cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Zahratul Aini
Contact Email
dr.zahratulaini@unsyiah.ac.id
Phone
+62812388847262018
Journal Mail Official
m.zainudin@uii.ac.id
Editorial Address
Jl. Kaliurang Km 14,5 Yogyakarta, Indonesia
Location
Kab. sleman,
Daerah istimewa yogyakarta
INDONESIA
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 468 Documents
 20   21   22   23   24 
Relationship polymorphism exon 17 of insulin receptor (INSR) gene with polycystic ovarian syndrome among Malay ethnic in South Sumatera Okta Emilia; Legiran; Safyudin; Syifa Alkaf
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art3

Abstract

Background: A sedentary lifestyle is a risk of obesity. One of the negative effects of obesity is insulin resistance. Insulin resistance is found in 50% - 90% of women with Polycystic Ovary Syndrome (PCOS).Objective: This study aimed to analyse the relationship polymorphism exon 17 of insulin receptor (INSR) gene in Malay ethnicity in South Sumatera.Methods: This is an observational analytic study with a case-control design conducted at the Molecular Biology Laboratory, Faculty of Medicine, Sriwijaya University. This study sample used blood taken from 80 people consisting of 40 cases and 40 controls. Genotyping and allotypic were performed using PCR-RFLP. Analysis was performed using SPSS 16.Results: The statistical analysis using the Chi-Square test on IMT resulting p-value = 0.003 (OR = 4.660 95% CI = 1.764 - 12.311). (Wild type) CC, (Mutant heterozygous) CT, (Homozygous Mutant) TT. The statistical analysis using the Pearson Chi-Square Genotype PCOS resulting p-value = 0.970 and fisher exact test on SOPK allotype resulting p-value = 0.500 (OR = 0.949 95% CI = 0.503 - 1,790).Conclusion: In conclusion, there was a significant relationship between BMI and PCOS among Malay ethnic in South Sumatera. There was no significant relationship between genotypic polymorphism and allotype exon 17 of INSR with PCOS in Malay ethnic groups in South Sumatera.
Pulmonary tuberculosis in gestational patient with diabetes mellitus in regional public hospital Dumai, Riau Province: a case report Marsita Ayu Lestari; Amrizal Amir
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 2, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/10.20885/JKKI.Vol10.Iss2.art14

Abstract

Diabetes mellitus increases the risk of pulmonary tuberculosis, whereas pulmonary tuberculosis can aggravate glycemic control. Pulmonary tuberculosis with diabetes mellitus in pregnancy is the complex problems to concern about maternal and fetal complications. We report a 38-year-old pregnant woman with a bloody cough for two days as a chief complaint-volume ± 400 millilitres in every cough. She also complained a chronic cough, dyspnea, fatigue and weight loss approximately eight kg in six months. Four months ago, she had a bloody cough one tablespoon.  The patient was hospitalized. The patient also felt thirsty and urinate frequently, but she did not check the plasma glucose level. The patient had a baby with weight birth 4600 gram, her son 3 year-old received TB drugs and her sister with diabetes mellitus. In physical examination, pale conjunctiva, and crackles in the lower region of the right lung and all regions of the left lung. The results of laboratory are Hb 10.7 g/dL, monosit 11%, ESR 31%, fasting plasma glucose 137 mg/dl, A1C 7.3%, spot 3+ early morning 3+ spot 2+ (sputum). A chest x-ray showed an infiltrate in the field of the left lung. The patient had a pulmonary tuberculosis and diabetes mellitus in pregnancy. The patient was cared by internist, obstetrician and nutritionist.pulmonary tuberculosis and diabetes mellitus in pregnancy can increase morbidity of maternal and fetal. Evaluation of plasma glucose level was needed to determine diagnosis of type 2 diabetes mellitus or gestational diabetes. Integrated management of internist, obstetrician and nutritionist were needed to treat it. 
An unusual cause of eyeball rupture: a case report Handy Darmawan
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 2, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/10.20885/JKKI.Vol10.Iss2.art13

Abstract

Eyeball rupture due to ocular trauma is a major public health problem with a high global incidence. In contrast, non-trauma case of spontaneous eyeball rupture is extremely rare and is never been reported in Indonesia. In this report, we present a patient with spontaneous right eyeball rupture due to acute glaucoma secondary to hyper mature cataract. Although eyeball rupture in both trauma and non-trauma cases have the same poor outcome, non-trauma case of spontaneous eyeball rupture is preventable. Therefore, proper management and evaluation of the patients with cataract and glaucoma are necessary to avoid this rare and devastating outcome.
The hypoglicemic effects of tapak liman (Elephantopus scaber L) plant extract on albino rat (Rattus novergicus) models of diabetes mellitus Tri Agusti Sholikah; Sri Wulandari; Indah Ariesta; Muhammad Arif Rakhman Hakim; Muhammad Hafizhan
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 2, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss2.art10

Abstract

Background: Diabetes mellitus (DM) is among the diseases with high morbidity and mortality The pathogenesis of DM involves pancreatic ß-cell damage or insulin sensitivity disorder that result in hyperglycemia. Tapak liman (Elephantopus scaber L) is known to have high flavonoid content. Flavonoids are antioxidants that play a role in reducing pancreatic ß-cell damage or damage to other tissues, which potentially reduce blood glucose levels.Objective: To determine the hypoglycemic effects of tapak liman using the DM rat models.Methods: Twenty-eight Wistar albino rats (Rattus novergicus) were divided into four groups: the normal control group (KKn), not induced by streptozotocin-nicotinamide (STZ-NA) intraperitoneal; negative control group (KK-), induced by STZ-NA; treatment group 1 (KP1), induced by STZ-NA and 150 mg/kg body weight of tapak liman plant extract; and the treatment group 2 (KP2), induced by STZ-NA and 300 mg/kg body weight of tapak liman. Blood glucose levels were measured on the 7th day after STZ-NA induction and the 28th day after the administration of tapak liman plant extract. The results were analyzed for statistical significance.Results: There was a significant decrease in blood glucose levels in KP1 and KP2 (p= 0.05). The decrease in blood glucose in KP1 had not reached normal levels compared to KP2.Conclusion: Administration of tapak liman plant extract at a dose of 300 mg/kg body weight in DM rat models reduced blood glucose levels to normal.
PERBEDAAN MORFOLOGI DAN FRAGMENTASI DNA PADA SPERMATOZOA TIKUS PUTIH (Rattus norvegicus) GALUR WISTAR PASCA INDUKSI BERBAGAI MODEL STRES SLEEP DEPRIVATION Norina Agatri; Fitranto Arjadi; Lantip Rujito
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 3, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss3.art4

Abstract

Background: A stress, sleep deprivation, can cause imbalance of reactive oxygen species (ROS) that can damage DNA, lipids and proteins of spermatozoa, consequently leading to infertility.Objective: The aim of this study is to investigate differences of morphology and DNA fragmentation with some models of sleep deprivation in spermatozoa of white male Wistar rat strain (Rattus novergicus).Methods: This study was an experimental study with post-test-only with control group design. There were 30 male Wistar rats which were randomly divided into 5 groups: control group, paradoxical sleep deprivation (PSD) group, total sleep deprivation (TSD) group, sleep recovery (SR) group, PSD group + SR group, and TSD group + SR group. Stress induction was conducted for 5 days. Morphological abnormality of spermatozoa was observed by creating sperm removal tinged by eosin and nigrosine. DNA fragmentation was performed by determining DNA fragmentation index (DFI). Morphological data of spermatozoa were analysed by One-Way Annova and Post-Hoc Turkey test, and DNA fragmentation of spermatozoa was analysed by Kruskal Wallis and Mann Whitney test to determine differences among the groups.Results: The highest mean of the abnormal morphology was in PSD Group (89.5 %, p=0.004). The normal mean of DNA fragmentation was found in control group, PSD+SR group and TSD+SR group, PSD and TSD groups. Bad DNA fragmentation index was found in PSD and TSD groups (30.16% and 31.4%, p=0.023).Conclusion: There were differences of morphology and DNA fragmentation of the spermatozoa in the male Wistar rat strain induced by various models of sleep deprivation.
Rhabdomyosarcoma metastases to the bone marrow of a 2-year-old male patient: A case report Tri Ratnaningsih; Wirimena Hurimah
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 2, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss2.art13

Abstract

Rhabdomyosarcomas are the most common pediatric soft tissue sarcomas. However, rhabdomyosarcoma cases that manifest as a systemic disease or showing diffuse metastasis in the bone marrow are sporadic. The most common sites of metastasis due to rhabdomyosarcoma include lungs, lymph nodes, and bone marrow. The bone marrow involvement is seen in about 30% of cases of metastasis. We report a case of a 2-year-old boy with complaints of right eye protrusion. The result of a head CT-scan arouses suspicion of rhabdomyosarcoma. On physical examination, protrusion of the eye and swelling of the neck with a fixed and flat surface were observed. Peripheral blood examination resulted in pancytopenia (hemoglobin: 4 g/dL, leukocytes: 3,490 cells/µL, platelets: 16,000 cells/µL). The peripheral blood morphologies showed lymphoblasts and myeloblasts, whereas the bone marrow biopsy result showed infiltration of tumour cells (rosette cell form). Chest imaging examination showed suspected of skeletal metastases in bilateral scapulae and bilateral costae. Pancytopenia with tumour cells metastasis to the bone marrow was found in this case. Diagnosis of rhabdomyosarcoma with multiorgan metastasis and the presence of tumour cells in the bone marrow was based on clinical features, physical examination, laboratory examinations, and other supporting investigations.
Diagnostic challenge in parathyroid carcinoma with multiple pathological bone fracture: A case report Hermin Aminah Usman; Hasrayati Agustina; Zahra Nurusshofa; Siska Dwiyantie Wahyuni
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 1, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss1.art14

Abstract

Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. It often presents with unspecified clinical manifestation that leads to misdiagnosis. We report a case of a 36-year-old woman who suffered from multiple bone tumours and recurrent bone fracture for 3 years ago, and misdiagnosis as only a giant cell tumours of the bone. Then, the patient continued to develop another mass in the neck that kept growing and the mass move on swallowing. The clinician diagnosed her as a colloid goitre based on cytological examination from fine-needle aspiration biopsy. Elevated parathyroid hormone level, hypercalcemia, and suspected parathyroid adenoma in the Sestamibi Parathyroid scan led the clinician to perform a frozen section in this patient with subsequent histopathological of diagnosis as parathyroid carcinoma. The diagnosis of parathyroid carcinoma continues to be a challenge. Understanding the pathogenesis and multidisciplinary collaboration is important to define an accurate diagnosis and treatment. 
Comparing tools of balance tests in assessing balance of middle-aged women with or without exercises Nawanto Agung Prastowo; Michelle Olivia Budiarta; Kidyarto Suryawinata; Ignatio Rika Haryono
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 11, No 1, (2020)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol11.Iss1.art4

Abstract

Background: Fall risks among middle-aged women are relatively high. However, there is a lack of studies on tools of balance tests and their accuracy among middle-aged women. Objective: The aim of this study is to compare three tools of balance tests to predict falls of middle-aged women who exercise regularly and who do not. Methods: Eighty-five middle-aged women (50-64 years old) were included in this study, and 40 women of them (47.1%) exercised regularly. The Berg Balance Scale (BBS), Timed Up and Go Test (TUG), and 30-second Chair Stand Test (30-s CST) were the tools examined in this study. The numerical data of this study were analyzed by using a Mann-Whitney test. Those were significant if p<0.05. Accuracy of the tools of balance tests was evaluated by using Receiver Operating Characteristic (ROC) curve. Area under the curve (AUC) was significant if =0.70.Results: Based on this study, the middle-aged women (EG) indicated lower score of TU than sedentary (SG) test (6.9 ± 0.9 vs 8.3 ± 1.7, p = <0.000), and higher score of 30-s than sedentary (SG) test (20.1 ± 3.6 vs 17.2 ± 5.6, p = 0.026). Three participants (3.53%) reported history of falls. The TUG test had better accuracy to predict the falls (AUC 0.922, 95% CI 0.840 - 1.005, sensitivity 1.00, specificity 0.84, p=0.013). Mostly, the participants (˜70%) preferred to practice Tai Chi and Yoga. Conclusion: The middle-aged women who exercised could have a better score of the balance tests, and the TUG test could predict falls of them.
Fragmented teaching and compartmentalized learning Cheng Hwee Ming
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 2, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol10.Iss2.art1

Abstract

No abstract
Delayed lactogenesis II and unsuccessful exclusive breastfeeding Miranti Dewi Pramaningtyas
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 10, No 2, (2019)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol10.Iss2.art2

Abstract

No abstract

Page 22 of 47 | Total Record : 468

 20   21   22   23   24 

Filter by Year

2009 2025


Reset
Filter By Issues
All Issue JKKI, Vol 16, No 2, (2025) JKKI, Vol 16, No 1, (2025) JKKI, Vol 15, No 3, (2024) JKKI, Vol 15, No 2, (2024) JKKI, Vol 15, No 1, (2024) JKKI, Vol 14, No 3, (2023) JKKI, Vol 14, No 2, (2023) JKKI, Vol 14, No 1, (2023) JKKI, Vol 13, No 3, (2022) JKKI, Vol 13, No 2, (2022) JKKI, Vol 13, No 1, (2022) JKKI, Vol 12, No 3, (2021) JKKI, Vol 12, No 2, (2021) JKKI, Vol 12, No 1, (2021) JKKI, Vol 11, No 3, (2020) JKKI, Vol 11, No 2, (2020) JKKI, Vol 11, No 1, (2020) JKKI, Vol 10, No 3, (2019) JKKI, Vol 10, No 2, (2019) JKKI, Vol 10, No 1, (2019) JKKI, Vol 9, No 3, (2018) JKKI, Vol 9, No 2, (2018) JKKI, Vol 9, No 1, (2018) JKKI, Vol 8, No 3, (2017) JKKI, Vol 8, No 2, (2017) JKKI, Vol 8, No 1, (2017) JKKI, Vol 7, No 5, (2016) JKKI, Vol 7, No 4, (2016) JKKI, Vol 7, No 3, (2016) JKKI, Vol 7, No 2, (2015) JKKI, Vol 7, No 1, (2015) JKKI, Vol 6, No 4, (2015) JKKI, Vol 6, No 3, (2014) JKKI, Vol 6, No 2, (2014) JKKI, Vol 6, No 1, (2014) JKKI, Vol 5, No 2, (2013) JKKI, Vol 5, No 1, (2013) JKKI, Vol 3, No 8, (2011) JKKI, Vol 2, No 6, (2010) JKKI, Vol 2, No 5, (2010) JKKI, Vol 1, No 3, (2009) JKKI, Vol1, No 1, (2009) More Issue