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Jurnal Neuroanestesi Indonesia

jni
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Published by Indonesian Society of Neuroanesthesia & Critical Care

ISSN : 20889674 EISSN : 24602302 DOI : https://doi.org/10.24244/jni

Core Subject : Health, Science, Education,

Biochemistry, Genetics & Molecular Biology Education Medicine & Pharmacology Neuroscience Public Health

Editor of the magazine Journal of Neuroanestesi Indonesia receives neuroscientific articles in the form of research reports, case reports, literature review, either clinically or to the biomolecular level, as well as letters to the editor. Manuscript under consideration that may be uploaded is a full text of article which has not been published in other national magazines. The manuscript which has been published in proceedings of scientific meetings is acceptable with written permission from the organizers. Our motto as written in orphanet: www.orpha.net is that medicine in progress, perhaps new knowledge, every patient is unique, perhaps the diagnostic is wrong, so that by reading JNI we will be faced with appropriate knowledge of the above motto. This journal is published every 4 months with 8-10 articles (February, June, October) by Indonesian Society of Neuroanesthesia & Critical Care (INA-SNACC). INA-SNACC is associtation of Neuroanesthesia Consultant Anesthesiology and Critical Care (SpAnKNA) and trainees who are following the NACC education. After becoming a Specialist Anesthesiology (SpAn), a SpAn will take another (two) years for NACC education and training in addition to learning from teachers in Indonesia KNA trainee receive education of teachers/ experts in the field of NACC from Singapore.

Arjuna Subject : Kedokteran - Anesthesiology and Pain Medicine

Articles 363 Documents

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Analisis Penambahan Dexmedetomidine pada Operasi Besar Tulang Belakang Elektif di RSUD Dr. Soetomo Rizkiya, Putri; Rehatta, Nancy Margarita; Harijono, Bambang; Herawati, Lilik
Jurnal Neuroanestesi Indonesia Vol 9, No 2 (2020)
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Latar Belakang dan Tujuan: Dexmedetomidine (DEX) suatu agonis ?2, telah banyak digunakan untuk mengendalikan respon stress pembedahan melalui penekanan respon simpatis dan endokrin. Studi ini bertujuan untuk menganalisis efek penambahan dexmedetomidine terhadap kadar kortisol, nadi, tekanan arteri rerata, kebutuhan penggunaan fentanyl dan isoflurane pada operasi tulang belakang.Metode: Sebuah studi randomisasi terkontrol tersamar ganda dilakukan pada pasien yang menjalani operasi besar tulang belakang elektif di RSUD Dr. Soetomo, Surabaya. Nadi, tekanan arteri rerata, kebutuhan fentanyl dan isoflurane serta perubahan kadar kortisol pre dan post-operatif dibandingkan antara pasien yang memperoleh dexmedetomidine (DEX) dan placebo (SAL).Hasil: Nadi dan tekanan arteri rerata lebih stabil pada kelompok DEX pada saat intubasi, prone positioning dan insisi. Perubahan kadar kortisol pada kelompok DEX (9,95,2 mcg/dl) lebih rendah dibanding kelompok SAL (11.78.4 mcg/dl) namun tidak berbeda bermakna secara statistik (p=0.88). Penggunaan fentanyl dan isofluran pada kelompok DEX dapat dikurangi masing-masing 50% (p=0,00) dan 30% (p=0,00). Kecepatan pulih sadar kelompok DEX lebih cepat. (p=0,001) Simpulan: Hemodinamik yang stabil, berkurangnya penggunaan opioid dan anestesi inhalasi serta proses pulih sadar yang lebih cepat pada kelompok DEX mendukung penggunaan dexmedetomidine dalam operasi besar tulang belakang.Analysis of Dexmedetomidine Addition in Elective Major Spinal Surgery in RSUD Dr. SoetomoAbstractBackground and Objective: Dexmedetomidine (DEX) an ?2 agonist, is widely used to control stress response during surgery through inhibition of sympathetic and endocrine response. This study aims to analyze the effect of dexmedetomidine addition towards blood cortisol level, pulse rate, mean arterial pressure, and fentanyl and isoflurane use during major spinal surgery.Method: A randomized doubleblind controlled study was conducted on twenty patients undergoing major spinal surgery in RSUD dr. Soetomo, Surabaya. Pulse rate, mean arterial pressure, fentanyl and isoflurane used, and plasma cortisol changes were compared between patients receiving dexmedetomidine (DEX) and placebo (SAL). Results: Pulse rate and mean arterial pressure was more stable in DEX group during intubation, prone positioning and incision. Changes in cortisol level in DEX group (9.95.2 mcg/dl) was lower, but not statistically significant fromSAL group (11.78.4 mcg/dl,p=0.88). Fentanyl and isoflurane use in DEX group was reduced 50% (p=0.00) and 30% (p=0.00) respectively. Recovery time in DEX group was faster (p=0.001).Conclusion: Hemodinamik stability, reduced opioid and inhalational anesthesia use, and faster anesthesia recovery time supports dexmedetomidine as anadjunct in general anesthesia in major spinal surgery.

Perdarahan Berulang Pascakraniotomi pada Pasien Cedera Kepala Ringan Fithrah, Bona Akhmad; Oetoro, Bambang J.; Umar, Nazaruddin; Saleh, Siti Chasnak
Jurnal Neuroanestesi Indonesia Vol 5, No 3 (2016)
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Kraniotomi adalah prosedur pembedahan yang digunakan untuk mengangkat tumor untuk memperbaiki lesi vascular atau menurunkan tekanan intrakranial. Salah satu komplikasi dari prosedur ini adalah terjadinya perdarahan hingga harus dilakukan pembedahan kembali. Cedera kepala ringan memiliki angka kejadian sekitar 8090% dari seluruh cedera kepala dan memiliki angka kematian sekitar 0,1% itu terjadi disebabkan oleh perdarahan intra cerebral yang terlewat. Seorang laki laki usia 47 tahun, berat badan 106 kg dirujuk dari rumah sakit kecil setelah terpelesat saat turun dari angkutan umum. Pasien tidak sadarkan diri dan saat tersadar sudah di instalasi gawat darurat. Hemodinamik pasien baik,GCS E4M6V5, telah dilakukan CT scan dan tidak didapatkan perdarahan apapun. Pasien dua hari di ruang rawat dan terus mengeluh sakit kepala yang bertambah. Dilakukan CT scan ulang dan didapatkan perdarahan intracerebral. Dilakukan tindakan kraniotomi evakuasi hematom dan pasca operasi pasien dirawat di ICU. Dua hari di ICU pasien kembali mengalami penurunan kesadaran dan pada CT scan didapatkan kembali perdarahan pada tempat yang sama. Dilakukan kembali kraniotomi evakuasi hematom dan pasca tindakan pasien dirawat di ICU. Dengan pengawasan yang baik dan tindakan yang cepat cedera kepala ringan yang mengalami perdarahan intracerebral dapat diatasi dengan baik dan tidak menjadi suatu kematianRecurrent Post Craniotomy Hemorrhage in Patient with Mild Head InjuryCraniotomy is a procedure performed to remove brain tumor, repair vascular lesion or relieve intracranial pressure. Sometimes complication arise that need re-do craniotomy. Incidence mild traumatic brain injury 8090%from all traumatic brain injury and has mortality 0,1% related with missed intra-cranial hemorrhage. Patient, 47 years old, body weight 106 kgs referred from smaller hospital after slipped and falling down from the bus. Patient said he had unconscious for several minutes. Patient had already had CT scan and no bleeding at all. Patient stayed in the ward for two days and keep complaining severe headache. CT scan conduct again and the result said there were intracranial hemorrhage. Craniotomy evacuation hemorrhage performed and after operation patient stayed in the ICU. Two days in the ICU patient had decreased of consciousness. CT scan immediately performed and there was another intracranial hemorrhage in the same place with bigger volume. Re-do craniotomy evacuation hemorrhage performed again. With a good monitoring in the room/ICU, a fast diagnostic and craniotomy this patient wouldnt become a mortality case

Cardiac Arrest Intra Operatif Pada Neuroanestesi Pediatrik Prihatno, MM Rudi; Manulima, Teguh
Jurnal Neuroanestesi Indonesia Vol 8, No 1 (2019)
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Henti jantung (cardiac arrest) intra operatif merupakan penyulit yang paling menakutkan selama pembedahan berlangsung, terutama pada kasus-kasus bedah saraf pediatrik, dikarenakan akan berpengaruh pada luaran operasi dan dampak jangka panjang yang ditimbulkannya. Resiko yang lebih berat adalah kematian di meja operasi. Seorang anak perempuan 10 bulan dibawa ke RSUD Prof. Dr. Margono Soekarjo oleh orangtuanya dengan keluhan kelemahan anggota gerak sebelah kiri sejak 1 bulan sebelumnya. Pasien rujukan dari salahsatu rumahsakit daerah. Setelah dilakukan tindakan pemeriksaan penunjang, maka disimpulkan dengan diagnosa sementara primitive neuroectoderm tumor (PNET). Pasien direncanakan untuk dilakukan tindakan opeasi bedah saraf elektif. Tindakan anestesi bedah saraf berlangsung selama 180 menit. Selama berlangsungnya operasi pasien mengalami henti jantung (cardiac arrest) pada menit ke-120. Kemudian dilakukan tindakan resusitasi kardiopulmoner. Pasien merespon resusitasi dengan baik. Pasien pasca operasi dibawa ke ruang perawatan intensif. Pasien dirawat di ruang perawatan intensif selama 6 hari, dirawat di ruang bedah saraf selama 4 hari, dan dipulangkan pada hari ke-10 pasca operasi.Intraoperative Cardiac Arrest in Pediatric NeuroanesthesiaIntra-operative cardiac arrest is the most frightening complication during surgery, especially in cases of pediatric neurosurgery, because it will affect the outcome of the operation and the long-term effects it causes. A more severe risk is death at the operating table. A 10-month-old girl was brought to the RSUD Prof. Dr. Margono Soekarjo by his parents with complaints of weakness in the left limb since 1 month before. Patient referral from one regional hospital. After carrying out investigative actions, it is concluded with a provisional diagnosis of primitive neuroectoderm tumor (PNET). Patients are planned for elective neurosurgery surgery. The neurosurgical anesthetic procedure lasts 180 minutes. During the operation, the patient experiences cardiac arrest (cardiac arrest) in the 120th minute. Then cardiopulmonary resuscitation is performed. Patients respond to resuscitation. Postoperative taken to intensive care. The patient was treated in the intensive care room for 6 days, was admitted to the neurosurgical room for 4 days, and sent home on the 10th day postoperatively.

Transcranial Doppler Ultrasonography: Diagnosis dan Monitoring Non Invasif pada Neuroanesthesia dan Neurointesive Care Laksono, Buyung Hartiyo
Jurnal Neuroanestesi Indonesia Vol 6, No 2 (2017)
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Transcranial Doppler (TCD) adalah pemeriksaan ultrasonografi yang telah digunakan secara luas dibidang neuroanestesi dan perawatan intensif. Pada bidang perawatan intensif neurologi, pemeriksaan TCD sangat berguna untuk evaluasi dan monitoring perubahan sirkulasi pembuluh darah penting di otak, seperti arteri serebri media (middle cerebral artery-MCA), arteri serebri anterior (anterior cerebral artery-ACA), arteri carotis interna (internal carotid artery-ICA) cabang terminalis, arteri cerebri posterior (posterior cerebral artery-PCA), arteri vertebralis dan arteri basilaris. Selain kecepatan aliran, pemeriksaan ini juga dapat digunakan untuk evaluasi perubahan diameter pembuluh darah. TCD digunakan untuk pemeriksaan penunjang diagnostik perdarahan subarachnoid, monitoring vasospasme dan deteksi peningkatan tekanan intrakranial (TIK), evaluasi hemodinamik cerebral pada kasus trauma kepala, serta sebagai alat bantu penentuan kasus kematian otak. Pada tindakan pembedahan saraf atau neurosurgery, TCD sangat berguna dalam deteksi dini adanya mikroemboli.Transcranial Doppler Ultrasonography: Diagnosis and Monitoring non Invasive in Neuroanesth and Neurointensive CareTranscranial Doppler (TCD) is ultrasound examination which is already widely used in the field of neuroanesthesia and intensive care. In the field of neurology intensive care, TCD examination is very useful for the evaluation and monitoring of significant changes in the circulation of main cerebral blood vessels, such as the middle cerebral artery (MCA), anterior cerebral artery (ACA), terminal branches of internal carotid artery (ICA), posterior cerebral artery (PCA) , the vertebral artery and the basilar artery. In addition to the flow velocity, the examination can also be used to evaluate changes in the diameter of blood vessels. TCD is used for diagnostic investigation of subarachnoid hemorrhage, vasospasm monitoring and detection of elevated intracranial pressure (ICP), evaluation of cerebral hemodynamics changes in cases of head injury, as well as aids for determination of brain death cases. In neurosurgery, TCD is very useful in the early detection of microemboli.

Penatalaksanaan Anestesia pada Pasien Cretin dengan Hipopituitarisme Sekunder Akibat Kraniofaringioma Rahardjo, Theresia Monica; Fuadi, Iwan; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 1, No 3 (2012)
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Kraniofaringioma adalah tumor sela dan parasela, yang merupakan 6-10% tumor otak pada anak-anak. Gejala umum merupakan tanda peningkatan tekanan intrakranial, seperti sakit kepala, muntah dan gangguan penglihatan. Disfungsi endokrin yang nyata merupakan gambaran umum kraniofaringioma akibat lokasi tumor terhadap kelenjar hipotalamus dan pituitari. Fisik pendek ditemukan pada 50-86% pasien dengan laju pertumbuhan subnormal dan pubertas yang terlambat. Seorang laki-laki, umur 20 tahun, pasien kretin dengan hipopituitarisme sekunder menjalanicraniotomy tumor removal dan penempatan omaya shunt. Dia memiliki riwayat sakit kepala sejak 13 tahun yang lalu disertai dengan gangguan penglihatan yang dimulai dari mata kiri dan saat ini dia buta. Dia juga menderita kegagalan pertumbuhan dan pubertas yang terhambat, memiliki fisik seorang anak laki-laki, dengan tinggi badan 140 cm dan berat badan 40 kg. Dia memiliki TSHs yang meningkat dengan T3 dan fT4 yang normal, LH dan FSH yang menurun, prolaktin yang normal, hormon pertumbuhan yang normal rendah dan kortisol yang menurun. Teknik anestesia yang digunakan adalah anestesia umum. Induksi dengan fentanyl, pentotal, lidocaine dan vecuronium dengan kombinasi N2O/O2 dan isoflurane. Rumatan anestesi dengan isoflurane dan kombinasi O2/udara. Pernapasan pasien dikontrol dengan dosis inkremental vecuronium untuk mempertahankan relaksasi. Mannitol dan furosemide diberikan untuk menurunkan tekanan intrakranial. Operasi berlangsung selama 5 jam. Setelah 5 hari di ICU, pasien dapat kembali keruangannya di Kemuning. Masalah pasien ini adalah peningkatan tekanan intrakranial, disfungsi endokrin dan kemungkinan kesulitan jalan napas akibat bentuk tubuh yang kecil. Kortikosteroid sebagai terapi penggantian hormonal diberikan sebelum operasi. Dosis obat anestesi disesuaikan dengan berat badan. Intubasi menggunakan laryngoscope blade dan endotracheal tube dengan ukuran lebih kecil. Selama operasi dihindari pemakaian nitrous oxide, digunakan konsentrasi rendah anestesi inhalasi dan penggunaan dominan anestesi intravena. Pemantauan post operatif dilakukan di ICU dengan memperhatikan kemungkinan komplikasi hormonal seperti diabetes insipidus dan hiponatremia selain pengelolaan nyeri post operatif. Pasien dengan penyakit pituitari, dalam kasus ini kraniofaringioma, disertai dengan disfungsi endokrin dan pertumbuhan abnormal, membutuhkan penatalaksanaan preoperatif, intraoperatif dan postoperatif yang sangat teliti. Kerjasama yang baik antara bagian anestesi, bedah dan endokrinologi dapat menurunkan morbiditas dan mortalitas pada penyakit ini.Anesthesia Management In Cretin Patient With Hypopitutarism Secondary Of CraniopharyngiomaCraniopharyngioma is a sellar and parasellar tumor, which accounts to 6-10% of childhood brain tumors. Common symptoms are signs of increase intracranial pressure, like headache, vomiting and visual dysfunction. A significant endocrine dysfunction is an usual feature of craniopharyngioma due to the proximity of the tumor to hypothalamus and pituitary gland. Short statue found in 50-86% patient with subnormal growth rates and delayed puberty. A male, 20 yrs cretin patient with hypopituitarism secondary of craniopharyngioma had a craniotomy tumor removal and placement of omaya shunt. He had a history of headache since 13 yrs ago accompanied by visual disturbance, started from his left eye, now he is totally blind. He also suffered from growth failure and delayed puberty, has a physic of a boy regardless his age as 20 yrs old adult, with height 140 cm and weight 40 kg. He has an elevated TSHs but normal T3 and fT4, a decreased LH and FSH, a normal prolactin, a normal but low growth hormon and a decreased cortisol. Anesthetic technique used was general anesthesia. Induction was done with fentanyl, pentotal, lidocaine and vecuronium with a mixture of N2O/O2 and isoflurane. Anesthesia was maintained with isoflurane and a mixture of O2/air. Patient was in controlled breathing with an incremental dose of vecuronium to maintaine the relaxation. Mannitol and furosemide were given to reduce intracranial pressure. The procedure took about 5 hours. After 5 days ICU stayed, the patient was referred back to his room at Kemuning. The problems in this patient are a raised of intracranial pressure, an endocrine dysfunction and a possibility of airway difficulty related to his short statue. Corticosteroid as hormone replacement therapy was given before the operation. Based on his short statue, induction dose of anesthetic agents were adjusted and smaller laryngoscope blade and endotracheal tube were used for intubation. Avoidance of nitrous oxide, low concentration of volatile agent and dominant used of intravenous anesthetic agent were applied during the operation. Post operative monitoring was done in ICU with specific concern of hormone complications like diabetes insipidus and hyponatremia beside post operative pain control. Patient with pituitary disease, in this case craniopharyngioma, accompanied by endocrine dysfunction and abnormal growth, need a very careful treatment from preoperative, intraoperative to postoperative period. A good management and cooperation between anesthesiologist, surgeon and endocrinologist can reduce the morbidity and mortality in this kind of disease.

Penerapan Enhanced Recovery after Surgery (ERAS) pada Bedah Saraf Firdaus, Riyadh; Permana, Affan Priyambodo; Sugianto, Astrid Indrafebrina; Theresia, Sandy
Jurnal Neuroanestesi Indonesia Vol 10, No 2 (2021)
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Enhanced recovery after surgery atau ERAS adalah suatu protokol perawatan perioperasi terstandar multidisiplin pada pasien bedah yang bertujuan untuk meminimalkan stres perioperasi sehingga menghasilkan luaran yang lebih baik. Protokol ERAS tersusun dari berbagai komponen perawatan yang terbukti mendukung pemulihan dan/atau menghindari komplikasi pascaoperasi. Komponen-komponen tersebut mengikutsertakan ahli bedah, ahli anestesi, perawat, farmasi, ahli gizi yang terlibat dalam perawatan pasien sehingga memberikan perbaikan yang lebih baik. Protokol ERAS tersusun dari berbagai komponen perawatan dari mulai praoperasi (konseling, pemberian nutrisi, pengelolaan kebiasaan, trombofilaksis, persiapan daerah operasi dan profilaksis antimikroba), intraoperasi (teknik anestesi, manajemen anestesi, analgesia, manajemen cairan, pengaturan suhu, teknik pembedahan) hingga pascaoperasi (kejadian post-operative nausea and vomiting (PONV), drainase urin, asupan nutrisi, mobilisasi dini). Penerapan ERAS menunjukkan hasil yang baik, dapat diterapkan, dan memberikan keuntungan bagi pasien bedah saraf. Walau demikian, protokol ERAS dalam bedah saraf masih sangat terbatas dan memerlukan penelitian lebih lanjut mengikuti berbagai jenis tindakan/operasi dan keadaan pasien yang berbeda-beda.Implementation of Enhanced Recovery after Surgery (ERAS) in NeurosurgeryAbstractEnhanced recovery after surgery (ERAS) is a multidisciplinary standardized perioperative treatment protocol in surgical patients that aims to minimize perioperative stress and result in better outcomes. The ERAS protocol is composed of various components of care that have been shown to support recovery and/or avoid postoperative complications. These components include surgeons, anesthesiologists, nurses, pharmacists, nutritionists who are involved in patient care to provide better improvements. The ERAS protocol is composed of various components of preoperative care (counseling, nutrition, lifestyle management, thromboprophylaxis, preparation of the surgical area and antimicrobial prophylaxis), intraoperative care (anesthetic technique, anesthesia management, analgesia, fluid management, temperature regulation, surgical technique) and postoperative care (PONV management, urinary drainage, nutritional intake, early mobilization). Implementation of ERAS is applicable and shows good results along with the benefits for patients undergoing neurosurgery. However, ERAS in neurosurgery is still very limited and requires further research following different types of procedures / operations and different patient conditions.

Reaktif Oksigen Spesies Pada Cedera Otak Traumatik Suarjaya, I Putu Pramana; Bisri, Tatang; Wargahadibrata, A. Himendra
Jurnal Neuroanestesi Indonesia Vol 1, No 2 (2012)
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Cedera otak traumatik menyebabkan mortalitas dan morbiditas karena terjadinya cedera primer yang diikuti oleh cedera sekunder. Cedera sekunder yang terjadi meliputi peningkatan asam amino eksitatif, ketidak seimbangan ion, penurunan kadar ATP, aktivasi enzim proteolitik dan stres oksidatif yang akan menyebabkan terjadinya disfungsi neuron sampai kematian neuron. Terdapat kaitan erat antara beratnya stres oksidatif yang terjadi dengan beratnya cedera otak yang terjadi, sebagai akibat terganggunya hemostasis kalsium, gangguan pembentukan energi dan meningkatnya proses peroksidasi lipid. Pada telaah ini didiskusikan bagaimana stres oksidatif yang terjadi pada cedera otak traumatik, dan pengaruhnya pada proses pathologi sedera otak traumatik.Reactive Oxygen Species in Traumatic Brain InjuryTraumatic Brain Injury (TBI) morbidity and mortality are due to primary and secondary injury. Primary injury is due to mechanical forces during the trauma process and secondary injury is subsequent process following the primary impact. This secondary injury processes involving increased excitatory amino acids, ionic imbalance, decreased ATP level, unusual proteolytic enzyme activity, and oxidative stress which contibute to delayed neuronal dysfunction and neuronal death. The mammalian brain is vulnerable to oxidative stress because of the high oxygen consumption needed for maintaining neuronal ion homoeostasis during the propagation of action potentials.There is a close relationship between degree of oxidative stress and severity of brain insults, which results from a perturbation of calcium homeostasis, energy metabolism, and increased lipid peroxidation. In this review we discuss oxidative stress during traumatic brain injury, and its implication on pathology of traumatic brain injury.

Tatakelola Ventilasi Mekanik pada Pengangkatan Tumor Metastasis Ekstradura Torakal dengan Teknik Anestesi Satu Paru dan Posisi Lateral Dekubitus Putri, Dini Handayani; Bisri, Dewi Yulianti; Fuadi, Iwan; Harahap, M Sofyan
Jurnal Neuroanestesi Indonesia Vol 9, No 1 (2020)
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Spinal adalah lokasi yang paling umum untuk metastasis tulang. Metastasis spine dapat menyebabkan nyeri, ketidakstabilan tulang belakang dan cedera neurologis lainnya. Pada operasi tumor spinal metastasis pendekatan pembedahan menjadi hal penting baik bagi ahli bedah saraf maupun neuroanestesi. Pada kasus ini laki-laki 60 tahun dengan tumor ekstradura metastasis torakal akan menjalani operasi pengangkatan tumor dan stabilisasi dengan pendekatan posterolateralextracavity untuk mendapat akses yang optimal ke bagian ventral spinal bagian torakal atas. Pasien di induksi dengan fentanil 200 mcg dan propofol 100 mg, fasilitasi intubasi dengan rocuronium 50 mg dan pemasangan double lumen tube kiri, posisi lateral dekubitus. Ketika dilakukan ventilasi satu paru pasien mengalami kejadian desaturasi oksigen sampai 93%, dilakukan penyesuaian mode ventilator sebagai penanganannya. Pascaoperasi pasien tidak diekstubasi dan menjalani perawatan diruangan intensif selama dua hari dan dipulangkan pada hari ke 13. Tatakelola kasus ini difokuskan pada penilaian preoperatif, pengaruh posisi lateral dekubitus dan teknik anestesi satu paru terhadap fungsi respirasi dan kardiovaskular. Risiko hipoksemia akibat ketidaksesuaian ventilasi / perfusi yang menyebabkan gangguan oksigenisasi dan perfusi terhadap otak dan medulla spinalis, sehingga diperlukan tatakelola ventilasi mekanik, monitoring intraoperasi yang berhubungan dengan kaidah-kaidah neuroproteksi terhadap otak dan medulla spinalis.Management of Mechanical Ventilation in the Removal of Thoracal Extradura Metastatic Tumors with One Lung Anesthesia Technique in Decubitus Lateral PositionAbstractThe spine is the most common location for bone metastases. Spine metastases can cause pain, spinal instability and other neurological injuries. In spinal metastatic tumor surgery a surgical approach is important for both neurosurgeons and neuroanesthesiologists. In this case, a 60-year-old man with a thoracic metastatic extradura tumor would undergo tumor removal and stabilization with the posterolateralextracavity approach to obtain optimal access to the ventral spinal ventral region. Patients were induced with 200 mcg fentanyl and propofol 100 mg, facilitation of intubation with 50 mg rocuronium and installation of the left double lumen tube, lateral decubitus position. When one lung is ventilated, the patient experiences an oxygen desaturation event of up to 93%, adjusting the ventilator mode as a treatment. Postoperatively the patient was not extubated and underwent intensive care for two days and was discharged on day 13. The case management focused on preoperative assessment, the influence of lateral decubitus position and one-pulmonary anesthetic technique on respiration and cardiovascular function. The risk of hypoxemia due to ventilation / perfusion mismatches that cause oxygenisation and perfusion disorders of the brain and spinal cord, so that management of mechanical ventilation, intraoperative monitoring associated with neuroprotection rules of the brain and spinal cord.

Penanganan Perioperatif Pasien Pediatrik dengan Cedera Kepala Berat Halimi, Radian Ahmad; Umar, Nazaruddin; Saleh, Siti Chasnak; Rehatta, Nancy Margareta
Jurnal Neuroanestesi Indonesia Vol 5, No 2 (2016)
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Cedera otak traumatika (COT) merupakan penyebab kematian dan kecacatan terbesar di Amerika dan negara industri lainnya di dunia. Anak dari usia balita hingga remaja yang mengalami cedera otak berat biasanya akan dapat menghadapi kecacatan yang signifikan selama beberapa dekade. Seorang anak laki-laki berumur 3 tahun dengan diagnosa cedera kepala berat akibat perdarahan subdural di temporo occipital kiri dan fraktur terdepresi yang disebabkan karena jatuh dari ketinggian tiga meter, direncanakan dilakukan kraniektomi dekompresi karena terjadi penurunan kesadaran signifikan. Berbagai komplikasi dan permasalahan terjadi yakni perdarahan masif intraoperatif, edema otak kongestif disertai demam pascaoperasi di ruang perawatan intensif, hingga akhirnya pasien dapat pindah ke ruang perawatan biasa dan dilakukan rawat jalan. Penanganan COT berat memerlukan kemampuan seorang ahli anestesi dalam melakukan resusitasi otak dengan ABCDE neuroanestesi, kontrol terhadap hipertensi intrakranial, neuroproteksi dan neurorestorasi.Perioperative Treatment Pediatric Patients with Head InjuriesTraumatic brain injury (TBI) is the largest cause of death and disability in the United States and other industrialized countries in the world. Young age patient who suffered severe TBI typically face significant disability for decades. A 3 years old boy with diagnosis of severe TBI as a result of subdural hemorrhage in the left temporo occipital and fracture depressed due to fall from a height of three meters, was planed to perform decompresive craniectomy because decreased conciouseness significantly.Various complications and problems occur, intraoperative masive bleeding, postoperative diffuse brain edema with persistent hyperthermia on the intensive care unit, until the patient can be moved to a regular ward and can be done outpatient. The management of severe head injury requires the ability of an anesthesiologist in performing brain resuscitation with ABCDE neuroanesthesia, control of intracranial hypertension and neurorestoration.

Metabolisme Energi pada Cedera Otak Traumatik Suarjaya, I Putu Pramana; Bisri, Tatang; Wargahadibrata, A. Himendra
Jurnal Neuroanestesi Indonesia Vol 1, No 4 (2012)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Cedera otak traumatik mengakibatkan terjadinya kaskade gangguan fisiologi dan biokimia yang berpengaruh pada metabolisme dan produksi energi serebral. Setelah cedera otak traumatik, terjadi perubahan berkelanjutan pada metabolisme energi serebral yang ditandai oleh terjadinya disfungsi mitokondria dan meningkatnya glikolisis. Cedera otak traumatik juga mengakibatkan adanya peningkatan kebutuhan energi karena terjadinya gangguan hemostasis ion, gangguan hantaran glutaminergik dan proses perbaikan jaringan yang membutuhkan energi. Kombinasi dari dari pelepasan ATP dari sinap preterminal, disfungsi mitokondria, penurunan aliran darah otak setelah cedera dan peningkatan kebutuhan energi otak pada saat cedera akan menimbulkan ketidak seimbangan antara penyediaan dan kebutuhan energi pada cedera otak traumatik.Energy Metabolism in Traumatic Brain InjuryDuring Traumatic brain injury, secondary insults will led to physiological and biochemical cascade that disturbing cerebral energy metabolism. After traumatic brain injury, sustained changes in cellular energy metabolism have been described as accelerated glycolysis or mitochondrial dysfunction.Traumatic brain injury is associated with increasing energy needs to restore cerebral ionic hemostasis, distubance in glutaminergic process and tissue repairing. Combination of ATP release from pre-terminal synaps, mitochondrial dysfunction, decrease brain oxygen delivery and increasing energy metabolic needs results in cerebral energy imbalances.

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Agni Susanti

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Agni Susanti

Contact Email jurnalneuroanestesi@gmail.com

Phone +6287722631615

Journal Mail Official jni@inasnacc.org

Editorial Address Jl. Prof. Eijkman No. 38 Bandung 40161, Indonesia Lt 4 Ruang JNI

Location , INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Agni Susanti

Contact Email
jurnalneuroanestesi@gmail.com

Phone
+6287722631615

Journal Mail Official
jni@inasnacc.org

Editorial Address
Jl. Prof. Eijkman No. 38 Bandung 40161, Indonesia Lt 4 Ruang JNI

Location
,

INDONESIA