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Jurnal Ilmu Kesehatan Indonesia (JIKSI)

jikesi
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Published by Universitas Andalas

ISSN : - EISSN : 27224848 DOI : https://doi.org/10.25077/jikesi.v1i3

Core Subject : Health, Science,

Immunology & microbiology Medicine & Pharmacology Public Health

Jurnal Ilmu Kesehatan Indonesia is a peer-reviewed and open-access journal that focuses on promoting health sciences to integrate research in all aspects of human health. This journal publishes original articles, reviews, and case reports. Subjects suitable for publication include but are not limited to the following fields: Anesthesiology Cardiovascular Cell and molecular biology Child health Dermato-venereology Histopathology Internal medicine Neuro-psychiatric medicine Nutrition Obstetrics and Gynecology Ophthalmology Otorhinolaryngology Pharmacology Pulmonology Radiology Surgery

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 328 Documents

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Perbedaan Kadar Non High Density Lipoprotein Cholesterol pada Mahasiswa Penyandang Obes dan Non Obes Sri Vanny Suhirman; Efrida Efrida; Rismawati Yaswir
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

ABSTRACT THE DIFFERENCE OF NON HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN OBESE AND NON OBESE STUDENT By Sri Vanny Suhirman Non High Density Lipoprotein Cholesterol was calculated as total cholesterol levels minus HDL levels. Non HDL-C levels can be used as a predictor of cardiovascular disease risk. Non HDL-C levels tend to increase in obese people. This research aims to determine the differences of non HDL-C levels in obese and non obese students. This research was an observational analytic study with a cross sectional design. This research was conducted at the Central Laboratory of Dr. M. Djamil Hospital Padang from July 2020 to February 2021. The sample was 60 students at Faculty of Medicine, Andalas University, consists of 30 obese students and 30 non obese students. Statistical analysis used the independent T-test. The significant test results if the p value <0.05. The results showed that the mean age of the subjects was 20.32±1.05 years. The mean BMI in obese student was 32.53 ± 4.13 kg/m2 and the mean BMI in non obese student was 21.11 ± 1.85 kg/m2. The mean non HDL-C level in the obese student was 131.43 ± 34.70 mg/dL and the mean non HDL-C level in non obese student was 123.93 ± 35.55 mg/dL. Bivariate analysis found that there was no significant difference between the mean non-HDL C levels in the obese student and non obese student (p = 0.412). The conclusion in this research is the mean non HDL-C levels in the obese and non obese student is not different. Keywords: Body mass index, Non High Density Lipoprotein Cholesterol, Obesity

Penggunaan Kortikosteroid pada Pasien Anak dengan Perikarditis Tuberkulosis. Novi Violona Edwar; Abi Andayu; Finny Fitry Yani
Jurnal Ilmu Kesehatan Indonesia Vol 1 No 3 (2020): November 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Tuberculous pericarditis (TB pericarditis) is a disease that still frequently occurs in developing countries. The mortality rate due to TB pericarditis is still quite high, reaching 17-40%. Death due to tuberculous pericarditis is influenced by adequate or not treatment. The use of additional corticosteroid therapy is still a matter of debate in the treatment of tuberculous pericarditis. Writing this case aims to see the outcome of the use of corticosteroids in patients with tuberculous pericarditis. Literature searches were carried out through Pubmed and Google Scholar. From the results of literature search, two meta-analyzes were obtained that discussed the use of corticosteroids in tuberculous pericarditis. In children with tuberculous pericarditis, the use of corticosteroids does not reduce mortality, but can reduce complications due to tuberculous pericarditis. Keywords: corticosteroids, tuberculous pericarditis, outcome.

Hubungan Aktivitas Luar Ruangan dengan Miopia Mahasiswa Kedokteran Angkatan 2019 Universitas Andalas Nabila Alifina; Kemala Sayuti; Ulya Uti Fasrini
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: Myopia or nearsightedness is a condition in which light entering the eye is focused in front of the retina, resulting in the blurry appearance of distant objects. This can be caused by disturbances in the regulation of eye growth that can be hereditary or coming from the environment, for example from outdoor activities. Based on research in 2017 in Beijing stated that more frequent outdoor activities can reduce the risk of myopia.Objective: The purpose of this study was to analyze the relationship between outdoor activity and myopia in medical students of Andalas University batch 2019.Methods: This is an analytic study with a case-control design through consecutive sampling techniques. The sample consisted of 60 respondents, 30 of them which suffered myopia and another 30 with ametropia. Data was collected using a questionnaire that has been tested for validity. Outdoor activities, namely all activities carried out in the wild or outdoors and exposed to sunlight for approximately three hours per day. The processing of the data was done with a statistical chi-square test.Results: 45% of the respondents with outdoor activity less than three hours have myopia and 5% of respondents with outdoor activity more than three hours have myopia. Statistical chi-square test was performed to see the relationship between outdoor activity and myopia with p-value = 0.001 (p <0.05).Conclusion: It was concluded that there was a significant relationship between outdoor activity and myopia in medical students of Andalas University batch 2019.

Perkembangan Pengobatan Topikal Untuk Dermatitis Seboroik Wajah Azaria Ramadhani Zulkifli; Rina Gustia; Taufik Ashal
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background: Seborrheic dermatitis is a chronic and recurring skin disorder with clinical manifestations as erythematous macules or plaques with a scale associated with pruritus. The most common predilection is the face area. Treatments for seborrheic dermatitis should address the normalization process of skin function and structure, not only relieving the symptoms and clinical symptoms of the disease. Thus, leading to long-term remission. Objective: The narrative review was conducted by reviewing the articles that discussed about the treatment effectiveness on facial seborrheic dermatitis. Methods: Articles search was carried out through databases such as Pubmed and Google Scholar with determined keywords and selected based on inclusion and exclusion criteria. Results: In total, six articles were reviewed with 184 cases of facial dermatitis seborrheic. All studies showed significant improvement. This review included additional literatures to support the results of the main literatures. Conclusion: The treatments commonly used for seborrheic dermatitis these days are pharmacological treatments in the form of topical and systemic drugs as well as non-pharmacological treatments. Topical drugs were able to repair the clinical manifestation on mild to moderate seborrheic dermatitis whereas systemic drugs were indicated for cases with wide lesions and more severe condition. Non-pharmacological treatment can be used as an adjuvant to accelerate the clinical condition.

Hubungan Stone Burden dengan Penurunan Hemoglobin Pasca Operasi Percutaneous Nephrolithotomy di RSUP DR. M. Djamil Padang Millenia Calista; Yevri Zulfiqar; Rina Gustia
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Kidney stones are one of the three most common cases in urology. The best standard management for kidney stones with stone burden >20mm is PCNL (percutaneous nephrolithotomy), a minimal invasive method that uses percutaneous access to remove stones. One of the most complications was bleeding which can be caused by several factors , one of them is stone burden.Objective. to look at the relationship of stone burden with hemoglobin drop after PCNL in patients with renal stoneMethods. This study is an analytical study with retrospective approach towards all patients diagnosed with kidney stones and treated with PCNL at RSUP Dr. M. Djamil Padang at based on patient medical record data. Data analysis used Chi square tests where the relationship between variables is said to be significant if p value <0.05Results. Data showed that from 65 kidney stone patients treated with PCNL, the highest prevalence were men and the most age group are 45-64 years. The most types of stones are staghorn and the highest stone burden is 20 - ≤30 mm. Some cases with the involvement of hydronephrosis with an average length of stay <5 days. Hemoglobin drop mean in kidney stones ≤2gr / dL. Statistical analysis showed that there is no relationship between stone burden and hemoglobin drop after PCNL in kidney stone patients (p value = 0,706).Conclusion. The conclusion of this studied is that there is no significant relationship between stone burden with hemoglobin drop after PCNL in patients with kidney stone.

Small cell neuroendocrine carcinoma of the uterine cervix (SCNEC): a case report and review Puja Agung Antonius; Hariyono Winarto
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Objective: Improving skill and knowledge to diagnose and manage a rare case of small cell neuroendocrine uterine cervical cancer Method: a Case report Result: A 51 years old, para 2, Indonesian woman with chief complaint post-coital vaginal bleeding. Gynecology examination revealed cervical exophytic fragile mass size 3x3x3,5 cm, easily bleeding, with a necrotic part, infiltrated both parametria but not reach the pelvic wall correspond to stage IIB. Initially, the histopathology result from punch biopsy was an adenocarcinoma well-differentiated, with no lymph vascular invasion, DD/ adenosquamous, neuroendocrine tumor. We did the histopathology review continued with immunohistochemistry examination. Immunohistochemistry result showed that although all the sample was not typical, immunohistochemical outward patterns can support morphological features of high-grade neuroendocrine carcinoma, small cell type. We proceed here for chemoradiation therapy. Conclusion: Small cell neuroendocrine carcinoma of the uterine cervix is a rare case. Histopathology and immunohistochemistry examination has an important role to develop the diagnosis. Although the prognosis is poor, adjuvant chemotherapy or chemoradiation was associated with improved survival in patients with advance staged. Keywords: SCNEC, immunohistochemistry, chemoradiation

Invasive epithelial ovarian carcinoma (EOC) at a young age: role of fertility-sparing Puja Agung Antonius; Tricia Dewi Anggraeni
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Objective: Improving knowledge to manage an invasive epithelial ovarian cancer at a young age who expect to preserve their reproductive function Method: a Case report Result : A 26 years old, nulliparity, Indonesian woman with chief complaint abdominal enlargement simultaneous with dyspnoea condition. Physical examination revealed an enlarged abdomen until processus xhypoideus with positive shifting dullness. Gynecology examination found normal uterine size, palpable cystic mass originated from adnexa until navel, mobile. CT whole abdomen showed a cystic solid mass in the pelvic area up to mid abdominal size 17,8 x 10,7 x 18,8 cm accompanied by lymphadenopathy in paraaortic and bilateral inguinal. Ascites and pleural fluid cytology examination results were both positive for malignant cells (metastatic adenocarcinoma). The patient was assessed as advanced staged ovarian cancer and procced for Interval Debulking Surgery (IDS) after 3 cycles of Neoadjuvant Chemotherapy (NACT). Postoperative histopathology examination result was high-grade clear cell ovarian carcinoma Conclusion: Fertility-sparing surgery for invasive epithelial ovarian carcinoma could be chosen for selective young age patients who fulfilled the criteria. Education and informed consent is a must regarding the risk of recurrence and prognosis. Keywords: Invasive EOC, fertility sparing, selection criteria, recurrence, prognosis

Profil Pasien Deep Vein Thrombosis di RSUP Dr. M. Djamil Padang Tahun 2018 Muhammad Farhan; Masrul Syafri; Tofrizal Tofrizal
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Latar Belakang. Deep Vein Thrombosis (DVT) merupakan sebuah kondisi oklusi yang disebabkan oleh terbentuknya trombus patologis pada sirkulasi vena dalam tubuh. DVT merupakan sebuah penyakit yang dapat dicegah namun masih memiliki tingkat morbiditas dan mortalitas yang tinggi. Pemeriksaan menggunakan Ultrasonografi (USG) Doppler merupakan metode yang direkomendasikan untuk menegakkan diagnosis DVT. Objektif. Tujuan penelitian ini adalah untuk mengetahui profil dari pasien DVT di RSUP Dr. M. Djamil Padang pada tahun 2018. Metode. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross sectional melalui pengumpulan data dari hasil pemeriksaan USG Doppler dan rekam medis. Background. Deep Vein Thrombosis (DVT) is an occlusion caused by patological thrombus that formed at deep vein circulation of the body. DVT is a preventable disease but the morbidity and mortality rate of DVT are still high. The recommended method for diagnosing DVT is by examination with Doppler Ultrasonography (USG) for identificating thrombus at deep vein circulation. Objective. The objective from this study is to identifying clinical profile of DVT patient at Dr. M. Djamil General Hospital Padang in 2018. Method. This is a descriptive observational research with cross sectional method by collecting data from Doppler USG examination report and patient medical record. Results. From this research we found 66 DVT patient, most patients were in the age group of 56-65 years old (23 patients), most thrombus located at lower extremities (49 patients), especially at femoral vein (29 patients). Mostly patients shown with swelling at thrombus location (59 patients), and immobilization was the most risk factor found in the patients (58 patients.) Conclusion. From this research we conclude that mostly DVT patients at M. Djamil General Hospital Padang are elderly and mainly women, mostly DVT located at left leg especially in femoral and poplitea vein and shown with swelling at leg, and mostly DVT patients were having immobilization and malignancy as risk factor. Keywords : Deep vein thrombosis, Doppler USG, clinical profile Hasil. Pada penelitian ini didapatkan 66 pasien DVT di RSUP Dr. M. Djamil Padang pada tahun 2018. Kelompok usia tertinggi ditemukan pada rentang usia 56-65 tahun sebanyak 23 pasien. Lokasi trombus paling sering ditemukan pada tungkai sebanyak 49 pasien, terutama pada vena femoralis sebanyak 29 pasien. Manifestasi klinis yang paling sering ditemukan berupa pembengkakan sebanyak 59 pasien, dan faktor risiko yang paling sering ditemukan imobilisasi sebanyak 58 pasien. Kesimpulan. Kebanyakan pasien DVT di RSUP Dr. M. Djamil Padang berusia lanjut serta memiliki DVT pada tungkai terutama pada vena femoralis sebelah kiri dengan manifestasi pembengkakan, dan memiliki faktor risiko imobilisasi. Perlunya penerapan profilaksis DVT pada pasien yang memiliki resiko tinggi untuk menekan angka kejadian DVT. Kata kunci: Deep vein thrombosis, USG Doppler, profil klinis

Profil Pasien Perforasi Gaster di RSUD Kolonel Abundjani Bangko pada Tahun 2020 Shinta Qorina
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Background. Gastric perforation is one of the serious complications caused by a peptic ulcer, with the appearance of symptoms in the form of an acute abdomen that requires immediate treatment. Approximately 2 to 3% of all ulcers perforate which usually occurs in the anterior wall of the duodenum or stomach. Objective. To determine the profile of patients with gastric perforation due to peptic ulcer at RSUD Kolonel Abundjani Bangko. Method. This is descriptive study with a retrospective total sampling method. The target population is patients with a diagnosis of gastric perforation due to peptic ulcers in the period January-December 2020. Result. Total patients with gastric perforation in RSUD Kolonel Abundjani Bangko for the January-December 2020 period totaled 14 people. Male patients were more than female (64.3% vs. 35.7%), the age range of 50-59 years was slightly higher than patients aged over 60 years (50% vs. 42.9%). There was no difference in the number of patients who had and did not have a history of taking NSAIDs. The location of the pre-pyloric perforation (50%) was more common than in the major curvature (14.29), minor (21.43%), and corpus (14.29%). The diameter of the perforation was most commonly found 0.5-1 cm (85.71%) Total deaths were 3 out of 14 people (21.43%). Conclusion. There are more male patients with gastric perforation than female, and the age range of 50-59 years is more common. The location of the perforation was found mostly in the pre-pylorus, and the majority had a perforation diameter of 0.5-1 cm. The mortality rate was reported as 21.43%

Kajian Literatur: Efektivitas Antiseptik Yang Mengandung Chlorhexidine Gluconate Terhadap Bakteri MRSA Farinda Amalya Hakiman; Netti Suharti; Elizabeth Bahar
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Latar Belakang: Chlorhexidine gluconate merupakan antiseptik yang sering digunakan untuk mencegah penyebaran infeksi karena luasnya cakupan antiseptik tersebut dalam membunuh bakteri. Antiseptik ini juga sering digunakan untuk mencegah penyebaran infeksi beberapa bakteri MDRO, salah satunya bakteri MRSA. Akan tetapi, seringnya penggunaan antiseptik tersebut dikhawatirkan dapat meningkatkan resistensi bakteri MRSA terhadap chlorhexidine gluconate. Objektif: Studi ini bertujuan untuk mengetahui efektivitas antiseptik dengan kandungan chlorhexidine gluconate terhadap bakteri strain MRSA. Metode: Kajian literatur naratif ini menggunakan artikel hasil pencarian Google Scholar dan PubMed dengan kata kunci “Methicillin Resistant Staphylococcus aureus”, “MRSA”, “Anti-Infective Agents, Local”, dan “Chlorhexidine gluconate” yang diterbitkan dalam 10 tahun terakhir (2010-2020), dan menggunakan Bahasa Inggris. Artikel yang tidak bisa didapatkan secara lengkap dan literature review dieksklusi. Artikel kemudian dinilai menggunakan critical appraisal checklist untuk dikaji. Hasil: Hasil pencarian menampilkan 355 artikel, dimana 345 artikel dieliminasi berdasarkan kriteria inklusi dan eksklusi, sehingga didapatkan 8 artikel. Delapan artikel yang ditinjau terdiri dari empat studi terkontrol acak, dua studi laboratorium, satu uji hewan, dan satu studi observasional. Kesimpulan: Penelitian ini mendapatkan 8 literatur untuk dikaji. Lima literatur melaporkan bahwa chlorhexidine gluconate menurunkan prevalensi infeksi bakteri MRSA, walaupun dua literatur menyatakan bahwa penurunan tersebut tidak signifikan. Tiga literatur lain melaporkan adanya penurunan sensitivitas bakteri MRSA terhadap chlorhexidine gluconate, terutama pada isolat yang diidentifikasi memiliki gen qacA/B atau gen smr. Background: Chlorhexidine gluconate is an antiseptic that can prevent infection because of its broad-spectrum antimicrobial activity. It can prevent MDRO infection, including MRSA. However, frequent use of chlorhexidine gluconate may result in the emergence of MRSA with reduced susceptibility or even resistance against it. Objective: This study aims to determine the effectiveness of an antiseptic containing chlorhexidine gluconate against MRSA. Methods: A literature search of PubMed and Google Scholar was performed with keywords such as “Methicillin Resistant Staphylococcus aureus”, “MRSA”, “Anti-Infective Agents, Local”, and “Chlorhexidine gluconate”. Articles published from the last 10 years in English were included. Articles that were not available in full text as well as literature reviews were excluded. These articles were appraised using critical appraisal checklist for review. Results: We identified 355 articles, of which 345 were eliminated based on the inclusion and exclusion criteria, leaving 8 articles. These eight articles consisted of four randomized controlled studies, two laboratory studies, one animal study, and one observational study. Conclusion: Five studies reported that chlorhexidine gluconate reduces rate of MRSA infection, although two studies stated that the rates are not significant. Three studies reported reduced susceptibility against chlorhexidine gluconate in MRSA isolates with qacA/B or smr genes.

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Fathiyyatul Khaira

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Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Fathiyyatul Khaira

Contact Email fathiyyatul.khaira@gmail.com

Phone +6285161910033

Journal Mail Official jikesi.editorial@gmail.com

Editorial Address Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location Kota padang, Sumatera barat INDONESIA

Abstract

Abstract

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Abstract

Abstract

Abstract

Contact Name
Fathiyyatul Khaira

Contact Email
fathiyyatul.khaira@gmail.com

Phone
+6285161910033

Journal Mail Official
jikesi.editorial@gmail.com

Editorial Address
Fakultas Kedokteran Universitas Andalas. Jln. Limau Manis, Pauh – Padang – Sumatera Barat. 25163.

Location
Kota padang,

Sumatera barat

INDONESIA