on increased swimming time ability of mice.
PENGARUH PENGETAHUAN-SIKAP MENGENAI VITAMIN D TERKAIT OBESITAS PADA MAHASISWA Amelia Lorensia; Dian Natasya Raharjo; Novelia Gandawari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.286 KB) | DOI: 10.36387/jiis.v5i1.388

Abstract

Indonesia as a tropical country has a tendency to experience vitamin D deficiency. Knowledge and attitudes towards sun exposure contribute to the risk of vitamin D deficiency. In the midst of urban life patterns, obesity also increases the risk of vitamin D deficiency. This study was conducted to determine the effect of the level of knowledge and attitudes regarding vitamin D related to obesity in adults, which was conducted in March 2018 to January 2019. The study used a cross sectional design, with a knowledge and attitude questionnaire regarding vitamin D. Respondents were adults and domiciled in Surabaya , as many as 74 people in each group of obesity and non-obese. The results showed that obese and non-obese respondents both had good knowledge (OR 1.138) but had a bad attitude (OR 1,000). There was no significant difference in knowledge and attitudes in the two groups, and had a weak correlation.
STUDI PENGEMBANGAN INSTRUMEN EDUKASI UNTUK MENURUNKAN RISIKO PCOS (Polycystic Ovary Syndrome) PADA WANITA DENGAN OBESITAS Ratna Widyasari; Adhisty Kharisma Justicia; Pinda Hutajulu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.593 KB) | DOI: 10.36387/jiis.v5i1.391

Abstract

Women with obesity would experience an increase in lipid. These lipids would be accumulated in the visceral part of the body caused anovulation that is part of the menstrual disorder called polycystic ovary syndrome (PCOS). This study aims to know factors that could affect obese women to change their lifestyle and to develop an instrument to educate obese women to decrease the risk of PCOS. This study consisted of three steps. In the first step, the obese woman was evaluated qualitatively using semi-structured interviews to know their education needs. In the second step, the education instrument was developed based on their education need. In the third step, the instrument education that had been developed was evaluated. The result showed that the kind of factors affecting obese women to change lifestyle was patient inside-factors and patient outside-factor (environment). Most of the patients had low knowledge about the disease and the cure causing misperception and uncompliance. Therefore, the education instrument was developed using the booklet. The result of the evaluation instrument showed that the booklet that had been developed could increase patient knowledge o change patient uncompliance behavior.

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